Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Liana Adam"'
Autor:
Rachna T. Shroff, J. Morris, Kanwal Pratap Singh Raghav, Scott Kopetz, Liana Adam, Michael J. Overman, David R. Fogelman, J. Wang, Arvind Dasari, Cathy Eng, Eduardo Vilar, Enusha Karunasena, Nilofer S. Azad, R. Pisanic, Robert A. Wolff, Bryan K. Kee
Background Hypermethylation of promoter CpG islands [CpG island methylator phenotype (CIMP)] represents a unique pathway for the development of colorectal cancer (CRC), characterized by lack of chromosomal instability and a low rate of adenomatous po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d27d159bcf45db84d9859599c0cfe769
https://europepmc.org/articles/PMC5834085/
https://europepmc.org/articles/PMC5834085/
Autor:
T. R. Pisanic, Enusha Karunasena, David R. Fogelman, Robert A. Wolff, Scott Kopetz, Jing Wang, Liana Adam, J. Morris, Cathy Eng, Nilofer S. Azad, Eduardo Vilar, Michael J. Overman, Arvind Dasari, Kanwal Pratap Singh Raghav, Bryan K. Kee, Rachna T. Shroff
Publikováno v:
Annals of Oncology. 30:495
Autor:
Lixia Diao, Chang Gong Liu, David A. Jackson, Liana Adam, Alexander Zien, Colin P.N. Dinney, Wang Jing, Jitao D. Zhang, Matthew F. Wszolek
Publikováno v:
Urologic Oncology: Seminars and Original Investigations. 31:1701-1708
Bladder cancer (BC) is a burdensome disease with significant morbidity, mortality, and cost. The development of novel plasma-based biomarkers for BC diagnosis and surveillance could significantly improve clinical outcomes and decrease health expendit
Autor:
Wassim Kassouf, Teruo Inamoto, Peter C. Black, Mark B. Fisher, David Gallagher, David J. McConkey, Colin P.N. Dinney, Gordon A. Brown, Liana Adam, Tony Luongo, Menashe Bar-Eli
Publikováno v:
Journal of Urology. 180:1146-1153
The epidermal growth factor receptor inhibitor gefitinib (Iressa) is currently being studied in patients with bladder cancer and it has significant anti-angiogenic activity. We investigated the relationship between the modulation of vascular endothel
Autor:
Mark F. Munsell, Ameeta Arora, Marissa Shrader, David J. McConkey, Liana Adam, Teruo Inamoto, Colin P.N. Dinney, Xifeng Wu, Arlene O. Siefker-Radtke, Gordon A. Brown, Dan Theodorescu, Peter C. Black, Menashe Bar-Eli
Publikováno v:
Clinical Cancer Research. 14:1478-1486
Purpose: Epidermal growth factor receptor (EGFR) is an attractive target for the treatment of urothelial carcinoma, but a clinical response can be expected in only a small proportion of patients. The aim of this study was to define molecular markers
Autor:
Jolanta Bondaruk, Tomasz Tuziak, David J. McConkey, Menashe Bar-Eli, Bogdan Czerniak, Liana Adam, Colin P.N. Dinney, Wassim Kassouf, Sangkyou Lee, Keith A. Baggerly, Gordon A. Brown, Caimiao Wei, Peter C. Black
Publikováno v:
Journal of Urology. 179:353-358
Expression of various members of the ErbB family (epidermal growth factor receptor/ErbB-1, ErbB-2, ErbB-3 and ErbB-4) is associated with disease stage and survival in patients with urothelial carcinoma. We examined the correlation of ErbB family rece
Publikováno v:
Journal of Urology. 176:787-792
We determined the sequence specific efficacy of gefitinib and docetaxel treatment for bladder cancer. This combination was selected because it is currently under study in a phase II clinical trial.In vitro antiproliferative effects of gefitinib, doce
Autor:
Arlene O. Siefker-Radtke, David J. McConkey, Colin P.N. Dinney, Tomasz Tuziak, Bogdan Czerniak, Randall E. Millikan, Anita L. Sabichi, Xifeng Wu, Menashe Bar-Eli, Ashish M. Kamat, William F. Benedict, Liana Adam, H. Barton Grossman
Publikováno v:
Cancer Cell. 6:111-116
Supported by NIH Specialized Programs of Research Excellence Grant in Genitourinary Cancer CA91846, and National Cancer Institute Grants CA16672, CA066723, and CA85078.
Autor:
Yao Yu, Jerry Fowler, Scott Kopetz, Wenhui Wu, Francis A. San Lucas, Paul Scheet, Michael J. Overman, Huamin Wang, Liana Adam, Chad D. Huff
Publikováno v:
Journal of Clinical Oncology. 35:e15800-e15800
e15800 Background: Small bowel adenocarcinoma (SBA) is a rare malignancy of the digestive tract with limited knowledge about its genetic alterations. Methods: Eighteen tumor and normal matched samples were sequenced using the whole-exome-Illumina pla
Autor:
David G. Menter, Scott Kopetz, Zhi-Qin Jiang, Funda Meric-Bernstam, Michael J. Overman, Arvind Dasari, Ji Wu, Mary Brimer, Jisu Oh, Bryan K. Kee, Jeffrey S. Morris, Van K. Morris, Kanwal Pratap Singh Raghav, Liana Adam, David R. Fogelman, Feng Tian
Publikováno v:
Journal of Clinical Oncology. 34:3563-3563
3563Background: The PI3K / AKT pathway has several roles in CRC growth and progression through downstream targets including the MAPK pathway. Based on strong preclinical mCRC and non-mCRC clinical ...