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pro vyhledávání: '"929"'
Autor:
Haydn T. Kissick, Maria Cardenas, Jennifer W Carlisle, Adeboye O. Osunkoya, Caroline S. Jansen, Viraj A. Master, Patrick Mullane, Mehmet Asim Bilen, Rachel Greenwald, Ewelina Sobierajska, Nataliya Prokhnevska
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundTumor infiltrating T-cells have a prognostic benefit in many tumor types,1–8 and we recently sought to determine whether the level of T-cell infiltration into renal tumors predicts clinical outcomes. In our recent publication,9 we showed
Autor:
Jinsuk Kang
Publikováno v:
Cancer Research. 81:929-929
STAT3 functions are largely bifurcated: (1) STAT3 activated by Y705 phosphorylation (pY705) regulates target-gene expression in nucleus. (2) STAT3 activated by S727 phosphorylation (pS727) supports a electron transport complex (ETC) in mitochondria.
Autor:
Oscar Arrieta, R. Bernabé, Judith Dalmau, Miguel Angel Molina-Vila, Jorge Carrillo, Remedios Blanco, Teresa Moran, Clara Mayo de las Casas, Jillian Wilhelmina Paulina Bracht, Bonaventura Clotet, Christian Brander, Jordi Argilaguet, Julia G. Prado, Mariano Provencio, Javier Garcia-Corbacho, Ana Giménez-Capitán, Mónica Garzón, Erika Aldeguer, Andrés F. Cardona, Rafael Rosell, Bartomeu Massuti, Javier de Castro, Maria Gonzalez-Cao, Javier Martinez-Picado, Andreas Meyerhans, Sonia Rodríguez, Oscar Juan, Ana Drozdowskyj, Chung-Ying Huang, J. Blanco
Publikováno v:
Cancer Research. 80:929-929
Introduction: Treatment with anti PD-1/PD-L1 antibodies has demonstrated clinical activity in different types of solid tumors, but only 20 to 30% of patients (pts) respond to these immune checkpoint inhibitors (ICIs). Therefore, predictive biomarkers
Akademický článek
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Akademický článek
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Autor:
Carol Thach, Jeff Kucharski, Jingchuan Zhang, Yvonne Yao, Shuangwei Li, Anjali Babbar, Dashyant Dhanak, Rasmus Hansen, Yuan Liu, Yuching Chen, Pingda Ren, Ulf Peters, Yi Liu, Shisheng Li, Ke Yu, Yi Wang, Patrick Parvis Zarrinkar, Xiaohu Deng, Matthew R. Janes, Sarah J. Firdaus, Ata Zarieh, Lian-Sheng Li, Tao Wu, Xin Guo, Jun Feng, Matthew V. Lorenzi, Dana D. Hu-Lowe, Jeffrey H. Chen
Publikováno v:
Cancer Research. 78:929-929
Activating mutations in KRAS have a high prevalence in human cancer. The codon 12 glycine to cysteine missense mutation (KRASG12C) is among the most common KRAS mutations, present in non-small cell lung adenocarcinoma (~15 %), colorectal adenocarcino
Autor:
Max S. Wicha, Michael D. Brooks
Publikováno v:
Cancer Research. 77:929-929
The CSC hypothesis posits that there is a subset of tumors cells driving tumor growth and metastasis and that by targeting this population, tumors can be more efficiently eradicated. Recently it was shown that there are two types of CSCs in breast ca
Publikováno v:
Annals of surgery. 247(1)
To identify risk factors associated with cancer-specific survival and develop a predictive model for patients undergoing primary hepatic resection for metastatic colorectal cancer.No published studies investigated collectively the inter-relation of f
Autor:
Timothy P. Kuka, Jason B. Bell, Branden S. Moriarity, Vincent W. Keng, David A. Largaespada, Barbara R. Tschida
Publikováno v:
Cancer Research. 74:929-929
The role of zinc finger and BTB domain containing 20 (ZBTB20) in hepatocellular carcinoma (HCC) is not well defined, as there are many discrepancies in the literature regarding its role in liver tumorigenesis. ZBTB20 has been implicated to play a rol
Autor:
K. Yahara
Publikováno v:
Radiotherapy and Oncology. 99:S356-S357