Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Neil G. Burnet"'
Autor:
Mukesh MB; Mukesh B. Mukesh, Gillian C. Barnett, Jennifer S. Wilkinson, Anne M. Moody, Charles Wilson, Wendi Qian, Nicola Twyman, Neil G. Burnet, and Charlotte E. Coles, Cambridge University Hospitals National Health Service Foundation Trust; Gillian C. Barnett, Charleen Chan Wah Hak, and Neil G. Burnet, University of Cambridge; and Gordon C. Wishart, Anglia Ruskin University, Cambridge, United Kingdom., Barnett GC, Wilkinson JS, Moody AM, Wilson C, Dorling L, Chan Wah Hak C, Qian W, Twyman N, Burnet NG, Wishart GC, Coles CE
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2013 Dec 20; Vol. 31 (36), pp. 4488-95. Date of Electronic Publication: 2013 Sep 16.
Autor:
Gillian C. Barnett, Sarah L. Kerns, Leila Dorling, Laura Fachal, Miguel E. Aguado-Barrera, Laura Martínez-Calvo, Harkeran K. Jandu, Ceilidh Welsh, Jonathan Tyrer, Charlotte E. Coles, Joanne S. Haviland, Christopher Parker, Antonio Gómez-Caamaño, Patricia Calvo-Crespo, Paloma Sosa-Fajardo, Neil G. Burnet, Holly Summersgill, Adam Webb, Dirk De Ruysscher, Petra Seibold, Jenny Chang-Claude, Christopher J. Talbot, Tim Rattay, Matthew Parliament, Kim De Ruyck, Barry S. Rosenstein, Paul D.P. Pharoah, Alison M. Dunning, Ana Vega, Catharine M.L. West
Publikováno v:
International Journal of Radiation Oncology Biology Physics, 114(3), 494-501. Elsevier Science
Purpose: Our aim was to test whether updated polygenic risk scores (PRS) for susceptibility to cancer affect risk of radiation therapy toxicity. Methods and Materials: Analyses included 9,717 patients with breast (n=3,078), prostate (n=5,748) or lung
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::195268f26e7f1840a9e2e97f2c194cb1
https://cris.maastrichtuniversity.nl/en/publications/ead33649-3701-47a7-afcd-c39bc9b00b93
https://cris.maastrichtuniversity.nl/en/publications/ead33649-3701-47a7-afcd-c39bc9b00b93
Autor:
Tomo Suga, Catharine M L West, Petra Seibold, Charlotte E. Coles, Marie-Luise Sautter-Bihl, Juergen Debus, C. Anne Koch, Christopher J. Talbot, Sabine Behrens, Gillian C. Barnett, John Yarnold, Frederik Wenz, Irmgard Helmbold, Judith M Bliss, Odilia Popanda, Alison M. Dunning, Neil G. Burnet, Barry S. Rosenstein, Katherine A. Vallis, Takashi Imai, R. Paul Symonds, Tim Rattay, Sarah L. Kerns, David Azria, Jenny Chang-Claude, Thomas Schnabel, Johannes Claßen, Céline Bourgier, Peter Schmezer
Publikováno v:
International Journal of Radiation Oncology-Biology-Physics
International Journal of Radiation Oncology-Biology-Physics, Elsevier, 2015, 92 (5), pp.1084-1092. ⟨10.1016/j.ijrobp.2015.04.011⟩
International Journal of Radiation Oncology-Biology-Physics, Elsevier, 2015, 92 (5), pp.1084-1092. ⟨10.1016/j.ijrobp.2015.04.011⟩
International audience; PURPOSE:To identify single-nucleotide polymorphisms (SNPs) in oxidative stress-related genes associated with risk of late toxicities in breast cancer patients receiving radiation therapy.METHODS AND MATERIALS:Using a 2-stage d
Autor:
Leila Dorling, A.M. Moody, W. Qian, Charles Wilson, Gordon C. Wishart, Charlotte E. Coles, Jennifer S. Wilkinson, Neil G. Burnet, N. Twyman, Gillian C. Barnett, M. Mukesh
Publikováno v:
Radiotherapy and Oncology. 111:270-275
The use of intensity-modulated radiotherapy (IMRT) in breast cancer reduces clinician-assessed breast tissue toxicity including fibrosis, telangectasia and sub-optimal cosmesis. Patient reported outcome measures (PROMs) are also important as they pro
Autor:
Christopher J. Talbot, Ana Vega, Paul D.P. Pharoah, Caroline Baynes, John Yarnold, Craig Luccarini, Laura Fachal, Rebecca Elliott, Sarah L. Gulliford, Kyriaki Michailidou, Matthew R. Sydes, Barry S. Rosenstein, Jonathan Tyrer, Jennifer Titley, Søren M. Bentzen, Catharine M L West, Alison M. Dunning, Deborah J. Thompson, Don M. Conroy, Charlotte E. Coles, Leila Dorling, Emma Hall, Rebecca Mayes, George A. Tanteles, Mel Maranian, Joanne S Haviland, Gillian C. Barnett, Neil G. Burnet, Radka Platte, Vivek Misra, Jennifer S. Wilkinson, Paul Symonds, Joe Dennis, David P. Dearnaley, Antonio Gómez-Caamaño, Sarah L. Kerns
Publikováno v:
RUNA. Repositorio da Consellería de Sanidade e Sergas
Servizo Galego de Saúde (SERGAS)
Servizo Galego de Saúde (SERGAS)
Background and purpose This study was designed to identify common single nucleotide polymorphisms (SNPs) associated with toxicity 2years after radiotherapy. Materials and methods A genome wide association study was performed in 1850 patients from the
Autor:
Jan Alsner, Sara Gutiérrez-Enríquez, R. Paul Symonds, Annette Raabe, Søren M. Bentzen, Maria J. Fuentes-Raspall, Petra Seibold, Gillian C. Barnett, Christian Nicolaj Andreassen, Neil G. Burnet, Christopher J. Talbot, Frederik Wenz, John Yarnold, Rebecca Elliott, Catharine M L West, Alison M. Dunning, Charlotte E. Coles, Jenny Chang-Claude, Maria C. Alonso-Muñoz, Osama Abdelhay, Jennifer S. Wilkinson, Barry S. Rosenstein, Sarah L. Kerns
Publikováno v:
RADIOTHERAPY AND ONCOLOGY
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Barnett, G C, Elliott, R M, Alsner, J, Andreassen, C N, Abdelhay, O, Burnet, N G, Chang-Claude, J, Coles, C E, Gutiérrez-Enríquez, S, Fuentes-Raspall, M J, Alonso-Muñoz, M C, Kerns, S, Raabe, A, Symonds, R P, Seibold, P, Talbot, C J, Wenz, F, Wilkinson, J, Yarnold, J, Dunning, A M, Rosenstein, B S, West, C M L & Bentzen, S M 2012, ' Individual patient data meta-analysis shows no association between the SNP rs1800469 in TGFB and late radiotherapy toxicity ', Radiotherapy & Oncology, vol. 105, no. 3, pp. 289-295 . https://doi.org/10.1016/j.radonc.2012.10.017
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Barnett, G C, Elliott, R M, Alsner, J, Andreassen, C N, Abdelhay, O, Burnet, N G, Chang-Claude, J, Coles, C E, Gutiérrez-Enríquez, S, Fuentes-Raspall, M J, Alonso-Muñoz, M C, Kerns, S, Raabe, A, Symonds, R P, Seibold, P, Talbot, C J, Wenz, F, Wilkinson, J, Yarnold, J, Dunning, A M, Rosenstein, B S, West, C M L & Bentzen, S M 2012, ' Individual patient data meta-analysis shows no association between the SNP rs1800469 in TGFB and late radiotherapy toxicity ', Radiotherapy & Oncology, vol. 105, no. 3, pp. 289-295 . https://doi.org/10.1016/j.radonc.2012.10.017
Background and purpose: Reported associations between risk of radiation-induced normal tissue injury and single nucleotide polymorphisms (SNPs) in TGFB1, encoding the pro-fibrotic cytokine transforming growth factor-beta 1 (TGF-beta 1), remain contro
Autor:
Agustin Barnadas, Harry Ostrer, Søren M. Bentzen, David Azria, Rebecca Elliott, C.A. Koch, John Yarnold, Petra Seibold, M. Molla, Christian Nicolaj Andreassen, Laura Fachal, Ana Vega, David P. Dearnaley, Emma Hall, Barry S. Rosenstein, Sarah L. Kerns, Michael Blackshaw, Piet Ost, Matthew Parliament, Marie Overgaard, Jamie A. Cesaretti, Catharine M L West, Teresa Ramón y Cajal, Michael Sia, Charlotte E. Coles, Orland Diez, Dirk De Ruysscher, Matthew R. Sydes, Jenny Chang-Claude, Antonio Gómez-Caamaño, Jan Alsner, Christopher J. Talbot, Maria J. Fuentes-Raspall, Odilia Popanda, Gillian C. Barnett, Jens Overgaard, Neil G. Burnet, Hubert Thierens, Leila Dorling, Sara Gutiérrez-Enríquez, R. Paul Symonds, Danny Vesprini, Alison M. Dunning, Kim De Ruyck
Publikováno v:
Radiotherapy and Oncology, 121(3), 431-439. Elsevier Ireland Ltd
Radiotherapy and Oncology
Radiotherapy and Oncology, Elsevier, 2016, 121 (3), pp.431-439. ⟨10.1016/j.radonc.2016.06.017⟩
RADIOTHERAPY AND ONCOLOGY
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Andreassen, C N, Rosenstein, B S, Kerns, S L, Ostrer, H, De Ruysscher, D, Cesaretti, J A, Barnett, G C, Dunning, A M, Dorling, L, West, C M L, Burnet, N G, Elliott, R, Coles, C, Hall, E, Fachal, L, Vega, A, Gómez-Caamaño, A, Talbot, C J, Symonds, R P, De Ruyck, K, Thierens, H, Ost, P, Chang-Claude, J, Seibold, P, Popanda, O, Overgaard, M, Dearnaley, D, Sydes, M R, Azria, D, Koch, C A, Parliament, M, Blackshaw, M, Sia, M, Fuentes-Raspall, M J, Ramon Y Cajal, T, Barnadas, A, Vesprini, D, Gutiérrez-Enríquez, S, Mollà, M, Díez, O, Yarnold, J R, Overgaard, J, Bentzen, S M, Alsner, J & International Radiogenomics Consortium (RgC) 2016, ' Individual patient data meta-analysis shows a significant association between the ATM rs1801516 SNP and toxicity after radiotherapy in 5456 breast and prostate cancer patients ', Radiotherapy and Oncology, vol. 121, no. 3, pp. 431-439 . https://doi.org/10.1016/j.radonc.2016.06.017
Andreassen, C N, Rosenstein, B S, Kerns, S L, Ostrer, H, De Ruysscher, D, Cesaretti, J A, Barnett, G C, Dunning, A M, Dorling, L, West, C M L, Burnet, N G, Elliott, R, Coles, C, Hall, E, Fachal, L, Vega, A, Gómez-Caamaño, A, Talbot, C J, Symonds, R P, De Ruyck, K, Thierens, H, Ost, P, Chang-Claude, J, Seibold, P, Popanda, O, Overgaard, M, Dearnaley, D, Sydes, M R, Azria, D, Koch, C A, Parliament, M, Blackshaw, M, Sia, M, Fuentes-Raspall, M J, Ramon Y Cajal, T, Barnadas, A, Vesprini, D, Gutiérrez-Enríquez, S, Mollà, M, Díez, O, Yarnold, J R, Overgaard, J, Bentzen, S M, Alsner, J & International Radiogenomics Consortium (RgC) 2016, ' Individual patient data meta-analysis shows a significant association between the ATM rs1801516 SNP and toxicity after radiotherapy in 5456 breast and prostate cancer patients ', Radiotherapy & Oncology . https://doi.org/10.1016/j.radonc.2016.06.017
Radiotherapy and Oncology
Radiotherapy and Oncology, Elsevier, 2016, 121 (3), pp.431-439. ⟨10.1016/j.radonc.2016.06.017⟩
RADIOTHERAPY AND ONCOLOGY
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Andreassen, C N, Rosenstein, B S, Kerns, S L, Ostrer, H, De Ruysscher, D, Cesaretti, J A, Barnett, G C, Dunning, A M, Dorling, L, West, C M L, Burnet, N G, Elliott, R, Coles, C, Hall, E, Fachal, L, Vega, A, Gómez-Caamaño, A, Talbot, C J, Symonds, R P, De Ruyck, K, Thierens, H, Ost, P, Chang-Claude, J, Seibold, P, Popanda, O, Overgaard, M, Dearnaley, D, Sydes, M R, Azria, D, Koch, C A, Parliament, M, Blackshaw, M, Sia, M, Fuentes-Raspall, M J, Ramon Y Cajal, T, Barnadas, A, Vesprini, D, Gutiérrez-Enríquez, S, Mollà, M, Díez, O, Yarnold, J R, Overgaard, J, Bentzen, S M, Alsner, J & International Radiogenomics Consortium (RgC) 2016, ' Individual patient data meta-analysis shows a significant association between the ATM rs1801516 SNP and toxicity after radiotherapy in 5456 breast and prostate cancer patients ', Radiotherapy and Oncology, vol. 121, no. 3, pp. 431-439 . https://doi.org/10.1016/j.radonc.2016.06.017
Andreassen, C N, Rosenstein, B S, Kerns, S L, Ostrer, H, De Ruysscher, D, Cesaretti, J A, Barnett, G C, Dunning, A M, Dorling, L, West, C M L, Burnet, N G, Elliott, R, Coles, C, Hall, E, Fachal, L, Vega, A, Gómez-Caamaño, A, Talbot, C J, Symonds, R P, De Ruyck, K, Thierens, H, Ost, P, Chang-Claude, J, Seibold, P, Popanda, O, Overgaard, M, Dearnaley, D, Sydes, M R, Azria, D, Koch, C A, Parliament, M, Blackshaw, M, Sia, M, Fuentes-Raspall, M J, Ramon Y Cajal, T, Barnadas, A, Vesprini, D, Gutiérrez-Enríquez, S, Mollà, M, Díez, O, Yarnold, J R, Overgaard, J, Bentzen, S M, Alsner, J & International Radiogenomics Consortium (RgC) 2016, ' Individual patient data meta-analysis shows a significant association between the ATM rs1801516 SNP and toxicity after radiotherapy in 5456 breast and prostate cancer patients ', Radiotherapy & Oncology . https://doi.org/10.1016/j.radonc.2016.06.017
Purpose: Several small studies have indicated that the ATM rsl 801516 SNP is associated with risk of normal tissue toxicity after radiotherapy. However, the findings have not been consistent. In order to test this SNP in a well-powered study, an indi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed3c24daed41f38a52930d0eada05be2
https://europepmc.org/articles/PMC5559879/
https://europepmc.org/articles/PMC5559879/
Autor:
George A. Tanteles, Christopher J. Talbot, R P Symonds, John Yarnold, Jenny Chang-Claude, Alison M. Dunning, Odilia Popanda, Catharine M L West, Neil G. Burnet, Charlotte E. Coles, Robert J.S. Murray, Petra Seibold, Susan E Davidson, J. Mills, Gillian C. Barnett
Publikováno v:
British Journal of Cancer
Background: Response to radiotherapy varies between individuals both in terms of efficacy and adverse reactions. Finding genetic determinants of radiation response would allow the tailoring of the treatment, either by altering the radiation dose or b
Autor:
Rebecca Elliott, Kyriaki Michailidou, Gillian C. Barnett, Alison M. Dunning, Paul D.P. Pharoah, Catharine M L West, John Yarnold, Leila Dorling, Charlotte E. Coles, Neil G. Burnet
Publikováno v:
Clinical Cancer Research
Dorling, L, Barnett, G C, Michailidou, K, Coles, C E, Burnet, N G, Yarnold, J, Elliott, R M, Dunning, A M, Pharoah, P D P & West, C M 2016, ' Patients with a High Polygenic Risk of Breast Cancer do not have An Increased Risk of Radiotherapy Toxicity ', Clinical Cancer Research, vol. 22, no. 6, pp. 1413-1420 . https://doi.org/10.1158/1078-0432.CCR-15-1080, https://doi.org/10.1158/1078-0432.CCR-15-1080
Dorling, L, Barnett, G C, Michailidou, K, Coles, C E, Burnet, N G, Yarnold, J, Elliott, R M, Dunning, A M, Pharoah, P D P & West, C M 2016, ' Patients with a High Polygenic Risk of Breast Cancer do not have An Increased Risk of Radiotherapy Toxicity ', Clinical Cancer Research, vol. 22, no. 6, pp. 1413-1420 . https://doi.org/10.1158/1078-0432.CCR-15-1080, https://doi.org/10.1158/1078-0432.CCR-15-1080
Purpose: It has been hypothesized that increased predisposition to breast cancer may correlate with radiosensitivity, and thus increased risk of toxicity following breast irradiation. This study investigated the relationship between common breast can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6574efe309943cb31817072c2ef5138e
https://europepmc.org/articles/PMC4751620/
https://europepmc.org/articles/PMC4751620/
Autor:
Neil G. Burnet, Gillian C. Barnett, Paul D.P. Pharoah, Alison M. Dunning, Rebecca Elliott, Caroline Baynes, Catharine M L West, Charlotte E. Coles, Jennifer S. Wilkinson
Publikováno v:
Radiotherapy and Oncology. 97:9-14
Several small studies have reported associations between TGFB1 single nucleotide polymorphisms (SNPs), considered to increase secretion of TGF-β1, and greater than 3-fold increases in incidence of fibrosis - an indicator of late toxicity after radio