Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Taru, Tukiainen"'
Autor:
Tiinamaija Tuomi, Taru Tukiainen, Sanni Ruotsalainen, Ari Ahola-Olli, Mika Kähönen, Mars Nt, Leevi Lehtonen, O T Raitakari, Jaakko T. Leinonen, Samuli Ripatti, Terho Lehtimäki, Mark J. Daly, Matti Pirinen
Testosterone (T) is linked with diverse characteristics of human health, yet, whether these associations reflect correlation or causation remains debated. Here, we provide a broad perspective on the role of T on complex diseases in both sexes leverag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::420e68f0a3ee3e863d8c1f86038ce5e8
https://doi.org/10.1101/2021.04.23.21255981
https://doi.org/10.1101/2021.04.23.21255981
Autor:
Nelson B. Freimer, Sanni Söderlund, Ida Surakka, Veikko Salomaa, Priit Palta, Samuli Ripatti, Joel T. Rämö, Nina Mars, Aarno Palotie, Pietari Ripatti, Elisabeth Widen, Taru Tukiainen, FinnGen, Tuomo Kiiskinen, Jake Lin, Aki S. Havulinna, Matti Pirinen, Christian Benner, Marja-Riitta Taskinen, Yu Fu
Publikováno v:
Circulation. Genomic and Precision Medicine
Supplemental Digital Content is available in the text.
Background: Hyperlipidemia is a highly heritable risk factor for coronary artery disease (CAD). While monogenic familial hypercholesterolemia associates with severely increased CAD risk, it
Background: Hyperlipidemia is a highly heritable risk factor for coronary artery disease (CAD). While monogenic familial hypercholesterolemia associates with severely increased CAD risk, it
Autor:
Stefan Blankenberg, Johannes Kettunen, Terho Lehtimäki, Mika Kähönen, Tanja Zeller, Kati Kristiansson, Aki S. Havulinna, Antti Jula, Taru Tukiainen, Veikko Salomaa, Markus Perola, Perttu Salo, Johan G. Eriksson, Minna Männikkö, Olli T. Raitakari
Publikováno v:
Circulation. Cardiovascular Genetics
Supplemental Digital Content is available in the text.
Background— Cardiomyocytes secrete atrial natriuretic peptide (ANP) and B-type natriuretic peptide (BNP) in response to mechanical stretching, making them useful clinical biomarkers of car
Background— Cardiomyocytes secrete atrial natriuretic peptide (ANP) and B-type natriuretic peptide (BNP) in response to mechanical stretching, making them useful clinical biomarkers of car
Autor:
Sean G. Byars, Samuli Ripatti, Le Shu, Yuqi Zhao, Zeyneb Kurt, Ville-Petteri Mäkinen, Bin Zhang, Michael Inouye, Xia Yang, Johannes Kettunen, Taru Tukiainen
Mergeomics is a computational pipeline (http://mergeomics.research.idre.ucla.edu/Download/Package/) that integrates multidimensional omics-disease associations, functional genomics, canonical pathways and gene-gene interaction networks to generate me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a87dcde55a1d122a470b698cbf07309a
https://doi.org/10.1101/036012
https://doi.org/10.1101/036012
Autor:
Mehran Taherian, Debra Bradbury, Emmanouil T. Dermitzakis, Manuel A. Rivas, Deborah C. Mash, Ayellet V. Segrè, Luan Lin, Ping Guan, Kimberly Ramsey, Mary Barcus, Deborah Colantuoni, Xiaoquan Wen, Julian Maller, Ferran Reverter, Laura A. Siminoff, Bryan Gillard, Dana R. Valley, Gen Li, Jeffery P. Struewing, Philip A. Branton, Roderic Guigó, Nancy Roche, Charles Shive, Christopher Choi, Johnell Fleming, Timothée Flutre, Latarsha J. Carithers, Taylor Young, Anuar Konkashbaev, Matthew Stephens, Daniel G. MacArthur, Rick Hasz, Mark I. McCarthy, Joel N. Hirschhorn, Sara Mostafavi, Lucas D. Ward, Amanda Brown, Ki Sung Um, Manolis Kellis, Robin Burges, Eric R. Gamazon, Heather M. Traino, Gary F. Temple, Karna Robinson, Leslie H. Sobin, Daphne Koller, Halit Ongen, Bernadette Mestichelli, John T. Lonsdale, Kimberly M. Valentino, Ellen Gelfand, David Tabor, Taru Tukiainen, Mike Salvatore, Gary Walters, Susan L. Sullivan, Jason Bridge, Carolyn C. Compton, Kenneth W. Hambright, Joy T. Boyer, Bin Zhang, Anita H. Undale, Michael Sammeth, Helen M. Moore, Nancy J. Cox, Andrey A. Shabalin, Kenyon Erickson, Nicole C. Lockhart, Gad Getz, Pushpa Hariharan, Benjamin Iriarte, Jakob M. Goldmann, Pouya Kheradpour, John Syron, Jimmie B. Vaught, Jun Zhu, Hae Kyung Im, Jean Monlong, John Seleski, Marta Melé, Edmund Lo, Yvonne Marcus, Pedro G. Ferreira, Stephen A. Buia, Liqun Qi, Greg E. Korzeniewski, Michael T. Moser, Ivan Rusyn, Andrew B. Nobel, Casandra A. Trowbridge, Timothy J. Sullivan, Chunrong Lu, Barbara A. Foster, Laura Barker, Jun Liu, Shenpei Wu, Anna M. Smith, Joanne P. Demchok, Dan L. Nicolae, Jeffrey A. Thomas, Jonathan K. Pritchard, Sherilyn Sawyer, Fred A. Wright, Wendy Winckler, Angela Britton, Zhidong Tu, Jorge Tejada, David S. DeLuca, Yi-Hui Zhou, Roger Little, Jeffrey McLean, Simona Volpi, Tõnu Esko, Kristin G. Ardlie, Monkol Lek, Daniel C. Rohrer, Susan E. Koester, Harold Magazine, Mark Miklos, Quan Long, Jialiang Yang, Cameron D. Palmer, Maghboeba Mosavel, Scott D. Jewell, Tuuli Lappalainen, Alexis Battle, Ellen Karasik, Margaret J. Basile, Saboor Shad, Denee Tidwell, Yan Meng, Chana A. Rabiner, Tao Huang
Publikováno v:
Science
Science, American Association for the Advancement of Science, 2015, 348 (6235), pp.648-660. ⟨10.1126/science.1262110⟩
Science, American Association for the Advancement of Science, 2015, 348 (6235), pp.648-660. ⟨10.1126/science.1262110⟩
UMR AGAP - équipe DAAV (Diversité, adaptation et amélioration de la vigne)139 auteurs : Ardlie KG, Deluca DS, Segrè AV, Sullivan TJ, Young TR, Gelfand ET, Trowbridge CA, Maller JB, Tukiainen T, Lek M, Ward LD, Kheradpour P, Iriarte B, Meng Y, Pal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c4415d157f3f793e92cd1f5af60e0bb
https://hal.archives-ouvertes.fr/hal-01157916
https://hal.archives-ouvertes.fr/hal-01157916
Autor:
Pasi Soininen, Markku J. Savolainen, M. Ala-Korpela, A.J. Kangas, Tuire Salonurmi, Peter Würtz, Taru Tukiainen, Marjo-Riitta Järvelin
Publikováno v:
Atherosclerosis Supplements. 11:23
Autor:
Matteo Pellegrini, Xia Yang, Zeyneb Kurt, Johannes Kettunen, Samuli Ripatti, Yuqi Zhao, Aldons J. Lusis, Sean G. Byars, Michael Inouye, Taru Tukiainen, Ville-Petteri Mäkinen, Luz D. Orozco, Bin Zhang, Le Shu
Publikováno v:
BMC genomics, vol 17, iss 1
BMC Genomics
BMC Genomics
Background Complex diseases are characterized by multiple subtle perturbations to biological processes. New omics platforms can detect these perturbations, but translating the diverse molecular and statistical information into testable mechanistic hy