Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Eduardo Vilar"'
Autor:
Jessica Omark, Eduardo Vilar, Y Nancy You, Leslie Dunnington, Sarah Noblin, Blair Stevens, Maureen Mork
Publikováno v:
Hereditary Cancer in Clinical Practice, Vol 18, Iss 1, Pp 1-9 (2020)
Abstract Background Individuals who have colorectal or endometrial cancers displaying loss of immunohistochemical staining of one or more mismatch repair proteins without an identifiable causative germline pathogenic variant have unexplained mismatch
Externí odkaz:
https://doaj.org/article/16faa9cc0da04b148e87de9fc592892b
Autor:
Prashant V. Bommi, Alejandro Francisco-Cruz, Ignacio I. Wistuba, Winfried Edelmann, Jason Willis, Samir M. Hanash, Wenhui Wu, Laura Reyes-Uribe, Krishna M. Sinha, Paul Scheet, Melissa W. Taggart, Edwin R. Parra, Hiroyuki Katayama, Hong Wu, Patrick M. Lynch, Pedro Rocha, Zuhal Ozcan, Jared K. Burks, Eduardo Vilar, Elena Tosti, Charles M. Bowen
Publikováno v:
Cancer Res
Lynch syndrome is the most common cause of hereditary colorectal cancer and is secondary to germline alterations in one of four DNA mismatch repair (MMR) genes. Here we aimed to provide novel insights into the initiation of MMR-deficient (MMRd) color
Autor:
Christian Rolfo, José A. Lorente, Massimo Cristofanilli, Umberto Malapelle, Luis Paz-Ares, Eduardo Vilar, Alessandro Russo, Juan Jose Diaz Mochon, María del Carmen Garrido-Navas, Andrés F. Cardona, María José Serrano, Patrick Pauwels, Luis E. Raez, Antonio J. Ruiz-Rodriguez, Ignacio Gil-Bazo
Publikováno v:
Cancer discovery
Despite major therapeutic progress, most advanced solid tumors are still incurable. Cancer interception is the active way to combat cancer onset, and development of this approach within high-risk populations seems a logical first step. Until now, str
Autor:
Brian K. Bednarski, Jane E. Rogers, Benny Johnson, Terri L. Woodard, Y. Nancy You, Eduardo Vilar, Van K. Morris, George J. Chang, Bryan K. Kee, Cathy Eng, Graciela Mn Gonzalez, John M. Skibber, Miguel A. Rodriguez-Bigas, Arvind Dasari
Publikováno v:
Obstet Med
Background Colorectal cancer in young adults is on the rise. This rise combined with delayed childbearing increases the likelihood of colorectal cancer diagnosed during pregnancy or in the postpartum period. Methods Electronic health records were use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b75973f66cedf45eb6809dba593dd5a
https://europepmc.org/articles/PMC9277731/
https://europepmc.org/articles/PMC9277731/
Autor:
Richard B. S. Roden, Altaf Mohammed, Mark Steven Miller, Robert J. Glynn, Ming You, Zelton D Sharp, Roderick H. Dashwood, Haval Shirwan, Susan R. Mallery, Steven M. Lipkin, Eduardo Vilar, Shadmehr Demehri, Powel H. Brown, Seema A. Khan, Chinthalapally V. Rao, Bryon D. Johnson, Mary L. Disis, Eva Szabo, Peter J. Allen, Raymond N. DuBois, Jill M. Siegfried, Thomas W. Kensler, Karen T. Liby, Andrew T. Chan, Emmanuelle J. Meuillet, Margie L. Clapper, Robert E. Schoen
Publikováno v:
Journal of Cancer Prevention
The Division of Cancer Prevention of the National Cancer Institute (NCI) and the Office of Disease Prevention of the National Institutes of Health co-sponsored the Translational Advances in Cancer Prevention Agent Development Meeting on August 27 to
Autor:
Omer F. Yavuz, Powel H. Brown, Wan Mohaiza Dashwood, Praveen Rajendran, Michelle I. Savage, Roderick H. Dashwood, Ahmet M. Ulusan, Shizuko Sei, Trace A. Gustafson, Eduardo Vilar, Altaf Mohammed, Sabeeta Kapoor
Publikováno v:
Cancer prevention research (Philadelphia, Pa.), vol 14, iss 3
Cancer Prev Res (Phila)
Cancer Prev Res (Phila)
A clinical trial in patients with familial adenomatous polyposis (FAP) demonstrated that sulindac plus erlotinib (SUL+ERL) had good efficacy in the duodenum and colon, but toxicity issues raised concerns for long-term prevention. We performed a bioma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f62f7ed92c43ffaa468ef3e7464079e5
https://escholarship.org/uc/item/9mp7231d
https://escholarship.org/uc/item/9mp7231d
Autor:
Brian K. Bednarski, Y. Nancy You, Miguel A. Rodriguez-Bigas, Ester Borras, Brandee A. Price, Kyle Chang, Maureen E. Mork, Eduardo Vilar, George J. Chang, Funda Meric-Bernstam
Publikováno v:
Diseases of the Colon & Rectum. 62:429-437
Genomic profiling of colorectal cancer aims to identify actionable somatic mutations but can also discover incidental germline findings.The purpose of this study was to report the detection of pathogenic germline variants that confer heritable cancer
Autor:
Andrew Latchford, A. Alonso Sanchez, Patrick M. Lynch, Matthew Mort, Joanna J Hurley, Maria Teresa Ricci, E. Meuser, Marco Vitellaro, Hannah West, A. Backman, Yann Parc, Susan K. Clark, M. R. Aznárez, Frederik J. Hes, Sunil Dolwani, O. Vinet, H. Leon Brito, Maureen E. Mork, Chrystelle Colas, M. Navarro Garcia, S. Gonzalez Romero, Sarah-Jane Walton, Hala Jundi, Gabriel Capellá, S. Kelland, Zeinab Ghorbanoghli, K van der Tuin, Hans F. A. Vasen, Julian R. Sampson, Jan Björk, Evelien Dekker, Jean-Christophe Saurin, Eduardo Vilar, Laura E. Thomas, M. Gonn, Maartje Nielsen
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Gastroenterology, 160(3), 952-954.e4. W.B. Saunders Ltd
Universidad de Barcelona
Gastroenterology, 160(3), 952-954.e4. W.B. Saunders Ltd
Although duodenal adenomas and cancer appear to occur significantly less frequently in autosomal recessive MUTYH-associated polyposis (MAP) than in autosomal dominant familial adenomatous polyposis (FAP),1 current guidelines recommend similar endosco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::370fb1c847676c3c57a5215867e794bc
https://doi.org/10.1053/j.gastro.2020.10.038
https://doi.org/10.1053/j.gastro.2020.10.038
Autor:
Sarah Jane Noblin, Blair Stevens, Y. Nancy You, Jessica Omark, Eduardo Vilar, Maureen E. Mork, Leslie Dunnington
Publikováno v:
Hereditary Cancer in Clinical Practice
Hereditary Cancer in Clinical Practice, Vol 18, Iss 1, Pp 1-9 (2020)
Hereditary Cancer in Clinical Practice, Vol 18, Iss 1, Pp 1-9 (2020)
Background Individuals who have colorectal or endometrial cancers displaying loss of immunohistochemical staining of one or more mismatch repair proteins without an identifiable causative germline pathogenic variant have unexplained mismatch repair d
Autor:
Nina Nelius, Alejandro Hernandez-Sanchez, Yurong Song, Lei Wei, Nan Deng, Winfried Edelmann, Katharina Urban, Ozkan Gelincik, Johannes Gebert, Ali Elsaadi, Elena Tosti, Yan P. Yuan, Vera Fuchs, Matthias Kloor, Mine Oezcan-Wahlbrink, Aysel Ahadova, Eva Maria Katzenmaier, Peer Bork, Jason D. Marshall, Robert H. Shoemaker, Song Liu, Steven M. Lipkin, Mark D. Long, Magnus von Knebel Doeberitz, Shizuko Sei, Asad Umar, Eduardo Vilar, Eduardo Cortes
Publikováno v:
Gastroenterology
Background & Aims DNA mismatch repair deficiency drives microsatellite instability (MSI). Cells with MSI accumulate numerous frameshift mutations. Frameshift mutations affecting cancer-related genes may promote tumorigenesis and, therefore, are share