Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Nikol Mladkova"'
Publikováno v:
Expert Opinion on Investigational Drugs. 28:787-797
Introduction: Glioblastoma multiforme (GBM) is the most common primary malignant brain tumor in adults, but its prognosis remains poor despite significant advances in our understanding of its molecular biology and investigation of numerous treatment
Autor:
Erica Hlavin Bell, Nikol Mladkova, Aline Paixão Becker, Kevin Liu, Linlin Yang, Rameen Beroukhim, Marjolein Geurts, Keith L. Ligon, Ziyan Liu, Joseph P. McElroy, Tiantian Cui, S Jaharul Haque, Arnab Chakravarti, Pooja Manchanda Gulati, Jill S. Barnholtz-Sloan, Ashley Gray, Jessica Fleming, Pierre A. Robe
Publikováno v:
Oncogene. 38:2923-2936
Glioblastomas (GBMs) are the most aggressive primary brain tumors, with an average survival of less than 15 months. Therefore, there is a critical need to develop novel therapeutic strategies for GBM. This study aimed to assess the prognostic value o
Autor:
Darell D. Bigner, Kang Chunsheng, James Lin, Miriam V. Rivas, David Cory Adamson, Chunhui Di, Nikol Mladkova, Brian E. Fee
Publikováno v:
International Journal of Oncology
Glioblastoma multiforme (GBM) is one of the most common primary malignant brain tumors. Unraveling the molecular and genetic complexity that determines GBM's pronounced migratory property could provide new options for therapeutic targeting that may s
Publikováno v:
Molecular Diagnosis & Therapy. 12:199-208
Gliomas are the most common primary brain tumors in adults. Anaplastic astrocytoma and glioblastoma multiforme represent malignant astrocytomas, which are the most common type of malignant gliomas. Despite research efforts in cancer therapy, the prog
Autor:
Martino Monteverde, Karin J. Purdie, Marco Merlano, C. Lo Nigro, Tim Crook, Peter W. Szlosarek, Gareth J. Inman, Laura Lattanzio, Nikol Mladkova, C. Fleming, Catherine A. Harwood, Daniele Bergamaschi, Angela McHugh, Alastair M. Thompson, Charlotte M. Proby, Eleftheria Hatzimichael, N. Syed, Hexiao Wang, Irene M. Leigh, S. Lee, Rubeta N Matin, Evangelos Briasoulis, Andrew Evans
Publikováno v:
British Journal of Cancer
Background:Novel prognostic biomarkers and therapeutic strategies are urgently required for malignant melanoma. Ecto-5-prime-nucleotidase (NT5E; CD73) overexpression has been reported in several human cancers. The mechanism(s) underlying deregulated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36bc3fd8c109d83e0339c80d236ff912
http://hdl.handle.net/10044/1/82273
http://hdl.handle.net/10044/1/82273
Autor:
Nikol Mladkova, Arnab Chakravarti
Publikováno v:
Current oncology reports. 11(1)
The purpose of this review is to provide an up-to-date summary of the current knowledge and understanding of the molecular alterations and pathways relevant to the clinical outcome of glioblastoma patients and their potential use in designing persona