Zobrazeno 1 - 10
of 158
pro vyhledávání: '"Robert Zeiser"'
Autor:
Robert Zeiser, Takanori Teshima
Publikováno v:
Blood. 138:2165-2172
Acute graft-versus-host disease (GVHD) is a major life-threatening complication after allogeneic hematopoietic cell transplantation (allo-HCT). The classical target organs of acute GVHD include the intestines, liver, and skin. The damage of these org
Autor:
Meike Burger, Sven Diederichs, Markus G. Manz, Dominik von Elverfeldt, Sanaz Taromi, Mirjam Elze, Annette Schmitt-Graeff, Alicia Schumacher, Bernward Passlick, Bernd Kammerer, Xuekai Zhu, Anna Verena Frey, Justus Duyster, Simon Lagies, Alexander Simonis, Elke Firat, Robert Zeiser, Gabriele Niedermann, Petya Apostolova, Marie Follo, Katrin Schmittlutz, Lukas Braun
Publikováno v:
Cancer Letters. 520:385-399
Metastatic small cell lung cancer (SCLC) is not curable. While SCLC is initially sensitive to chemotherapy, remissions are short-lived. The relapse is induced by chemotherapy-selected tumor stem cells, which express the AC133 epitope of the CD133 ste
Autor:
Gabriele Ihorst, Justus Duyster, Robert Zeiser, Tim Struessmann, Reinhard Marks, Sophie Ewald, Jürgen Finke, Monika Engelhardt, Miguel Waterhouse, Jesus Duque-Afonso, Joachim Müller-Quernheim, Ralph Wäsch, Hartmut Bertz
Publikováno v:
Blood Advances. 5:4327-4337
High-dose chemotherapy, followed by autologous hematopoietic stem cell transplantation (auto-HSCT), is an established therapy for patients with hematological malignancies. The age of patients undergoing auto-HSCT and, therefore, the comorbidities, ha
Autor:
Máté Krausz, Justus Duyster, Bodo Grimbacher, Geoffroy Andrieux, Robert Zeiser, Stefan F. Martin, Franziska M. Uhl, Dietmar Pfeifer, Barbara Sauer, Natalie Köhler, Eileen Haring, Konrad Aumann, Annette Schmitt-Graeff, Petya Apostolova, Philipp R. Esser, Melanie Boerries, Michele Proietti
Publikováno v:
Haematologica. 107:1538-1554
Acute graft-versus-host disease (GvHD) is a life-threatening complication of allogeneic hematopoietic cell transplantation (allo-HCT), a potentially curative treatment for leukemia. Endoplasmic reticulum (ER) stress occurs when the protein folding ca
Autor:
Hartmut Bertz, Henning Schäfer, Reinhard Marks, Jacqueline Blümel-Lehmann, Robert Zeiser, Ralph Wäsch, Jürgen Finke, Gabriele Ihorst
Publikováno v:
Annals of Hematology
We report a single-center phase I/II trial exploring the combination of everolimus (EVE) and mycophenolate mofetil (MMF) as calcineurin inhibitor (CNI)-free GVHD prophylaxis for 24 patients with hematologic malignancies and indication for allogeneic
Autor:
Robert Zeiser, Gabriele Ihorst, Kristina Maas-Bauer, Petya Apostolova, Jürgen Finke, Ralph Wäsch, Hartmut Bertz, Chrissoula Kiote-Schmidt
Publikováno v:
Bone Marrow Transplantation. 56:909-916
Glucocorticoid-refractory (SR) chronic (c) graft-versus-host disease (GVHD) is a multisystem immunological disease and the leading cause of non-relapse mortality (NRM) in patients surviving longer than 2 years after allogeneic hematopoietic cell tran
Autor:
Jesus Duque-Afonso, Gabriele Ihorst, Monika Engelhardt, Robert Zeiser, Reinhard Marks, Khalid Shoumariyeh, Christine Greil, Hartmut Bertz, Justus Duyster, Jürgen Finke, Ralph Wäsch
Publikováno v:
Bone Marrow Transplantation
Allogeneic stem cell transplantation (allo-SCT) offers a curative option in adult patients with acute lymphoblastic leukemia (ALL). Prognostic factors for survival after allo-SCT have not been sufficiently defined: pheno-/genotype, patients´ age, co
Autor:
Toni Cathomen, Philipp Wolf, Sanaz Taromi, Wolfgang W. A. Schamel, Maximilian Seidl, Hinrich Abken, Niko Thorausch, Jamal Alzubi, Robert Zeiser, Johannes Kuehle, Viviane Dettmer-Monaco
Publikováno v:
Molecular Therapy: Oncolytics, Vol 18, Iss, Pp 226-235 (2020)
Molecular Therapy Oncolytics
Molecular Therapy Oncolytics
While chimeric antigen receptor (CAR) T cell immunotherapy targeting CD19 has shown remarkable success in patients with lymphoid malignancies, the potency of CAR T cells in solid tumors is low so far. To improve the efficacy of CAR T cells targeting
Autor:
Lukas Braun, Erika L. Pearce, Bodo Grimbacher, Annette Schmitt-Graeff, Franziska M. Uhl, Dietmar Pfeifer, Barbara Sauer, Melanie Boerries, Joerg M. Buescher, Enrique de Vega Gomez, Justus Duyster, Geoffroy Andrieux, Stefan F. Martin, Robert Zeiser, Alla Bulashevska, Petya Apostolova, Michele Proietti, Philipp R. Esser, Eileen Haring, Marie Follo
Publikováno v:
Haematologica
Acute graft-versus-host disease causes significant mortality in patients undergoing allogeneic hematopoietic cell transplantation. Immunosuppressive treatment for graft-versus-host disease can impair the beneficial graft-versus-leukemia effect and fa
Autor:
Ralph Wäsch, Robert Zeiser, Hartmut Bertz, Reinhard Marks, Gabriele Ihorst, Jesus Duque-Afonso, Mehtap Yücel, Jürgen Finke, TC Köhler, Joachim Müller-Quernheim, Miguel Waterhouse
Publikováno v:
Bone Marrow Transplantation
The age of patients undergoing allogeneic hematopoietic cell transplantation (allo-HCT) has increased during the last decades, mainly due to improved reduced-intensity/toxicity conditioning protocols. A reduced-intensity conditioning based on fludara