Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Guillaume Cognet"'
Autor:
Jean-Emmanuel Sarry, Thomas Farge, Eléonore Kaphan, Emeline Boet, Francois Vergez, Marie Sabatier, Jérôme Kluza, Nathalie Nicot, Yujue Wang, Andrew H. Wei, Aurélie Bousard, Noémie Gadaud, Pierre-Luc Mouchel, Ambrine Sahal, Nesrine Aroua, Ing Soo Tiong, Nathaniel Polley, Lucille Stuani, Mathilde Gotanègre, Quentin Fovez, Tony Kaoma, Laura Poillet-Perez, Claudie Bosc, Estelle Saland, Marie Tosolini, Guillaume Cognet, Rafael J. Argüello, Florian Rambow, Jean-Jacques Fournié, Christian Recher, Carine Joffre, Clément Larrue, Xiaoyang Su, Jean-Christophe Marine, Jerome Tamburini, Céline Mazzotti, Muriel Picard, Hervé Avet-Loiseau, Florence Cabon, Latifa Jarrou
Publikováno v:
Nature Cancer
Nature Cancer, 2021, 2 (11), pp.1204-1223. ⟨10.1038/s43018-021-00264-y⟩
Nature Cancer, 2021, 2 (11), pp.1204-1223. ⟨10.1038/s43018-021-00264-y⟩
Therapy resistance represents a major clinical challenge in acute myeloid leukemia (AML). Here we define a ‘MitoScore’ signature, which identifies high mitochondrial oxidative phosphorylation in vivo and in patients with AML. Primary AML cells wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82b53df2ce4295c18f2bfd97c1ac0618
https://amu.hal.science/hal-03565962
https://amu.hal.science/hal-03565962
Autor:
Pierre Bories, Sonia Zaghdoudi, Jean-Emmanuel Sarry, Florence Castelli, Héléna Boutzen, Alexis Hucteau, Sarah Bertoli, Marie Sabatier, Ambrine Sahal, Laura Lauture, Thomas Farge, Vera Pancaldi, Emeline Chu-Van, Lucille Stuani, Emeline Boet, Nathaniel Polley, Christian Récher, Nathan Guiraud, Guillaume Cognet, Estelle Saland, Véronique Mansat-De Mas
Publikováno v:
Cancers
Volume 13
Issue 20
Cancers, Vol 13, Iss 5243, p 5243 (2021)
Volume 13
Issue 20
Cancers, Vol 13, Iss 5243, p 5243 (2021)
Simple Summary Around 15% of acute myeloid leukemia (AML) patients harbor mutations in isocitrate dehydrogenases (IDH), which lead to the production of the oncometabolite 2-hydroxyglutarate (2-HG). Inhibitors of mutant IDH enzymes and their 2-HG prod