Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Caroline Graff"'
Autor:
Sandro Sorbi, Vince D. Calhoun, James B. Rowe, Isabelle Le Ber, Matthis Synofzik, Roberto Gasparotti, Martina Bocchetta, Enrico Premi, Dave Cash, Alexandre de Mendonça, Armin Iraji, Johannes Levin, Stefano Gazzina, A. Danek, Lize C. Jiskoot, Marcello Giunta, Alexander Gerhard, Markus Otto, Raquel Sánchez-Valle, Emily Todd, Genetic Frontotemporal dementia Initiative, Isabel Santana, Silvana Archetti, Rhian S Convery, Robert Laforce, Srinivas Rachakonda, Florence Pasquier, Fermin Moreno, John C. van Swieten, Georgia Peakman, Elizabeth Finger, Jonathan D. Rohrer, Christopher C Butler, Daniela Galimberti, Alberto Benussi, Carmela Tartaglia, Rik Vandenberghe, Caroline Graff, Mario Masellis, Fabrizio Tagliavini, Barbara Borroni, Simon Ducharme
Publikováno v:
Neurobiology of Aging, 108, 155-167. Elsevier Inc.
The presymptomatic brain changes of granulin (GRN) disease, preceding by years frontotemporal dementia, has not been fully characterized. New approaches focus on the spatial chronnectome can capture both spatial network configurations and their dynam
Autor:
Carlo Condello, Alison M. Maxwell, Erika Castillo, Atsushi Aoyagi, Caroline Graff, Martin Ingelsson, Lars Lannfelt, Thomas D. Bird, C. Dirk Keene, William W. Seeley, Daniel P. Perl, Elizabeth Head, Stanley B. Prusiner
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 119, iss 46
Down syndrome (DS) is caused by the triplication of chromosome 21 and is the most common chromosomal disorder in humans. Those individuals with DS who live beyond age 40 y develop a progressive dementia that is similar to Alzheimer’s disease (AD).
Autor:
Yang Yang, Wenjuan Zhang, Alexey G. Murzin, Manuel Schweighauser, Melissa Huang, Sofia Lövestam, Sew Y. Peak-Chew, Takashi Saito, Takaomi C. Saido, Jennifer Macdonald, Isabelle Lavenir, Bernardino Ghetti, Caroline Graff, Amit Kumar, Agneta Nordberg, Michel Goedert, Sjors H. W. Scheres
Publikováno v:
Acta neuropathologica.
Funder: Biotechnology and Biological Sciences Research Council; doi: http://dx.doi.org/10.13039/501100000268
The Arctic mutation, encoding E693G in the amyloid precursor protein (APP) gene [E22G in amyloid-β (Aβ)], causes dominantly inherited
The Arctic mutation, encoding E693G in the amyloid precursor protein (APP) gene [E22G in amyloid-β (Aβ)], causes dominantly inherited
Autor:
Matthis Synofzik, Alexandre de Mendonça, Giovanni B. Frisoni, Maura Malpetti, Fermin Moreno, Christopher C Butler, Roberta Ghidoni, Daniela Galimberti, Rik Vandenberghe, Elizabeth Finger, Isabel Santana, Alexander Gerhard, Georgia Peakman, Emily Todd, Carolin Heller, Jonathan D. Rohrer, Katrina M. Moore, Kamen A. Tsvetanov, Rhian S Convery, P. Simon Jones, Johannes Levin, James B. Rowe, Caroline Graff, Markus Otto, Barbara Borroni, Raquel Sánchez-Valle, Sandro Sorbi, Fabrizio Tagliavini, John C. van Swieten, Maria Carmela Tartaglia, Rogier A. Kievit, Simon Ducharme, Robert Laforce, Mario Masellis, Timothy Rittman, Adrian Danek, David M. Cash, Martina Bocchetta
Publikováno v:
Alzheimer's & Dementia
Alzheimer's and dementia 17(6), 969-983 (2021). doi:10.1002/alz.12252
Alzheimer's and Dementia, 17(6), 969-983. Elsevier Inc.
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Alzheimer's & Dementia, 17, 6, pp. 969-983
Alzheimer's & Dementia, 17, 969-983
Alzheimer's and dementia 17(6), 969-983 (2021). doi:10.1002/alz.12252
Alzheimer's and Dementia, 17(6), 969-983. Elsevier Inc.
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Alzheimer's & Dementia, 17, 6, pp. 969-983
Alzheimer's & Dementia, 17, 969-983
© 2020 The Authors. Alzheimer's & Dementia published by Wiley Periodicals LLC on behalf of Alzheimer's Association. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and repro
Autor:
Yolande A.L. Pijnenburg, Alessandro Padovani, Lieke H.H. Meeter, Rita Guerreiro, Mathieu Vandenbulcke, Rose Bruffaerts, Sonja Schönecker, Sofia Bergström, Florence Pasquier, Mikel Tainta, Beatriz Santiago, Roberto Gasparotti, Maria Rosário Almeida, Núria Bargalló, Abbe Ullgren, Martina Bocchetta, James B. Rowe, Pietro Tiraboschi, Robart Bartha, Rachelle Shafei, Benjamin Bender, Anna Månberg, Enrico Premi, Sergi Borrego-Écija, Sandro Sorbi, Christopher C Butler, Rick van Minkelen, Alberto Benussi, Marta Cañada, Carlo Wilke, Christin Andersson, Caroline Graff, Isabel Santana, Elisa Semler, Valentina Bessi, Miren Zulaica, Benedetta Nacmias, Tobias Langheinrich, Christen Shoesmith, Philip Van Damme, Camilla Ferrari, Martin Rosser, Pedro Rosa-Neto, Alexandre de Mendonça, Jennifer M. Nicholas, Catharina Prix, Sebastien Ourselin, Michele Veldsman, Jessica L. Panman, Håkan Thonberg, Jennie Olofsson, Paul M. Thompson, Ana Gorostidi, Andrea Arighi, Raquel Sánchez-Valle, Anna Antonell, Vesna Jelic, Ana Verdelho, Sara Mitchell, Janne M. Papma, Alina Díez, Giuliano Binetti, Rhian S Convery, Silvana Archetti, Ekaterina Rogaeva, Michela Pievani, C. Ferreira, Hans-Otto Karnath, Veronica Redaelli, Giuseppe Di Fede, Giovanni B. Frisoni, Carolina Maruta, Giacomina Rossi, Jaume Olives, Simon Ducharme, Roberta Ghidoni, Alexander Gerhard, Ron Keren, Johannes Levin, Sandra V. Loosli, Jose Bras, Isabelle Le Ber, Emily Todd, Robert Laforce, Sónia Afonso, Matthis Synofzik, Alazne Gabilondo, Elizabeth Finger, Thomas E. Cope, Paola Caroppo, Jorge Villanua, Diana Duro, Georgia Peakman, Giorgio G. Fumagalli, Serge Gauthier, Mario Masellis, Markus Otto, Caroline V. Greaves, Carolyn Timberlake, Harro Seelaar, Ione O.C. Woollacott, Sara Prioni, Jason D. Warren, Cristina Polito, Miguel Tábuas-Pereira, David F. Tang-Wai, Carmela Tartaglia, Linn Öijerstedt, Luisa Benussi, Barbara Borroni, Ricardo Taipa, Albert Lladó, Mircea Balasa, Rosa Rademakers, Lize C. Jiskoot, Miguel Castelo-Branco, Julia Remnestål, Fabrizio Tagliavini, Giorgio Giaccone, Maria João Leitão, Henrik Zetterberg, Valentina Cantoni, Daniela Galimberti, Sarah Anderl-Straub, Simon Mead, Myriam Barandiaran, Adrian Danek, Timothy Rittman, Chiara Fenoglio, Katrina M. Moore, David M. Cash, Rik Vandenberghe, Peter Nilsson, Elisabeth Wlasich, John C. van Swieten, Morris Freedman, Sandra E. Black, Carolin Heller, Stefano Gazzina, Gabriel Miltenberger, Fermin Moreno, Nick C. Fox, David L. Thomas, Jonathan D. Rohrer, Begoña Indakoetxea, Tobias Hoegen, Gemma Lombardi, Elio Scarpini
Publikováno v:
MOLECULAR NEURODEGENERATION, 16(1):79. BioMed Central
Molecular Neurodegeneration
Molecular Neurodegeneration, Vol 16, Iss 1, Pp 1-14 (2021)
Molecular Neurodegeneration, 16(1):79. BioMed Central Ltd.
Molecular neurodegeneration 16(1), 79 (2021). doi:10.1186/s13024-021-00499-4
on behalf of the Genetic Frontotemporal Dementia Initiative (GENFI) 2021, ' A panel of CSF proteins separates genetic frontotemporal dementia from presymptomatic mutation carriers : a GENFI study ', MOLECULAR NEURODEGENERATION, vol. 16, no. 1, 79 . https://doi.org/10.1186/s13024-021-00499-4
Molecular Neurodegeneration
Molecular Neurodegeneration, Vol 16, Iss 1, Pp 1-14 (2021)
Molecular Neurodegeneration, 16(1):79. BioMed Central Ltd.
Molecular neurodegeneration 16(1), 79 (2021). doi:10.1186/s13024-021-00499-4
on behalf of the Genetic Frontotemporal Dementia Initiative (GENFI) 2021, ' A panel of CSF proteins separates genetic frontotemporal dementia from presymptomatic mutation carriers : a GENFI study ', MOLECULAR NEURODEGENERATION, vol. 16, no. 1, 79 . https://doi.org/10.1186/s13024-021-00499-4
Availability of data and materials: The datasets used and/or analysed during the current study are available from the corresponding author on reasonable request. Supplementary Information: Additional file 1 of A panel of CSF proteins separates geneti
Autor:
Behzad, Khoshnood, Abbe, Ullgren, Jose, Laffita-Mesa, Linn, Öijerstedt, Kalicharan, Patra, Inger, Nennesmo, Caroline, Graff
Publikováno v:
Journal of neurology. 269(6)
Frontotemporal dementia (FTD) is a neurodegenerative disease, resulting in progressive problems in language and/or behaviour and is often diagnosed before 65 years of age. Ubiquitin positive protein aggregates in the brain are among the key pathologi
Autor:
Laetitia, Lemoine, Per-Göran, Gillberg, Nenad, Bogdanovic, Inger, Nennesmo, Laure, Saint-Aubert, Matti, Viitanen, Caroline, Graff, Martin, Ingelsson, Agneta, Nordberg
Publikováno v:
Molecular Psychiatry
Autosomal-dominant Alzheimer’s disease (ADAD) may be associated with atypical amyloid beta deposits in the brain. In vivo amyloid imaging using 11C-Pittsburgh compound B (PiB) tracer has shown differences in binding between brains from ADAD and spo
Autor:
Leila Sellami, Maria Carmela Tartaglia, John C. van Swieten, Giovanni B. Frisoni, Genfi Genetic Ftd Initiative, Alexandre de Mendonça, Jason D. Warren, Mario Masellis, Sandro Sorbi, James B. Rowe, E Finger, Fabrizio Tagliavini, Martina Bocchetta, Robert Laforce, Caroline Graff, Barbara Borroni, Katrina M. Dick, David M. Cash, Daniela Galimberti, Jonathan D. Rohrer
Publikováno v:
Journal of Alzheimers Disease, 65(1), 147-163. IOS Press BV
Journal of Alzheimer's Disease, Vol. 65, No 1 (2018) pp. 147-163
Journal of Alzheimer's Disease
Journal of Alzheimer's Disease, Vol. 65, No 1 (2018) pp. 147-163
Journal of Alzheimer's Disease
Background: The overlap between frontotemporal dementia (FTD) and primary psychiatric disorders has been brought to light by reports of prominent neuropsychiatric symptoms (NPS) in FTD-related genetic mutations, particularly among C9orf72 and GRN car
Autor:
Ove Almkvist, Anne Kinhult Ståhlbom, Lars-Olof Wahlund, Caroline Graff, Xiaozhen Li, Steinunn Thordardottir, Eric Westman, Kaj Blennow
Publikováno v:
Journal of Alzheimer's Disease. 56:327-334
Familial Alzheimer's disease (FAD) mutations have very high penetrance but age at onset and rate of disease progression differ. Neuroimaging and cerebrospinal fluid (CSF) examinations in mutation carriers (MCs) may provide an opportunity to identify
Autor:
Eduard, Vilaplana, Elena, Rodriguez-Vieitez, Daniel, Ferreira, Victor, Montal, Ove, Almkvist, Anders, Wall, Alberto, Lleó, Eric, Westman, Caroline, Graff, Juan, Fortea, Agneta, Nordberg
Publikováno v:
Neurology
Objective To study the macrostructural and microstructural MRI correlates of brain astrocytosis, measured with 11C-deuterium-L-deprenyl (11C-DED)–PET, in familial autosomal-dominant Alzheimer disease (ADAD). Methods The total sample (n = 31) compri