Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Simon Peter Williams"'
Autor:
Alex de Crespigny, Paul E. Christian, Sandra Sanabria Bohorquez, Lance D. Burrell, Andrei Iagaru, Paulo Castaneda, Justin Albiani, Nicholas Sandella, John M. Hoffman, Simon-Peter Williams
Publikováno v:
Journal of Nuclear Medicine Technology. 48:54-57
Objective: To harmonize multicenter 89Zr PET imaging for oncology trials and to evaluate lesion detection. Methods: Seven PET scanners were evaluated using a custom chest oncology phantom with nine spherical lesions, 7-20 mm in diameter. A 4:1 lesion
Autor:
Judith E. Flores, Jan Marik, Anton G.T. Terwisscha van Scheltinga, Ron Firestein, Shang-Fan Yu, Weiguang Mao, Mary Ann Go, Jeffrey Lau, Alexander N. Vanderbilt, Li Miao, Annie Ogasawara, David Kan, Jeff N. Tinianow, Simon-Peter Williams, Joshua Goldsmith, Bonnee Rubinfeld, Herman Gill
Publikováno v:
Oncotarget, 7(18), 25103-25112. Impact Journals LLC
Oncotarget
Oncotarget
// Simon-Peter Williams 1 , Annie Ogasawara 1 , Jeff N. Tinianow 1 , Judith E. Flores 1 , David Kan 1 , Jeffrey Lau 1 , MaryAnn Go 1 , Alexander N. Vanderbilt 1 , Herman S. Gill 1 , Li Miao 1 , Joshua Goldsmith 1 , Bonnee Rubinfeld 1 , Weiguang Mao 1
Publikováno v:
Drug discovery today. Technologies. 8(2-4)
Molecular imaging is becoming an indispensable part of clinical drug development. The presented review highlights few state-of-the-art examples that serve to illustrate specific points and discuss future directions of the use of positron emission tom
Publikováno v:
Biochemical Society Transactions. 23:376-381
Autor:
Judith E Flores-Mercado, Fei Su, Klaus P. Hoeflich, Taner Dogan, Nicholas van Bruggen, Andreas R Baudy, Simon-Peter Williams
Publikováno v:
EJNMMI Research
Background The BRAF inhibitor, vemurafenib, has recently been approved for the treatment of metastatic melanoma in patients harboring BRAFV600 mutations. Currently, dual BRAF and MEK inhibition are ongoing in clinical trials with the goal of overcomi
Publikováno v:
EJNMMI Research
Background A retrospective analysis of estimates of tumor glucose uptake from 1,192 dynamic 2-deoxy-2-(18F)fluoro-D-glucose-positron-emission tomography [FDG-PET] scans showed strong correlations between blood glucose and both the uptake rate constan
Publikováno v:
Biochemical Society Transactions. 19:997-1001
Autor:
Lisa J. Bernstein, Napoleone Ferrara, Frank J. Giordano, Hans-Peter Gerber, Simon-Peter Williams, Nicholas van Bruggen, Kenneth R. Chien, Stuart Bunting, Franklin Peale
Publikováno v:
Journal of magnetic resonance imaging : JMRI. 14(4)
A mouse model of non-necrotic vascular deficiency in the adult heart was studied using cine-magnetic resonance imaging (MRI) and other techniques. The mice lacked cardiomyocyte-derived vascular endothelial growth factor (VEGF) following a targeted kn
Autor:
Nicholas F. Paoni, Fay Wang, Gianfranco de Feo, Wei Li, Tarif Awad, Hongkui Jin, Brian Shimada, Simon-Peter Williams, Renhui Yang, Annie Ogasawara, P. Mickey Williams
Publikováno v:
Circulation. 103(5)
Background —ACE inhibition after myocardial infarction (MI) has been shown to have beneficial effects on cardiac anatomy and function. The purpose of this study was to examine the effects of ACE inhibition on cardiac gene expression after MI. Metho
Autor:
Napoleone Ferrara, Belinda Cairns, Harold Thibodeaux, Nicholas van Bruggen, Wyne P. Lee, Ling Fu, Daniel Tumas, Robert Gerlai, Menno van Lookeren Campagne, James T. Palmer, Simon-Peter Williams
Publikováno v:
The Journal of clinical investigation. 104(11)
VEGF is mitogenic, angiogenic, and a potent mediator of vascular permeability. VEGF causes extravasation of plasma protein in skin bioassays and increases hydraulic conductivity in isolated perfused microvessels. Reduced tissue oxygen tension trigger