Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Wilbert B. Copeland"'
Autor:
Brian Fox, Ethan G. Thompson, Greg Pietz, Kathryn Newhall, Wilbert B. Copeland, Mary H. Young, Elizabeth Whalen
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports
Scientific Reports
This study sought to understand how the programmed death ligand 1 (PD-L1) inhibitor durvalumab and the immunomodulatory agent pomalidomide regulate immune cell activation and function in patients with relapsed/refractory (RR) multiple myeloma (MM). I
Autor:
Amrit P. Singh, Frank Schmitz, Adam Z. Rosenthal, Madhav V. Dhodapkar, Antje Hoering, Daisy Alapat, Yan Ren, Maurizio Zangari, Kelsie Smith, Samuel A. Danziger, Jake Gockley, Andrew Dervan, Alexander V. Ratushny, Mark McConnell, Robert M. Hershberg, Suzana Couto, Brian A Walker, Faith E. Davies, Alison Fitch, Wilbert B. Copeland, Gareth J. Morgan, Bart Barlogie, Phil Farmer, David J. Reiss, Brian Fox, Mary H. Young, Frits van Rhee, Cody Ashby, Katie Newhall, Nathan Petty, Michael A Bauer, Robert Z. Orlowski, Matthew Trotter
Publikováno v:
PLoS Medicine
PLoS Medicine, Vol 17, Iss 11, p e1003323 (2020)
PLoS Medicine, Vol 17, Iss 11, p e1003323 (2020)
Background The tumor microenvironment (TME) is increasingly appreciated as an important determinant of cancer outcome, including in multiple myeloma (MM). However, most myeloma microenvironment studies have been based on bone marrow (BM) aspirates, w
Autor:
Amer M. Zeidan, Vanessa E. Gray, Tim O'Connor, Wilbert B. Copeland, Alessandro Previtali, James D. Cavenagh, Lewis R. Silverman, Mar Tormo, Shelonitda Rose, David Taussig, C.L. Beach, Isaac Boss, Maria Teresa Voso
Publikováno v:
Blood. 134:829-829
Background: Loss of immune surveillance, mediated through immune checkpoint (ICP) interactions, is thought to be a key step in the development of cancers including AML and HR-MDS. AZA is a standard therapy for pts with AML who are unfit for IC and fo
Autor:
Vitalina Komashko, Amit Agarwal, Frank Schmitz, Kathryn Newhall, Brian Fox, Wilbert B. Copeland, Ethan G. Thompson, Lauren Buchholz, Mark Tometsko, Elizabeth Whalen, Justine Dell’Aringa, Greg E. Pietz, Teresa Foy
Publikováno v:
Blood. 132:3161-3161
BACKGROUND: Loss of immune surveillance is critical in the pathogenesis of multiple myeloma (MM) and the progression from smoldering to symptomatic MM. To date, no clear efficacy signal has been observed with programmed-death 1 and programmed death l
Autor:
Alexander V. Ratushny, Rob Hershberg, Mary Young, Faith E. Davies, Antje Hoering, Frits van Rhee, Adam Rosenthal, Gareth J. Morgan, Matthew Trotter, Bart Barlogie, Brian A Walker, Maurizio Zangari, Mark McConnell, Brian Fox, Katie Newhall, Jake Gockley, Andrew Dervan, Nathan Petty, Michael A Bauer, Wilbert B. Copeland, Samuel A. Danziger, Cody Ashby, Alison Fitch, David J. Reiss, Frank Schmitz, Phil Farmer
Publikováno v:
Blood. 132:1882-1882
Introduction The multiple myeloma (MM) tumor microenvironment (TME) strongly influences patient outcomes as evidenced by the success of immunomodulatory therapies. To develop precision immunotherapeutic approaches, it is essential to identify and enu
Autor:
Jake Gockley, Andrew Dervan, Teri Foy, Brian A Walker, Mark McConnell, Alison Fitch, David J. Reiss, Gareth J. Morgan, Frank Schmitz, Samuel A. Danziger, Sarah K. Johnson, Katie Newhall, Alexander V. Ratushny, Robert M. Hershberg, Wilbert B. Copeland, Mary H. Young
Publikováno v:
Blood. 132:243-243
Introduction The multistep progression of multiple myeloma from a normal plasma cell to a system with the features of invasive cancer provides a unique opportunity to understand the co-evolution of the malignant clone within its microenvironment. Und
Autor:
Sean C. Sleight, Deepak Chandran, Bryan Bartley, Costas D. Maranas, Herbert M. Sauro, Kyung Hyuk Kim, Michal Galdzicki, Wilbert B. Copeland
A great variety of software applications are now employed in the metabolic engineering field. These applications have been created to support a wide range of experimental and analysis techniques. Computational tools are utilized throughout the metabo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e273ad031557c1fa55884f6652cefce4
https://europepmc.org/articles/PMC3361690/
https://europepmc.org/articles/PMC3361690/