Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Basu, Bristi"'
Autor:
Ruth Riisnaes, Christina Guo, Priya Sriskandarajah, Maxime Chénard-Poirier, Jenny King, Samuel John Harris, Yuji Ishikawa, Emma Hall, Juanita Lopez, Anna Minchom, Nina Tunariu, Johann S. de Bono, Wen Xu, Suzanne Carreira, Anastasia Constantinidou, Alison Turner, Kiyohiko Nakai, Udai Banerji, Bristi Basu, Mariana Scaranti, Desamparados Roda, Laura Finneran, Irene Moreno Candilejo, Maria de Miguel, Mona Parmar, Martin Kaiser
Publikováno v:
The Lancet. Oncology
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname
Background CH5126766 (also known as VS-6766, and previously named R05126766), a novel MEK-pan-RAF inhibitor, has shown antitumour activity across various solid tumours; however, its initial development was limited by toxicity. We aimed to investigate
Autor:
Regina Schinner, Tim A. Labeur, Heinz-Josef Klümpen, Ron A. A. Mathôt, Peter Malfertheiner, Jens Ricke, Otto M. van Delden, Julia Mayerle, Holger Amthauer, Kerstin Schütte, Bristi Basu, R. Bart Takkenberg, Quincy Hofsink, Christiane K. Kuhl
Publikováno v:
Acta Oncologica, 59(9), 1028-1035. Informa Healthcare
Background: Sorafenib for advanced hepatocellular carcinoma (HCC) is dose adjusted by toxicity. Preliminary studies have suggested an association between plasma concentrations of sorafenib and its main metabolite (M2) and clinical outcomes. This stud
Autor:
Nagy A. Habib, Emilio Sanseviero, Madhava Pai, Debashis Sarker, Ayumi Hashimoto, Daniel H. Palmer, Mikael H. Sodergren, Vikash Reebye, Jeff Evans, Shahid A. Khan, Nina Raulf, Y.T. Ma, Andrew V. Kossenkov, Robert Habib, David J. Pinato, Ruth Plummer, Cheng E. Chee, John J. Rossi, Kai-Wen Huang, Naouel Elasri, Sheba Jarvis, Duncan Spalding, Jenni Vasara, Dmitry I. Gabrilovich, Bristi Basu, Adeline Reynaud, Mark Cobbold, Anna Martirosyan, Tim Meyer, Rohini Sharma, Pinelopi Andrikakou
Publikováno v:
Clin Cancer Res
Purpose: To evaluate the mechanisms of how therapeutic upregulation of the transcription factor, CCAAT/enhancer-binding protein alpha (C/EBPα), prevents tumor progression in patients with advanced hepatocellular carcinoma (HCC) and in different mous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8ca2967f716b56bccb65db914fa7bfa
https://www.repository.cam.ac.uk/handle/1810/349249
https://www.repository.cam.ac.uk/handle/1810/349249
Autor:
Manuel Delgado, Mar Lozano, Alejandro Forner, Bruno Sangro, Alessandro Granito, Margarita Sala, Monica Ronzoni, Giuseppe Cabibbo, Frederik J H Hoogwater, José Luis Lledó, Rosanna Villani, Alessandra Elvevi, Lorenza Rimassa, Juan Acevedo, Mariona Calvo, Mercedes Vergara, Sergio Muñoz-Martínez, Jean-Charles Nault, Juan C. Bandi, Markus Peck-Radosavljevic, Brandon M. Meyers, Marco Sanduzzi-Zamparelli, Rogerio Alves, Saleh A. Alqahtani, Alberto E. Muñoz, Sonia Pascual, Alberto Lué, Josepmaria Argemi, Beatriz Minguez, Henning Wege, Giovan Giuseppe Di Costanzo, David J. Pinato, Victor Sapena, Maria Guarino, Stefano Okolicsanyi, Vivianne Mello, Martina Gambato, Susanna Coll, Carlos Benítez, Dhanny Gomez, Christoph Roderburg, Peter R. Galle, Bristi Basu, Federico Piñero, Cassia Leal, Frank Tacke, Christie Perelló, Tudor Mocan, Massimiliano Salati, Helen L. Reeves, Jörg Trojan, Vincenzo Cardinale, Mohamed El Kassas, Tom Lüdde, John Bridgewater, Mário Reis Álvares-da-Silva, Anja Lachenmayer, Giovanni Brandi, Alex Vianey Callado França, Mohamed Bouattour, Tim Meyer, Gerda Elisabeth Villadsen, M. Varela, Jordi Bruix, Dalia Morales-Arraez, Carlos Rodríguez-Lope, Christian Toso, Wacław Hołówko, Philippe Merle, Manuel Romero-Gómez, Ignacio García-Juárez, Fernanda Branco, Gonzalo Sapisochin, Chiara Braconi, Emmanouil Giorgakis, Hidenori Toyoda, Lorraine Blaise, Ana María Matilla Peña, Andrea Casadei-Gardini, Leonardo G Da Fonseca, Alexander Siebenhüner, Maria Reig, Gustavo Pereira, Massimo Iavarone, Maria Margarita Anders
Publikováno v:
JHEP reports : innovation in hepatology, Vol. 3, No 3 (2021) P. 100260
Muñoz-Martínez, Sergio; Sapena, Victor; Forner, Alejandro; Nault, Jean-Charles; Sapisochin, Gonzalo; Rimassa, Lorenza; Sangro, Bruno; Bruix, Jordi; Sanduzzi-Zamparelli, Marco; Hołówko, Wacław; El Kassas, Mohamed; Mocan, Tudor; Bouattour, Mohamed; Merle, Philippe; Hoogwater, Frederik J H; Alqahtani, Saleh A; Reeves, Helen L; Pinato, David J; Giorgakis, Emmanouil; Meyer, Tim; ... (2021). Assessing the impact of COVID-19 on liver cancer management (CERO-19). JHEP reports, 3(3), p. 100260. Elsevier 10.1016/j.jhepr.2021.100260
JHEP Reports, Vol 3, Iss 3, Pp 100260-(2021)
JHEP reports : innovation in hepatology, 3(3):100260. Elsevier
Scopus
Muñoz-Martínez, S, Sapena, V, Forner, A, Nault, J C, Sapisochin, G, Rimassa, L, Sangro, B, Bruix, J, Sanduzzi-Zamparelli, M, Hołówko, W, El Kassas, M, Mocan, T, Bouattour, M, Merle, P, Hoogwater, F J H, Alqahtani, S A, Reeves, H L, Pinato, D J, Giorgakis, E, Meyer, T, Villadsen, G E, Wege, H, Salati, M, Mínguez, B, Di Costanzo, G G, Roderburg, C, Tacke, F, Varela, M, Galle, P R, Alvares-da-Silva, M R, Trojan, J, Bridgewater, J, Cabibbo, G, Toso, C, Lachenmayer, A, Casadei-Gardini, A, Toyoda, H, Lüdde, T, Villani, R, Matilla Peña, A M, Guedes Leal, C R, Ronzoni, M, Delgado, M, Perelló, C, Pascual, S, Lledó, J L, Argemi, J, Basu, B, da Fonseca, L, Acevedo, J, Siebenhüner, A R, Braconi, C, Meyers, B M, Granito, A, Sala, M, Rodríguez-Lope, C, Blaise, L, Romero-Gómez, M, Piñero, F, Gomez, D, Mello, V, Pinheiro Alves, R C, França, A, Branco, F, Brandi, G, Pereira, G, Coll, S, Guarino, M, Benítez, C, Anders, M M, Bandi, J C, Vergara, M, Calvo, M, Peck-Radosavljevic, M, García-Juárez, I, Cardinale, V, Lozano, M, Gambato, M, Okolicsanyi, S, Morales-Arraez, D, Elvevi, A, Muñoz, A E, Lué, A, Iavarone, M & Reig, M 2021, ' Assessing the impact of COVID-19 on liver cancer management (CERO-19) ', JHEP Reports, vol. 3, no. 3, 100260 . https://doi.org/10.1016/j.jhepr.2021.100260
JHEP Reports
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
Digital.CSIC. Repositorio Institucional del CSIC
Scientia
Muñoz-Martínez, Sergio; Sapena, Victor; Forner, Alejandro; Nault, Jean-Charles; Sapisochin, Gonzalo; Rimassa, Lorenza; Sangro, Bruno; Bruix, Jordi; Sanduzzi-Zamparelli, Marco; Hołówko, Wacław; El Kassas, Mohamed; Mocan, Tudor; Bouattour, Mohamed; Merle, Philippe; Hoogwater, Frederik J H; Alqahtani, Saleh A; Reeves, Helen L; Pinato, David J; Giorgakis, Emmanouil; Meyer, Tim; ... (2021). Assessing the impact of COVID-19 on liver cancer management (CERO-19). JHEP reports, 3(3), p. 100260. Elsevier 10.1016/j.jhepr.2021.100260
JHEP Reports, Vol 3, Iss 3, Pp 100260-(2021)
JHEP reports : innovation in hepatology, 3(3):100260. Elsevier
Scopus
Muñoz-Martínez, S, Sapena, V, Forner, A, Nault, J C, Sapisochin, G, Rimassa, L, Sangro, B, Bruix, J, Sanduzzi-Zamparelli, M, Hołówko, W, El Kassas, M, Mocan, T, Bouattour, M, Merle, P, Hoogwater, F J H, Alqahtani, S A, Reeves, H L, Pinato, D J, Giorgakis, E, Meyer, T, Villadsen, G E, Wege, H, Salati, M, Mínguez, B, Di Costanzo, G G, Roderburg, C, Tacke, F, Varela, M, Galle, P R, Alvares-da-Silva, M R, Trojan, J, Bridgewater, J, Cabibbo, G, Toso, C, Lachenmayer, A, Casadei-Gardini, A, Toyoda, H, Lüdde, T, Villani, R, Matilla Peña, A M, Guedes Leal, C R, Ronzoni, M, Delgado, M, Perelló, C, Pascual, S, Lledó, J L, Argemi, J, Basu, B, da Fonseca, L, Acevedo, J, Siebenhüner, A R, Braconi, C, Meyers, B M, Granito, A, Sala, M, Rodríguez-Lope, C, Blaise, L, Romero-Gómez, M, Piñero, F, Gomez, D, Mello, V, Pinheiro Alves, R C, França, A, Branco, F, Brandi, G, Pereira, G, Coll, S, Guarino, M, Benítez, C, Anders, M M, Bandi, J C, Vergara, M, Calvo, M, Peck-Radosavljevic, M, García-Juárez, I, Cardinale, V, Lozano, M, Gambato, M, Okolicsanyi, S, Morales-Arraez, D, Elvevi, A, Muñoz, A E, Lué, A, Iavarone, M & Reig, M 2021, ' Assessing the impact of COVID-19 on liver cancer management (CERO-19) ', JHEP Reports, vol. 3, no. 3, 100260 . https://doi.org/10.1016/j.jhepr.2021.100260
JHEP Reports
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
Digital.CSIC. Repositorio Institucional del CSIC
Scientia
[Background & Aims] The coronavirus disease 2019 (COVID-19) pandemic has posed unprecedented challenges to healthcare systems and it may have heavily impacted patients with liver cancer (LC). Herein, we evaluated whether the schedule of LC screening
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc5d91fba7e4b287061ed941a9342414
http://hdl.handle.net/10261/266093
http://hdl.handle.net/10261/266093
Autor:
Bristi Basu, Helen Hatcher, Helena M. Earl, Sue Freeman, Ioannis Gounaris, Penny Moyle, Christine Parkinson, Karen Sayal, James D. Brenton, Mercedes Jimenez-Linan, Mahesh Iddawela, Jean Abraham, Karen Hosking
Publikováno v:
International Journal of Gynecological Cancer
Supplemental digital content is available in the text.
Objective Primary platinum-resistant epithelial ovarian cancer (EOC) is an area of unmet medical need. There is limited evidence from small studies that platinum-based combinations can overc
Objective Primary platinum-resistant epithelial ovarian cancer (EOC) is an area of unmet medical need. There is limited evidence from small studies that platinum-based combinations can overc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e1e8ba10410815470a721963da62e5b
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Frontiers in Oncology
Frontiers in Oncology
Combined hepatocellular-cholangiocarcinoma (cHCC-ICC) is an uncommon and aggressive form of primary liver cancer. Currently, there are no international guidelines for optimal management. For localized tumors, radical resection represents the preferre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4abbea0f3d904df5d3a2017ead55d77
https://www.repository.cam.ac.uk/handle/1810/311289
https://www.repository.cam.ac.uk/handle/1810/311289
Autor:
Carike Coetzee, Hemant M. Kocher, Debashis Sarker, Yathushan Yogeswaran, Christine Hughes, Richard Houghton, Aaron Prendergast, Cheryl Lawrence, Peter Sasieni, Dominic Carlin, Katja N. De Paepe, Sarah Slater, David Propper, Michelle R. Goulart, Kelly Mousa, Maria Pawula, Ahmet Imrali, Fieke E. M. Froeling, Nandita M. deSouza, Bristi Basu, Rhiannon Roberts
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Nature Communications
Nature Communications
Pre-clinical models have shown that targeting pancreatic stellate cells with all-trans-retinoic-acid (ATRA) reprograms pancreatic stroma to suppress pancreatic ductal adenocarcinoma (PDAC) growth. Here, in a phase Ib, dose escalation and expansion, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8f068ac6e5d57fb4bb65f61000a5664
Autor:
Pål Sætrom, Steve Felstead, Robert Nutbrown, Vikash Reebye, David C. Blakey, Robert Habib, Tim Meyer, Rohini Sharma, Mikael H. Sodergren, T.R. Jeff Evans, Kai-Wen Huang, Yuk Ting Ma, Hans E. Huber, Stephanie Dorman, Daniel H. Palmer, Peter Lloyd, Jenni Vasara, Sonia Fairbairn, John J. Rossi, David J. Pinato, Duncan Spalding, Helen Glenny, Ruth Plummer, Pinelopi Andrikakou, Sarah Hunter, Nagy A. Habib, Bristi Basu, Jon Voutila, Joanna Nicholls, Cheng Ean Chee, Vineet Kwatra, David Collin, Debashis Sarker, Madhava Pai, Christopher G. Wood, James Spicer
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 26(15)
Purpose: Transcription factor C/EBP-α (CCAAT/enhancer-binding protein alpha) acts as a master regulator of hepatic and myeloid functions and multiple oncogenic processes. MTL-CEBPA is a first-in-class small activating RNA oligonucleotide drug that u
Publikováno v:
Harrington, J, Carter, L, Basu, B & Cook, N 2018, ' Drug development and clinical trial design in pancreatico-biliary malignancies ', Current Problems in Cancer, vol. 42, no. 1, pp. 73-94 . https://doi.org/10.1016/j.currproblcancer.2018.01.003
Pancreatico-biliary tumours arise from the pancreas, bile duct and Ampulla of Vater. Despite their close anatomical location, they have different aetiology and biology. However, they uniformly share a poor prognosis, with no major improvements observ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcd3840b58b972b6cf18bddd51bca66b
Autor:
J.S. de Bono, Joseph R. Evans, Wolfram Brugger, Susana Carreira, Matthew G Krebs, Elizabeth A. Harrington, Ruth Ruddle, Beth Purchase, Robert H. Jones, Mahesh K. B. Parmar, Alison Turner, Karen E Swales, Udai Banerji, F.M. de Oliveira, Michael Brada, Holly Tovey, Bristi Basu, Emma Hall, Richard H. Wilson, Susana Banerjee, J.C. Dawes, Florence I. Raynaud, Nina Tunariu, James Spicer, N. Steele, Denis Talbot, A.H. Ingles Garces, Raghav Sundar
Publikováno v:
ANNALS OF ONCOLOGY
Basu, B, Krebs, M G, Sundar, R, Wilson, R H, Spicer, J, Jones, R, Brada, M, Talbot, D C, Steele, N, Ingles Garces, A H, Brugger, W, Harrington, E A, Evans, J, Hall, E, Tovey, H, De Oliveira, F M, Carreira, S, Swales, K, Ruddle, R, Raynaud, F I, Purchase, B, Dawes, J C, Parmar, M, Turner, A J, Tunariu, N, Banerjee, S, De Bono, J S & Banerji, U 2018, ' Vistusertib (dual m-TORC1/2 inhibitor) in combination with paclitaxel in patients with high-grade serous ovarian and squamous non-small-cell lung cancer ', Annals of Oncology, vol. 29, no. 9, pp. 1918-1925 . https://doi.org/10.1093/annonc/mdy245
Annals of Oncology
Basu, B, Krebs, M G, Sundar, R, Wilson, R H, Spicer, J, Jones, R, Brada, M, Talbot, D C, Steele, N, Ingles Garces, A H, Brugger, W, Harrington, E A, Evans, J, Hall, E, Tovey, H, De Oliveira, F M, Carreira, S, Swales, K, Ruddle, R, Raynaud, F I, Purchase, B, Dawes, J C, Parmar, M, Turner, A J, Tunariu, N, Banerjee, S, De Bono, J S & Banerji, U 2018, ' Vistusertib (dual m-TORC1/2 inhibitor) in combination with paclitaxel in patients with high-grade serous ovarian and squamous non-small-cell lung cancer ', Annals of Oncology, vol. 29, no. 9, pp. 1918-1925 . https://doi.org/10.1093/annonc/mdy245
Annals of Oncology
Background: \ud We have previously shown that raised p-S6K levels correlate with resistance to chemotherapy in ovarian cancer. We hypothesised that inhibiting p-S6K signalling with the dual m-TORC1/2 inhibitor in patients receiving weekly paclitaxel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::751863d1aac996757bef829196cc6b21