Zobrazeno 1 - 2
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pro vyhledávání: '"Lu MC"'
Publikováno v:
Cytokines and inflammatory mediators.
Background: Over-expression of membranous CD154 and soluble CD154 (sCD154) in T lymphocytes is important in pathogenesis of autoimmune diseases. PKC pathway induces sCD154 production through promoting shedding of membranous CD154. Objectives: Hydroxy
Publikováno v:
Clinical and Experimental Immunology. 168:78-86
Summary Abnormal Ca2+-mediated signalling contributes to the pathogenesis of rheumatoid arthritis (RA). However, the potential implication of calcium channel blocker in RA remained unknown. We hypothesized that nifedipine, an L-type calcium channel b