Zobrazeno 1 - 10
of 40
pro vyhledávání: '"David L. Huso"'
Autor:
Alfred Morgenstern, Zhe Zhang, Takahiro Yoshida, Hong Song, Sunju Park, Han Liangfeng, Charles Zhu, Saraswati Sukumar, Frank Bruchertseifer, Kideok Jin, George Sgouros, David L. Huso
Publikováno v:
Oncotarget
The standard treatment for ductal carcinoma in situ (DCIS) of the breast is surgical resection, followed by radiation. Here, we tested localized therapy of DCIS in mice using the immunoconjugate 225Ac linked-trastuzumab delivered through the intraduc
Autor:
Liangfeng Han, Helen Sadik, Yolanda M.N. Foster, Duojia Pan, Angela Brodie, Zhe Zhang, Syed Z. Ali, Peter Ordentlich, David L. Huso, Christina Adams, Roisin M. Connolly, Soonweng Cho, Vered Stearns, Nguyen Nguyen, Preethi Korangath, Kideok Jin, Saraswati Sukumar, Xian C. Zhou, Qian Chen, Vanessa F. Merino
Publikováno v:
Cancer Research. 76:2013-2024
Efforts to induce the differentiation of cancer stem cells through treatment with all-trans retinoic acid (ATRA) have yielded limited success, partially due to the epigenetic silencing of the retinoic acid receptor (RAR)-β. The histone deacetylase i
Autor:
Michael Koo, James Turkson, David L. Huso, Tait Huso, Patrick T. Gunning, Lingling Xian, Guosheng Liu, Brent D. G. Page, Amy Belton, Li Z. Luo, Linda M.S. Resar
Publikováno v:
Leukemia & Lymphoma. 57:2681-2684
Despite dramatic improvements in treatment and survival, acute lymphoid malignancies remain the leading cause of death in children with cancer and a highly lethal malignancy in adults.[1] Acute lym...
Autor:
Venkata S. Pendyala, James J. Potter, Lahari Koganti, Svetlana Lutsenko, David L. Huso, Uta Merle, Joseph A. Hankin, Esteban Mezey, James P. Hamilton, Abigael Muchenditsi, Nan Yang, Dominik Huster, Christopher Mangels, Robert C. Murphy
Publikováno v:
Hepatology. 63:1828-1841
UNLABELLED Wilson disease (WD) is a hepatoneurological disorder caused by mutations in the copper-transporter, ATP7B. Copper accumulation in the liver is a hallmark of WD. Current therapy is based on copper chelation, which decreases the manifestatio
Autor:
Nicholas Huso, Yichun Chen, Rustam Bagirzadeh, David L. Huso, Jennifer P Habashi, Tyler J. Creamer, Harry C. Dietz, Maurice Manning, Caitlin J. Bowen, Graham Rykiel, Djahida Bedja, Elena Gallo MacFarlane
Publikováno v:
Sci Transl Med
Women with Marfan syndrome (MFS) are at high risk for pregnancy-associated aortic dissection. Pathogenic models that singularly invoke hemodynamic stress are difficult to reconcile with predominant postnatal occurrence of aortic tear, often occurring
Autor:
David L. Huso, Stuart W. Smith, Hannah Louise Morris, Caroline O. S. Savage, Amy J. Naylor, Christopher D. Buckley, Adam P. Croft, Clare M. Isacke
Publikováno v:
Nephron. 131:265-277
Background: Tissue fibrosis and microvascular rarefaction are hallmarks of progressive renal disease. CD248 is a transmembrane glycoprotein expressed by key effector cells within the stroma of fibrotic kidneys including pericytes, myofibroblasts and
Autor:
Elizabeth A. Ihms, Larry Gainsburg, David L. Huso, Jan Fritz, Rebecca A. Krimins, Dara L. Kraitchman, Patrick R. Gavin
Publikováno v:
Journal of the American Veterinary Medical Association. 250(7)
CASE DESCRIPTION A 9-year-old spayed female Rottweiler with hind limb ataxia was examined because of anorexia and an acute onset of hind limb paresis. CLINICAL FINDINGS Neurologic evaluation revealed hind limb ataxia and symmetric paraparesis with bi
Autor:
Gopala K. Rangan, David Liuwantara, Kristina G. Schwensen, Terry Watnick, Michelle H. T. Ta, David L Huso
To determine the temporal expression and pattern of Rel/nuclear factor (NF)-κB proteins in renal tissue in polycystic kidney disease (PKD).The renal expression of Rel/NF-κB proteins was determined by immunohistochemistry, immunofluorescence and imm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c88f8d74163eb743fa01db9ed4d622c
https://europepmc.org/articles/PMC4936341/
https://europepmc.org/articles/PMC4936341/
Autor:
Robert A. Casero, Franck Housseau, Cynthia L. Sears, Sara W. Van Meerbeke, David L. Huso, Christina E. DeStefano Shields, Hao Wang, Heather M. O'Hagan
BACKGROUND Chronic inflammation and composition of the colon microbiota have been associated with colorectal cancer in humans. The human commensal enterotoxigenic Bacteroides fragilis (ETBF) is linked to both inflammatory bowel disease and colorectal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b62ad187a1d4759ea3cb2aae9338cc5b
https://europepmc.org/articles/PMC4907405/
https://europepmc.org/articles/PMC4907405/
Autor:
Jamunarani Vadivelu, David L. Huso, Ausama A. Malik, Elizabeth C. Wick, Kellie N. Smith, Jane W. Wanyiri, Drew M. Pardoll, Cynthia L. Sears, Shaoguang Wu, Sudipto Ganguly, Nicolas J. Llosa, Ada Tam, Hongni Fan, Franck Housseau, Sara W. Van Meerbeke, April Camilla Roslani, Xinqun Wu, Thevambiga Iyadorai
IL17-producing Th17 cells, generated through a STAT3-dependent mechanism, have been shown to promote carcinogenesis in many systems, including microbe-driven colon cancer. Additional sources of IL17, such as γδ T cells, become available under infla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87717b07cd19af2a98a001e5904f8520
https://europepmc.org/articles/PMC4873376/
https://europepmc.org/articles/PMC4873376/