Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Danielle M. Friedrichsen"'
Autor:
Erika M. Kwon, Laura McIntosh, Kerry Deutsch, Marta Janer, Leroy Hood, Danielle M. Friedrichsen-Karyadi, Janet L. Stanford, Bo Johanneson, Elaine A. Ostrander, Lori Iwasaki
Publikováno v:
The Prostate. 67:732-742
BACKGROUND. The Seattle-based PROGRESS study was started in 1995 to ascertain hereditary prostate cancer (HPC) families for studies of genetic susceptibility. Subsequent studies by several research groups, including our own, suggest that HPC is a gen
Autor:
Lee Hood, Kerry Deutsch, Brandon L. Pierce, Melissa A. Austin, Elaine A. Ostrander, Laura McIntosh, Danielle M. Friedrichsen-Karyadi, Janet L. Stanford
Publikováno v:
The Prostate. 67:410-415
BACKGROUND Prostate cancer is a genetically heterogeneous disease. Using the occurrence of other cancers in hereditary prostate cancer (HPC) families is a promising strategy for developing genetically homogeneous data sets that can enhance the abilit
Autor:
Lori Iwasaki, Danielle M. Friedrichsen, Ruth Etzioni, Leah P. Sabacan, Janet L. Stanford, Elaine A. Ostrander, Jainfen Shu, Mariela C. Humphrey, Sarah Hawley
Publikováno v:
The Prostate. 65:44-51
BACKGROUND Insulin-like growth factor-I (IGF-I) is a potent mitogen for both normal and malignant prostate epithelial cells. The majority of circulating IGF-I is bound in a complex with IGF binding protein-3 (IGFBP-3), which in turn limits IGF-I bioa
Autor:
Mette A. Peters, Mahesh B. Keitheri Cheteri, Lori Iwasaki, Ziding Feng, Danielle M. Friedrichsen, Janet L. Stanford, Mariela C. Langlois, Elaine A. Ostrander
Publikováno v:
The Prostate. 59:409-418
BACKGROUND Vitamin D is a steroid hormone that is thought to play a role in the etiology and progression of prostate cancer. Hormone activity requires binding to the vitamin D receptor (VDR), which contains several genetic polymorphisms that have bee
Autor:
Russ Welti, Kerry Deutsch, Leroy Hood, Marta Janer, Elaine A. Ostrander, Hawkins B. DeFrance, Gail P. Jarvik, Lori Iwasaki, Mette A. Peters, Ellen L. Goode, Sarah Li, Michael D. Badzioch, Danielle M. Friedrichsen, Janet L. Stanford, Suzanne Kolb
Publikováno v:
The Prostate. 57:309-319
Hereditary prostate cancer (HPC) is a genetically heterogeneous disease, complicating efforts to map and clone susceptibility loci. We have used stratification of a large dataset of 254 HPC families in an effort to improve power to detect HPC loci an
Autor:
Danielle M. Friedrichsen, Janet R. Daling, Mariela C. Humphrey, Brian L. Strom, Nicola M. Suter, Jill A. McDonald, David R. Doody, Robert Spirtas, Polly A. Marchbanks, Ralph J. Coates, Ronald T. Burkman, Linda K. Weiss, Sandra A. Norman, Elaine A. Ostrander, Li Hsu, Jennifer Madeoy, Kathleen E. Malone, Dennis Deapen, Suzanne G. Folger, Michael S. Simon, Giske Ursin, Leslie Bernstein
Publikováno v:
Cancer research. 66(16)
Although well studied in families at high-risk, the roles of mutations in the BRCA1 and BRCA2 genes are poorly understood in breast cancers in the general population, particularly in Black women and in age groups outside of the very young. We examine
Autor:
Erin E. Carlson, Marta Janer, Daniel J. Schaid, Janet L. Stanford, Danielle M. Friedrichsen, Suzanne Kolb, Lee Hood, Shannon K. McDonnell, Kerry Deutsch, Elaine A. Ostrander
Publikováno v:
The Prostate. 66(3)
BACKGROUND Prostate cancer is a heterogeneous disease, both genetically and phenotypically. Linkage studies attempting to map genes for hereditary prostate cancer (HPC) have proved challenging, and one potential problem contributing to this challenge