Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Breckpot, J"'
Autor:
Barc J; Université de Nantes, CHU Nantes, CNRS, INSERM, l'institut du thorax, Nantes, France. julien.barc@univ-nantes.fr.; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart: ERN GUARD-Heart, . julien.barc@univ-nantes.fr., Tadros R; Department of Clinical and Experimental Cardiology, Heart Centre, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Department of Medicine, Cardiovascular Genetics Center, Montreal Heart Institute and Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada., Glinge C; Department of Clinical and Experimental Cardiology, Heart Centre, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; The Department of Cardiology, The Heart Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark., Chiang DY; Medicine, Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA, USA., Jouni M; Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Simonet F; Université de Nantes, CHU Nantes, CNRS, INSERM, l'institut du thorax, Nantes, France., Jurgens SJ; The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Baudic M; Université de Nantes, CHU Nantes, CNRS, INSERM, l'institut du thorax, Nantes, France., Nicastro M; Department of Clinical and Experimental Cardiology, Heart Centre, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Potet F; Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Offerhaus JA; Department of Clinical and Experimental Cardiology, Heart Centre, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Walsh R; Department of Clinical and Experimental Cardiology, Heart Centre, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Choi SH; The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Verkerk AO; Department of Clinical and Experimental Cardiology, Heart Centre, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Department of Medical Biology, University of Amsterdam, Amsterdam University Medical Centers, Amsterdam, The Netherlands., Mizusawa Y; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart: ERN GUARD-Heart.; Department of Clinical and Experimental Cardiology, Heart Centre, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Anys S; Université de Nantes, CHU Nantes, CNRS, INSERM, l'institut du thorax, Nantes, France., Minois D; Université de Nantes, CHU Nantes, CNRS, INSERM, l'institut du thorax, Nantes, France., Arnaud M; Université de Nantes, CHU Nantes, CNRS, INSERM, l'institut du thorax, Nantes, France., Duchateau J; IHU Liryc, Electrophysiology and Heart Modeling Institute, fondation Bordeaux Université, Pessac-Bordeaux, France.; Université Bordeaux, Centre de recherche Cardio-Thoracique de Bordeaux, Bordeaux, France.; INSERM, Centre de recherche Cardio-Thoracique de Bordeaux, Bordeaux, France.; Electrophysiology and Ablation Unit, Bordeaux University Hospital (CHU), Pessac, France., Wijeyeratne YD; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart: ERN GUARD-Heart.; Molecular and Clinical Sciences Research Institute, St. George's, University of London, London, UK.; Cardiology Clinical Academic Group, St. George's University Hospitals' NHS Foundation Trust, London, UK., Muir A; Cardiology, Belfast Health and Social Care Trust and Queen's University Belfast, Belfast, UK., Papadakis M; Molecular and Clinical Sciences Research Institute, St. George's, University of London, London, UK.; Cardiology Clinical Academic Group, St. George's University Hospitals' NHS Foundation Trust, London, UK., Castelletti S; Center for Cardiac Arrhythmias of Genetic Origin, Istituto Auxologico Italiano IRCCS, Milan, Italy., Torchio M; Laboratory of Cardiovascular Genetics, Istituto Auxologico Italiano IRCCS, Cusano Milanino, Italy., Ortuño CG; Cardiogenetic, Unidad de Cardiopatías Familiares, Instituto Murciano de Investigación Biosanitaria, Universidad de Murcia, Murcia, Spain., Lacunza J; Cardiology, Unidad de Cardiopatías Familiares, Hospital Universitario Virgen de la Arrixaca, Universidad de Murcia, Murcia, Spain., Giachino DF; Clinical and Biological Sciences, Medical Genetics, University of Torino, Orbassano, Italy.; Medical Genetics, San Luigi Gonzaga University Hospital, Orbassano, Italy., Cerrato N; Medical Sciences, Cardiology, University of Torino, Torino, Italy., Martins RP; Cardiologie et Maladies vasculaires, Université Rennes1 - CHU Rennes, Rennes, France., Campuzano O; Cardiovascular Genetics Center, University of Girona-IDIBGI, Girona, Spain.; Medical Science Department, University of Girona, Girona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Madrid, Spain.; Biochemistry and Molecular Genetics Department, Hospital Clinic, University of Barcelona-IDIBAPS, Barcelona, Spain., Van Dooren S; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart: ERN GUARD-Heart.; Centre for Medical Genetics, research group Reproduction and Genetics, research cluster Reproduction, Genetics and Regenerative Medicine, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Brussels, Belgium., Thollet A; Université de Nantes, CHU Nantes, CNRS, INSERM, l'institut du thorax, Nantes, France., Kyndt F; Université de Nantes, CHU Nantes, CNRS, INSERM, l'institut du thorax, Nantes, France., Mazzanti A; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart: ERN GUARD-Heart.; Molecular Cardiology, ICS Maugeri, IRCCS and Department of Molecular Medicine, University of Pavia, Pavia, Italy., Clémenty N; Department of Cardiology, CHU Tours, Tours, France., Bisson A; Department of Cardiology, CHU Tours, Tours, France., Corveleyn A; Department of Human Genetics, Catholic University Leuven, Leuven, Belgium., Stallmeyer B; University Hospital Münster, Institute for Genetics of Heart Diseases (IfGH), Münster, Germany., Dittmann S; University Hospital Münster, Institute for Genetics of Heart Diseases (IfGH), Münster, Germany., Saenen J; Cardiology, Electrophysiology - Cardiogenetics, University of Antwerp/Antwerp University Hospital, Edegem, Belgium., Noël A; Department of Cardiology, University Hospital of Brest, Brest, France., Honarbakhsh S; Cardiology, Medicine, Barts Heart Centre, London, UK., Rudic B; Department 1st of Medicine, Cardiology, University Medical Center Mannheim, Mannheim, Germany.; German Center for Cardiovascular Research (DZHK), Mannheim, Germany., Marzak H; Department of Cardiology, University Hospital of Strasbourg, Strasbourg, France., Rowe MK; Medicine, Cardiology, Western University, London, Ontario, Canada., Federspiel C; Department of Cardiovascular Medicine, Vendée Hospital, Service de Cardiologie, La Roche sur Yon, France., Le Page S; Service de cardiologie, CHU Angers, Angers, France., Placide L; Department of Cardiology, CHU Montpellier, Montpellier, France., Milhem A; Department of Cardiology, CH La Rochelle, La Rochelle, France., Barajas-Martinez H; Lankenau Institute for Medical Research, Wynnewood, PA, USA., Beckmann BM; Department of Medicine I, University Hospital, LMU Munich, Munich, Germany.; University Hospital of the Johann Wolfgang Goethe University Frankfurt, Institute of Legal Medicine, Frankfurt, Germany., Krapels IP; Department of Clinical Genetics, Maastricht University Medical Center, Maastricht, The Netherlands., Steinfurt J; Department of Cardiology and Angiology I, Heart Center, University Freiburg, Freiburg, Germany., Winkel BG; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart: ERN GUARD-Heart.; The Department of Cardiology, The Heart Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark., Jabbari R; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart: ERN GUARD-Heart.; The Department of Cardiology, The Heart Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark., Shoemaker MB; Medicine, Cardiology, Vanderbilt University Medical Center, Nashville, TN, USA., Boukens BJ; Department of Medical Biology, University of Amsterdam, Amsterdam University Medical Centers, Amsterdam, The Netherlands., Škorić-Milosavljević D; Department of Clinical and Experimental Cardiology, Heart Centre, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Bikker H; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart: ERN GUARD-Heart.; Genome Diagnostics Laboratory, Clinical Genetics, Amsterdam UMC, Amsterdam, The Netherlands., Manevy F; Department of Clinical and Experimental Cardiology, Heart Centre, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Lichtner P; Institute of Human Genetics, Helmholtz Zentrum München, Neuherberg, Germany., Ribasés M; Psychiatric Genetics Unit, Institute Vall d'Hebron Research (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain., Meitinger T; Institute of Human Genetics, Helmholtz Zentrum München, Neuherberg, Germany., Müller-Nurasyid M; Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.; IBE, LMU Munich, Munich, Germany.; Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI), University Medical Center, Johannes Gutenberg University, Mainz, Germany.; Department of Internal Medicine I (Cardiology), Hospital of the Ludwig-Maximilians-University (LMU) Munich, Munich, Germany., Veldink JH; Department of Neurology, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., van den Berg LH; Department of Neurology, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Van Damme P; Neurology Department University Hospital Leuven, Neuroscience Department KU Leuven, Center for Brain & Disease Research VIB, Leuven, Belgium., Cusi D; Scientific Unit, Bio4Dreams - Business Nursery for Life Sciences, Milan, Italy., Lanzani C; Nephrology, Genomics of Renal Diseases and Hypertension Unit, Università Vita Salute San Raffaele, Milan, Italy., Rigade S; Université de Nantes, CHU Nantes, CNRS, INSERM, l'institut du thorax, Nantes, France., Charpentier E; Université de Nantes, CHU Nantes, CNRS, INSERM, l'institut du thorax, Nantes, France.; Université de Nantes, CHU Nantes, Inserm, CNRS, SFR Santé, Inserm UMS 016, CNRS UMS 3556, Nantes, France., Baron E; Université de Nantes, CHU Nantes, CNRS, INSERM, l'institut du thorax, Nantes, France., Bonnaud S; Université de Nantes, CHU Nantes, CNRS, INSERM, l'institut du thorax, Nantes, France.; Université de Nantes, CHU Nantes, Inserm, CNRS, SFR Santé, Inserm UMS 016, CNRS UMS 3556, Nantes, France., Lecointe S; Université de Nantes, CHU Nantes, CNRS, INSERM, l'institut du thorax, Nantes, France., Donnart A; Université de Nantes, CHU Nantes, CNRS, INSERM, l'institut du thorax, Nantes, France.; Université de Nantes, CHU Nantes, Inserm, CNRS, SFR Santé, Inserm UMS 016, CNRS UMS 3556, Nantes, France., Le Marec H; Université de Nantes, CHU Nantes, CNRS, INSERM, l'institut du thorax, Nantes, France., Chatel S; Université de Nantes, CHU Nantes, CNRS, INSERM, l'institut du thorax, Nantes, France., Karakachoff M; Université de Nantes, CHU Nantes, CNRS, INSERM, l'institut du thorax, Nantes, France., Bézieau S; Université de Nantes, CHU Nantes, CNRS, INSERM, l'institut du thorax, Nantes, France., London B; Department of Internal Medicine, Division of Cardiovascular Medicine, Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA, USA., Tfelt-Hansen J; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart: ERN GUARD-Heart.; The Department of Cardiology, The Heart Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.; Department of Forensic Medicine, University of Copenhagen, Copenhagen, Denmark., Roden D; Medicine, Clinical Pharmacology, Vanderbilt University Medical Center, Nashville, TN, USA.; Medicine, Pharmacology, Vanderbilt University Medical Center, Nashville, TN, USA.; Medicine, Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA., Odening KE; Department of Cardiology and Angiology I, Heart Center, University Freiburg, Freiburg, Germany.; Department of Cardiology, Translational Cardiology, University Hospital Bern, Bern, Switzerland., Cerrone M; Medicine, Leon H. Charney Division of Cardiology, Heart Rhythm Center and Cardiovascular Genetics Program, New York University School of Medicine, New York, NY, USA., Chinitz LA; Medicine, Leon H. Charney Division of Cardiology, Heart Rhythm Center and Cardiovascular Genetics Program, New York University School of Medicine, New York, NY, USA., Volders PG; Department of Cardiology, CARIM, Maastricht University Medical Center, Maastricht, The Netherlands., van de Berg MP; Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Laurent G; Cardiology Department, ImVia lab team IFTIM, University Hospital Dijon, Dijon, France., Faivre L; Centre de Génétique, FHU TRANSLAD, Dijon, France., Antzelevitch C; Lankenau Institute for Medical Research, Wynnewood, PA, USA., Kääb S; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart: ERN GUARD-Heart.; Department of Medicine I, University Hospital, LMU Munich, Munich, Germany.; German Center for Cardiovascular Research (DZHK), Partnersite Munich, Munich, Germany., Arnaout AA; Department of Cardiology, CH La Rochelle, La Rochelle, France., Dupuis JM; Service de cardiologie, CHU Angers, Angers, France., Pasquie JL; Department of Cardiology, CNRS UMR9214 - Inserm U1046 - PHYMEDEXP, Université de Montpellier et CHU Montpellier, Montpellier, France., Billon O; Department of Cardiovascular Medicine, Vendée Hospital, Service de Cardiologie, La Roche sur Yon, France., Roberts JD; Medicine, Cardiology, Western University, London, Ontario, Canada., Jesel L; Department of Cardiology, University Hospital of Strasbourg, Strasbourg, France.; INSERM 1260 - Regenerative Nanomedecine, University of Strasbourg, Strasbourg, France., Borggrefe M; Department 1st of Medicine, Cardiology, University Medical Center Mannheim, Mannheim, Germany.; German Center for Cardiovascular Research (DZHK), Mannheim, Germany., Lambiase PD; Cardiology, Medicine, Barts Heart Centre, London, UK.; Institute of Cardiovasculr Science, UCL, Population Health, UCL, London, UK., Mansourati J; Department of Cardiology, University Hospital of Brest, Brest, France., Loeys B; Center for Medical Genetics, Cardiogenetics, University of Antwerp/Antwerp University Hospital, Edegem, Belgium., Leenhardt A; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart: ERN GUARD-Heart.; Department of Cardiology, Hopital Bichat, Paris, France., Guicheney P; Sorbonne Université, Paris, France.; UMR_S1166, Faculté de médecine, Sorbonne Université, INSERM, Paris, France., Maury P; Service de cardiologie, Hôpital Rangueil, CHU de Toulouse, Toulouse, France., Schulze-Bahr E; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart: ERN GUARD-Heart.; University Hospital Münster, Institute for Genetics of Heart Diseases (IfGH), Münster, Germany., Robyns T; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart: ERN GUARD-Heart.; Cardiovascular Diseases, University Hospitals Leuven, Leuven, Belgium.; Cardiovascular Sciences, University of Leuven, Leuven, Belgium., Breckpot J; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart: ERN GUARD-Heart.; Department of Human Genetics, Catholic University Leuven, Leuven, Belgium., Babuty D; Department of Cardiology, CHU Tours, Tours, France., Priori SG; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart: ERN GUARD-Heart.; Molecular Cardiology, ICS Maugeri, IRCCS and Department of Molecular Medicine, University of Pavia, Pavia, Italy., Napolitano C; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart: ERN GUARD-Heart.; Molecular Cardiology, ICS Maugeri, IRCCS and Department of Molecular Medicine, University of Pavia, Pavia, Italy., de Asmundis C; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart: ERN GUARD-Heart.; Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Madrid, Spain.; Heart Rhythm Management Center, Postgraduate Program in Cardiac Electrophysiology and Pacing Universitair Ziekenhuis, Brussel-Vrije Universiteit Brussel, ERN Heart Guard Center, Brussels, Belgium.; IDIBAPS, Institut d'Investigació August Pi i Sunyer (IDIBAPS), Barcelona, Spain., Brugada P; Heart Rhythm Management Center, UZ Brussel-VUB, Brussels, Belgium., Brugada R; Hospital Trueta, CiberCV, University of Girona, IDIBGI, Girona, Spain, Barcelona, Spain., Arbelo E; Arrhythmia Section, Cardiology Department, Hospital Clínic, Universitat de Barcelona, Barcelona, Spain., Brugada J; Cardiovascular Institute, Hospital Clinic, University of Barcelona, Barcelona, Spain., Mabo P; Cardiologie et Maladies vasculaires, Université Rennes1 - CHU Rennes, Rennes, France., Behar N; Cardiologie et Maladies vasculaires, Université Rennes1 - CHU Rennes, Rennes, France., Giustetto C; Medical Sciences, Cardiology, University of Torino, Torino, Italy., Molina MS; Cardiogenetic, Unidad de Cardiopatías Familiares, Instituto Murciano de Investigación Biosanitaria, Universidad de Murcia, Murcia, Spain., Gimeno JR; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart: ERN GUARD-Heart.; Cardiology, Unidad de Cardiopatías Familiares, Hospital Universitario Virgen de la Arrixaca, Universidad de Murcia, Murcia, Spain., Hasdemir C; Department of Cardiology, Ege University School of Medicine, Bornova, Turkey., Schwartz PJ; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart: ERN GUARD-Heart.; Center for Cardiac Arrhythmias of Genetic Origin, Istituto Auxologico Italiano IRCCS, Milan, Italy.; Laboratory of Cardiovascular Genetics, Istituto Auxologico Italiano IRCCS, Cusano Milanino, Italy., Crotti L; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart: ERN GUARD-Heart.; Center for Cardiac Arrhythmias of Genetic Origin, Istituto Auxologico Italiano IRCCS, Milan, Italy.; Laboratory of Cardiovascular Genetics, Istituto Auxologico Italiano IRCCS, Cusano Milanino, Italy.; Department of Cardiovascular, Neural and Metabolic Sciences, San Luca Hospital, Istituto Auxologico Italiano IRCCS, Milan, Italy.; Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy., McKeown PP; Cardiology, Belfast Health and Social Care Trust and Queen's University Belfast, Belfast, UK., Sharma S; Molecular and Clinical Sciences Research Institute, St. George's, University of London, London, UK.; Cardiology Clinical Academic Group, St. George's University Hospitals' NHS Foundation Trust, London, UK., Behr ER; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart: ERN GUARD-Heart.; Molecular and Clinical Sciences Research Institute, St. George's, University of London, London, UK.; Cardiology Clinical Academic Group, St. George's University Hospitals' NHS Foundation Trust, London, UK., Haissaguerre M; IHU Liryc, Electrophysiology and Heart Modeling Institute, fondation Bordeaux Université, Pessac-Bordeaux, France.; Université Bordeaux, Centre de recherche Cardio-Thoracique de Bordeaux, Bordeaux, France.; INSERM, Centre de recherche Cardio-Thoracique de Bordeaux, Bordeaux, France.; Electrophysiology and Ablation Unit, Bordeaux University Hospital (CHU), Pessac, France., Sacher F; IHU Liryc, Electrophysiology and Heart Modeling Institute, fondation Bordeaux Université, Pessac-Bordeaux, France.; Université Bordeaux, Centre de recherche Cardio-Thoracique de Bordeaux, Bordeaux, France.; INSERM, Centre de recherche Cardio-Thoracique de Bordeaux, Bordeaux, France.; Electrophysiology and Ablation Unit, Bordeaux University Hospital (CHU), Pessac, France., Rooryck C; CHU Bordeaux, Service de Génétique Médicale, Bordeaux, France.; Université de Bordeaux, Maladies Rares: Génétique et Métabolisme (MRGM), INSERM U1211, Bordeaux, France., Tan HL; Department of Clinical and Experimental Cardiology, Heart Centre, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Netherlands Heart Institute, Utrecht, The Netherlands., Remme CA; Department of Clinical and Experimental Cardiology, Heart Centre, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Postema PG; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart: ERN GUARD-Heart.; Department of Clinical and Experimental Cardiology, Heart Centre, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Delmar M; Medicine, Cardiology, New York University School of Medicine, New York, NY, USA., Ellinor PT; Cardiac Arrhythmia Service and Cardiovascular Research Center, Massachusetts General Hospital and Cardiovascular Disease Initiative, The Broad Institute of MIT and Harvard, Boston, MA, USA., Lubitz SA; Cardiac Arrhythmia Service and Cardiovascular Research Center, Massachusetts General Hospital and Cardiovascular Disease Initiative, The Broad Institute of MIT and Harvard, Boston, MA, USA., Gourraud JB; Université de Nantes, CHU Nantes, CNRS, INSERM, l'institut du thorax, Nantes, France.; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart: ERN GUARD-Heart., Tanck MW; Clinical Epidemiology, Biostatistics and Bioinformatics, Clinical Methods and Public Health, Amsterdam Public Health, Amsterdam, The Netherlands., George AL Jr; Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Center for Pharmacogenomics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., MacRae CA; Medicine, Cardiovascular Medicine, Genetics and Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Burridge PW; Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Center for Pharmacogenomics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Dina C; Université de Nantes, CHU Nantes, CNRS, INSERM, l'institut du thorax, Nantes, France., Probst V; Université de Nantes, CHU Nantes, CNRS, INSERM, l'institut du thorax, Nantes, France.; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart: ERN GUARD-Heart., Wilde AA; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart: ERN GUARD-Heart.; Department of Clinical and Experimental Cardiology, Heart Centre, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Schott JJ; Université de Nantes, CHU Nantes, CNRS, INSERM, l'institut du thorax, Nantes, France.; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart: ERN GUARD-Heart., Redon R; Université de Nantes, CHU Nantes, CNRS, INSERM, l'institut du thorax, Nantes, France.; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart: ERN GUARD-Heart., Bezzina CR; European Reference Network for Rare and Low Prevalence Complex Diseases of the Heart: ERN GUARD-Heart, . c.r.bezzina@amsterdamumc.nl.; Department of Clinical and Experimental Cardiology, Heart Centre, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands. c.r.bezzina@amsterdamumc.nl.
Publikováno v:
Nature genetics [Nat Genet] 2022 Mar; Vol. 54 (3), pp. 232-239. Date of Electronic Publication: 2022 Feb 24.
Autor:
Walsh R; Department of Clinical and Experimental Cardiology, Heart Centre, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands. r.t.walsh@amsterdamumc.nl.; Member of the European Reference Network for rare, low prevalence and/or complex diseases of the heart: ERN GUARD-Heart, Amsterdam, Netherlands. r.t.walsh@amsterdamumc.nl., Lahrouchi N; Department of Clinical and Experimental Cardiology, Heart Centre, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.; Member of the European Reference Network for rare, low prevalence and/or complex diseases of the heart: ERN GUARD-Heart, Amsterdam, Netherlands., Tadros R; Department of Medicine, Cardiovascular Genetics Center, Montreal Heart Institute and Faculty of Medicine, Université de Montréal, Montreal, QC, Canada., Kyndt F; Member of the European Reference Network for rare, low prevalence and/or complex diseases of the heart: ERN GUARD-Heart, Amsterdam, Netherlands.; Université de Nantes, CHU Nantes, CNRS, INSERM, l'institut du thorax, Nantes, France., Glinge C; Member of the European Reference Network for rare, low prevalence and/or complex diseases of the heart: ERN GUARD-Heart, Amsterdam, Netherlands.; Department of Cardiology, The Heart Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark., Postema PG; Department of Clinical and Experimental Cardiology, Heart Centre, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.; Member of the European Reference Network for rare, low prevalence and/or complex diseases of the heart: ERN GUARD-Heart, Amsterdam, Netherlands., Amin AS; Department of Clinical and Experimental Cardiology, Heart Centre, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.; Member of the European Reference Network for rare, low prevalence and/or complex diseases of the heart: ERN GUARD-Heart, Amsterdam, Netherlands., Nannenberg EA; Member of the European Reference Network for rare, low prevalence and/or complex diseases of the heart: ERN GUARD-Heart, Amsterdam, Netherlands.; Department of Clinical Genetics, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands., Ware JS; National Heart and Lung Institute, Imperial College London, London, United Kingdom.; Cardiovascular Research Centre, Royal Brompton and Harefield NHS Foundation Trust, London, United Kingdom.; MRC London Institute of Medical Sciences, Imperial College London, London, United Kingdom., Whiffin N; National Heart and Lung Institute, Imperial College London, London, United Kingdom.; Cardiovascular Research Centre, Royal Brompton and Harefield NHS Foundation Trust, London, United Kingdom.; MRC London Institute of Medical Sciences, Imperial College London, London, United Kingdom., Mazzarotto F; National Heart and Lung Institute, Imperial College London, London, United Kingdom.; Cardiovascular Research Centre, Royal Brompton and Harefield NHS Foundation Trust, London, United Kingdom.; Cardiomyopathy Unit, Careggi University Hospital, Florence, Italy.; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy., Škorić-Milosavljević D; Department of Clinical and Experimental Cardiology, Heart Centre, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.; Member of the European Reference Network for rare, low prevalence and/or complex diseases of the heart: ERN GUARD-Heart, Amsterdam, Netherlands., Krijger C; Department of Clinical and Experimental Cardiology, Heart Centre, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.; Member of the European Reference Network for rare, low prevalence and/or complex diseases of the heart: ERN GUARD-Heart, Amsterdam, Netherlands., Arbelo E; Arrhythmia Section, Cardiology Department, Hospital Clínic, Universitat de Barcelona, Barcelona, Spain.; IDIBAPS, Institut d'Investigació August Pi i Sunyer (IDIBAPS), Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Madrid, Spain., Babuty D; CHU Tours, Service de Cardiologie, Tours, France., Barajas-Martinez H; Lankenau Institute for Medical Research, Wynnewood, PA, USA., Beckmann BM; Department of Internal Medicine I, LMU Klinikum, Klinikum der Ludwig Maximilians Universität München, München, Germany., Bézieau S; Member of the European Reference Network for rare, low prevalence and/or complex diseases of the heart: ERN GUARD-Heart, Amsterdam, Netherlands.; Université de Nantes, CHU Nantes, CNRS, INSERM, l'institut du thorax, Nantes, France., Bos JM; Department of Cardiovascular Medicine, Division of Heart Rhythm Services, Mayo Clinic, Rochester, MN, USA., Breckpot J; Member of the European Reference Network for rare, low prevalence and/or complex diseases of the heart: ERN GUARD-Heart, Amsterdam, Netherlands.; Department of Human Genetics, University Hospitals Leuven, Leuven, Belgium., Campuzano O; Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Madrid, Spain.; Cardiovascular Genetics Center, University of Girona-IDIBGI, Girona, Spain.; Medical Science Department, School of Medicine, University of Girona, Girona, Spain.; Biochemistry and Molecular Genetics Department, Hospital Clinic, University of Barcelona-IDIBAPS, Barcelona, Spain., Castelletti S; Istituto Auxologico Italiano, IRCCS-Center for Cardiac Arrhythmias of Genetic Origin, Milan, Italy., Celen C; Department of Cardiology, Ege University School of Medicine, Izmir, Turkey., Clauss S; Department of Internal Medicine I, LMU Klinikum, Klinikum der Ludwig Maximilians Universität München, München, Germany.; German Centre for Cardiovascular Research (DZHK), Partner Site Munich, Munich Heart Alliance (MHA), Munich, Germany.; Walter Brendel Centre of Experimental Medicine, Ludwig-Maximilians University Munich (LMU), Munich, Germany., Corveleyn A; Member of the European Reference Network for rare, low prevalence and/or complex diseases of the heart: ERN GUARD-Heart, Amsterdam, Netherlands.; Center for Human Genetics, University Hospitals Leuven, Leuven, Belgium., Crotti L; Istituto Auxologico Italiano, IRCCS-Center for Cardiac Arrhythmias of Genetic Origin, Milan, Italy.; Istituto Auxologico Italiano, IRCCS, Department of Cardiovascular, Neural and Metabolic Sciences, San Luca Hospital, Milan, Italy.; Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.; Istituto Auxologico Italiano, IRCCS-Laboratory of Cardiovascular Genetics, Cusano Milanino, MI, Italy., Dagradi F; Istituto Auxologico Italiano, IRCCS-Center for Cardiac Arrhythmias of Genetic Origin, Milan, Italy., de Asmundis C; Heart Rhythm Management Center, Postgraduate program in Cardiac Electrophysiology and Pacing Universitair Ziekenhuis, Brussel-Vrije Universiteit Brussel, ERN Heart Guard Center, Brussels, Belgium., Denjoy I; Member of the European Reference Network for rare, low prevalence and/or complex diseases of the heart: ERN GUARD-Heart, Amsterdam, Netherlands.; CNMR Maladies Cardiaques Héréditaires Rares, Hôpital Bichat, Université de Paris, Paris, France.; AP-HP, Service de Cardiologie, Hôpital Bichat, Paris, France., Dittmann S; Member of the European Reference Network for rare, low prevalence and/or complex diseases of the heart: ERN GUARD-Heart, Amsterdam, Netherlands.; Institute for Genetics of Heart Diseases, University Hospital Münster, Münster, Germany., Ellinor PT; Cardiac Arrhythmia Service and Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.; Cardiovascular Disease Initiative, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA, USA., Ortuño CG; Member of the European Reference Network for rare, low prevalence and/or complex diseases of the heart: ERN GUARD-Heart, Amsterdam, Netherlands.; Cardiogenetic Laboratory, Inherited Cardiac Disease Unit, University Hospital Virgen de la Arrixaca-IMIB, Murcia, Spain., Giustetto C; Division of Cardiology, University of Torino, Department of Medical Sciences, 'Città della Salute e della Scienza' Hospital, Torino, Italy., Gourraud JB; Member of the European Reference Network for rare, low prevalence and/or complex diseases of the heart: ERN GUARD-Heart, Amsterdam, Netherlands.; Université de Nantes, CHU Nantes, CNRS, INSERM, l'institut du thorax, Nantes, France., Hazeki D; Department of Pediatrics, Kagoshima City Hospital, Kagoshima, Japan., Horie M; Center for Epidemiologic Research in Asia, Shiga University of Medical Science, Seta-Tsukinowa-cho, Otsu, Japan., Ishikawa T; Omics Research Center, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan., Itoh H; Division of Patient Safety, Hiroshima University Hospital, Minami-ku, Hiroshima, Japan., Kaneko Y; Department of Cardiovascular Medicine, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan., Kanters JK; Laboratory of Experimental Cardiology, Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark., Kimoto H; Department of Molecular Physiology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan., Kotta MC; Istituto Auxologico Italiano, IRCCS-Center for Cardiac Arrhythmias of Genetic Origin, Milan, Italy.; Istituto Auxologico Italiano, IRCCS-Laboratory of Cardiovascular Genetics, Cusano Milanino, MI, Italy., Krapels IPC; Department of Clinical Genetics, Maastricht University Medical Center+, Maastricht, Netherlands., Kurabayashi M; Department of Cardiovascular Medicine, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan., Lazarte J; Department of Medicine and Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada., Leenhardt A; Member of the European Reference Network for rare, low prevalence and/or complex diseases of the heart: ERN GUARD-Heart, Amsterdam, Netherlands.; CNMR Maladies Cardiaques Héréditaires Rares, Hôpital Bichat, Université de Paris, Paris, France.; AP-HP, Service de Cardiologie, Hôpital Bichat, Paris, France., Loeys BL; Center of Medical Genetics, Faculty of Medicine and Health Sciences, University of Antwerp and Antwerp University Hospital, Antwerp, Belgium., Lundin C; Department of Clinical Genetics and Pathology, Lund University, Lund, Sweden., Makiyama T; Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan., Mansourati J; CHU Brest, Service de Cardiologie, Brest, France., Martins RP; Univ Rennes, CHU Rennes, INSERM, Rennes, France., Mazzanti A; Member of the European Reference Network for rare, low prevalence and/or complex diseases of the heart: ERN GUARD-Heart, Amsterdam, Netherlands.; Molecular Cardiology, ICS Maugeri, IRCCS and Department of Molecular Medicine, University of Pavia, Pavia, Italy., Mörner S; Member of the European Reference Network for rare, low prevalence and/or complex diseases of the heart: ERN GUARD-Heart, Amsterdam, Netherlands.; Centre for Cardiovascular Genetics, Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden., Napolitano C; Member of the European Reference Network for rare, low prevalence and/or complex diseases of the heart: ERN GUARD-Heart, Amsterdam, Netherlands.; Molecular Cardiology, ICS Maugeri, IRCCS and Department of Molecular Medicine, University of Pavia, Pavia, Italy., Ohkubo K; Department of Cardiovascular Medicine, Nihon University, Tokyo, Japan., Papadakis M; Member of the European Reference Network for rare, low prevalence and/or complex diseases of the heart: ERN GUARD-Heart, Amsterdam, Netherlands.; Molecular and Clinical Sciences Research Institute, St. George's, University of London, London, United Kingdom.; Cardiology Clinical Academic Group, St. George's University Hospitals' NHS Foundation Trust, London, United Kingdom., Rudic B; Department of Medicine, University Medical Center Mannheim, Mannheim, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Heidelberg/Mannheim, Mannheim, Germany., Molina MS; Member of the European Reference Network for rare, low prevalence and/or complex diseases of the heart: ERN GUARD-Heart, Amsterdam, Netherlands.; Cardiogenetic Laboratory, Inherited Cardiac Disease Unit, University Hospital Virgen de la Arrixaca-IMIB, Murcia, Spain., Sacher F; Hôpital Cardiologique du Haut-Lévêque, LIRYC Institute, Université Bordeaux, Bordeaux, France., Sahin H; Department of Cardiology, Ege University School of Medicine, Izmir, Turkey., Sarquella-Brugada G; Member of the European Reference Network for rare, low prevalence and/or complex diseases of the heart: ERN GUARD-Heart, Amsterdam, Netherlands.; Medical Science Department, School of Medicine, University of Girona, Girona, Spain.; Arrhythmias Unit, Hospital Sant Joan de Déu, University of Barcelona, Barcelona, Spain., Sebastiano R; Medical Genetics, San Luigi Univesity Hospital, Orbassano, TO, Italy., Sharma S; Member of the European Reference Network for rare, low prevalence and/or complex diseases of the heart: ERN GUARD-Heart, Amsterdam, Netherlands.; Molecular and Clinical Sciences Research Institute, St. George's, University of London, London, United Kingdom.; Cardiology Clinical Academic Group, St. George's University Hospitals' NHS Foundation Trust, London, United Kingdom., Sheppard MN; Member of the European Reference Network for rare, low prevalence and/or complex diseases of the heart: ERN GUARD-Heart, Amsterdam, Netherlands.; Molecular and Clinical Sciences Research Institute, St. George's, University of London, London, United Kingdom.; Cardiology Clinical Academic Group, St. George's University Hospitals' NHS Foundation Trust, London, United Kingdom., Shimamoto K; Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Japan., Shoemaker MB; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Stallmeyer B; Member of the European Reference Network for rare, low prevalence and/or complex diseases of the heart: ERN GUARD-Heart, Amsterdam, Netherlands.; Institute for Genetics of Heart Diseases, University Hospital Münster, Münster, Germany., Steinfurt J; Department of Cardiology and Angiology I, Heart Center University of Freiburg, Medical Faculty, Freiburg, Germany., Tanaka Y; Department of Pediatrics, National Hospital Organization Kagoshima Medical Center, Kagoshima, Japan., Tester DJ; Department of Cardiovascular Medicine, Division of Heart Rhythm Services, Mayo Clinic, Rochester, MN, USA., Usuda K; Department of Cardiovascular Medicine, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Japan., van der Zwaag PA; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, Netherlands., Van Dooren S; Member of the European Reference Network for rare, low prevalence and/or complex diseases of the heart: ERN GUARD-Heart, Amsterdam, Netherlands.; Centre for Medical Genetics, research group Reproduction and Genetics, research cluster Reproduction, Genetics and Regenerative Medicine, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Brussels, Belgium., Van Laer L; Center of Medical Genetics, Faculty of Medicine and Health Sciences, University of Antwerp and Antwerp University Hospital, Antwerp, Belgium., Winbo A; Department of Physiology, University of Auckland, Auckland, New Zealand., Winkel BG; Member of the European Reference Network for rare, low prevalence and/or complex diseases of the heart: ERN GUARD-Heart, Amsterdam, Netherlands.; Department of Cardiology, The Heart Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark., Yamagata K; Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Japan., Zumhagen S; Member of the European Reference Network for rare, low prevalence and/or complex diseases of the heart: ERN GUARD-Heart, Amsterdam, Netherlands.; Institute for Genetics of Heart Diseases, University Hospital Münster, Münster, Germany., Volders PGA; Department of Cardiology, CARIM, Maastricht University Medical Center+, Maastricht, Netherlands., Lubitz SA; Cardiac Arrhythmia Service and Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.; Cardiovascular Disease Initiative, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA, USA., Antzelevitch C; Lankenau Institute for Medical Research, Wynnewood, PA, USA., Platonov PG; Department of Cardiology, Clinical Sciences, Lund University, Lund, Sweden., Odening KE; Department of Cardiology and Angiology I, Heart Center University of Freiburg, Medical Faculty, Freiburg, Germany.; Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Roden DM; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Pharmacology, Vanderbilt University Medical Center, Nashville, TN, USA., Roberts JD; Section of Cardiac Electrophysiology, Division of Cardiology, Department of Medicine, Western University, London, ON, Canada., Skinner JR; Cardiac Inherited Disease Group, Starship Childrens Hospital, Auckland, New Zealand., Tfelt-Hansen J; Member of the European Reference Network for rare, low prevalence and/or complex diseases of the heart: ERN GUARD-Heart, Amsterdam, Netherlands.; Department of Cardiology, The Heart Centre, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.; Department of Forensic Medicine, Faculty of Medical Sciences, University of Copenhagen, Copenhagen, Denmark., van den Berg MP; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands., Olesen MS; Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark., Lambiase PD; Member of the European Reference Network for rare, low prevalence and/or complex diseases of the heart: ERN GUARD-Heart, Amsterdam, Netherlands.; Barts Heart Centre, Barts Health NHS Trust & Institute of Cardiovascular Science, University College London, London, United Kingdom., Borggrefe M; Department of Medicine, University Medical Center Mannheim, Mannheim, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Heidelberg/Mannheim, Mannheim, Germany., Hayashi K; Department of Cardiovascular Medicine, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Japan., Rydberg A; Member of the European Reference Network for rare, low prevalence and/or complex diseases of the heart: ERN GUARD-Heart, Amsterdam, Netherlands.; Department of Clinical Sciences, Paediatrics, Umeå University, Umeå, Sweden., Nakajima T; Department of Cardiovascular Medicine, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan., Yoshinaga M; Department of Pediatrics, National Hospital Organization Kagoshima Medical Center, Kagoshima, Japan., Saenen JB; Department of Cardiology, University of Antwerp, Antwerp University Hospital, Antwerp, Belgium., Kääb S; Department of Internal Medicine I, LMU Klinikum, Klinikum der Ludwig Maximilians Universität München, München, Germany.; German Centre for Cardiovascular Research (DZHK), Partner Site Munich, Munich Heart Alliance (MHA), Munich, Germany., Brugada P; Member of the European Reference Network for rare, low prevalence and/or complex diseases of the heart: ERN GUARD-Heart, Amsterdam, Netherlands.; Heart Rhythm Management Center, UZ Brussel-VUB, Brussels, Belgium., Robyns T; Member of the European Reference Network for rare, low prevalence and/or complex diseases of the heart: ERN GUARD-Heart, Amsterdam, Netherlands.; Department of Cardiovascular Diseases, University Hospitals Leuven, Leuven, Belgium., Giachino DF; Medical Genetics, San Luigi Univesity Hospital, Orbassano, TO, Italy.; Medical Genetics Department, Clinical and Biological Sciences, Univestity of Torino, Orbassano, TO, Italy., Ackerman MJ; Department of Cardiovascular Medicine, Division of Heart Rhythm Services, Mayo Clinic, Rochester, MN, USA., Brugada R; Hospital Trueta, CiberCV, University of Girona, IDIBGI, Girona, Spain., Brugada J; Cardiovascular Institute, Hospital Clinic, University of Barcelona, Barcelona, Spain., Gimeno JR; Member of the European Reference Network for rare, low prevalence and/or complex diseases of the heart: ERN GUARD-Heart, Amsterdam, Netherlands.; Inherited Cardiac Disease Unit, Cardiology Department, University Hospital Virgen de la Arrixaca, Murcia, Spain., Hasdemir C; Department of Cardiology, Ege University School of Medicine, Izmir, Turkey., Guicheney P; INSERM, Sorbonne University, UMRS 1166, Institute of Cardiometabolism and Nutrition (ICAN), Paris, France., Priori SG; Member of the European Reference Network for rare, low prevalence and/or complex diseases of the heart: ERN GUARD-Heart, Amsterdam, Netherlands.; Molecular Cardiology, ICS Maugeri, IRCCS and Department of Molecular Medicine, University of Pavia, Pavia, Italy., Schulze-Bahr E; Member of the European Reference Network for rare, low prevalence and/or complex diseases of the heart: ERN GUARD-Heart, Amsterdam, Netherlands.; Institute for Genetics of Heart Diseases, University Hospital Münster, Münster, Germany., Makita N; Omics Research Center, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan., Schwartz PJ; Istituto Auxologico Italiano, IRCCS-Center for Cardiac Arrhythmias of Genetic Origin, Milan, Italy.; Istituto Auxologico Italiano, IRCCS-Laboratory of Cardiovascular Genetics, Cusano Milanino, MI, Italy., Shimizu W; Department of Cardiovascular Medicine, Nippon Medical School, Tokyo, Japan., Aiba T; Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Japan., Schott JJ; Member of the European Reference Network for rare, low prevalence and/or complex diseases of the heart: ERN GUARD-Heart, Amsterdam, Netherlands.; Université de Nantes, CHU Nantes, CNRS, INSERM, l'institut du thorax, Nantes, France., Redon R; Member of the European Reference Network for rare, low prevalence and/or complex diseases of the heart: ERN GUARD-Heart, Amsterdam, Netherlands.; Université de Nantes, CHU Nantes, CNRS, INSERM, l'institut du thorax, Nantes, France., Ohno S; Department of Bioscience and Genetics, National Cerebral and Cardiovascular Center, Suita, Japan., Probst V; Member of the European Reference Network for rare, low prevalence and/or complex diseases of the heart: ERN GUARD-Heart, Amsterdam, Netherlands.; Université de Nantes, CHU Nantes, CNRS, INSERM, l'institut du thorax, Nantes, France., Behr ER; Member of the European Reference Network for rare, low prevalence and/or complex diseases of the heart: ERN GUARD-Heart, Amsterdam, Netherlands.; Molecular and Clinical Sciences Research Institute, St. George's, University of London, London, United Kingdom.; Cardiology Clinical Academic Group, St. George's University Hospitals' NHS Foundation Trust, London, United Kingdom., Barc J; Member of the European Reference Network for rare, low prevalence and/or complex diseases of the heart: ERN GUARD-Heart, Amsterdam, Netherlands.; Université de Nantes, CNRS, INSERM, l'institut du thorax, Nantes, France., Bezzina CR; Department of Clinical and Experimental Cardiology, Heart Centre, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.; Member of the European Reference Network for rare, low prevalence and/or complex diseases of the heart: ERN GUARD-Heart, Amsterdam, Netherlands.
Publikováno v:
Genetics in medicine : official journal of the American College of Medical Genetics [Genet Med] 2021 Jan; Vol. 23 (1), pp. 47-58. Date of Electronic Publication: 2020 Sep 07.
Genotype-phenotype relationship and risk stratification in loss-of-function SCN5A mutation carriers.
Autor:
Robyns T; Department of Cardiovascular Diseases, University Hospitals Leuven, Leuven, Belgium.; Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium., Nuyens D; Department of Cardiology, Ziekenhuis Oost Limburg, Genk, Belgium., Vandenberk B; Department of Cardiovascular Diseases, University Hospitals Leuven, Leuven, Belgium.; Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium., Kuiperi C; Department of Human Genetics, University Hospitals Leuven, Leuven, Belgium., Corveleyn A; Department of Human Genetics, University Hospitals Leuven, Leuven, Belgium., Breckpot J; Department of Human Genetics, University Hospitals Leuven, Leuven, Belgium., Garweg C; Department of Cardiovascular Diseases, University Hospitals Leuven, Leuven, Belgium.; Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium., Ector J; Department of Cardiovascular Diseases, University Hospitals Leuven, Leuven, Belgium.; Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium., Willems R; Department of Cardiovascular Diseases, University Hospitals Leuven, Leuven, Belgium.; Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium.
Publikováno v:
Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc [Ann Noninvasive Electrocardiol] 2018 Sep; Vol. 23 (5), pp. e12548. Date of Electronic Publication: 2018 Apr 30.
Autor:
Barc, Julien, Tadros, Rafik, Glinge, Charlotte, Chiang, David Y., Jouni, Mariam, Simonet, Floriane, Jurgens, Sean J., Baudic, Manon, Nicastro, Michele, Potet, Franck, Offerhaus, Joost A., Walsh, Roddy, Choi, Seung Hoan, Verkerk, Arie O., Mizusawa, Yuka, Anys, Soraya, Minois, Damien, Arnaud, Marine, Duchateau, Josselin, Wijeyeratne, Yanushi D., Muir, Alison, Papadakis, Michael, Castelletti, Silvia, Torchio, Margherita, Ortuño, Cristina Gil, Lacunza, Javier, Giachino, Daniela F., Cerrato, Natascia, Martins, Raphaël P., Campuzano, Oscar, Van Dooren, Sonia, Thollet, Aurélie, Kyndt, Florence, Mazzanti, Andrea, Clémenty, Nicolas, Bisson, Arnaud, Corveleyn, Anniek, Stallmeyer, Birgit, Dittmann, Sven, Saenen, Johan, Noël, Antoine, Honarbakhsh, Shohreh, Rudic, Boris, Marzak, Halim, Rowe, Matthew K., Federspiel, Claire, Le Page, Sophie, Placide, Leslie, Milhem, Antoine, Barajas-Martinez, Hector, Beckmann, Britt-Maria, Krapels, Ingrid P., Steinfurt, Johannes, Winkel, Bo Gregers, Jabbari, Reza, Shoemaker, Moore B., Boukens, Bas J., Škorić-Milosavljević, Doris, Bikker, Hennie, Manevy, Federico, Lichtner, Peter, Ribasés, Marta, Meitinger, Thomas, Müller-Nurasyid, Martina, Strauch, Konstantin, Peters, Annette, Schulz, Holger, Schwettmann, Lars, Leidl, Reiner, Heier, Margit, Veldink, Jan H., van den Berg, Leonard H., Van Damme, Philip, Cusi, Daniele, Lanzani, Chiara, Rigade, Sidwell, Charpentier, Eric, Baron, Estelle, Bonnaud, Stéphanie, Lecointe, Simon, Donnart, Audrey, Le Marec, Hervé, Chatel, Stéphanie, Karakachoff, Matilde, Bézieau, Stéphane, London, Barry, Tfelt-Hansen, Jacob, Roden, Dan, Odening, Katja E., Cerrone, Marina, Chinitz, Larry A., Volders, Paul G., van de Berg, Maarten P., Laurent, Gabriel, Faivre, Laurence, Antzelevitch, Charles, Kääb, Stefan, Arnaout, Alain Al, Dupuis, Jean-Marc, Pasquie, Jean-Luc, Billon, Olivier, Roberts, Jason D., Jesel, Laurence, Borggrefe, Martin, Lambiase, Pier D., Mansourati, Jacques, Loeys, Bart, Leenhardt, Antoine, Guicheney, Pascale, Maury, Philippe, Schulze-Bahr, Eric, Robyns, Tomas, Breckpot, Jeroen, Babuty, Dominique, Priori, Silvia G., Napolitano, Carlo, Defaye, Pascal, Anselme, Frédéric, Darmon, Jean Philippe, Wiart, François, de Asmundis, Carlo, Brugada, Pedro, Brugada, Ramon, Arbelo, Elena, Brugada, Josep, Mabo, Philippe, Behar, Nathalie, Giustetto, Carla, Molina, Maria Sabater, Gimeno, Juan R., Hasdemir, Can, Schwartz, Peter J., Crotti, Lia, McKeown, Pascal P., Sharma, Sanjay, Behr, Elijah R., Haissaguerre, Michel, Sacher, Frédéric, Rooryck, Caroline, Tan, Hanno L., Remme, Carol A., Postema, Pieter G., Delmar, Mario, Ellinor, Patrick T., Lubitz, Steven A., Gourraud, Jean-Baptiste, Tanck, Michael W., George, Alfred L., MacRae, Calum A., Burridge, Paul W., Dina, Christian, Probst, Vincent, Wilde, Arthur A., Schott, Jean-Jacques, Redon, Richard, Bezzina, Connie R.
Publikováno v:
Nat Genet
Nature Genetics
Nature genetics
KORA-Study Group & Nantes Referral Center for inherited cardiac arrhythmia 2022, ' Genome-wide association analyses identify new Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibility ', Nature Genetics, vol. 54, no. 3, pp. 232-239 . https://doi.org/10.1038/s41588-021-01007-6
Nature Genetics, 2022, 54 (3), pp.232-239. ⟨10.1038/s41588-021-01007-6⟩
Nat. Genet. 54, 232-239 (2022)
Nature genetics, 54(3), 232-239. Nature Publishing Group
Nature Genetics, 54(3), 232-239. Nature Publishing Group
Nature Genetics
Nature genetics
KORA-Study Group & Nantes Referral Center for inherited cardiac arrhythmia 2022, ' Genome-wide association analyses identify new Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibility ', Nature Genetics, vol. 54, no. 3, pp. 232-239 . https://doi.org/10.1038/s41588-021-01007-6
Nature Genetics, 2022, 54 (3), pp.232-239. ⟨10.1038/s41588-021-01007-6⟩
Nat. Genet. 54, 232-239 (2022)
Nature genetics, 54(3), 232-239. Nature Publishing Group
Nature Genetics, 54(3), 232-239. Nature Publishing Group
Brugada syndrome (BrS) is a cardiac arrhythmia disorder associated with sudden death in young adults. With the exception of SCN5A, encoding the cardiac sodium channel Na(V)1.5, susceptibility genes remain largely unknown. Here we performed a genome-w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a005ee4626291bd7923a30190df9c3ab
https://europepmc.org/articles/PMC9376964/
https://europepmc.org/articles/PMC9376964/
Autor:
Charles Antzelevitch, Ahmad S. Amin, Bo Gregers Winkel, Dan M. Roden, Stefan Kääb, Jonathan R. Skinner, Seiko Ohno, Julien Barc, Birgit Stallmeyer, Carla Giustetto, Connie R. Bezzina, Francesco Mazzarotto, Tomas Robyns, Carlo Napolitano, Stellan Mörner, Doris Škorić-Milosavljević, Sven Dittmann, Kenichiro Yamagata, Sonia Van Dooren, Anniek Corveleyn, Carlo de Asmundis, Ramon Brugada, K Usuda, Yuji Tanaka, Sven Zumhagen, Tadashi Nakajima, Johan Saenen, Elijah R. Behr, Hector Barajas-Martinez, Stéphane Bézieau, Masao Yoshinaga, Georgia Sarquella-Brugada, Paul G.A. Volders, Juan R. Gimeno, Lia Crotti, Charlotte Glinge, Andrea Mazzanti, Ingrid P.C. Krapels, Nicola Whiffin, Sebastian Clauss, Yoshiaki Kaneko, James S. Ware, Minoru Horie, Keiko Shimamoto, Isabelle Denjoy, Pieter G. Postema, Christian Krijger, Takeshi Aiba, Masahiko Kurabayashi, Pyotr G. Platonov, Regina Sebastiano, Cristina Gil Ortuño, Annika Rydberg, Roddy Walsh, Michael J. Ackerman, Hideki Itoh, M. Benjamin Shoemaker, Can Hasdemir, Pascale Guicheney, J. Martijn Bos, Frederic Sacher, Takeru Makiyama, Julieta Lazarte, Maarten P. van den Berg, Dominique Babuty, David J. Tester, Silvia Castelletti, Jacques Mansourati, Antoine Leenhardt, Paul A. van der Zwaag, Sanjay Sharma, Elena Arbelo, Candan Celen, Pier D. Lambiase, Maria Christina Kotta, Johannes Steinfurt, Jean-Baptiste Gourraud, Pedro Brugada, Wataru Shimizu, Josep Brugada, Jørgen K. Kanters, Eline A. Nannenberg, Silvia G. Priori, Mary N. Sheppard, Richard Redon, Morten S. Olesen, Jeroen Breckpot, Britt M. Beckmann, Naomasa Makita, Martin Borggrefe, Rafik Tadros, Jean-Jacques Schott, Jacob Tfelt-Hansen, Steven A. Lubitz, Hatice Şahin, Najim Lahrouchi, Michael Papadakis, Daisuke Hazeki, Kenshi Hayashi, Oscar Campuzano, Katja E. Odening, Federica Dagradi, Eric Schulze-Bahr, Boris Rudic, Hiroki Kimoto, Vincent Probst, Jason D. Roberts, Raphaël P. Martins, Bart Loeys, Daniela F. Giachino, F. Kyndt, Kimie Ohkubo, Taisuke Ishikawa, Catarina Lundin, Lut Van Laer, Patrick T. Ellinor, Maria Sabater Molina, Peter J. Schwartz, Annika Winbo
Publikováno v:
Nantes Referral Center for inherited cardiac arrhythmia 2021, ' Enhancing rare variant interpretation in inherited arrhythmias through quantitative analysis of consortium disease cohorts and population controls ', Genetics In Medicine, vol. 23, pp. 47–58 . https://doi.org/10.1038/s41436-020-00946-5
Genetics in Medicine
Genetics in Medicine, Nature Publishing Group, 2020, ⟨10.1038/s41436-020-⟩
Genetics in Medicine, 47-58. Nature Publishing Group
ISSUE=1;STARTPAGE=47;ENDPAGE=58;ISSN=1098-3600;TITLE=Genetics in Medicine
Genetics in medicine
Walsh, Roddy; Lahrouchi, Najim; Tadros, Rafik; Kyndt, Florence; Glinge, Charlotte; Postema, Pieter G; Amin, Ahmad S; Nannenberg, Eline A; Ware, James S; Whiffin, Nicola; Mazzarotto, Francesco; Škorić-Milosavljević, Doris; Krijger, Christian; Arbelo, Elena; Babuty, Dominique; Barajas-Martinez, Hector; Beckmann, Britt M; Bézieau, Stéphane; Bos, J Martijn; Breckpot, Jeroen; ... (2021). Enhancing rare variant interpretation in inherited arrhythmias through quantitative analysis of consortium disease cohorts and population controls. Genetics in medicine, 23(1), pp. 47-58. Springer Nature 10.1038/s41436-020-00946-5
Genetics in medicine, 23(1), 47-58. Lippincott Williams and Wilkins
Genetics in Medicine, 23(1), 47-58. Nature Publishing Group
Genetics in Medicine
Genetics in Medicine, Nature Publishing Group, 2020, ⟨10.1038/s41436-020-⟩
Genetics in Medicine, 47-58. Nature Publishing Group
ISSUE=1;STARTPAGE=47;ENDPAGE=58;ISSN=1098-3600;TITLE=Genetics in Medicine
Genetics in medicine
Walsh, Roddy; Lahrouchi, Najim; Tadros, Rafik; Kyndt, Florence; Glinge, Charlotte; Postema, Pieter G; Amin, Ahmad S; Nannenberg, Eline A; Ware, James S; Whiffin, Nicola; Mazzarotto, Francesco; Škorić-Milosavljević, Doris; Krijger, Christian; Arbelo, Elena; Babuty, Dominique; Barajas-Martinez, Hector; Beckmann, Britt M; Bézieau, Stéphane; Bos, J Martijn; Breckpot, Jeroen; ... (2021). Enhancing rare variant interpretation in inherited arrhythmias through quantitative analysis of consortium disease cohorts and population controls. Genetics in medicine, 23(1), pp. 47-58. Springer Nature 10.1038/s41436-020-00946-5
Genetics in medicine, 23(1), 47-58. Lippincott Williams and Wilkins
Genetics in Medicine, 23(1), 47-58. Nature Publishing Group
Purpose: Stringent variant interpretation guidelines can lead to high rates of variants of uncertain significance (VUS) for genetically heterogeneous disease like long QT syndrome (LQTS) and Brugada syndrome (BrS). Quantitative and disease-specific c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::193437f5ba4e2e30da09bd570e67f778
http://hdl.handle.net/10044/1/82315
http://hdl.handle.net/10044/1/82315