Zobrazeno 1 - 10
of 135
pro vyhledávání: '"David S. Ziegler"'
Autor:
Johannes H. Schulte, C. Michel Zwaan, David S. Ziegler, Michela Casanova, Matthias Fischer, Mario Stegert, Beate Wulff, Constantino Sábado, Meredith S. Irwin, Luojun Wang, Birgit Geoerger, Fabrice Branle, Felipe K. Hurtado, Lynley V. Marshall, Lucas Moreno
Publikováno v:
The Lancet Oncology, 22(12), 1764-1776. Lancet Publishing Group
Background: Several paediatric malignancies, including anaplastic large cell lymphoma (ALCL), inflammatory myofibroblastic tumour (IMT), neuroblastoma, and rhabdomyosarcoma, harbour activation of anaplastic lymphoma kinase (ALK) through different mec
Autor:
Hiroaki Goto, Laura Dima, Steven G. DuBois, Ricarda Norenberg, Jordan R. Hansford, Esther De La Cuesta, Juneko E. Grilley-Olson, Ingrid Øra, David S. Hong, Theodore W. Laetsch, Karsten Nysom, Joanna Stefanowicz, Martin Højgaard, Valentina Boni, Hyoung Jin Kang, Julia C. Chisholm, Makoto Tahara, Birgit Geoerger, François Doz, Soledad Gallego-Melcon, David S. Ziegler, Alexander Drilon, Cornelis M. van Tilburg, Hyun Cheol Chung, Anne Thorwarth, Igor T. Gavrilovic, Antoine Italiano, Michael Capra, Sébastien Perreault, Nicolas U. Gerber
Publikováno v:
Neuro-Oncology. 24:997-1007
Background Larotrectinib is a first-in-class, highly selective tropomyosin receptor kinase (TRK) inhibitor approved to treat adult and pediatric patients with TRK fusion-positive cancer. The aim of this study was to evaluate the efficacy and safety o
Autor:
Michelle Haber, Rachael L. Terry, Joe Zhu, Paul J Neeson, Phillip K. Darcy, Deborah Meyran, David S. Ziegler, Paul G Ekert, Joseph A. Trapani
Publikováno v:
Annals of Oncology. 32:1366-1380
Chimeric antigen receptor (CAR)-T-cell therapy is a promising approach for the treatment of childhood cancers, particularly high-risk tumors that fail to respond to standard therapies. CAR-T cells have been highly successful in treating some types of
Autor:
Jane E. Minturn, Ayman El-Sheikh, Gustavo Sevlever, Michelle Monje-Deisseroth, Hetal Dholaria, Karen Tsui, Maryam Fouladi, Pratiti Bandopadhayay, Cynthia Hawkins, Scott L Coven, Lindsay Kilburn, Christopher L. Tinkle, David S. Ziegler, Eric Sandler, Yvan Samson, Jordan R. Hansford, Eric Bouffet, Sylvia Cheng, Sridharan Gururangan, Kathleen Dorris, Tim Hassall, Mohamed S. Zaghloul, Carl Koschmann, Sarah Leary, Mercedes Garcia Lombardi, Blaise V. Jones, Paul G. Fisher, Anthony Asher, Rachid Drissi, Blanca Diez, Kenneth J. Cohen, Jie Ma, Adriana Fonseca, Katie Black, Nicholas G. Gottardo, Stewart Goldman, Christine E. Fuller, Tabitha Cooney, Moatasem El-Ayadi, Adam Lane, Brooklyn Chaney, Mariko DeWire, Robert J. Greiner, Ute Bartels, Margot A Lazow, James L. Leach, Lars M. Wagner, Roger J. Packer
Publikováno v:
Neuro Oncol
Background Diffuse intrinsic pontine glioma (DIPG) remains a clinico-radiologic diagnosis without routine tissue acquisition. Reliable imaging distinction between DIPG and other pontine tumors with potentially more favorable prognoses and treatment c
Autor:
Lee Yi Yen, Melyssa Aronson, Carol J. Swallow, Cynthia Hawkins, Lara Reichman, Rebecca C. Luiten, Sumita Roy, Michal Zapotocky, Patrick Tomboc, Christian Kratz, Michael Osborn, Junne Kamihara, Ayse Bahar Ercan, Jamie L. Maciaszek, Vanessa Bianchi, Benjamin Oshrine, Hagit N. Baris, Ossama M. Maher, Mohsin Rashid, Sara Rhode, Sharon Gardner, Annika Bronsema, David S. Ziegler, An Van Damme, Monica Newmark, Mithra Ghalibafian, Heather Hampel, Jordan R. Hansford, Vahid Fallah Azad, Michael P. Link, Simon C. Ling, Marc Remke, Shayna Zelcer, Deborah T. Blumenthal, Isabelle Scheers, Rebecca Loret De Mola, Syed Ahmer Hamid, Vanan MagimairajanIssai, Kim E. Nichols, Saunders Hsu, Catherine Goudie, Naureen Mushtaq, Ira Winer, Abeer Al-Battashi, Garth Nicholas, Roula Farah, Kami Wolfe Schneider, Rejin Kebudi, Jan Rapp, Gregory Thomas, Helen Toledano, Alvaro Lassaletta, Anne Bendel, Jeffrey Knipstein, Musa Alharbi, Gadi Abebe-Campino, Rose B. McGee, Anirban Das, Uri Tabori, Donald Basel, Alyssa Reddy, Melissa Edwards, Scott Lindhorst, Craig Harlos, Bailey Gallinger, Elizabeth Cairney, Anita Villani, Valerie Larouche, Rachel Pearlman, Maude Blundell, Gary Mason, David Sumerauer, Magnus Sabel, Aghiad Chamdin, Leslie Taylor, David Malkin, William D. Foulkes, Maura Massimino, Catherine Gilpin, Eric Bouffet, Miriam Bornhorst, Carol Durno, Enrico Opocher, Nobuko Hijiya, Zehavit Frenkel, David Samuel, Michal Lurye, Stefanie Zimmermann, Shani Caspi, Stefano Chiaravalli, David Gass, Eshetu G. Atenafu, Shlomi Constantini, Shay Ben-Shachar, Michal Yalon, Rina Dvir, Daniel Pettee, Bruce Crooks, Santanu Sen, Carl Koschmann, Raymond Bedgood, Theodore Nicolaides, Duncan Stearns, Yael Goldberg, Melissa Galati, Gabriel Robbins
Publikováno v:
Paediatrics Publications
Journal of Clinical Oncology, Vol. 39, no.25, p. 2779-2790 (2021)
Journal of Clinical Oncology, Vol. 39, no.25, p. 2779-2790 (2021)
PURPOSE Constitutional mismatch repair deficiency syndrome (CMMRD) is a lethal cancer predisposition syndrome characterized by early-onset synchronous and metachronous multiorgan tumors. We designed a surveillance protocol for early tumor detection i
Autor:
Hao-Wen Sim, Kirston Barton, Zarnie Lwin, Jonathon Parkinson, Neda Haghighi, Elizabeth Hovey, Robyn Leonard, Hui K Gan, Benjamin Y. Kong, Mustafa Khasraw, Matthew Foote, David S. Ziegler, Anna K. Nowak, Candace Carter
Publikováno v:
Asia-Pacific Journal of Clinical Oncology. 18:259-266
Aim The neuro-oncology community in Australia is well positioned to collaborate internationally, with a motivated trials group, strong regulatory bodies and an attractive fiscal environment. We sought to identify gaps in the Australian neuro-oncology
Autor:
Craig Erker, Adam Lane, Brooklyn Chaney, Sarah Leary, Jane E Minturn, Ute Bartels, Roger J Packer, Kathleen Dorris, Nicholas G Gottardo, Katherine E Warren, Alberto Broniscer, Mark W Kieran, Xiaoting Zhu, Peter White, Phillip J Dexheimer, Katie Black, Anthony Asher, Mariko DeWire, Jordan R Hansford, Sridharan Gururangan, Javad Nazarian, David S Ziegler, Eric Sandler, Allison Bartlett, Stewart Goldman, Chie-Schin Shih, Tim Hassall, Hetal Dholaria, Pratiti Bandopadhayay, Yvan Samson, Michelle Monje, Paul G Fisher, Andrew Dodgshun, Sarah Parkin, Murali Chintagumpala, Karen Tsui, David Gass, Valerie Larouche, Emmett Broxson, Mercedes Garcia Lombardi, Stacie Shiqi Wang, Jie Ma, Cynthia Hawkins, Dima Hamideh, Lars Wagner, Carl Koschmann, Christine Fuller, Rachid Drissi, Blaise V Jones, James Leach, Maryam Fouladi
Publikováno v:
Neuro Oncol
BackgroundDiffuse intrinsic pontine gliomas (DIPG) generally occur in young school-age children, although can occur in adolescents and young adults. The purpose of this study was to describe clinical, radiological, pathologic, and molecular character
Autor:
Jinhan Xie, Paulette Barahona, Michelle Haber, Emily Mould, Andrew J. Gifford, Loretta Lau, Amit Kumar, Timothy W. Failes, Marie Wong-Erasmus, Dylan Grebert-Wade, Greg M. Arndt, M. Emmy M. Dolman, Dong-Anh Khuong-Quang, Chelsea Mayoh, Kanika Bhatia, Shu-Oi Chow, Alvin Kamili, Roxanne Cadiz, Richard B. Lock, Maria Tsoli, Vanessa Tyrrell, David S. Ziegler, Glenn M. Marshall, Penny Athanasatos
Publikováno v:
Cancer Cytopathology. 129:805-818
Background The development of high-throughput drug screening (HTS) using primary cultures provides a promising, clinically translatable approach to tailoring treatment strategies for patients with cancer. However, this has been challenging for solid
Autor:
Loretta Lau, Janine Vetsch, David S. Ziegler, Brittany C. McGill, David Malkin, Meera Warby, Katherine M. Tucker, Emily Duve, Claire E. Wakefield
Publikováno v:
JCO precision oncology. 3
PURPOSE Children with high-risk cancers have low survival rates because current treatment options are limited. Precision medicine trials are designed to offer patients individualized treatment recommendations, potentially improving their clinical out
Autor:
Jane E. Minturn, Ute Bartels, Nicholas G. Gottardo, Jordan R. Hansford, Christine Fuller, Cynthia Hawkins, Renee Doughman, Mariko DeWire-Schottmiller, Sarah Leary, Brooklyn Chaney, Blaise V. Jones, Michelle Monje-Deisseroth, James Roebker, Katherine E. Warren, Hetal Dholaria, Austin Schafer, Rachid Drissi, Adam Lane, Joshua J Baugh, Roger J. Packer, James L. Leach, Paul G. Fisher, Stewart Goldman, Stacie S. Wang, Maryam Fouladi, David S. Ziegler
Publikováno v:
Neuro Oncol
Abtract Background This study describes imaging features of diffuse intrinsic pontine glioma (DIPG) and correlates with overall survival (OS) and histone mutation status in the International DIPG Registry (IDIPGR). Methods Four hundred cases submitte