Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Cindy Delbrook"'
Autor:
David F. Stroncek, Pamela L. Wolters, Terry J. Fry, Maryalice Stetler-Stevenson, Haneen Shalabi, Cindy Delbrook, Crystal L. Mackall, Staci Martin, Nirali N. Shah, Daniel W. Lee, Eva H. Baker, Seth M. Steinberg, Bonnie Yates, Constance M. Yuan
Publikováno v:
J Clin Oncol
PURPOSE CD19 chimeric antigen receptor (CD19-CAR) T cells induce high response rates in children and young adults (CAYAs) with B-cell acute lymphoblastic leukemia (B-ALL), but relapse rates are high. The role for allogeneic hematopoietic stem-cell tr
Autor:
Staci Martin, Maryalice Stetler-Stevenson, Sandhya R. Panch, Seth M. Steinberg, Steven L. Highfill, Haris Qureshi, Cindy Delbrook, Haiying Qin, Alina Dulau-Florea, Hao-Wei Wang, Crystal L. Mackall, Jianjian Jin, Constance M. Yuan, Lauren Little, Pamela L. Wolters, David F. Stroncek, Haneen Shalabi, Leah Hoffman, Dalia Salem, Terry J. Fry, Nirali N. Shah, Anusha Ponduri, Minh Tran, Bonnie Yates, Amanda K. Ombrello
Publikováno v:
J Clin Oncol
PURPOSE Patients with B-cell acute lymphoblastic leukemia who experience relapse after or are resistant to CD19-targeted immunotherapies have limited treatment options. Targeting CD22, an alternative B-cell antigen, represents an alternate strategy.
Autor:
Cindy Delbrook, Haneen Shalabi, Bonnie Yates, Dalia Salem, Diane Libert, Maryalice Stetler-Stevenson, Katherine E. Masih, Javed Khan, Jack F. Shern, Pallavi Galera, Terry J. Fry, Nirali N. Shah, Constance M. Yuan
Publikováno v:
Leukemia
Autor:
Kevin J. Curran, Nirali N. Shah, Steven A. Rosenberg, Marco L. Davila, Roisin E. O'Cearbhaill, Gary E. Archer, Jean Yuh Tang, Crystal L. Mackall, Richard P. Junghans, Michel Sadelain, Lisa Duffy, Kenneth Cornetta, Renier J. Brentjens, Rosie Kaplan, Hans-Peter Kiem, Steven A. Feldman, Isabelle Riviere, Cindy Delbrook, James N. Kochenderfer
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 10, Iss, Pp 371-378 (2018)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
Replication-competent retrovirus (RCR) is a safety concern for individuals treated with retroviral gene therapy. RCR detection assays are used to detect RCR in manufactured vector, transduced cell products infused into research subjects, and in the r
Autor:
Brandon M. Wiley, Amita Kulshreshtha, Bonnie Yates, Daniel W. Lee, Stanislav Sidenko, Haneen Shalabi, Julia W. Cohen, Nirali N. Shah, Cindy Delbrook, Crystal L. Mackall, Vandana Sachdev, Doug R Rosing
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
BackgroundChimeric antigen receptor (CAR) T-cell-associated cytokine release syndrome (CRS) may present with tachycardia, hemodynamic instability and reduced cardiac function. Pediatric CAR studies examining cardiac toxicity are limited.MethodsWe rep
Autor:
Nirali N. Shah, Mark J. Roth, Haneen Shalabi, Amita Kulshreshtha, Constance M. Yuan, Dalia A. Salem, Crystal L. Mackall, Alina Dulau-Florea, Terry J. Fry, Maryalice Stetler-Stevenson, Armando C. Filie, Alan S. Wayne, Daniel W. Lee, Joanne Derdak, Bonnie Yates, Gaurav K. Gupta, Cindy Delbrook
Publikováno v:
Pediatr Blood Cancer
Background Accurate disease detection is integral to risk stratification in B-cell acute lymphoblastic leukemia (ALL). The gold standard used to evaluate response in the United States includes morphologic evaluation and minimal residual disease (MRD)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72c89c2d44636318636e59063161f9bd
https://europepmc.org/articles/PMC7036332/
https://europepmc.org/articles/PMC7036332/
Autor:
Staci Martin, Robbie G. Majzner, Constance M. Yuan, Bonnie Yates, Jack F. Shern, Haneen Shalabi, Haiying Qin, David F. Stroncek, Marianna Sabatino, Terry J. Fry, Boro Dropulic, Cindy Delbrook, Yang Feng, Nirali N. Shah, Thomas J. Fountaine, Rimas J. Orentas, Daniel W. Lee, Crystal L. Mackall, Maryalice Stetler-Stevenson, Sneha Ramakrishna, Pamela L. Wolters, Dimiter S. Dimitrov, Ling Zhang, Sang M. Nguyen
Publikováno v:
Nature Medicine. 24:20-28
Chimeric antigen receptor (CAR) T cells targeting CD19 mediate potent effects in relapsed and/or refractory pre-B cell acute lymphoblastic leukemia (B-ALL), but antigen loss is a frequent cause of resistance to CD19-targeted immunotherapy. CD22 is al
Autor:
Terry J. Fry, Haiying Qin, Cindy Delbrook, Ashley K. Koegel, Anusha Ponduri, Maryalice Stetler-Stevenson, Nirali N. Shah, Mignon L. Loh, Bonnie Yates, Dalia Salem, Constance M. Yuan, Haneen Shalabi
Publikováno v:
ADVANCES IN CELL AND GENE THERAPY. 2
Autor:
Eli Kane, Marie Claire Roderick, Staci Martin, Daniel W. Lee, Nirali N. Shah, Kari Struemph, Cindy Delbrook, Terry J. Fry, Crystal L. Mackall, Pamela L. Wolters, Haneen Shalabi, Mary Anne Toledo-Tamula, Bonnie Yates
Neurotoxicity associated with CAR-T cell therapy can be life-threatening. With rapid development of CAR-T therapies, a systematic method is needed to identify and monitor symptoms of neurotoxicity, elucidate potential etiologies, and compare toxicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ddd097f65f1a686bb2854d871ecc08c
https://europepmc.org/articles/PMC6086728/
https://europepmc.org/articles/PMC6086728/
Autor:
Jedd D. Wolchok, Maya Lodish, Matthew Wright, Crystal L. Mackall, Donna Bernstein, Carlos Rodriguez-Galindo, Cindy Delbrook, Melinda S. Merchant, Leonard H. Wexler, Howard Streicher, Kristin Baird, Rachel Bishop
Publikováno v:
Clinical Cancer Research. 22:1364-1370
Purpose: Ipilimumab is a first-in-class immune checkpoint inhibitor approved for treatment of metastatic melanoma but not studied in children until this phase I protocol. Experimental Design: This study examined safety, pharmacokinetics, and immunoge