Zobrazeno 1 - 10
of 10
pro vyhledávání: '"C. Shan Xu"'
Autor:
Zhiyuan Lu, C. Shan Xu, Kenneth J. Hayworth, Song Pang, Kazunori Shinomiya, Stephen M. Plaza, Louis K. Scheffer, Gerald M. Rubin, Harald F. Hess, Patricia K. Rivlin, Ian A. Meinertzhagen
Publikováno v:
Frontiers in Neural Circuits, Vol 16 (2022)
Deriving the detailed synaptic connections of an entire nervous system is the unrealized goal of the nascent field of connectomics. For the fruit fly Drosophila, in particular, we need to dissect the brain, connectives, and ventral nerve cord as a si
Externí odkaz:
https://doaj.org/article/62695a4aa48344f0afd2803f75898979
Autor:
Temour Tokhi, Tom Dolafi, Nneoma Okeoma, Tanya Wolff, Philip M Hubbard, Kazunori Shinomiya, Madelaine K Robertson, Gerald M. Rubin, Gregory S.X.E. Jefferis, Christopher J Knecht, Laramie Leavitt, Alia Suleiman, Satoko Takemura, Christopher Ordish, Jody Clements, Ian A. Meinertzhagen, Alexander Shakeel Bates, Takashi Kawase, Samantha Finley, Nicholas Padilla, Jackie Swift, C. Shan Xu, Stuart Berg, Tyler Paterson, Ashley L Scott, Erika Neace, Shirley Lauchie, Sean M Ryan, Emily M Joyce, Shin-ya Takemura, Tim Blakely, Michael A Cook, Christopher Patrick, Bryon Eubanks, Audrey Francis, Robert Svirskas, William T. Katz, Eric T. Trautman, Caroline Mooney, Ting Zhao, Nicole A Kirk, Megan Sammons, Brandon S Canino, Reed A. George, Louis K. Scheffer, Jolanta A. Borycz, Jon Thomson Rymer, Natasha Cheatham, Dagmar Kainmueller, Gary B. Huang, Khaled Khairy, Nicole Neubarth, Elliott E Phillips, John A. Bogovic, Neha Rampally, Larry Lindsey, Viren Jain, David G. Ackerman, Jane Anne Horne, Kelli Fairbanks, Lowell Umayam, Jens Goldammer, Emily M Phillips, Donald J. Olbris, Feng Li, Emily A Manley, Philipp Schlegel, Hideo Otsuna, Marta Costa, Stephen M. Plaza, Omotara Ogundeyi, Samantha Ballinger, Charli Maldonado, Kelsey Smith, Gary Patrick Hopkins, Vivek Jayaraman, Emily Tenshaw, Julie Kovalyak, Peter H. Li, Tansy Yang, Masayoshi Ito, Miatta Ndama, Claire Smith, Michał Januszewski, Alanna Lohff, SungJin Kim, Anne K Scott, Kei Ito, Iris Talebi, Jeremy Maitlin-Shepard, Nora Forknall, Marisa Dreher, Harald F. Hess, Sari McLin, Patricia K. Rivlin, Dennis A Bailey, Kenneth J. Hayworth, Octave Duclos, Caitlin Ribeiro, John J. Walsh, Zhiyuan Lu, Dorota Tarnogorska, Ruchi Parekh, Aya Shinomiya, Stephan Saalfeld, Margaret A Sobeski, Natalie L Smith, Chelsea X Alvarado
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
The neural circuits responsible for animal behavior remain largely unknown. We summarize new methods and present the circuitry of a large fraction of the brain of the fruit fly Drosophila melanogaster. Improved methods include new procedures to prepa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27b85537abb3e13a27b3773d84eb1d0d
https://www.repository.cam.ac.uk/handle/1810/311341
https://www.repository.cam.ac.uk/handle/1810/311341
Autor:
Kenneth J, Hayworth, David, Peale, Michał, Januszewski, Graham W, Knott, Zhiyuan, Lu, C Shan, Xu, Harald F, Hess
Publikováno v:
Nature methods. 17(1)
We demonstrate gas cluster ion beam scanning electron microscopy (SEM), in which wide-area ion milling is performed on a series of thick tissue sections. This three-dimensional electron microscopy technique acquires datasets with 10 nm isotropic reso
Autor:
Eric Betzig, Igor Pisarev, Srigokul Upadhyayula, Shu-Hsien Sheu, Yongxin Zhao, Austin R. Graves, Christopher T. Zugates, Sean G. Megason, John A. Bogovic, Harald F. Hess, Adam W. Hantman, Song Pang, C. Shan Xu, Susan Tappan, Kishore R. Mosaliganti, Yoshinori Aso, Ved P. Singh, Shoh Asano, Jennifer Lippincott-Schwartz, Carolyn Ott, Gerald M. Rubin, H. Amalia Pasolli, Jennifer Colonell, Edward S. Boyden, Daniel E. Milkie, Grace H. Huynh, Tom Kirchhausen, Stephan Saalfeld, Alfredo Rodriguez, Tsung-Li Liu, Ruixuan Gao
Publikováno v:
PMC
INTRODUCTION Neural circuits across the brain are composed of structures spanning seven orders of magnitude in size that are assembled from thousands of distinct protein types. Electron microscopy has imaged densely labeled brain tissue at nanometer-
Autor:
Natasha Cheatham, Iris Talebi, Aya Shinomiya, C. Shan Xu, Claire Smith, Omotara Ogundeyi, David Peel, Kazunori Shinomiya, Shirley Lauchie, Erika Neace, Namra Ansari, Louis K. Scheffer, Roxanne Aniceto, Patricia K. Rivlin, Toufiq Parag, Zhiyuan Lu, Ian A. Meinertzhagen, Gary B. Huang, Aljoscha Nern, Christopher Ordish, Satoko Takemura, Stephen M. Plaza
Publikováno v:
eLife
eLife, Vol 8 (2019)
eLife, Vol 8 (2019)
Understanding the circuit mechanisms behind motion detection is a long-standing question in visual neuroscience. In Drosophila melanogaster, recently discovered synapse-level connectomes in the optic lobe, particularly in ON-pathway (T4) receptive-fi
Autor:
H. Amalia Pasolli, Shu-Hsien Sheu, Doreen Matthies, Song Pang, Jennifer Lippincott-Schwartz, Chi-Lun Chang, Zhe Liu, Harald F. Hess, Hui Liu, Aubrey V. Weigel, Jesse Jackson, Maria S. Ioannou, C. Shan Xu
Publikováno v:
Cell. 177(6)
Metabolic coordination between neurons and astrocytes is critical for the health of the brain. However, neuron-astrocyte coupling of lipid metabolism, particularly in response to neural activity, remains largely uncharacterized. Here, we demonstrate
Autor:
Song Pang, Frank M. J. Jacobs, Michael E. Coulter, Raphael Gaudin, C. Shan Xu, Gerrald A Lodewijk, Ganeshwaran H. Mochida, Sarah Cianférani, Harald F. Hess, Wei-Chung Allen Lee, Christopher A. Walsh, Tomas Kirchhausen, Dilenny M. Gonzalez, Monica L. Calicchio, François Delalande, Edward Yang, Cristina M. Dorobantu, Richard S. Smith, Hart G.W. Lidov, David Haussler, Eric T. Wong, Vijay S. Ganesh, Maria K. Lehtinen, Elaine T. Lim, Thorsten M. Schlaeger
Publikováno v:
Cell reports, vol 24, iss 4
Cell reports
Cell Reports, 24(4), 973-986. Cell Press
Cell Reports
Cell Reports, Elsevier Inc, 2018, 24 (4), pp.973-986.e8. ⟨10.1016/j.celrep.2018.06.100⟩
Cell reports
Cell Reports, 24(4), 973-986. Cell Press
Cell Reports
Cell Reports, Elsevier Inc, 2018, 24 (4), pp.973-986.e8. ⟨10.1016/j.celrep.2018.06.100⟩
SUMMARY Endosomal sorting complex required for transport (ESCRT) complex proteins regulate biogenesis and release of extracellular vesicles (EVs), which enable cell-to-cell communication in the nervous system essential for development and adult funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47d13408544f44c62adec62a2110dd84
Autor:
C Shan Xu, Kenneth J Hayworth, Zhiyuan Lu, Patricia Grob, Ahmed M Hassan, José G García-Cerdán, Krishna K Niyogi, Eva Nogales, Richard J Weinberg, Harald F Hess
Publikováno v:
Xu, CS; Hayworth, KJ; Lu, Z; Grob, P; Hassan, AM; García-Cerdán, JG; et al.(2017). Enhanced FIB-SEM systems for large-volume 3D imaging. eLife, 6. doi: 10.7554/eLife.25916. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/3sr9c8s2
eLife
eLife, Vol 6 (2017)
eLife
eLife, Vol 6 (2017)
Focused Ion Beam Scanning Electron Microscopy (FIB-SEM) can automatically generate 3D images with superior z-axis resolution, yielding data that needs minimal image registration and related post-processing. Obstacles blocking wider adoption of FIB-SE
Autor:
Pietro De Camilli, C. Shan Xu, Harald F. Hess, Yumei Wu, Christina Whiteus, Kenneth J. Hayworth, Richard J. Weinberg
Close appositions between the membrane of the endoplasmic reticulum (ER) and other intracellular membranes have important functions in cell physiology. These include lipid homeostasis, regulation of Ca2+ dynamics, and control of organelle biogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b3b54a1a702fdac7986ec38c0d46752
Autor:
Juan Carlos Tapia, Jeff W. Lichtman, Graham Knott, Zhiyuan Lu, Kenneth J. Hayworth, Richard D. Fetter, C. Shan Xu, Harald F. Hess
Publikováno v:
Nature methods
Focused-ion-beam scanning electron microscopy (FIB-SEM) has become an essential tool for studying neural tissue at resolutions below 10 nm x 10 nm x 10 nm, producing data sets optimized for automatic connectome tracing. We present a technical advance