Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Yuji Ikegaya"'
Publikováno v:
Biological and Pharmaceutical Bulletin. 44:789-797
Sleep curtailment negatively affects cardiac activities and thus should be ameliorated by pharmacological methods. One of the therapeutic targets is melatonin receptors, which tune circadian rhythms. Ramelteon, a melatonin MT1/MT2 receptor agonist, h
Publikováno v:
Journal of Pharmacological Sciences, Vol 145, Iss 1, Pp 97-104 (2021)
Sleep disorders adversely affect daily activities and cause physiological and psychiatric problems. The shortcomings of benzodiazepine hypnotics have led to the development of ramelteon, a melatonin MT1 and MT2 agonist. Although the sleep-promoting e
Publikováno v:
Asian Journal of Animal Sciences. 15:27-34
Publikováno v:
Journal of Pharmacological Sciences, Vol 144, Iss 4, Pp 212-217 (2020)
The hippocampus is a brain region well-known to exhibit structural and functional changes in temporal lobe epilepsy. Studies analyzing the brains of patients with epilepsy and those from animal models of epilepsy have revealed that microglia are exce
Autor:
Keisuke Toyama, Masanobu Kano, Shigeru Shinomoto, Yuji Ikegaya, Miki Hashizume, Masa aki Sato, Tomoe Ishikawa, Shinichiro Tsutsumi, Mitsuo Kawato, Huu Hoang, Kazuo Kitamura
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Scientific Reports
Scientific Reports
Two-photon imaging is a major recording technique used in neuroscience. However, it suffers from several limitations, including a low sampling rate, the nonlinearity of calcium responses, the slow dynamics of calcium dyes and a low SNR, all of which
Publikováno v:
Biological and Pharmaceutical Bulletin. 43:1356-1360
Polyherbal medicines are composed of multiple herbs and have traditionally been used in East Asian countries for the remedy of physiological symptoms. Although the effects of polyherbal formulations have been investigated at the molecular and behavio
Publikováno v:
Neuropsychopharmacology Reports
Background Status epilepticus‐induced hippocampal neuronal death, astrogliosis, and the activation of microglia are common pathological changes in mesial temporal lobe epilepsy (mTLE) with resistance to antiepileptic drugs. Neuronal death in mTLE g
Autor:
Tetsuya Sakaguchi, Mototsugu Sato, Asako Noguchi, Nobuyoshi Matsumoto, Yuji Ikegaya, Hide Aikawa
Publikováno v:
Neuroscience Research. 148:61-65
The behavioral state of animals is essential information for functional recordings of neuronal activity ; practically, the exact timing when animals recover from anesthesia is important information. Recordings of cortical local field potentials and d
Publikováno v:
Science Advances
Science Advances, Vol. 7, no.48 (2021)
Science Advances, Vol. 7, no.48 (2021)
Description
Hyperthermia mediates social defeat stress–induced impairment of adult neurogenesis.
Social stress impairs hippocampal neurogenesis and causes psychiatric disorders such as depression. Recent studies have highlighted the signi
Hyperthermia mediates social defeat stress–induced impairment of adult neurogenesis.
Social stress impairs hippocampal neurogenesis and causes psychiatric disorders such as depression. Recent studies have highlighted the signi
Autor:
Daigo Ochiai, Yasue Mitsukura, Yuji Ikegaya, Satoru Ikenoue, Masato Yasui, Yoshifumi Kasuga, Motoshige Sato, Hiroko Yamamoto, Mamoru Tanaka, Jun Ogasawara
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Cardiotocography records fetal heart rates and their temporal relationship to uterine contractions. To identify high risk fetuses, obstetricians inspect cardiotocograms (CTGs) by eye. Therefore, CTG traces are often interpreted differently among obst