Zobrazeno 1 - 10
of 408
pro vyhledávání: '"Michael Untch"'
Autor:
Mattea Reinisch, Michael Untch, Rolf Mahlberg, Toralf Reimer, Thomas Hitschold, Frederik Marmé, Mustafa Aydogdu, Sabine Schmatloch, Hans-Joachim Lück, Marcus Schmidt, Ekkehart Ladda, Bruno Valentin Sinn, Peter Klare, Wolfgang Janni, Christian Jackisch, Carsten Denkert, Sabine Seiler, Thomas Göhler, Laura Michel, Nicole Burchardi, Elmar Stickeler, Julia Rey, Nicole Klutinus, Volker Möbus, Sibylle Loibl
Publikováno v:
Breast, Vol 66, Iss , Pp 110-117 (2022)
Background: Trastuzumab given intravenously in combination with chemotherapy is standard of care for patients with early HER2-positive breast cancer (BC). Different randomised studies have shown equivalent efficacy of a subcutaneous injection into th
Externí odkaz:
https://doaj.org/article/916f38f5626a45b9afb718606995934e
Autor:
Melitta Beatrice Köpke, Carl Mathis Wild, Mariella Schneider, Nicole Pochert, Felicitas Schneider, Jacqueline Sagasser, Thorsten Kühn, Michael Untch, Christian Hinske, Matthias Reiger, Claudia Traidl-Hoffmann, Christian Dannecker, Udo Jeschke, Nina Ditsch
Publikováno v:
Cancers, Vol 15, Iss 14, p 3606 (2023)
The collective of the SerMa pilot study included 100 cases of primary breast cancer or Carcinoma in situ who had undergone a mastectomy procedure with or without reconstruction of the breast using an implant or expander at Augsburg University Hospita
Externí odkaz:
https://doaj.org/article/b6daf09bd99f47b38aae5c91646f7528
Autor:
Elena Laakmann, Isabell Witzel, Peter A. Fasching, Mahdi Rezai, Christian Schem, Christine Solbach, Hans Tesch, Peter Klare, Andreas Schneeweiss, Christoph Salat, Dirk-Michael Zahm, Jens-Uwe Blohmer, Barbara Ingold-Heppner, Jens Huober, Claus Hanusch, Christian Jackisch, Mattea Reinisch, Michael Untch, Gunter von Minckwitz, Valentina Nekljudova, Volkmar Müller, Sibylle Loibl
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-8 (2019)
Abstract Background The incidence of central nervous system (CNS) metastases in breast cancer patients is rising and has become a major clinical challenge. Only few data are published concerning risk factors for the development of CNS metastases as a
Externí odkaz:
https://doaj.org/article/917ee11fdd924b59b741e34137515454
Autor:
Ines Stevic, Volkmar Müller, Karsten Weber, Peter A. Fasching, Thomas Karn, Frederic Marmé, Christian Schem, Elmar Stickeler, Carsten Denkert, Marion van Mackelenbergh, Christoph Salat, Andreas Schneeweiss, Klaus Pantel, Sibylle Loibl, Michael Untch, Heidi Schwarzenbach
Publikováno v:
BMC Medicine, Vol 16, Iss 1, Pp 1-16 (2018)
Abstract Background The focus of this study is to identify particular microRNA (miRNA) signatures in exosomes derived from plasma of 435 human epidermal growth factor receptor 2 (HER2)-positive and triple-negative (TN) subtypes of breast cancer (BC).
Externí odkaz:
https://doaj.org/article/c1482c9d621c46d29991f47cf0bdb872
Autor:
Bernd Gerber, Andreas Schneeweiss, Volker Möbus, Michael Golatta, Hans Tesch, David Krug, Claus Hanusch, Carsten Denkert, Kristina Lübbe, Jörg Heil, Jens Huober, Beyhan Ataseven, Peter Klare, Markus Hahn, Michael Untch, Karin Kast, Christian Jackisch, Jörg Thomalla, Fenja Seither, Jens-Uwe Blohmer, Kerstin Rhiem, Peter A. Fasching, Valentina Nekljudova, Sibylle Loibl, Thorsten Kühn
Publikováno v:
Cancers, Vol 14, Iss 3, p 521 (2022)
Background: The conversion of initially histologically confirmed axillary lymph node-positive (pN+) to ypN0 after neoadjuvant systemic treatment (NAST) is an important prognostic factor in breast cancer (BC) patients and may influence surgical de-esc
Externí odkaz:
https://doaj.org/article/17e84cdca4604002ae0a7a1cf9a85dd2
Autor:
Serena Di Cosimo, Valentina Appierto, Sara Pizzamiglio, Marco Silvestri, José Baselga, Martine Piccart, Jens Huober, Miguel Izquierdo, Lorena de la Pena, Florentine S. Hilbers, Evandro de Azambuja, Michael Untch, Lajos Pusztai, Kathleen Pritchard, Paolo Nuciforo, Anne Vincent-Salomon, Fraser Symmans, Giovanni Apolone, Filippo G. de Braud, Marilena V. Iorio, Paolo Verderio, Maria Grazia Daidone
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 4, p 1386 (2020)
Circulating microRNA (ct-miRNAs) are able to identify patients with differential response to HER2-targeted therapy. However, their dynamics are largely unknown. We assessed 752 miRNAs from 52 NeoALTTO patients with plasma pairs prior and two weeks af
Externí odkaz:
https://doaj.org/article/c17c91ee4a3944f1a25b0f0df0cf277b
Autor:
Malgorzata Banys-Paluchowski, Sibylle Loibl, Isabell Witzel, Christoph Mundhenke, Bianca Lederer, Christine Solbach, Thomas Karn, Frederik Marmé, Valentina Nekljudova, Christian Schem, Elmar Stickeler, Nicholas Willumsen, Morten A. Karsdal, Michael Untch, Volkmar Müller
Publikováno v:
Cancers, Vol 11, Iss 8, p 1186 (2019)
Background: Remodeling of extracellular matrix through collagen degradation is a crucial step in the metastatic cascade. The aim of this study was to evaluate the potential clinical relevance of the serum collagen degradation markers (CDM) C3M and C4
Externí odkaz:
https://doaj.org/article/b64d57df09ef4879919b5a3bcd99c794
Autor:
Toralf Reimer, Wolfgang Janni, Hans Tesch, Kristina Lübbe, Theresa Link, Carsten Denkert, Marianne Just, Jenny Furlanetto, Frederik Marmé, Erich Solomayer, Christian Jackisch, Wolfgang D. Schmitt, Kerstin Rhiem, Mattea Reinisch, Fenja Seither, A Forberger, Peter A. Fasching, Bruno Valentin Sinn, Michael Untch, Sibylle Loibl, Claus Hanusch, Valentina Nekljudova, Christine Solbach, Jens-Uwe Blohmer, Sabine Seiler, Sabine Schmatloch, Andreas Schneeweiss, Elmar Stickeler, Pauline Wimberger, Jens Huober, Marcus Schmidt, Laura Michel, Oliver Stötzer, Eric Hahnen
Publikováno v:
The Lancet Oncology. 22:1151-1161
Summary Background The development of anti-HER2 antibody–drug conjugates opens new therapeutic options for patients with breast cancer, including patients with low expression of HER2. To characterise this new breast cancer subtype, we have compared
Autor:
David Krug, Tanja Fehm, Manfred Welslau, Wolfgang Janni, Florian Schütz, Diana Lüftner, Christoph Thomssen, Elmar Stickeler, Rachel Würstlein, Annika Behrens, Marc Thill, Michael Untch, Andreas D. Hartkopf, Erik Belleville, Simon Bader, Peter A. Fasching, Volkmar Müller, Cornelia Kolberg-Liedtke, Hans-Christian Kolberg
Publikováno v:
Geburtshilfe und Frauenheilkunde
The continuous availability of findings from new studies repeatedly results in updated treatment recommendations and guidelines. In the case of breast carcinoma in particular, several studies have been published in the last few years that have transf
Autor:
Bianca Lederer, Arndt Hartmann, Hans Ulrich Ulmer, Wolfgang D. Schmitt, Sonia L. Villegas, Jutta Engel, Frank Holms, Andreas Schneeweiss, Bruno Valentin Sinn, Claus Hanusch, Michael Untch, Karsten Weber, Valentina Nekljudova, Marion van Mackelenbergh, Frederik Marmé, Hans Tesch, Clemens Heinrichs, Christian Albig, John Hackmann, Jens Huober, Christian Jackisch, Marion Kiechle, Nicole Pfarr, Wilko Weichert, Mahdi Rezai, Simone Schrodi, Carsten Denkert, Peter A. Fasching, Peter Sinn, Sibylle Loibl
Publikováno v:
European Journal of Cancer. 148:159-170
AIM To evaluate HER2-negative breast cancer (BC) with a low hormone receptor (HR) expression, with regard to pathological complete response (pCR) and survival, in comparison to triple-negative BC (TNBC) and strong HR-positive BC. METHODS We compared