Zobrazeno 1 - 10
of 3 531
pro vyhledávání: '"Mice, Inbred C3H"'
Autor:
Takashi Shimokawa, Takashi Imai, Akihisa Takahashi, Tsuguhide Takeshima, Hiromi Otsuka, Ken Ando, Liqiu Ma, Kazuhiro Kakimi, Yoshimitsu Sakamoto, Daniel K. Ebner, Hidetoshi Fujita
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 112:780-789
Purpose: The goal of this study is to clarify the underlying mechanisms of metastasis suppression by CiDC (carbon-ion radiotherapy (CIRT) combined with immature dendritic cell (iDC) immunotherapy), which was previously shown to significantly suppress
Autor:
Adam Williams, Stephanie C. Eisenbarth, Lan Xu, Biyan Zhang, Lauren L. Long, Jake A. Gertie, Laura R. Hoyt, Uthaman Gowthaman, Xiangyun Yin, Elise G. Liu, Arielle Soldatenko
Publikováno v:
J Allergy Clin Immunol
Background The etiology of food allergy is poorly understood; mouse models are powerful systems to discover immunologic pathways driving allergic disease. C3H/HeJ mice are a widely used model for the study of peanut allergy because, unlike C57BL/6 or
Publikováno v:
Japanese Journal of Radiology. 40:466-475
PURPOSE Although the mechanism of onset and progression of radiation-induced fibrosis (RIF) has been studied, most studies to date have focused on pulmonary fibrosis. There are few studies on murine RIF in the skeletal muscle, and the pathogenic mech
Publikováno v:
Am J Transplant
Chronic rejection is among the most pressing clinical challenges in solid organ transplantation. Interestingly, in a mouse model of heterotopic heart transplantation, antibody-dependent, natural killer (NK) cell-mediated chronic cardiac allograft vas
Autor:
Toshinori Tsukanishi, Tsukasa Yonemoto, Hiroto Kamoda, Hideyuki Kinoshita, Takeshi Ishii, Yoko Hagiwara, Osamu Shimozato, Seiji Ohtori
Publikováno v:
Anticancer Research. 41:4947-4955
Background/aim Auranofin (AUR), a thioredoxin reductase (TXNRD) inhibitor, shows anticancer activity against several cancers. This study investigated the effects of AUR on the local progression and pulmonary metastasis of osteosarcoma (OS). Materials
Autor:
Kazuhisa Uchiyama, Emi Yasuda, Yuro Shibayama, Takahiro Kubota, Nobuhiko Tanigawa, Ryotaro Yoshida, Michihiro Hayashi, Yoshinobu Hirose, Hidenori Yamana
Publikováno v:
Journal of Interferon & Cytokine Research. 41:310-318
Graft-versus-host disease (GVHD) is a physiological response of the graft to allogeneic hosts. However, the effector cells, affected organ(s), and cytokines in the GVHD remain controversially discussed, without having determined a particular cytotoxi
Publikováno v:
Molecular Neurobiology
Dolutegravir (DTG) is a first-line antiretroviral drug (ARV) used in combination therapy for the treatment of human immunodeficiency virus type-1 (HIV-1) infection. The drug is effective, safe, and well tolerated. Nonetheless, concerns have recently
Autor:
Kiyomi Ito, Yoshiaki Yamagishi, Taiki Akashi, Shohei Kobayashi, Toshiyuki Kudo, Takeaki Kawakami, Hideyo Takahashi, Yasuhiro Sato, Masafumi Oyumi, Kosho Makino, Masakazu Mimaki, Hitomi Goda, Mitsutoshi Munakata, Hiroko Kodama, Toshiro Fukami, Kazuki Takahashi, Yusuke Sakamoto
Publikováno v:
Pharmaceutical Research. 38:1335-1344
Menkes disease is a rare hereditary disease in which systemic deficiency of copper due to mutation of the ATP7A gene causes severe neurodegenerative disorders. The present parenteral drugs have limited efficacy, so there is a need for an efficacious
Autor:
Wim E. Hennink, Linette E M Willemsen, Cornelus F. van Nostrum, Johan Garssen, Suzan Thijssen, Mengshan Liu
Publikováno v:
Clinical & Experimental Allergy. 52:137-148
BACKGROUND Two to four percentage of infants are affected by cow's milk allergy (CMA), which persists in 20% of cases. Intervention approaches using early oral exposure to cow's milk protein or hydrolysed cow's milk formula are being studied for CMA
Autor:
Yu Kawanishi, Takaaki Aratake, Takahito Nakajo, Youichirou Higashi, Naoki Fukui, Tetsuya Ueba, Koichi Honke, Toshio Yawata, Tatsuyuki Yamashita
Publikováno v:
Journal of Neurosurgery. 134:1772-1782
OBJECTIVE Glioma stem cells (GSCs) are responsible for tumor initiation, therapeutic resistance, and recurrence. CD146 is mainly expressed in dividing GSCs and regulates cell cycle progression. However, the evaluation of the efficacy of targeted ther