Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Ivonne M.C.M. Rietjens"'
Autor:
Isaac Omwenga, Hans G.J. Mol, Jochem Louisse, L W Kanja, Ivonne M.C.M. Rietjens, Shensheng Zhao
Publikováno v:
Archives of Toxicology
Archives of Toxicology, 95(4), 1287-1301
Archives of Toxicology 95 (2021) 4
Archives of Toxicology, 95(4), 1287-1301
Archives of Toxicology 95 (2021) 4
Organophosphate pesticides (OPs) are known to inhibit acetylcholine esterase (AChE), a critical effect used to establish health-based guidance values. This study developed a combined in vitro–in silico approach to predict AChE inhibition by the OP
Publikováno v:
Toxicology in Vitro 79 (2022)
Toxicology in Vitro, 79
Toxicology in Vitro, 79
Potential consequences of combined exposure to the selected food-borne alkenylbenzenes safrole and estragole or their proximate carcinogenic 1′-hydroxy metabolites were evaluated in vitro and in silico. HepG2 cells were exposed to 1′-hydroxyestra
Autor:
Ignacio Miro Estruch, Laura H.J. de Haan, Aziza Hussein Bakheit Adam, Jochem Louisse, Guido J. E. J. Hooiveld, Ivonne M.C.M. Rietjens
Publikováno v:
Cell biology and toxicology, 36, 417-435
Cell Biology and Toxicology
Cell biology and toxicology 36 (2020)
Cell Biology and Toxicology
Cell biology and toxicology 36 (2020)
Diethylstilbestrol (DES) is a synthetic estrogen and proven human teratogen and carcinogen reported to act via the estrogen receptor α (ERα). Since the endogenous ERα ligand 17β-estradiol (E2) does not show these adverse effects to a similar exte
Publikováno v:
Food and Chemical Toxicology 130 (2019)
Food and Chemical Toxicology, 130, 142-153
Food and Chemical Toxicology, 130, 142-153
In this study five types of herbal teas were used to quantify the effect of comminution of the leaves on resulting PA exposure. Results show that PA levels extracted from intact leaves were consistently lower than from comminuted tea leaves. The Marg
Publikováno v:
Food Additives and Contaminants: Part B Surveillance 14 (2021) 1
Food Additives and Contaminants: Part B Surveillance, 14(1), 48-58
Food Additives and Contaminants: Part B Surveillance, 14(1), 48-58
The current study was conducted to assess the levels of organophosphates and carbamates in vegetables in Kenya and to examine potential consumer health risks. A total of 90 samples were analysed by liquid chromatography/high-resolution tandem mass sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e95f2d0c8fb088862c3cb667ad2d42b
https://research.wur.nl/en/publications/organophosphate-and-carbamate-pesticide-residues-and-accompanying
https://research.wur.nl/en/publications/organophosphate-and-carbamate-pesticide-residues-and-accompanying
Autor:
Clara Belzer, Jacques Vervoort, Ben Bruyneel, Ivonne M.C.M. Rietjens, Katja C.W. van Dongen, Meike van der Zande, Karsten Beekmann
Publikováno v:
Toxicology in Vitro, 72
Toxicology in Vitro 72 (2021)
Toxicology in Vitro 72 (2021)
Fructoselysine is formed upon heating during processing of food products, and being a key intermediate in advanced glycation end product formation considered to be potentially hazardous to human health. Human gut microbes can degrade fructoselysine t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0315c9cf4249a36c785abe668b93e02e
https://research.wur.nl/en/publications/an-in-vitro-model-for-microbial-fructoselysine-degradation-shows-
https://research.wur.nl/en/publications/an-in-vitro-model-for-microbial-fructoselysine-degradation-shows-
Autor:
Aziza Hussein Bakheit Adam, Lenny Kamelia, Jochem Louisse, Ivonne M.C.M. Rietjens, Laura H.J. de Haan
Publikováno v:
Toxicology in Vitro 72 (2021)
Toxicology in Vitro, 72
Toxicology in Vitro, 72
The present study investigated the developmental toxicity of diethylstilbestrol (DES) in the zebrafish embryotoxicity test (ZET). This was done to investigate whether the ZET would better capture the developmental toxicity of DES than the embryonic s
Autor:
Laura H.J. de Haan, Miaoying Shi, Nguyen T. Tien, Hans Bouwmeester, Jochem Louisse, Ivonne M.C.M. Rietjens
Publikováno v:
Toxicology in Vitro 67 (2020)
Toxicology in Vitro, 67
Toxicology in Vitro, 67
Cardiotoxicity is an important toxicological endpoint for chemical and drug safety assessment. The present study aims to evaluate two stemcell-based in vitro models for cardiotoxicity screening of chemicals. Eleven model compounds were used to evalua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee809679de1e76b6d673e6ddb7c94b9f
https://research.wur.nl/en/publications/evaluation-of-in-vitro-models-of-stem-cell-derived-cardiomyocytes
https://research.wur.nl/en/publications/evaluation-of-in-vitro-models-of-stem-cell-derived-cardiomyocytes
Autor:
Ivonne M.C.M. Rietjens, Karsten Beekmann, A. Spenkelink, Laura H.J. de Haan, Suparmi Suparmi, Jochem Louisse
Publikováno v:
Molecular Nutrition & Food Research
Molecular Nutrition and Food Research, 64(2)
Molecular Nutrition and Food Research 64 (2020) 2
Molecular Nutrition and Food Research, 64(2)
Molecular Nutrition and Food Research 64 (2020) 2
Scope It is investigated whether at realistic dietary intake bixin and crocetin could induce peroxisome proliferator‐activated receptor γ (PPARγ)‐mediated gene expression in humans using a combined in vitro–in silico approach. Methods and res
Autor:
Jochem Louisse, Rozaini Abdullah, Bert Spenkelink, Sebastiaan Wesseling, Ans Punt, Ivonne M.C.M. Rietjens
Publikováno v:
Journal of Applied Toxicology, 40(12), 1647-1660
Journal of Applied Toxicology 40 (2020) 12
Journal of Applied Toxicology
Journal of Applied Toxicology 40 (2020) 12
Journal of Applied Toxicology
Aristolochic acid I (AAI) is a well‐known genotoxic kidney carcinogen. Metabolic conversion of AAI into the DNA‐reactive aristolactam‐nitrenium ion is involved in the mode of action of tumor formation. This study aims to predict in vivo AAI‐D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdeac367a93739186e038102ba8d7955
https://research.wur.nl/en/publications/defining-in-vivo-dose-response-curves-for-kidney-dna-adduct-forma
https://research.wur.nl/en/publications/defining-in-vivo-dose-response-curves-for-kidney-dna-adduct-forma