Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Yong J. Lee"'
Publikováno v:
Cancer Medicine
Cancer Medicine, Vol 9, Iss 5, Pp 1753-1767 (2020)
Cancer Medicine, Vol 9, Iss 5, Pp 1753-1767 (2020)
Molecular‐targeted therapies have demonstrated disappointing results against most advanced solid cancers. This may largey be attributed to irrational drug use against unselected cancers. We investigated the efficacy of dual MEK‐PI3K drug therapy
Publikováno v:
Orphanet Journal of Rare Diseases
Orphanet Journal of Rare Diseases, Vol 15, Iss 1, Pp 1-13 (2020)
Orphanet Journal of Rare Diseases, Vol 15, Iss 1, Pp 1-13 (2020)
Background Mucinous colon cancers (MCC) are characterized by abundant production of mucin 2 (MUC2) protein and are less sensitive to standard systemic chemotherapy. We postulated that severe/persistent endoplasmic reticulum stress (ERS) aggravation i
Autor:
Lesley M. Foley, Hima Makala, Haroon A. Choudry, Robin Frederick, Ashok K. Dilly, Jianxia Guo, David L. Bartlett, Jan H. Beumer, T. Kevin Hitchens, Yong J. Lee, Brendon D. Honick, Anuleka Elapavaluru, Lora H. Rigatti, Sachin Velankar
Publikováno v:
Transl Res
Abundant intraperitoneal (IP) accumulation of extracellular mucus in patients with appendiceal mucinous carcinoma peritonei (MCP) causes compressive organ dysfunction and prevents delivery of chemotherapeutic drugs to cancer cells. We hypothesized th
Autor:
Yong J. Lee
Publikováno v:
Cancer Research. 80:1239-1239
Ferroptosis has been reported as a unique form of cell death. However, in recent years, researchers have increasingly challenged the uniqueness of ferroptosis compared to other types of cell death. In this study, we examined whether ferroptosis share
Autor:
Eun Kyung Lee, Seul Gi Yoon, Chang Sik Choi, Hanho Shin, Dong H. Son, Jung Hyuck Park, Ki Woo Kim, Jung Eun Kim, Jun Gi Rho, Wook Kim, Ji H. Han, Juhwan Yoon, Je K. Seong, Il Yong Kim, Byung Joo Song, Yong J. Lee
Publikováno v:
Diabetes, obesitymetabolism. 20(9)
Aim To analyze the metabolic parameters and adipose tissue inflammation via NLRP3 inflammasome following chronic treatment of mouse models of obesity with AJ5018 as the peripherally restricted cannabinoid 1 receptor (CB1R) antagonist. Materials and m
Autor:
Herbert J. Zeh, Yong J. Lee, Haroon A. Choudry, Brendon D. Honick, Z S Guo, David L. Bartlett, Ashok K. Dilly
Publikováno v:
Oncotarget
// Ashok K. Dilly 1 , Brendon D. Honick 1 , Yong J. Lee 1, 2 , Zong S. Guo 1 , Herbert J. Zeh 1 , David L. Bartlett 1 and Haroon A. Choudry 1 1 Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh PA 15232, USA 2 Department of P
Autor:
Soyeun Park, Yong J. Lee
Publikováno v:
New Physics: Sae Mulli. 65:328-332
Autor:
Marco A. Alcala, Jinsang Yoo, David L. Bartlett, Byeong-Chel Lee, Bae-Hang Park, Dae Hee Lee, Kyung Soo Park, Yong J. Lee
Publikováno v:
Journal of Cellular Biochemistry. 110:1073-1081
Approximately 25% of patients with colorectal cancer develop metastases to the liver, and surgery is currently the best treatment available. But there are several patients who are unresectable, and isolated hepatic perfusion (IHP) offers a different
Publikováno v:
International Journal of Hyperthermia. 22:713-728
This study investigated whether hyperthermia can enhance TRAIL-induced apoptotic death.Human prostate adenocarcinoma DU-145, human pancreatic carcinoma MIA PaCa-2 and BxPC-3, human colon fibroblast CCD-33Co and rat prostate endothelial YPEN-1 cells w
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 51:785-790
Purpose: Combined use of 13- cis -retinoic acid (cRA) and interferon-α2a (IFNα) induced significant radiosensitization in human cervical cancer ME-180 cell line, whereas it failed to achieve similar radiation enhancement in HeLa cells. The differen