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Publikováno v:
International Immunopharmacology. 17:576-584
Background The prevalence of food allergy has increased dramatically during the last three decades, but currently there was no effective therapy except avoidance of allergen. This study aimed to investigate the effect of a modified Chinese herbal for
Autor:
Henrik Wie, Eva Imislund Beck
Publikováno v:
Acta Pharmacologica et Toxicologica. 48:294-299
The metabolism of collagen and mineral was studied during a nine-day postmedicational period in young, male rats receiving high-dose intraperitoneal cyclophosphamide treatment every second day for 12 days. Two days after ending medication the white b
Publikováno v:
Acta Pharmacologica et Toxicologica. 50:175-184
In isolated detrusor from guinea-pigs and rats substance P (SP) induced concentration-dependent phasic contractions. Rabbit detrusor strips responded to SP with an initial phasic and an ensuing tonic contraction. The concentration-response curve to S
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. :1-7
The effect of 8-bromocyclic AMP (8-Br-cAMP) and phorbol 12-myristate 13-acetate (PMA), a protein kinase C activator, on cytosolic free calcium concentration ([Ca2+]i) in normal rat anterior pituitary cells was examined. [Ca2+]i was monitored directly
Autor:
Clemens Gillen, Peter Illes, Mahmoud Al-Khrasani, Sebestyen J. Borvendeg, Patrizia Rubini, Herbert M. Himmel, Wolfgang Fischer, Kerstin Wirkner, Clemens Allgaier
Publikováno v:
European Journal of Pharmacology. 474:71-75
The application of cyclophosphamide to rats was used to induce interstitial cystitis. Behavioural studies indicated a strong pain reaction that developed within 2 h and levelled off thereafter causing a constant pain during the following 18 h. Neuron
Publikováno v:
Steroids. 64:726-734
Results from our lab have shown previously that parathyroid hormone (PTH) is not the key factor in the rapid regulation of plasma Ca2+. The possible role of 1,25(OH)2D3 in the rapid minute-to-minute regulation of plasma Ca2+, as addressed by a possib
Publikováno v:
European Journal of Pharmacology. 297:71-76
We investigated the effect of hypercholesterolemia on the vascular reactivity of thoracic aortas isolated from hypertensive Dahl salt-sensitive (DS) rats. DS rats were fed on a low-sodium diet (control group), a low-sodium plus high-cholesterol diet
Publikováno v:
Fitoterapia. 82(7)
Imperatorin (Imp) as a hypotensive active ingredient, its hypotensive effect was evaluated in the SHRs, its calcium antagonism and affinity to L-type calcium channel was also confirmed. The results showed that the blood pressure was decreased in the
Publikováno v:
Agents and Actions. 40:28-36
The mechanisms of vancomycin (VCM)-induced histamine release were studied with rat peritoneal mast cells. VCM (1 x 10(-3) M) released histamine from the isolated mast cells in a dose-dependent and noncytotoxic manner. In the absence of extracellular
Autor:
Renzo Levi, Amandine Fitou, Alessia Brero, Roberta Ramella, Giuseppe Alloatti, Maria Pia Gallo, Claudio Dati
Publikováno v:
Cardiovascular research. 88(3)
Aims The ErbB–neuregulin-1β1 (Nrg1β1) pathway is required for cardiac development and exerts chronic effects on the postnatal adult heart. Long-term application of Nrg1β1 results in hypertrophy and protection against oxidative stress and cytotox