Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Jeremy N. Rich"'
Autor:
Briana C. Prager, Kristopher Berrett, Jeremy N. Rich, Michael N. Wilkinson, Joshua B. Rubin, Sumithra Sankararaman, Lauren Broestl, Xuhua Chen, Robi D. Mitra, Zongtai Qi, Najla Kfoury, Jason Gertz, Arnav Moudgil
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Consistent sex differences in incidence and outcome have been reported in numerous cancers including brain tumors. GBM, the most common and aggressive primary brain tumor, occurs with higher incidence and shorter survival in males compar
Autor:
Tomoyuki Koga, Jianfang Ning, Jun Ma, Anhua Wu, Clark C. Chen, Beibei Xu, Tao Jiang, Gan You, Megan M. Kaneda, Frank B. Furnari, Judith A. Varner, Kunal S. Patel, Ryan M. Shepard, Jeremy N. Rich, Sanjay Dhawan, Ming Li, Andrew S. Venteicher, Aaron L. Sarver, Jie Li, Hua Zhu, Christopher K. Glass
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 118, iss 16
Proc Natl Acad Sci U S A
Proc Natl Acad Sci U S A
Precision medicine in oncology leverages clinical observations of exceptional response. Toward an understanding of the molecular features that define this response, we applied an integrated, multiplatform analysis of RNA profiles derived from clinica
Publikováno v:
Genes & Development. 33:591-609
Glioblastoma ranks among the most lethal of all human cancers. Glioblastomas display striking cellular heterogeneity, with stem-like glioblastoma stem cells (GSCs) at the apex. Although the original identification of GSCs dates back more than a decad
Autor:
Tong Hu, Luciano Mazzoccoli, Jeremy N. Rich, Sachendra S. Bais, Michael S. Diamond, Milan G. Chheda, Hideho Okada, Pei Yong Shi, Arijita Jash, Jennifer Govero, Camila R. Fontes-Garfias, Sujan Shresta, Sharmila Nair, Chao Shan
Publikováno v:
JCI insight, vol 6, iss 1
JCI Insight, Vol 6, Iss 1 (2021)
JCI Insight
JCI Insight, Vol 6, Iss 1 (2021)
JCI Insight
Glioblastoma multiforme (GBM) is a fatal human cancer in part because GBM stem cells are resistant to therapy and recurrence is inevitable. Previously, we demonstrated Zika virus (ZIKV) targets GBM stem cells and prevents death of mice with gliomas.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a70a1ddc1d5cb1ac10ad87cd9a425e2b
https://escholarship.org/uc/item/00x665sr
https://escholarship.org/uc/item/00x665sr
Autor:
Jacob Schimelman, Tyler E. Miller, Benjamin F. Cravatt, Alysson R. Muotri, Shruti Bhargava, Zheng Zhong, Deobrat Dixit, Derrick Lee, Shaochen Chen, Xueyi Wan, Bingjie Sun, Michael H. Lorenzini, Qi Xie, Jing Tian, Aaron Yu, Jeremy N. Rich, Reilly L. Kidwell, Zhixin Qiu, Linjie Zhao, Ryan C. Gimple, Hui Jing, Briana C. Prager, Zhe Zhu, Jing Tang, Pengrui Wang, Pinar Mesci, Min Tang, Trevor Tam, Qiulian Wu
Publikováno v:
Cell Research
Cell research, vol 30, iss 10
Cell research, vol 30, iss 10
Brain tumors are dynamic complex ecosystems with multiple cell types. To model the brain tumor microenvironment in a reproducible and scalable system, we developed a rapid three-dimensional (3D) bioprinting method to construct clinically relevant bio
Autor:
Amber Kerstetter-Fogle, Eckhard Jankowsky, Andrew E. Sloan, Harry Hoffman, Anirban Sen Gupta, Ansh Desai, Jill S. Barnholtz-Sloan, Anthony Sloan, Jeremy N. Rich, Theresa Elder, Peggy L.R. Harris, Christine Lee-Poturalski, Gino Cioffi
Publikováno v:
Neuro-Oncology. 23:vi24-vi24
The effect of platelets on oncogenesis has been studied extensively in cancer metastasis, but not in glioblastoma (GBM), where metastasis is rare. Here we identify the unique crosstalk between glioma stem cells (GSCs) and platelets within GBM solid t
Autor:
Brett M. Stevens, Daniel A. Pollyea, Shanshan Pei, Jason R. Myers, Anagha Inguva, Craig T. Jordan, John M. Ashton, Tobias Neff, Stephen C. Mack, Clayton A. Smith, Hyunmin Kim, Kevin Shannon, Nabilah Khan, Jeremy N. Rich, Mohammad Minhajuddin, Aik Choon Tan, Sisi Lai, Biniam Adane
Publikováno v:
Cell stem cell, vol 23, iss 1
Leukemia stem cells (LSCs) are thought to drive the genesis of acute myeloid leukemia (AML) as well as relapse following chemotherapy. Because of their unique biology, developing effective methods to eradicate LSCs has been a significant challenge. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27071f0283097248d78f38e0dbe1a23a
https://escholarship.org/uc/item/40b9w7gg
https://escholarship.org/uc/item/40b9w7gg
Publikováno v:
Biochemical and Biophysical Research Communications. 406:643-648
Glioblastomas (GBMs) are the most lethal and common types of primary brain tumors. The hallmark of GBMs is their highly infiltrative nature. The cellular and molecular mechanisms underlying the aggressive cancer invasion in GBMs are poorly understood
Publikováno v:
Biochemical Pharmacology. 80:654-665
Glioblastoma is the most common and lethal type of primary brain tumor. Despite recent therapeutic advances in other cancers, the treatment of glioblastomas remains ineffective and essentially palliative. The treatment failure is a result of a number
Autor:
Sisi Lai, Xun Jin, Leo J.Y. Kim, Jeremy N. Rich, Lisa C. Wallace, Tanwarat Sanvoranart, Deobrat Dixit, Qiulian Wu
Publikováno v:
Neuro-Oncology. 19:vi227-vi227
Post-transcriptional regulation of gene expression is well-controlled across normal tissues. Dysregulation of these regulatory events contributes to tumorigenesis and progression of cancer. RNA binding proteins (RBPs), as trans-acting factors, play a