Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Andres J. Klein-Szanto"'
Autor:
John W. Tobias, Mario Andres Blanco, Snahlata Singh, Sushil Kumar, Alana L. Welm, Christopher J. Lengner, Rumela Chakrabarti, Yibin Kang, Christian W. Siebel, Andres J. Klein-Szanto, Ajeya Nandi, Rohan Regulapati, Ning Li
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Nature Communications
Development of chemoresistance in breast cancer patients greatly increases mortality. Thus, understanding mechanisms underlying breast cancer resistance to chemotherapy is of paramount importance to overcome this clinical challenge. Although activate
Publikováno v:
Biochemical Pharmacology. 164:336-341
Hypercholesterolemia represents a leading cause in the development of atherosclerotic plaques, increasing the risk for ACVS. It actually counts as a major cause of cardiovascular disease etiopathogenesis. The causes of hypercholesterolemia are multif
Autor:
Manabu Muto, Masataka Shimonosono, Takaaki Arigami, Amanda B. Muir, Masaki Mori, Takashi Kijima, Yuta Kasagi, Shinya Ohashi, Andres J. Klein-Szanto, Prasanna M. Chandramouleeswaran, Narayan G. Avadhani, Itaru Omoto, Shoji Natsugoe, Gregory G. Ginsberg, Seiji Naganuma, Veronique Giroux, Varun Sahu, Yoshiaki Shinden, Osamu Kikuchi, Devraj Basu, J. Alan Diehl, Yasuto Uchikado, Koji Tanaka, Yoshiaki Kita, Yuichiro Doki, Adam J. Bass, Ken Sasaki, Hiroshi Nakagawa, Anil K. Rustgi, Kelly A. Whelan, Takeo Hara
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 1, Pp 73-91 (2019)
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 1, Pp 73-91 (2019)
Background & Aims Oropharyngeal and esophageal squamous cell carcinomas, especially the latter, are a lethal disease, featuring intratumoral cancer cell heterogeneity and therapy resistance. To facilitate cancer therapy in personalized medicine, thre
Autor:
Joel Gabre, Jianwen Que, Angela J. Yoon, Ricardo Cruz-Acuna, Gary W. Falk, Shoji Natsugoe, Adam J. Bass, Julian A. Abrams, Tatiana A. Karakasheva, Lorenzo Ferri, Veena Sangwan, Anil K. Rustgi, Timothy C. Wang, Hiroshi Nakagawa, Varun Sahu, Kelly A. Whelan, Gregory G. Ginsberg, Elizabeth Philipone, J. Alan Diehl, Veronique Giroux, Hisatsugu Maekawa, Andres J. Klein-Szanto, Devraj Basu, Masataka Shimonosono, Takashi Kijima
Publikováno v:
Curr Protoc Stem Cell Biol
Esophageal cancers comprise adenocarcinoma and squamous cell carcinoma, two distinct histologic subtypes. Both are difficult to treat and among the deadliest human malignancies. We describe protocols to initiate, grow, passage, and characterize patie
Autor:
Kelly A. Whelan, Benjamin J. Wilkins, Okan U. Elci, Evan S. Dellon, Gary W. Falk, Jonathan Gross, Bridget Godwin, Andres J. Klein-Szanto, Hiroshi Nakagawa, Jonathan M. Spergel, Maureen DeMarshall, Amanda B. Muir, Medha Sharma, Alain Benitez, Chris A. Liacouras
Publikováno v:
Clin Gastroenterol Hepatol
Background & Aims Although eosinophil count is the standard used to monitor disease activity in patients with eosinophilic esophagitis (EoE), there are often disparities between patient-reported symptoms and eosinophil counts. We examined the prevale
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9caf01105763de1fa0d9d57e16578429
https://europepmc.org/articles/PMC7058491/
https://europepmc.org/articles/PMC7058491/
Autor:
Anbin Mu, Dorian Frazier, Alena Klochkova, Mohammad Faujul Kabir, Adam Karami, Kelly A. Whelan, Andres J. Klein-Szanto
Publikováno v:
Gastroenterology. 160:S-264
Autor:
Jennifer R. Pyle, V. Craig Jordan, Andres J. Klein-Szanto, Helen Kim, Joan S. Lewis-Wambi, Chris Wambi, Roshani R. Patel
Publikováno v:
Breast Cancer Research, Vol 20, Iss 1, Pp 1-3 (2018)
Breast Cancer Research : BCR
Breast Cancer Research : BCR
Introduction Estrogen deprivation using aromatase inhibitors is one of the standard treatments for postmenopausal women with estrogen receptor (ER)-positive breast cancer. However, one of the consequences of prolonged estrogen suppression is acquired
Autor:
Yuwaraj Kadariya, Andres J. Klein-Szanto, Arti Shukla, Jacqueline Talarchek, Mitchell Cheung, Kathy Q. Cai, Melpo Christofidou-Solomidou, Joseph R. Testa, Craig W. Menges, Ralph A. Pietrofesa, Brooke T. Mossman
Publikováno v:
Cancer Prevention Research. 9:406-414
Exposure to asbestos is causally associated with the development of malignant mesothelioma, a cancer of cells lining the internal body cavities. Malignant mesothelioma is an aggressive cancer resistant to all current therapies. Once inhaled or ingest
Autor:
Andrea Ventura, Riccardo Fodde, Antonio Percesepe, Alfonso Bellacosa, David P. Turner, Valentina Rovella, Maurizio Ponz de Leon, Karthik Devarajan, Juul T. Wijnen, Maurizio Genuardi, Pietro Mancuso, Salvatore Cortellino, Andres J. Klein-Szanto, Emanuela Lucci-Cordisco, Antonio Riccio, Rossella Tricarico, Heleen M. van der Klift, Pål Møller, Alessandra Viel, Kathy Q. Cai, Monica Pedroni, Paolo Radice, Lucio Bertario, Shantie Jagmohan-Changur, Giovanni Neri
Publikováno v:
Oncotarget
Oncotarget, 6(40), 42892-42904. Impact Journals LLC
Oncotarget, 6(40), 42892-42904. Impact Journals LLC
The DNA glycosylase gene MBD4 safeguards genomic stability at CpG sites and is frequently mutated at coding poly-A tracks in mismatch repair (MMR)-defective colorectal tumors (CRC). Mbd4 biallelic inactivation in mice provided conflicting results as
Autor:
Takeo Hara, Hiroshi Nakagawa, Masataka Shimonosono, Dominique Bailey, Julian A. Abrams, Rieko Shimonosono, Melanie A. Ruffner, Manti Guha, Andres J. Klein-Szanto, Jianwen Que, Gary W. Falk, Hisatsugu Maekawa, Amanda B. Muir, Jonathan M. Spergel
Publikováno v:
Gastroenterology. 158:S-178