Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jeffrey E. DeClue"'
Autor:
Hongzhen Li, Peter B. Crino, Wen Li, David H. Gutmann, Erik J. Uhlmann, Jeffrey E. DeClue, Kevin C. Ess
Publikováno v:
Glia. 46:28-40
Individuals with tuberous sclerosis complex (TSC) exhibit a variety of neurologic abnormalities, including mental retardation, epilepsy, and autism. Examination of human TSC brains demonstrate dysplastic astrocytes and neurons, areas of abnormal neur
Autor:
Alex G. Papageorge, Douglas R. Lowy, Jeffrey E. DeClue, Xiaolan Qian, Pieter H. Anborgh, William C. Vass
Publikováno v:
Molecular and Cellular Biology. 19:4611-4622
Ras GTPases, which play a pivotal role as transducers of various mitogenic and differentiation signals, function as molecular switches, cycling between an inactive GDP-bound state and an active GTP-bound state (33). Ras is negatively regulated by GTP
Autor:
Jessica K. Emelin, Jeffrey E. DeClue, Christopher Kerfoot, Steven N. Roper, Michael Catania, Harry V. Vinters
Publikováno v:
Epilepsy research. 32(1-2)
Cortical dysplasia (CD) broadly defines a complex cerebral malformative lesion associated clinically with intractable, pharmacoresistant epilepsy (including infantile spasms), especially in infants and children. In CD, the spectrum of structural brai
Autor:
Jeffrey E. DeClue, Harry V. Vinters, Michael J. De Rosa, Vadims Poukens, Ralf Wienecke, Samuel H. Pepkowitz, Christopher Kerfoot, Sung Hye Park
Publikováno v:
Acta neuropathologica. 94(2)
We report an autopsy case of tuberous sclerosis complex (TSC) in a 20-week gestational age female fetus. The brain showed lesions suggestive of early cortical tubers and subependymal hamartomatous nodules. The large cells within these nodular cluster
Autor:
Cynthia T. Welsh, Ralf Wienecke, John C. Maize, Michael Menchine, Margaret G. Norman, Harry V. Vinters, Jeffrey E. DeClue, Christopher Kerfoot, Jessica K. Emelin
Publikováno v:
Brain pathology (Zurich, Switzerland). 6(4)
Tuberous sclerosis (TSC), an autosomal dominant disorder, is characterized by malformations, hamartomas and tumors in various organs including the brain. TSC is genetically linked to two loci: TSC1 on chromosome 9q34 and TSC2 on 16p13.3. TSC2 has bee