Zobrazeno 1 - 10
of 144
pro vyhledávání: '"James N. Atkins"'
BRCA1 Protein Expression Predicts Survival in Glioblastoma Patients from an NRG Oncology RTOG Cohort
Autor:
Aidnag Z. Diaz, James N Atkins, Lydia Komarnicky, Jonathan P.S. Knisely, Steven P. Howard, David L. Rimm, Maria Vassilakopoulou, Jason A. Hanna, Veronique Neumeister, Edward Melian, Christopher J. Schultz, Corey J. Langer, Peixin Zhang, Michael D. Prados, Minhee Won, Adam P. Dicker, Luis Souhami, Walter J. Curran
Publikováno v:
Oncology
Purpose: Glioblastoma, the most common malignant brain tumor, was associated with a median survival of Methods and Materials: A TMA composed of archived glioblastoma tumors from patients treated with surgery, radiation, and non-TMZ chemotherapy, wa
Autor:
Kimmie Ng, Charles D. Blanke, Robert J. Mayer, Eileen M. O'Reilly, Brendan J. Guercio, Kaori Sato, Jeffrey A. Meyerhardt, Bert H. O'Neil, Alan P. Venook, Fang-Shu Ou, Howard S. Hochster, Sui Zhang, James N. Atkins, Blase N. Polite, Richard M. Goldberg, Erin L. Van Blarigan, Charles S. Fuchs, Donna Niedzwiecki, James Edward Shaw, Federico Innocenti, Heinz-Josef Lenz
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, vol 37, iss 29
PURPOSE Regular physical activity is associated with reduced risk of recurrence and mortality in patients with nonmetastatic colorectal cancer. Its influence on patients with advanced/metastatic colorectal cancer (mCRC) has been largely unexplored. P
Autor:
Anthony J. Olszanski, Patrick M. Forde, Olivier Rixe, Yanyan Lou, Asha Nayak-Kapoor, David S. Hong, Vi K. Chiu, Floyd Fox, Margaret A. Marshall, Agron Collaku, Tomislav Dragovich, Rom Leidner, James N. Atkins
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 28(3)
Purpose: The aim of the study was to determine safety, antitumor activity, and pharmacodynamic profile of mogamulizumab, an anti-CCR4 monoclonal antibody targeting effector regulatory T cells (Treg) in combination with the checkpoint inhibitor nivolu
Autor:
Alan P. Venook, Sui Zhang, Erin L. Van Blarigan, Edward Giovannucci, Donna Niedzwiecki, Mingyang Song, Alexander Hantel, Fang-Shu Ou, Shuji Ogino, James N. Atkins, Leonard B. Saltz, Al B. Benson, Charles S. Fuchs, Robert J. Mayer, Jeffrey A. Meyerhardt
Publikováno v:
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, vol 27, iss 10
Background: Higher intake of long-chain ω-3 polyunsaturated fatty acids and nuts, rich plant sources of unsaturated fats, after colon cancer diagnosis are associated with improved survival. It is not known whether the amount or the distribution of o
Autor:
Kouros Owzar, Bryan P. Schneider, Donna Niedzwiecki, Yukihide Momozawa, Megan Li, Heinz-Josef Lenz, Chen Jiang, Michiaki Kubo, Flora Mulkey, Deanna L. Kroetz, Paula N. Friedman, Howard L. McLeod, Fei Shen, Alan P. Venook, William Kevin Kelly, Susan Halabi, Bert H. O'Neil, Howard S. Hochster, Federico Innocenti, Mark J. Ratain, Hope S. Rugo, James N. Atkins
Publikováno v:
Clinical Cancer Research. 24:4734-4744
Purpose: Bevacizumab is a VEGF-specific angiogenesis inhibitor indicated as an adjunct to chemotherapy for the treatment of multiple cancers. Hypertension is commonly observed during bevacizumab treatment, and high-grade toxicity can limit therapy or
Autor:
Edward Giovannucci, Eric G. Wolfe, Federico Innocenti, Fang-Shu Ou, Chloe E. Atreya, Charles D. Blanke, James E. Shaw, Kimmie Ng, Charles S. Fuchs, Sui Zhang, Richard M. Goldberg, Alan Venlo, Jeffrey A. Meyerhardt, Robert J. Mayer, Blase N. Polite, Erin L. Van Blarigan, James N. Atkins, Bert H. O'Neil, Eileen M. O'Reilly, Howard S. Hochster, Donna Niedzwiecki, Heinz-Josef Lenz, Katherine Van Loon
Publikováno v:
JAMA Network Open
Key Points Question Is diet quality at initiation of first-line treatment for metastatic colorectal cancer associated with overall survival? Findings In this cohort study including 1284 people with metastatic colorectal cancer enrolled between 2005 a
Autor:
Benson Al Bowen, Bert H. O'Neil, Alan P. Venook, Blase N. Polite, Robert J. Mayer, Sui Zhang, Michael Pollak, Eileen M. O'Reilly, James Edward Shaw, Charles D. Blanke, Donna Niedzwiecki, Brian C. Mullen, Fang-Shu Ou, James N. Atkins, Jeffrey A. Meyerhardt, Charles S. Fuchs, Heinz-Josef Lenz, Justin C. Brown, Andrew B. Nixon, Richard M. Goldberg, Federico Innocenti, Brendan J. Guercio
Publikováno v:
JNCI Cancer Spectrum
Background Energy balance-related biomarkers are associated with risk and prognosis of various malignancies. Their relationship to survival in metastatic colorectal cancer (mCRC) requires further study. Methods Baseline plasma insulin-like growth fac
Autor:
Sui Zhang, Charles D. Blanke, Justin C. Brown, Robert J. Mayer, James N. Atkins, Donna Niedzwiecki, James Edward Shaw, Federico Innocenti, Brian C. Mullen, Heinz-Josef Lenz, Jeffrey A. Meyerhardt, Fang-Shu Ou, Charles S. Fuchs, Blase N. Polite, Bert H. O'Neil, Alan P. Venook, Howard S. Hochster, Richard M. Goldberg, Eileen M. O'Reilly, Brendan J. Guercio
Publikováno v:
JNCI Cancer Spectrum
BackgroundIn nonmetastatic colorectal cancer, overweight and mild-to-moderately obese patients experience improved outcomes compared with other patients. Obesity’s influence on advanced or metastatic colorectal cancer (mCRC) is relatively unexplore
Autor:
Jean Francois Boileau, Virginia F. Borges, Kathy S. Albain, Timothy David Moore, Norman Wolmark, André Robidoux, James N. Atkins, Eleftherios P. Mamounas, Reena S. Cecchini, Sandra M. Swain, Patrick J. Flynn, Joseph P. Costantino, Louise Provencher, Charles E. Geyer, Christopher Stokoe, Louis Fehrenbacher, Priya Rastogi, Soonmyung Paik, John Crown, Jonathan Polikoff
Publikováno v:
J Clin Oncol
PURPOSE Adjuvant trastuzumab reduces invasive breast cancer (IBC) recurrence and risk for death in patients with HER2-amplified or overexpressing IBC. A subset of patients in the landmark trastuzumab adjuvant trials who originally tested HER2-positiv
Autor:
Heinz-Josef Lenz, Blase N. Polite, Donna Niedzwiecki, Crystal S. Denlinger, Justin C. Brown, Robert J. Mayer, Sui Zhang, Jeffrey A. Meyerhardt, Fang-Shu Ou, Bert H. O'Neil, Alan P. Venook, Kimmie Ng, Federico Innocenti, Eileen M. O'Reilly, Richard M. Goldberg, Charles D. Blanke, James N. Atkins, James E. Shaw, Charles S. Fuchs
Publikováno v:
JNCI Cancer Spectrum
Background Diabetes is a prognostic factor for some malignancies, but its association with outcome in patients with advanced or metastatic colorectal cancer (CRC) is less clear. Methods This cohort study was nested within a randomized trial of first-