Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Stephan D. Voss"'
Autor:
Jasmine Lin, William G. Kaelin, Katherine A. Janeway, Ari J. Wassner, Brent R. Weil, Sara O. Vargas, Steven G. DuBois, Jill A. Madden, Junne Kamihara, Kayla V. Hamilton, Stephan D. Voss, Rodolfo F. Perini, Matthew M. Heeney, Naseem J. Zojwalla, Alma Imamovic, Jessica A. Pollard, Catherine B. Wall, Catherine Clinton
Publikováno v:
New England Journal of Medicine. 385:2059-2065
The integration of genomic testing into clinical care enables the use of individualized approaches to the management of rare diseases. We describe the use of belzutifan, a potent and selective small-molecule inhibitor of the protein hypoxia-inducible
Autor:
Brenda J. Weigel, Keith D. Wilner, David Hall, Charles G. Minard, Jennifer Foster, Peter C. Adamson, Stacey L. Berg, Elizabeth Fox, Susan M. Blaney, Stephan D. Voss, Yael P. Mosse, Frank M. Balis
Publikováno v:
Clinical Cancer Research. 27:3543-3548
Purpose: Anaplastic lymphoma kinase (ALK) aberrations are a promising target for patients with neuroblastoma. We assessed the activity of first-generation ALK inhibitor crizotinib in patients with no known curative treatments and whose tumors harbore
Autor:
Steven G. DuBois, Stephan A. Grupp, John J. Doski, Daphne A. Haas-Kogan, Julie R. Park, Lisa Diller, Geetika Khanna, Steve Braunstein, Susan G. Kreissman, Wendy B. London, Stephan D. Voss, Arlene Naranjo, Kevin X. Liu, Fan F Zhang, James D. Geiger
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, vol 38, iss 24
J Clin Oncol
J Clin Oncol
PURPOSE A primary objective of the Children’s Oncology Group (COG) ANBL0532 phase III study was to assess the effect of increasing local dose of radiation to a residual primary tumor on the cumulative incidence of local progression (CILP) in patien
Publikováno v:
Pediatric Radiology. 50:1602-1609
Neck computed tomography (CT) angiography is commonly ordered for pediatric patients with soft palate trauma to exclude vascular injury. Debate exists regarding what type of imaging is indicated in this setting, particularly amid growing concern that
Autor:
Stacey L. Berg, Kara L. Davis, Brenda J. Weigel, Charles G. Minard, Crystal L. Mackall, Elizabeth Fox, Rachel A. Kudgus, Stephan D. Voss, Melinda S. Merchant, Joel M. Reid, Xiaowei Liu
Publikováno v:
Lancet Oncol
Summary Background Immune checkpoint inhibitors targeting PD-1 have shown clinical benefit in adults with cancer, but data on these drugs in children are scarce. We did a phase 1–2 study of nivolumab, a PD-1 blocking monoclonal antibody, to determi
Autor:
Elizabeth Fox, Sharmistha Pal, Rachel A. Kudgus, Kristina A. Cole, Stephan D. Voss, Brenda J. Weigel, Daphne A. Haas-Kogan, Bruce R. Pawel, Stacey L. Berg, John M. Maris, Xiaowei Liu, Joel M. Reid, Charles G. Minard, Heba Ijaz
Publikováno v:
Clinical Cancer Research. 26:1213-1219
Purpose: Adavosertib (AZD1775), an inhibitor of WEE1 kinase, potentiates replicative stress induced by oncogenes or chemotherapy. Antitumor activity of adavosertib has been demonstrated in preclinical models of pediatric cancer. This phase I trial wa
Autor:
Stephan D. Voss
Publikováno v:
Pediatric Radiology. 49:1534-1544
Functional imaging techniques are playing an increasingly important role in the management of pediatric cancer. Technological advances have pushed the development of hybrid imaging techniques, including positron emission tomography (PET)/CT, PET/MR a
Autor:
Mitchell S. Cairo, Stephan D. Voss
Publikováno v:
Pediatric Radiology. 49:1565-1573
Current therapies used in treating children with Hodgkin lymphoma and many histological subtypes of non-Hodgkin lymphoma have resulted in overall survival rates exceeding 90% in many instances. With increasing concerns related to the cost of radiolog
Autor:
Ronan Sugrue, A. Lindsay Frazier, Marc R. Laufer, Brynn E. Marks, Laurie E. Cohen, Wallace Bourgeois, Catherine M. Gordon, Stephan D. Voss
Publikováno v:
Journal of the Endocrine Society
Introduction GNAS mutations have been reported in both McCune-Albright syndrome (MAS) and juvenile granulosa cell tumors (JGCT) but have never been reported simultaneously in the same patient. Case Presentation A 15-year-old girl developed secondary
Autor:
Thomas Ng, Niharika Putta, Samuel Nurko, Rachel Rosen, Neha Kwatra, Laura A. Drubach, Alejandro Flores, Stephan D. Voss, Frederic H. Fahey
Publikováno v:
The American journal of gastroenterology. 116(7)