Zobrazeno 1 - 10
of 72
pro vyhledávání: '"David D.L. Bowtell"'
Autor:
Anil K. Sood, Shama Virani, Kathleen R. Cho, Nicolas Wentzensen, Britton Trabert, Paul D.P. Pharoah, Stephen J. Chanock, Barbara M. Norquist, Jae Weon Kim, Paul Brennan, Keiichi Fujiwara, Usha Menon, Jean Emmanuel Kurtz, Glauco Baiocchi, David D.L. Bowtell, Shelley T. Tworoger, Douglas A. Levine, Citadel J Cabasag, Martin Köbel, Renée T. Fortner
Publikováno v:
Carcinogenesis. 42:785-793
Recently, ovarian cancer research has evolved considerably because of the emerging recognition that rather than a single disease, ovarian carcinomas comprise several different histotypes that vary by etiologic origin, risk factors, molecular profiles
Autor:
Kylie L. Gorringe, Prue E. Allan, Mark S. Carey, Sally Hunter, Anne-Marie Mes-Masson, Anna deFazio, Ian G. Campbell, Dane Cheasley, Diane Provencher, Magnus Zethoven, Cécile Le Page, Dariush Etemadmoghadam, Yunkai Gao, David G. Huntsman, Amy Dawson, Timothy Semple, David D.L. Bowtell, Neville F. Hacker, Marta Llaurado Fernandez, Martin Köbel, Abhimanyu Nigam
Publikováno v:
The Journal of Pathology. 253:41-54
Low-grade serous ovarian carcinoma (LGSOC) is associated with a poor response to existing chemotherapy, highlighting the need to perform comprehensive genomic analysis and identify new therapeutic vulnerabilities. The data presented here represent th
Autor:
Sven Mahner, Robertson Mackenzie, Aline Talhouk, Linda E. Kelemen, Gottfried E. Konecny, Jennifer Alsop, Rosalind Glasspool, Chiu-Chen Tseng, Joy Hendley, Dennis J. Slamon, Jennifer A. Doherty, Andrew Berchuck, Anna H. Wu, Anna M. Piskorz, Chen Wang, Cristina Rodríguez-Antona, D.G.H. de Silva, Valerie Rhenius, Peter A. Fasching, Stacey J. Winham, Gary L. Keeney, Teodora Goranova, Joshy George, Jan Lubinski, Michelle J. Henderson, Rex C. Bentley, Jenny Lester, Sabine Behrens, Joellen M. Schildkraut, Michael E. Carney, Timothy Budden, David G. Huntsman, Oleg Oszurek, Michael S. Anglesio, Jacek Gronwald, Ruby Yun-Ju Huang, Martin Köbel, Javier Benitez, Martin Widschwendter, Melissa C. Larson, Raghwa Sharma, Clara Bodelon, Usha Menon, Janusz Menkiszak, Blake Gilks, María Josefa Mosteiro García, Jesús García-Donas, Wafaa Elatre, Scott H. Kaufmann, Paul Haluska, Pamela J. Thompson, Boris Winterhoff, Susan J. Ramus, Louise A. Brinton, Simon A. Gayther, Mary Anne Rossing, Georgia Chenevix-Trench, Hugh Luk, Jolanta Lissowska, Marc T. Goodman, Billy Chen, Beth Y. Karlan, Naveena Singh, Sian Fereday, Mark E. Sherman, Ana Osorio, Lynne R. Wilkens, Maria P. Intermaggio, Brenda Y. Hernandez, Britton Trabert, Esther Herpel, Mercedes Jimenez-Linan, Janine Senz, Geyi Liu, Celeste Leigh Pearce, Samuel C Y Leong, Iain A. McNeish, Isabelle Ray-Coquard, Susana Banerjee, Malcolm C. Pike, Liz-Anne Lewsley, Helen Steed, Honglin Song, Samantha Hinsley, David D.L. Bowtell, James D. Brenton, Holly R. Harris, Tuan Zea Tan, Cezary Cybulski, Alicia Beeghly-Fadiel, A. Toloczko, Nikilyn Nevins, Robert S. Brown, Darren Ennis, Stephanie Chen, Euan A. Stronach, José Palacios, Sandra Orsulic, Anna deFazio, Geoff Macintyre, Kara L. Cushing-Haugen, Mila Volchek, Aleksandra Gentry-Maharaj, Jenny Chang-Claude, Ellen L. Goode, Paul D.P. Pharoah, Hanwei Sudderuddin, Stefan Kommoss, Derek S. Chiu, Huei San Leong, Peter Sinn, Catherine J. Kennedy, Chloe Karpinskyj, Alison Brand, Amy Lum, Veronica Chow, Nicolas Wentzensen, Tayyebeh M. Nazeran, Nadia Traficante, Dustin Johnson, Yoke-Eng Chiew, Casey S. Greene, Jennifer M Koziak, Renée T. Fortner
Publikováno v:
Clinical Cancer Research. 26:5411-5423
Purpose: Gene expression–based molecular subtypes of high-grade serous tubo-ovarian cancer (HGSOC), demonstrated across multiple studies, may provide improved stratification for molecularly targeted trials. However, evaluation of clinical utility h
Autor:
Yenarae Lee, Andrew D. Cherniack, Ursula A. Matulonis, Kristopher A. Sarosiek, Elizabeth L. Christie, Levi A. Garraway, Maria B. Baco, Ioannis K. Zervantonakis, Weiqun Zhang, Jeremy Ryan, Guo Wei, Federica Piccioni, Joan Montero, Felice J. Liang, Sasha Pantel, Elizabeth H. Stover, Matthew Meyerson, Maya K. Gelbard, Ofir Cohen, Cory M. Johannessen, David D.L. Bowtell, Amy Goodale, Adam G. Presser, Jennifer L. Guerriero, Matthew G. Rees, Mukta Bagul, Anthony Letai, Yvonne Y. Li, Patrick Bhola
Publikováno v:
Mol Cancer Res
High-grade serous ovarian cancer (HGSOC) is often sensitive to initial treatment with platinum and taxane combination chemotherapy, but most patients relapse with chemotherapy-resistant disease. To systematically identify genes modulating chemotherap
1429Impact of BRCA mutation status and lifestyle factors on survival among women with ovarian cancer
Autor:
Kathryn Alsop, David D.L. Bowtell, Andreas Obermair, Peter Grant, Rachel Delahunty, Kate Gersekowski, Susan J. Jordan, Anna deFazio, Ellen L Goode, Michael Friedlander
Publikováno v:
International Journal of Epidemiology. 50
Background Despite their increased risk of developing ovarian cancer, women with an inherited BRCA1 or BRCA2 mutation have been shown to have better survival after diagnosis. Components of a healthy lifestyle, including smoking, physical activity and
Autor:
Andrew J. Colebatch, Anthony T. Papenfuss, Clare G Fedele, Nicholas K. Hayward, Pacman Szeto, Jodie Leditschke, Richard A. Scolyer, Jennifer Mooi, Raymond J. Cho, Athena Hatzimihalis, Daniel L Cameron, Heather Thorne, Jason Ellul, Mitchell P. Levesque, Stephen Cordner, Grant A. McArthur, Noel Woodford, Julia Lai Kwon, Phil F. Cheng, Sarah-Jane Dawson, Reinhard Dummer, Rory Wolfe, Kathryn Alsop, Mark Shackleton, Angela Peng, Daniel S. Widmer, Gisela Mir Arnau, Jeanette Raleigh, Richard J. Young, Valerie C Amann, Ismael A. Vergara, Lachlan McIntosh, Shahneen Sandhu, James S. Wilmott, Xuelin Dou, Stephen Q. Wong, Graham J. Mann, Patricia C. M. O’Brien, Christopher P. Mintoff, David D.L. Bowtell, Samantha E. Boyle
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Although melanoma is initiated by acquisition of point mutations and limited focal copy number alterations in melanocytes-of-origin, the nature of genetic changes that characterise lethal metastatic disease is poorly understood. Here, we analyze the
Autor:
Paul D.P. Pharoah, Alan Herschtal, Anna deFazio, Susan J. Ramus, Ellen L. Goode, Sian Fereday, Flurina Saner, Dale W. Garsed, Ahwan Pandey, Stephanie Lheureux, David D.L. Bowtell, Malcolm C. Pike, Brad H. Nelson, Jessica A. Beach, Andrew Berchuck, Celeste Leigh Pearce
Publikováno v:
Nat Rev Cancer
Research into factors affecting treatment response or survival in patients with cancer frequently involves cohorts that span the most common range of clinical outcomes, as such patients are most readily available for study. However, attention has tur
Autor:
Sally M Hunter, Aocs, David D.L. Bowtell, Simone M Rowley, Ian G. Campbell, Richard Lupat, Maria A. Doyle, Prue E. Allan, Kylie L. Gorringe, Jason Li, Genevieve V. Dall
Publikováno v:
BMC Research Notes
BMC Research Notes, Vol 13, Iss 1, Pp 1-8 (2020)
BMC Research Notes, Vol 13, Iss 1, Pp 1-8 (2020)
Objective Ovarian fibromas and adenofibromas are rare ovarian tumours. They are benign tumours composed of spindle-like stromal cells (pure fibroma) or a mixture of fibroblast and epithelial components (adenofibroma). We have previously shown that 40
Autor:
Kylie L. Gorringe, Jan Pyman, Matthew Wakefield, Cassandra J. Vandenberg, Orla McNally, Jeanne Tie, Gwo-Yaw Ho, David D.L. Bowtell, Clare L. Scott, Sumitra Ananda
High-grade mucinous ovarian cancer (HGMOC) is often a misnomer as the majority of cases are metastatic disease with a gastro-intestinal origin. The standard platinum-based ovarian cancer (OC) chemotherapy regimens are often ineffective, and there are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d75964cad96db47583cae8263019946
https://doi.org/10.5772/intechopen.92554
https://doi.org/10.5772/intechopen.92554
Autor:
Scott H. Kaufmann, Daniel Guimarães Tiezzi, Valerie Rhenius, Gary L. Keeney, Alexander Hein, Dominique-Laurent Couturier, Florin Andrei Taran, Robert Edwards, Aline Talhouk, Stacey J. Winham, Christiani Bisinoto de Sousa, Nadja Pejovic, Andreas D. Hartkopf, Ramona Erber, Brenda Y. Hernandez, Jenny Lester, Teri A. Longacre, Anna L. Paterson, Peter Sinn, Robin Crawford, Lene Lundvall, Hugh Luk, Roberta B. Ness, Adekunle Odunsi, Suha Deen, Javier Benitez, Alice S. Whittemore, Anna Fischer, Anthony N. Karnezis, Christine Chow, Ana Osorio, Ellen L. Goode, Stefan Kommoss, Angela Brooks-Wilson, Linda E. Kelemen, Tanja Pejovic, Simon A. Gayther, Peter A. Fasching, Beth Y. Karlan, Jurandyr Moreira de Andrade, Samuel Leung, David D.L. Bowtell, James D. Brenton, Aleksandra Vrvilo, Marc T. Goodman, Paul D.P. Pharoah, Sara Y. Brucker, Honglin Song, Jennifer M Koziak, Robert A. Vierkant, Naveena Singh, Valerie McGuire, Chloe Karpinskyj, Mercedes Jimenez-Linan, Aleksandra Gentry-Maharaj, Anna deFazio, Jenny Chang-Claude, Linda S. Cook, Francesmary Modugno, Filipe C. Martins, Estrid Høgdall, Prafull Ghatage, Marie Lyne Alcaraz, Susan J. Ramus, Annette Staebler, Jennifer Alsop, David G. Huntsman, Joseph H. Rothstein, Tayyebeh M. Nazeran, Cristina Rodríguez-Antona, Luis Robles-Díaz, Bryan M. McCauley, María Jesús Gómez García, Michael E. Carney, Michael S. Anglesio, Yurii B. Shvetsov, Claus Høgdall, Sian Fereday, Martin Köbel, Maria P. Intermaggio, Sandra Orsulic, Luis Paz-Ares, Mary Anne Brett, Weiva Sieh, Matthias W. Beckmann, Helen Steed, Arndt Hartmann, Michael Schneider, Lynne R. Wilkens, Esther Herpel, Jacek Gronwald, Francisco José Candido dos Reis, Nhu D. Le, Gregg Nelson, Kirsten B. Moysich, Nadia Traficante, Usha Menon
Publikováno v:
British journal of cancer, vol 123, iss 5
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Martins, F C, Couturier, D, Paterson, A, Karnezis, A N, Chow, C, Nazeran, T M, Odunsi, A, Gentry-maharaj, A, Vrvilo, A, Hein, A, Talhouk, A, Osorio, A, Hartkopf, A D, Brooks-wilson, A, Defazio, A, Fischer, A, Hartmann, A, Hernandez, B Y, Mccauley, B M, Karpinskyj, C, De Sousa, C B, Høgdall, C, Tiezzi, D G, Herpel, E, Taran, F A, Modugno, F, Keeney, G, Nelson, G, Steed, H, Song, H, Luk, H, Benitez, J, Alsop, J, Koziak, J M, Lester, J, Rothstein, J H, De Andrade, J M, Lundvall, L, Paz-ares, L, Robles-díaz, L, Wilkens, L R, Garcia, M J, Intermaggio, M P, Alcaraz, M, Brett, M A, Beckmann, M W, Jimenez-linan, M, Anglesio, M, Carney, M E, Schneider, M, Traficante, N, Pejovic, N, Singh, N, Le, N, Sinn, P, Ghatage, P, Erber, R, Edwards, R, Vierkant, R, Ness, R B, Leung, S, Orsulic, S, Brucker, S Y, Kaufmann, S H, Fereday, S, Gayther, S, Winham, S J, Kommoss, S, Pejovic, T, Longacre, T A, Mcguire, V, Rhenius, V, Sieh, W, Shvetsov, Y B, Whittemore, A S, Staebler, A, Karlan, B Y, Rodriguez-antona, C, Bowtell, D D, Goode, E L, Høgdall, E, Candido Dos Reis, F J, Gronwald, J, Chang-claude, J, Moysich, K B, Kelemen, L E, Cook, L S, Goodman, M T, Fasching, P A, Crawford, R, Deen, S, Menon, U, Huntsman, D G, Köbel, M, Ramus, S J, Pharoah, P D P & Brenton, J D 2020, ' Clinical and pathological associations of PTEN expression in ovarian cancer : a multicentre study from the Ovarian Tumour Tissue Analysis Consortium ', British Journal of Cancer, vol. 123, no. 5, pp. 793-802 . https://doi.org/10.1038/s41416-020-0900-0
British Journal of Cancer
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Martins, F C, Couturier, D, Paterson, A, Karnezis, A N, Chow, C, Nazeran, T M, Odunsi, A, Gentry-maharaj, A, Vrvilo, A, Hein, A, Talhouk, A, Osorio, A, Hartkopf, A D, Brooks-wilson, A, Defazio, A, Fischer, A, Hartmann, A, Hernandez, B Y, Mccauley, B M, Karpinskyj, C, De Sousa, C B, Høgdall, C, Tiezzi, D G, Herpel, E, Taran, F A, Modugno, F, Keeney, G, Nelson, G, Steed, H, Song, H, Luk, H, Benitez, J, Alsop, J, Koziak, J M, Lester, J, Rothstein, J H, De Andrade, J M, Lundvall, L, Paz-ares, L, Robles-díaz, L, Wilkens, L R, Garcia, M J, Intermaggio, M P, Alcaraz, M, Brett, M A, Beckmann, M W, Jimenez-linan, M, Anglesio, M, Carney, M E, Schneider, M, Traficante, N, Pejovic, N, Singh, N, Le, N, Sinn, P, Ghatage, P, Erber, R, Edwards, R, Vierkant, R, Ness, R B, Leung, S, Orsulic, S, Brucker, S Y, Kaufmann, S H, Fereday, S, Gayther, S, Winham, S J, Kommoss, S, Pejovic, T, Longacre, T A, Mcguire, V, Rhenius, V, Sieh, W, Shvetsov, Y B, Whittemore, A S, Staebler, A, Karlan, B Y, Rodriguez-antona, C, Bowtell, D D, Goode, E L, Høgdall, E, Candido Dos Reis, F J, Gronwald, J, Chang-claude, J, Moysich, K B, Kelemen, L E, Cook, L S, Goodman, M T, Fasching, P A, Crawford, R, Deen, S, Menon, U, Huntsman, D G, Köbel, M, Ramus, S J, Pharoah, P D P & Brenton, J D 2020, ' Clinical and pathological associations of PTEN expression in ovarian cancer : a multicentre study from the Ovarian Tumour Tissue Analysis Consortium ', British Journal of Cancer, vol. 123, no. 5, pp. 793-802 . https://doi.org/10.1038/s41416-020-0900-0
British Journal of Cancer
Background PTEN loss is a putative driver in histotypes of ovarian cancer (high-grade serous (HGSOC), endometrioid (ENOC), clear cell (CCOC), mucinous (MOC), low-grade serous (LGSOC)). We aimed to characterise PTEN expression as a biomarker in epithe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13264fefe2a6be09d6a938187ba510f0