Zobrazeno 1 - 10
of 229
pro vyhledávání: '"Anna Mae Diehl"'
Autor:
Manal F. Abdelmalek, Jeongeun Hyun, Steven R. Patierno, Rebecca Caffrey, Cynthia A. Moylan, Muthana Al Abo, Anna Mae Diehl, Xiyou Zhou, Seh-Hoon Oh, Arun J. Sanyal, Kun Xiang, Rajesh Kumar Dutta, Raquel Maeso-Díaz, Jennifer A. Freedman
Publikováno v:
J Hepatol
Background & Aims Non-alcoholic fatty liver disease (NAFLD), the hepatic correlate of the metabolic syndrome, is a major risk factor for hepatobiliary cancer (HBC). Although chronic inflammation is thought to be the root cause of all these diseases,
Autor:
Colby Ayers, Kara Wegermann, Vanessa Blumer, Robert W. McGarrah, Ambarish Pandey, Cynthia A. Moylan, Anna Mae Diehl, Tarek Bekfani, Anthony E. Peters, Manal F. Abdelmalek, Marat Fudim, Justin L. Grodin
Publikováno v:
ESC Heart Failure, Vol 8, Iss 2, Pp 842-848 (2021)
ESC Heart Failure
ESC Heart Failure
Aims Non‐alcoholic fatty liver disease leads to progressive liver fibrosis and appears to be a frequent co‐morbid disease in heart failure with preserved ejection fraction (HFpEF). It is well known that liver fibrosis severity predicts future liv
Autor:
Alisha Mavis, Kara Wegermann, Ayako Suzuki, Cynthia A. Moylan, Anna Mae Diehl, Manal F. Abdelmalek
Publikováno v:
Hepatology. 73:1199-1206
Sex and Menopause Modify the Effect of Single Nucleotide Polymorphism Genotypes on Fibrosis in NAFLD
Autor:
Jiayin Zheng, Anna Mae Diehl, Cynthia D. Guy, Ayako Suzuki, Kara Wegermann, Allison E. Ashley-Koch, Shein-Chung Chow, Andrea D. Coviello, Melanie E. Garrett, Cynthia A. Moylan, Manal F. Abdelmalek
Publikováno v:
Hepatology Communications, Vol 5, Iss 4, Pp 598-607 (2021)
Hepatology Communications
Hepatology Communications
The development of fibrosis in nonalcoholic fatty liver disease (NAFLD) is influenced by genetics, sex, and menopausal status, but whether genetic susceptibility to fibrosis is influenced by sex and reproductive status is unclear. Our aim was to iden
Publikováno v:
Clin Liver Dis (Hoboken)
Watch a video presentation of this article Watch an interview with the author Answer questions and earn CME.
Gut-microbiome-inflammation interactions have been linked to neurodegeneration in Alzheimer’s disease (AD) and other disorders. We hypothesized that treatment with rifaximin, a minimally absorbed gut-specific antibiotic, may modify the neurodegener
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d58ad9f91d26fec40bbc761a4d35564a
https://doi.org/10.1101/2021.11.22.21266123
https://doi.org/10.1101/2021.11.22.21266123
Autor:
Rohan Khera, Kara Wegermann, Manal F. Abdelmalek, Kershaw V. Patel, Lin Zhong, Cynthia A. Moylan, Anna Mae Diehl, Robert W. McGarrah, Vishal N. Rao, Ethan A. Halm, Ian J. Neeland, Marat Fudim, Ambarish Pandey, Sandeep R Das, Jeroen Molinger
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 22 (2021)
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Nonalcoholic fatty liver disease (NAFLD) and heart failure (HF) are increasing in prevalence. The independent association between NAFLD and downstream risk of HF and HF subtypes (HF with preserved ejection fraction and HF with reduced ejec
Autor:
Tianyi Chen, Jeongeun Hyun, Ali Ahmadi, Hidekazu Tsukamoto, Zhaoli Sun, Kuo Du, Ullas V. Chembazhi, Anna Mae Diehl, Ivan Rusyn, Sushant Bangru, Auinash Kalsotra
Publikováno v:
J Clin Invest
Severe alcoholic hepatitis (SAH) is a deadly liver disease without an effective medical therapy. Although SAH mortality is known to correlate with hepatic accumulation of immature liver cells, why this occurs and how it causes death are unclear. Here
Autor:
Jun Zhang, Roger J. Davis, Meng Li, Christopher Q. Chen, Anna Mae Diehl, Mariam Aghajan, Ying Wang, Robert Win Maw Min, Tin Aung Than, Sanda Win, Neil Kaplowitz, Yibu Chen, Manal F. Abdelmalek, Filbert W.M. Aung, Ayako Suzuki
Publikováno v:
Journal of Clinical Investigation. 129:5278-5293
SH3 domain–binding protein that preferentially associates with Btk (SAB) is an outer-membrane docking protein for JNK-mediated impairment of mitochondrial function. Deletion of Sab in hepatocytes inhibits sustained JNK activation and cell death. Th
Autor:
Anna Mae Diehl, Oliver Glass, Elizabeth Bechard, Jane F. Pendergast, Cynthia D. Guy, Daniel Liu, Manal F. Abdelmalek
Publikováno v:
Hepatology Communications
Hepatology Communications, Vol 6, Iss 2, Pp 334-344 (2022)
Hepatology Communications, Vol 6, Iss 2, Pp 334-344 (2022)
Exercise is a foundational treatment for nonalcoholic fatty liver disease (NAFLD); however, the majority of patients are unable to initiate and maintain effective exercise habits and remain at increased risk for progressive liver disease. Barriers an