Zobrazeno 81 - 90
of 411
pro vyhledávání: '"Irene M. Ghobrial"'
Autor:
Omar Nadeem, Robert Redd, Laura V. Stampleman, Jeffrey V. Matous, Andrew J. Yee, Jeffrey A. Zonder, Andrew Kin, Jacalyn Rosenblatt, Mark Bustoros, MD, Julia Prescott, Alexandra Savell, Kathleen Guimond, Erin Frey, Rachel Styles, Adrienne Bielawski, Cody J Boehner, Nang Kham Su, Multiple Myeloma Research Foundation Multiple Myeloma Research Foundation, The Leukemia & Lymphoma Society The Leukemia & Lymphoma Society, BCRP Blood Cancer Research Partnership, Adam S Sperling, Giada Bianchi, Jacob P. Laubach, Jorge J. Castillo, Nikhil C. Munshi, Kenneth C. Anderson, Paul G. Richardson, Lorenzo Trippa, Irene M. Ghobrial
Publikováno v:
Blood. 134:1898-1898
Introduction: Daratumumab (DARA) is an anti-CD38 monoclonal antibody that is approved for use in patients with newly diagnosed and relapsed multiple myeloma (MM). We hypothesized that early therapeutic intervention with DARA in patients with high-ris
Autor:
Stefano Malvestiti, Sonia Vallet, Hartmut Goldschmidt, Yuji Mishima, Eugenio Morelli, Irene M. Ghobrial, Latifa Bakiri, Anja Seckinger, Erwin F. Wagner, Martin Percherstorfer, Dirk Jaeger, Martin Sattler, Chunyan Sun, Yu Hu, Yujia Shen, Aldo M. Roccaro, Piefrancesco Tassone, Klaus Podar, Fengjuan Fan, Dirk Hose
Publikováno v:
Blood. 134:4341-4341
A significant increase in bone marrow (BM) angiogenesis represents a key event in early, microenvironment-dependent, multiple myeloma (MM). Angiogenic growth factor- and cytokine- production and secretion is a complex process regulated by a plethora
Autor:
Hannah Lyons, Robert A. Redd, Robert L. Schlossman, Nikhil C. Munshi, Kenneth C. Anderson, Irene M. Ghobrial, Philip M. Wade, Kathleen J. Lively, Jacob P. Laubach, Frank G. Basile, Elizabeth O'Donnell, Paul G. Richardson, Cynthia C. Harrington, Carol Ann Huff, Andrew Yee, Claudia E. Paba-Prada, Jill N. Burke, Noopur Raje
Publikováno v:
Blood. 134:3178-3178
PURPOSE: This updated analysis examined survival outcomes after 60 months of follow-up in patients with transplant-ineligible newly diagnosed multiple myeloma (NDMM) treated with the 3-drug regimen of modified lenalidomide-bortezomib-dexamethasone (R
Autor:
Irene M. Ghobrial, Gabriela S. Hobbs, Valentina Nardi, David J. Kuter, Annemarie E. Fogerty, Nicholas A. Jessop, Donna Neuberg, Nathan T. Connell, Chi-Joan How, Jennifer Lombardi Story, Nancy Higgins, Jean M. Connors, Orly Leiva, Geoffrey Fell, Jeffrey I. Zwicker, Thomas Bogue, Ann Mullally, Rachel Styles, Mark Bustoros
Publikováno v:
Blood. 134:4172-4172
BACKGROUND: Myeloproliferative neoplasms (MPNs) including essential thrombocythemia (ET) and polycythemia vera (PV) are commonly diagnosed in the sixth decade, but as many as 20% of patients are younger than 40. This introduces the possibility of pre
Autor:
Jonathan J Keats, Henry Dumke, Brendan Reardon, Daniel Auclair, Donna Neuberg, Kalvis Hornburg, Romanos Sklavenitis-Pistofidis, Nikhil C. Munshi, Christopher J. Gibson, Marzia Capelletti, Jacob P. Laubach, Paul G. Richardson, Robert L. Schlossman, Amin Nassar, David P. Steensma, Matthew Leventhal, Robert A. Redd, Chip Stewart, Irene M. Ghobrial, Jerome Ritz, Cody J. Boehner, Muhieddine M. Itani, Salomon Manier, Daisy Huynh, Jihye Park, Eliezer M. Van Allen, Saud H. AlDubayan, Benjamin L. Ebert, Kenneth C. Anderson, Sabrin Tahri, Mark Bustoros, Tarek H. Mouhieddine, Robert J. Soiffer, Shaadi Mehr, Adam S. Sperling, Gad Getz, Chia Jen Liu
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 19:e15
Autor:
Romanos Sklavenitis-Pistofidis, Adriana Peilla Glen, Irene M. Ghobrial, Daisy Huynh, Luca Pinello, Mark Bustoros, Kendell Clement, Jihye Park, Mahshid Rahmat, Brianna Berrios, David M. Dorfman, Tarek H. Mouhieddine
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 19:e74
Autor:
Irene M. Ghobrial, Salomon Manier, Romanos Sklavenitis-Pistofidis, Brianna Berrios, Yujia Shen, Sabrin Tahri
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 19:e110
Autor:
Gad Getz, Rafael Fonseca, Patrice Soule, Brianna Berrios, Mark Bustoros, Ivan Borrello, Irene M. Ghobrial, Timothy R. Rebbeck, Courtney Hamilton, Allison Higgins, Kathleen Guimond, David Oluwadara, Annie Cowan, David L. Murray, Chip Stewart, Catherine R. Marinac, Nang Su, Viktor A. Adalsteinsson, Nader Shayegh, Jeremiah A. Johnson, Oksana Zavidij
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 19:e310
Autor:
Mahshid Rahmat, Yuji Mishima, Yu J. Shen, Katsutoshi Kokubun, Marta Chesi, Naoka Murakami, Esilida Sula Karreci, Jiantao Shi, Yu-Tzu Tai, Daisy Huynh, Irene M. Ghobrial, Romanos Sklavenitis Pistofidis, Michele Moschetta, Mairead Reidy, P. Leif Bergsagel, Pavlo Lukyanchykov, Antonio Sacco, Mark Bustoros, Satoshi Takagi, Jihye Park, Shokichi Tsukamoto, Oksana Zavidij, Aldo M. Roccaro, Salomon Manier, Yawara Kawano, Jamil Azzi, Tarek H. Mouhieddine
Despite significant advances in the treatment of multiple myeloma (MM), most patients succumb to disease progression. One of the major immunosuppressive mechanisms that is believed to play a role in myeloma progression is the expansion of regulatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccd4d932e74e4f895db966f83ede35e7
https://europepmc.org/articles/PMC5983341/
https://europepmc.org/articles/PMC5983341/
Publikováno v:
British journal of haematology. 181(4)
Multiple myeloma (MM) is the second most common haematological malignancy after non-Hodgkin lymphoma. Despite the improvement in outcomes over the last decade with the introduction of novel therapies, such as immunomodulatory agents (IMiDs) and prote