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Publikováno v:
Current Drug Safety. 16:259-263
Background: Colistin utilization has gradually increased worldwide with the rising of multidrug-resistant (MDR) gram-negative bacilli despite its nephrotoxicity. Lipid emulsion (LE) is widely used for the toxic overdose treatment of various drugs. Ob
Autor:
Moncef Fekih, Emna Gaïes, Hammami Mohamed Bassem, Ridha Ben Ali, Michelle-Véronique Elmay, Israa Dahmani, Sihem El Aïdli, Dorra Ben Said, Achraf Chedly
Publikováno v:
Drug and Chemical Toxicology. 45:2594-2600
Isoniazid (INH), being the first-line drug used as an anti-tuberculosis drug, is known to be associated with physiological deteriorations including hepatic and neurologic disturbances. This study was aimed at biochemical and behavioral characterizati
Autor:
Verónica Sanchez, Xavier Nadal, Ximena López Hill, Cecilia Scorza, Jessika Urbanavicius, José Pedro Prieto
Publikováno v:
Neurotoxicity Research. 38:478-486
In the last years, clinical and preclinical researchers have increased their interest in non-psychotomimetic cannabinoids, like cannabidiol (CBD), as a strategy for treating psychostimulant use disorders. However, there are discrepancies in the pharm
Publikováno v:
Pharmacol Biochem Behav
These experiments examined whether morphine and cocaine alter the balance between hippocampal and striatal memory systems measured long after drug exposure. Male rats received injections of morphine (5 mg/kg), cocaine (20 mg/kg), or saline for five c
Autor:
Marko Vasić, Csenger Kovácsházi, Marija Kosić, Vladislav Pajović, Gábor B. Brenner, Zoltán Giricz, Péter Ferdinandy, Dragana Bajic, Ljiljana Đukić, Nina Japundžić-Žigon
Publikováno v:
Toxicology and applied pharmacology. 423
Cardiomyopathy resistant to treatment is the most serious adverse effect of doxorubicin (dox). The mechanisms of dox-induced cardiomyopathy (DCM) have been extensively studied in dilated forms of DCM. However, efficient treatment did not emerge. The
Autor:
Jacob T. Krug, Matthew S. Mayes, Kathy Ayala, Aaron Ettenberg, Adam K. Klein, Erin M. Purvis, Lisette Collins, Matthew P. A. Fisher
Publikováno v:
Pharmacology Biochemistry and Behavior. 179:150-155
Bipolar illness is characterized by periods of “mania” — high energy, irritability, and increased psychomotor activation. While the neurobiological investigation of mania has been limited by the lack of reliable animal models, researchers have
Publikováno v:
Pharmacology Biochemistry and Behavior. 179:89-97
The Gateway Hypothesis is based on epidemiological data and states there is a progression of drug use from use of a softer drug (e.g., nicotine) to use of a harder drug (e.g., morphine). It has been suggested that this sequence is causal and is relev
Publikováno v:
Alcohol. 71:5-13
Clinical studies have shown a positive correlation between novelty-seeking behavior and the susceptibility to consume drugs of abuse. Although several animal studies have demonstrated this correlation with psychostimulants or morphine, studies with a
Sex differences in the discriminative stimulus characteristics of a morphine occasion setter in rats
Publikováno v:
Pharmacology, biochemistry, and behavior. 205
The current study investigated whether the stimulus effects of morphine can function as a positive and negative feature in a Pavlovian occasion setting drug discrimination preparation in male and female rats. Sprague-Dawley rats were assigned to a fe
Publikováno v:
Alcohol
The identification and characterization of variables that influence “liking” and enhance vulnerability to repeated alcohol use are vital to understanding and treating alcohol use disorders. In the current study, we explore the influence of rearin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc73156bad17f91368e3a7a9036d1807
https://europepmc.org/articles/PMC7722211/
https://europepmc.org/articles/PMC7722211/