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pro vyhledávání: '"Stanford J, Stewart"'
Autor:
Roger B. Cohen, Caio Rocha-Lima, Jan Baughman, Deryk Loo, Nancy L. Lewis, Lee S. Rosen, Suzanne F. Jones, Howard A. Burris, Lori Kunkel, Stanford J. Stewart, John L. Marshall
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 16(5)
Purpose: RAV12 is a high affinity, internalizing, chimeric IgG1 monoclonal antibody that binds RAAG12, a novel primate-restricted N-linked carbohydrate epitope present on multiple cell surface proteins. RAAG12 is highly expressed on many adenocarcino
Autor:
Howard A. Burris, Todd M. Bauer, Giuseppe Giaccone, Jan Baughman, Seock-Ah Im, Hua Li, Stanford J. Stewart, Jane B. Trepel, David A Carlin, Jeffrey L. Nordstrom, Yung-Jue Bang
Publikováno v:
Journal of Clinical Oncology. 31:3004-3004
3004 Background: The anti-HER2 MAb, trastuzumab (H), has proven effective for HER2+ breast cancer (BC) and gastroesophageal cancer (GEC). H’s mechanism of action is incompletely understood, but evidence indicates ADCC is important. MGAH22 is an Fc-