Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Angela M. Crook"'
Pretomanid with bedaquiline and linezolid for drug-resistant TB: a comparison of prospective cohorts
Autor:
Francesca Conradie, G Wills, M. Olugbosi, A Calatroni, Mendel Carl M, Pauline Howell, Daniel Everitt, E Sun, N Ngubane, Aliasgar Esmail, A. del Parigi, Angela M. Crook, Melvin Spigelman, Andreas H. Diacon, Olatunde Olayanju, Keertan Dheda, Suzette Oelofse
Publikováno v:
The International Journal of Tuberculosis and Lung Disease. 25:453-460
BACKGROUND: There are no data comparing the 6–9 month oral three-drug Nix regimen (bedaquiline, pretomanid and linezolid [BPaL]) to conventional regimens containing bedaquiline (B, BDQ) and linezolid (L, LZD).METHODS: Six-month post end-of-treatmen
Autor:
Francesca, Conradie, Andreas H, Diacon, Nosipho, Ngubane, Pauline, Howell, Daniel, Everitt, Angela M, Crook, Carl M, Mendel, Erica, Egizi, Joanna, Moreira, Juliano, Timm, Timothy D, McHugh, Genevieve H, Wills, Anna, Bateson, Robert, Hunt, Christo, Van Niekerk, Mengchun, Li, Morounfolu, Olugbosi, Melvin, Spigelman, Priya, Solanki
Publikováno v:
The New England Journal of Medicine
Patients with highly drug-resistant forms of tuberculosis have limited treatment options and historically have had poor outcomes.In an open-label, single-group study in which follow-up is ongoing at three South African sites, we investigated treatmen
Autor:
Anneke C. Hesseling, E Batist, James A Seddon, S Nkosi, J. Workman, Neil A. Martinson, Susan E. Purchase, Angela M. Crook, H S Schaaf, N Mmile, Louise Choo, Lee Fairlie, C McGowan
Publikováno v:
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease. 25(10)
BACKGROUND: Recruitment to randomised clinical trials can be challenging and slow recruitment has serious consequences. This study aimed to summarise and reflect on the challenges in enrolling young children to a multidrug-resistant TB (MDR-TB) preve
Autor:
G Wills, Andrew J. Nunn, J. Caoili, Mookho Malahleha, Francis Apolinary Mhimbira, Issa Sabi, Muge Cevik, Cheryl Louw, Anna Bateson, Ahmad Izuanuddin Ismail, M. C. Betteridge, Mendel Carl M, Ebrahim Variava, Daniel Everitt, Vincent Balanag, Suzanne Staples, Ronelle Moodliar, Umesh G. Lalloo, L. Lombard, Stephen H. Gillespie, Richard E. Chaisson, Robert D Hunt, Angela M. Crook, Videlis Nduba, Modulakgotla Sebe, Conor D. Tweed, Susan Swindells, Melvin Spigelman, A. Y.L. Ban, Evans Amukoye, C. H. van Niekerk, Andreas H. Diacon, Stella M. Fabiane, A. del Parigi, Rodney Dawson, R. A. P. Selepe, Francesca Conradie, Timothy D. McHugh, William Brumskine
Publikováno v:
The International Journal of Tuberculosis and Lung Disease
STAND was sponsored by TB Alliance with support from the UK Department for International Development, UK Department of Health (London, UK), Bill and Melinda Gates Foundation (Seattle, WA, USA), US Agency for International Development (Washington DC,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23754b0fb1db6916b0fbc5f98df336b9
https://hdl.handle.net/10023/21773
https://hdl.handle.net/10023/21773
Autor:
Angela M. Crook, Claire L Vale, Nurulamin M Noor, Sarah Pett, Hanif Esmail, Matthew R. Sydes, Mahesh K. B. Parmar
Publikováno v:
F1000Research
Global health pandemics, such as coronavirus disease 2019 (COVID-19), require efficient and well-conducted trials to determine effective interventions, such as treatments and vaccinations. Early work focused on rapid sequencing of severe acute respir
Autor:
Louise Choo, Kristen Lebeau, Diana M. Gibb, Angela M. Crook, Robert Mboizi, Lydia Nakiyingi, Willy Ssengooba, Jean de Dieu Iragena, Eric Wobudeya, Anne Marie Demers, David R. Boulware, Fiona V Cresswell, David B. Meya, Moses Joloba, Serestine Mujumbi
Publikováno v:
Journal of Clinical Microbiology
Childhood tuberculosis (TB) presents significant diagnostic challenges associated with paucibacillary disease and requires a more sensitive test. We evaluated the diagnostic accuracy of Xpert MTB/RIF Ultra (Ultra) compared to other microbiological te
Autor:
G Wills, Sara Murthy, Sarah Meredith, Rodney Dawson, Angela M. Crook, Mendel Carl M, Patrick P. J. Phillips, Conor D. Tweed, Stephen H. Gillespie, Andreas H. Diacon, Lerato Mohapi, Cheryl Louw, Melvin Spigelman, Kasha P. Singh, Michael E. P. Murphy, Andrew J. Nunn, Timothy D. McHugh, SR Murray
Publikováno v:
BMC Medicine, Vol 16, Iss 1, Pp 1-10 (2018)
BMC Medicine
BMC medicine, vol 16, iss 1
BMC Medicine
BMC medicine, vol 16, iss 1
This work was supported by the Global Alliance for TB Drug Development with support from the Bill and Melinda Gates Foundation, the European and Developing Countries Clinical Trials Partnership (grant IP.2007.32011.011), the US Agency for Internation
Autor:
Conor D. Tweed, Patrick P. J. Phillips, Kasha P. Singh, Sarah Meredith, Rodney Dawson, Andrew J. Nunn, Andreas H. Diacon, Timothy D. McHugh, Mendel Carl M, Michael E. P. Murphy, Melvin Spigelman, Stephen H. Gillespie, Lerato Mohapi, Angela M. Crook
Publikováno v:
BMC pulmonary medicine, vol 19, iss 1
BMC Pulmonary Medicine, Vol 19, Iss 1, Pp 1-9 (2019)
BMC Pulmonary Medicine
BMC Pulmonary Medicine, Vol 19, Iss 1, Pp 1-9 (2019)
BMC Pulmonary Medicine
Supported by the Global Alliance for TB Drug Development with support from the Bill and Melinda Gates Foundation, the European and Developing Countries Clinical Trials Partnership (grant IP.2007.32011.011), U.S. Agency for International Development,
Autor:
Wolfgang Stöhr, Rodolphe Thiébaut, Yves Levy, Giuseppe Pantaleo, Laura Richert, Stefano Vella, Cecilia L. Moore, Sheena McCormack, Jean Daniel Leliévre, Felipe García, Angela M. Crook
Publikováno v:
The Lancet HIV
The Lancet HIV, 2019, 6 (5), pp.e334-e340. ⟨10.1016/s2352-3018(19)30082-7⟩
Lancet HIV
Lancet HIV, Elsevier, 2019, 6 (5), pp.e334-e340. ⟨10.1016/S2352-3018(19)30082-7⟩
The Lancet HIV, 2019, 6 (5), pp.e334-e340. ⟨10.1016/s2352-3018(19)30082-7⟩
Lancet HIV
Lancet HIV, Elsevier, 2019, 6 (5), pp.e334-e340. ⟨10.1016/S2352-3018(19)30082-7⟩
International audience; The evaluation of immune-based approaches to achieve an antiretroviral therapy free remission of HIV infection requires proven efficacy through antiretroviral therapy interruption placebo-controlled trials. This approach is no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::966401564b57485727bbd8d7e40ee017
https://hal.archives-ouvertes.fr/hal-03160751/file/BPH_Lancet_Moore_2019.pdf
https://hal.archives-ouvertes.fr/hal-03160751/file/BPH_Lancet_Moore_2019.pdf
Autor:
Ebrahim Variava, Suzanne Staples, Mendel Carl M, Andreas H. Diacon, Divan Aristo Burger, Mohammed Rassool, Melvin Spigelman, Angela M. Crook, Daniel Everitt, Christo van Niekerk, Mengchum Li, Rodney Dawson, Klaus Reither, Francesca Conradie, Frederick Haraka, Alphonse Okwera, Nyanda E. Ntinginya, Modulakgotla A. Sebe, Almari Conradie, Connor D. Tweed
Publikováno v:
The Lancet. Respiratory medicine. 7(12)
New anti-tuberculosis regimens that are shorter, simpler, and less toxic than those that are currently available are needed as part of the global effort to address the tuberculosis epidemic. We aimed to investigate the bactericidal activity and safet