Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Morris, AD"'
Autor:
Keaton JM; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.; Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Kamali Z; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.; Department of Bioinformatics, Isfahan University of Medical Sciences, Isfahan, Iran., Xie T; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Vaez A; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands. a.vaez@umcg.nl.; Department of Bioinformatics, Isfahan University of Medical Sciences, Isfahan, Iran. a.vaez@umcg.nl., Williams A; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Goleva SB; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Ani A; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.; Department of Bioinformatics, Isfahan University of Medical Sciences, Isfahan, Iran., Evangelou E; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece.; Department of Biomedical Research, Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology-Hellas, Ioannina, Greece., Hellwege JN; Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.; Biomedical Laboratory Research and Development, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA., Yengo L; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Young WJ; Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Barts Heart Centre, St Bartholomew's Hospital, Barts Health NHS Trust, London, UK., Traylor M; Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Department of Genetics, Novo Nordisk Research Centre Oxford, Oxford, UK., Giri A; Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; Division of Quantitative Sciences, Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Nashville, TN, USA., Zheng Z; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia.; Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA., Zeng J; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Chasman DI; Division of Preventive Medicine Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Morris AP; Centre for Genetics and Genomics Versus Arthritis, Centre for Musculoskeletal Research, The University of Manchester, Manchester, UK., Caulfield MJ; Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; NIHR Barts Cardiovascular Biomedical Research Centre, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Hwang SJ; Population Sciences Branch, NHLBI Framingham Heart Study, Framingham, MA, USA.; Department of Biostatistics, Boston University, Boston, MA, USA., Kooner JS; National Heart and Lung Institute, Imperial College London, London, UK., Conen D; Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada., Attia JR; Faculty of Health and Medicine, University of Newcastle, New Lambton Heights, Newcastle, New South Wales, Australia., Morrison AC; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Loos RJF; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Kristiansson K; Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland., Schmidt R; Department of Neurology/Medical University Graz, Graz, Austria., Hicks AA; Institute for Biomedicine, Eurac Research, Bolzano, Italy.; University of Lübeck, Lübeck, Germany., Pramstaller PP; Institute for Biomedicine, Eurac Research, Bolzano, Italy.; University of Lübeck, Lübeck, Germany., Nelson CP; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Leicester, UK., Samani NJ; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Leicester, UK., Risch L; Faculty of Medical Sciences, Private University of the Principality of Liechtenstein, Triesen, Liechtenstein.; Department of Laboratory Medicine, Dr. Risch Anstalt, Vaduz, Liechtenstein., Gyllensten U; Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden., Melander O; Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden.; Department of Internal Medicine, Skåne University Hospital, Malmö, Sweden., Riese H; Interdisciplinary Center Psychopathology and Emotional Regulation (ICPE), Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Wilson JF; Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, Scotland.; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, Scotland., Campbell H; Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, Scotland., Rich SS; Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA., Psaty BM; Cardiovascular Health Research Unit, Departments of Medicine, Epidemiology, and Health Systems and Population Health, University of Washington, Seattle, WA, USA., Lu Y; Vanderbilt Genetic Institute, Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Rotter JI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Guo X; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Rice KM; Department of Biostatistics, University of Washington, Seattle, WA, USA., Vollenweider P; Department of Medicine, Internal Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Sundström J; Department of Medical Sciences, Uppsala University, Uppsala, Sweden.; The George Institute for Global Health, University of New South Wales, Sydney, New South Wales, Australia., Langenberg C; MRC Epidemiology Unit, University of Cambridge, Cambridge, UK.; Computational Medicine, Berlin Institute of Health (BIH) at Charité - Universitätsmedizin Berlin, Berlin, Germany.; Precision Healthcare University Research Institute, Queen Mary University of London, London, UK., Tobin MD; Department of Health Sciences, University of Leicester, Leicester, UK.; Leicester NIHR Respiratory Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Giedraitis V; Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden., Luan J; MRC Epidemiology Unit, University of Cambridge, Cambridge, UK., Tuomilehto J; Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland.; Department of Public Health, University of Helsinki, Helsinki, Finland.; Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia., Kutalik Z; Center for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Ripatti S; Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki, Finland.; Department of Public Health, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Salomaa V; Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland., Girotto G; Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy.; Institute for Maternal and Child Health - IRCCS, Burlo Garofolo, Trieste, Italy., Trompet S; Department Internal Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands.; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands., Jukema JW; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.; Netherlands Heart Institute, Utrecht, the Netherlands., van der Harst P; Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands.; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Ridker PM; Division of Preventive Medicine Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Giulianini F; Division of Preventive Medicine Brigham and Women's Hospital, Boston, MA, USA., Vitart V; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, Scotland., Goel A; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.; Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Watkins H; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.; Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Harris SE; Lothian Birth Cohorts Group, Department of Psychology, The University of Edinburgh, Edinburgh, UK., Deary IJ; Lothian Birth Cohorts Group, Department of Psychology, The University of Edinburgh, Edinburgh, UK., van der Most PJ; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Oldehinkel AJ; Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Keavney BD; Division of Cardiovascular Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.; Manchester Heart Institute, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK., Hayward C; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, Scotland.; Centre for Genomic and Experimental Medicine, IGC, University of Edinburgh, Edinburgh, UK., Campbell A; Centre for Genomic and Experimental Medicine, IGC, University of Edinburgh, Edinburgh, UK.; Usher Institute, University of Edinburgh, Edinburgh, UK., Boehnke M; Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Scott LJ; Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Boutin T; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, Scotland., Mamasoula C; Population Health Sciences Institute, Newcastle University, Newcastle, UK., Järvelin MR; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland.; Unit of Primary Health Care, Oulu University Hospital, OYS, Oulu, Finland., Peters A; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Lehrstuhl für Epidemiologie, Institut für Medizinische Informationsverarbeitung, Biometrie und Epidemiologie (IBE), Ludwig-Maximilians-Universität München, Neuherberg, Germany., Gieger C; Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Lakatta EG; Laboratory of Cardiovascular Science, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA., Cucca F; Institute of Genetic and Biomedical Research, National Research Council (CNR), Monserrato, Italy., Hui J; Busselton Population Medical Research Institute, Perth, Western Australia, Australia.; School of Population and Global Health, The University of Western Australia, Nedlands, Western Australia, Australia., Knekt P; Population Health Unit, Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland., Enroth S; Department of Immunology, Genetics, and Pathology, Biomedical Center, Science for Life Laboratory (SciLifeLab) Uppsala, Uppsala University, Uppsala, Sweden., De Borst MH; Department of Medicine, Division of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Polašek O; University of Split School of Medicine, Split, Croatia.; Algebra University College, Zagreb, Croatia., Concas MP; Institute for Maternal and Child Health - IRCCS, Burlo Garofolo, Trieste, Italy., Catamo E; Institute for Maternal and Child Health - IRCCS, Burlo Garofolo, Trieste, Italy., Cocca M; Institute for Maternal and Child Health - IRCCS, Burlo Garofolo, Trieste, Italy., Li-Gao R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Hofer E; Clinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz, Graz, Austria.; Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz, Graz, Austria., Schmidt H; Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Medical University of Graz, Graz, Austria., Spedicati B; Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy., Waldenberger M; Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany., Strachan DP; Population Health Sciences Institute St George's, University of London, London, UK., Laan M; Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia., Teumer A; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany., Dörr M; DZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany.; Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany., Gudnason V; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Kopavogur, Iceland., Cook JP; Department of Health Data Science, University of Liverpool, Liverpool, UK., Ruggiero D; IRCCS Neuromed, Pozzilli, Italy.; Institute of Genetics and Biophysics - 'A. Buzzati-Traverso', National Research Council of Italy, Naples, Italy., Kolcic I; Algebra University College, Zagreb, Croatia.; Department of Public Health, University of Split School of Medicine, Split, Croatia., Boerwinkle E; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA., Traglia M; Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milan, Italy., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Raitakari OT; Centre for Population Health Research, University of Turku and Turku University Hospital, Turku, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland., Johnson AD; Population Sciences Branch, NHLBI Framingham Heart Study, Framingham, MA, USA.; The Framingham Heart Study, Framingham, MA, USA., Newton-Cheh C; Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Cardiovascular Research Center and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA., Brown MJ; Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Dominiczak AF; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK., Sever PJ; International Centre for Circulatory Health, Imperial College London, London, UK., Poulter N; School of Public Health, Imperial College London, London, UK., Chambers JC; Lee Kong Chian School of Medicine, Nanyang Technological University Singapore, Singapore, Singapore., Elosua R; Hospital del Mar Research Institute (IMIM), Barcelona, Spain.; CIBER Enfermedades Cardiovasculares (CIBERCV), Barcelona, Spain.; Faculty of Medicine, University of Vic-Central University of Catalonia (UVic-UCC), Vic, Spain., Siscovick D; New York Academy of Medicine, New York, NY, USA., Esko T; Institute of Genomics, University of Tartu, Tartu, Estonia., Metspalu A; Institute of Genomics, University of Tartu, Tartu, Estonia., Strawbridge RJ; Institute of Health and Wellbeing, University of Glasgow, Glasgow, UK.; Health Data Research UK, Glasgow, UK.; Division of Cardiovascular Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden., Laakso M; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, Finland.; Kuopio University Hospital, Kuopio, Finland., Hamsten A; Division of Cardiovascular Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden., Hottenga JJ; Department of Biological Psychology, Faculty of Behavioural and Movement Sciences, Vrije Universiteit, Amsterdam, the Netherlands., de Geus E; Department of Biological Psychology, Faculty of Behavioural and Movement Sciences, Vrije Universiteit, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, Amsterdam University Medical Centre, Amsterdam, the Netherlands., Morris AD; Data Science, University of Edinburgh, Edinburgh, UK.; Health Data Research UK, London, UK., Palmer CNA; Population Health and Genomics, School of Medicine, University of Dundee, Dundee, UK., Nolte IM; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Milaneschi Y; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Psychiatry, Amsterdam Public Health Research Institute, Amsterdam, the Netherlands., Marten J; Centre for Genomic and Experimental Medicine, IGC, University of Edinburgh, Edinburgh, UK., Wright A; Centre for Genomic and Experimental Medicine, IGC, University of Edinburgh, Edinburgh, UK., Zeggini E; Institute of Translational Genomics, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.; Technical University of Munich (TUM) and Klinikum Rechts der Isar, TUM School of Medicine, Munich, Germany., Howson JMM; Department of Genetics, Novo Nordisk Research Centre Oxford, Oxford, UK.; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., O'Donnell CJ; VA Boston Healthcare System, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Spector T; Department of Twin Research, King's College London, London, UK., Nalls MA; Center for Alzheimer's and Related Dementias, NIA/NINDS, NIH, Bethesda, MD, USA.; Laboratory of Neurogenetics, NIA, NIH, Bethesda, MD, USA.; DataTecnica LLC, Washington, DC, USA., Simonsick EM; Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA., Liu Y; Division of Cardiology, Duke University School of Medicine, Durham, NC, USA., van Duijn CM; Nuffield Department of Population Health, Big Data Institute, University of Oxford, Oxford, UK., Butterworth AS; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK.; Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge, UK.; National Institute for Health and Care Research Blood and Transplant Research Unit in Donor Health and Behaviour, University of Cambridge, Cambridge, UK., Danesh JN; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK.; Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge, UK.; National Institute for Health and Care Research Blood and Transplant Research Unit in Donor Health and Behaviour, University of Cambridge, Cambridge, UK.; Department of Human Genetics, The Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Menni C; Department of Twin Research and Genetic Epidemiology, London, UK., Wareham NJ; MRC Epidemiology Unit, University of Cambridge, Cambridge, UK., Khaw KT; Department of Public Health and Primary Care, University of Cambridge School of Clinical Medicine, Cambridge, UK., Sun YV; Department of Epidemiology, Emory University Rollins School of Public Health, Atlanta, Georgia, USA.; VA Atlanta Healthcare System, Decatur, GA, USA., Wilson PWF; Emory Clinical Cardiovascular Research Institute, Atlanta, GA, USA.; Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), VA Boston Healthcare System, Boston, MA, USA., Cho K; Division of Aging, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Cardiovascular Health Research Unit, Departments of Medicine and Epidemiology, University of Washington, Seattle, WA, USA., Visscher PM; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Denny JC; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Levy D; Population Sciences Branch, NHLBI Framingham Heart Study, Framingham, MA, USA.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland., Edwards TL; Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA. todd.l.edwards@vumc.org., Munroe PB; Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; NIHR Barts Cardiovascular Biomedical Research Centre, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Warren HR; Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK. h.r.warren@qmul.ac.uk.; NIHR Barts Cardiovascular Biomedical Research Centre, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK. h.r.warren@qmul.ac.uk.
Publikováno v:
Nature genetics [Nat Genet] 2024 May; Vol. 56 (5), pp. 778-791. Date of Electronic Publication: 2024 Apr 30.
Autor:
Evangelou E; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece., Warren HR; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; National Institute for Health Research, Barts Cardiovascular Biomedical Research Center, Queen Mary University of London, London, UK., Mosen-Ansorena D; Department of Epidemiology and Biostatistics, Imperial College London, London, UK., Mifsud B; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Pazoki R; Department of Epidemiology and Biostatistics, Imperial College London, London, UK., Gao H; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; MRC-PHE Centre for Environment and Health, Imperial College London, London, UK., Ntritsos G; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece., Dimou N; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece., Cabrera CP; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; National Institute for Health Research, Barts Cardiovascular Biomedical Research Center, Queen Mary University of London, London, UK., Karaman I; Department of Epidemiology and Biostatistics, Imperial College London, London, UK., Ng FL; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Evangelou M; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Department of Mathematics, Imperial College London, London, UK., Witkowska K; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Tzanis E; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Hellwege JN; Division of Epidemiology, Department of Medicine, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA., Giri A; Vanderbilt Genetics Institute, Vanderbilt Epidemiology Center, Department of Obstetrics and Gynecology, Vanderbilt University Medical Center; Tennessee Valley Health Systems VA, Nashville, TN, USA., Velez Edwards DR; Vanderbilt Genetics Institute, Vanderbilt Epidemiology Center, Department of Obstetrics and Gynecology, Vanderbilt University Medical Center; Tennessee Valley Health Systems VA, Nashville, TN, USA., Sun YV; Department of Epidemiology, Emory University Rollins School of Public Health, Atlanta, GA, USA.; Department of Biomedical Informatics, Emory University School of Medicine, Atlanta, GA, USA., Cho K; Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), VA Boston Healthcare System, Boston, MA, USA.; Division of Aging, Department of Medicine, Brigham and Women's Hospital; Department of Medicine, Harvard Medical School, Boston, MA, USA., Gaziano JM; Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), VA Boston Healthcare System, Boston, MA, USA.; Division of Aging, Department of Medicine, Brigham and Women's Hospital; Department of Medicine, Harvard Medical School, Boston, MA, USA., Wilson PWF; Atlanta VAMC and Emory Clinical Cardiovascular Research Institute, Atlanta, GA, USA., Tsao PS; VA Palo Alto Health Care System, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, USA., Kovesdy CP; Nephrology Section, Memphis VA Medical Center and University of Tennessee Health Science Center, Memphis, TN, USA., Esko T; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA., Mägi R; Estonian Genome Center, University of Tartu, Tartu, Estonia., Milani L; Estonian Genome Center, University of Tartu, Tartu, Estonia., Almgren P; Department Clinical Sciences, Malmö, Lund University, Malmö, Sweden., Boutin T; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, UK., Debette S; Department of Neurology, Bordeaux University Hospital, Bordeaux, France.; Univ. Bordeaux, Inserm, Bordeaux Population Health Research Center, CHU Bordeaux, Bordeaux, France., Ding J; Laboratory of Genetics and Genomics, NIA/NIH, Baltimore, MD, USA., Giulianini F; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA., Holliday EG; Hunter Medical Research Institute and Faculty of Health, University of Newcastle, New Lambton Heights, New South Wales, Australia., Jackson AU; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Li-Gao R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Lin WY; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Luan J; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Mangino M; Department of Twin Research and Genetic Epidemiology, Kings College London, London, UK.; NIHR Biomedical Research Centre at Guy's and St Thomas' Foundation Trust, London, UK., Oldmeadow C; Hunter Medical Research Institute and Faculty of Health, University of Newcastle, New Lambton Heights, New South Wales, Australia., Prins BP; Wellcome Trust Sanger Institute, Hinxton, UK., Qian Y; Laboratory of Genetics and Genomics, NIA/NIH, Baltimore, MD, USA., Sargurupremraj M; Univ. Bordeaux, Inserm, Bordeaux Population Health Research Center, CHU Bordeaux, Bordeaux, France., Shah N; Division of Molecular and Clinical Medicine, School of Medicine, University of Dundee, Dundee, UK.; Department of Pharmacy, COMSATS Institute of Information Technology, Abbottabad, Pakistan., Surendran P; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Thériault S; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.; Institut universitaire de cardiologie et de pneumologie de Québec-Université Laval, Quebec City, Quebec, Canada., Verweij N; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Cardiovascular Research Center and Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA, USA.; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, the Netherlands., Willems SM; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Zhao JH; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Amouyel P; University of Lille, Inserm, Centre Hosp. Univ. Lille, Institut Pasteur de Lille, UMR1167 - RID-AGE - Risk factors and molecular determinants of aging-related diseases, Epidemiology and Public Health Department, Lille, France., Connell J; University of Dundee, Ninewells Hospital & Medical School, Dundee, UK., de Mutsert R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Doney ASF; Division of Molecular and Clinical Medicine, School of Medicine, University of Dundee, Dundee, UK., Farrall M; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Menni C; Department of Twin Research and Genetic Epidemiology, Kings College London, London, UK., Morris AD; Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Noordam R; Department of Internal Medicine, Section Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands., Paré G; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada., Poulter NR; Imperial Clinical Trials Unit, London, UK., Shields DC; School of Medicine, University College Dublin, Dublin, Ireland., Stanton A; Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland., Thom S; International Centre for Circulatory Health, Imperial College London, London, UK., Abecasis G; Center for Statistical Genetics, Department of Biostatistics, SPH II, Washington Heights, Ann Arbor, MI, USA., Amin N; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands., Arking DE; Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Ayers KL; Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK.; Sema4, a Mount Sinai venture, Stamford, CT, USA., Barbieri CM; Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milan, Italy., Batini C; Department of Health Sciences, University of Leicester, Leicester, UK., Bis JC; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA., Blake T; Department of Health Sciences, University of Leicester, Leicester, UK., Bochud M; Institute of Social and Preventive Medicine, University Hospital of Lausanne, Lausanne, Switzerland., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Boerwinkle E; Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston and Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA., Boomsma DI; Department of Biological Psychology, Vrije Universiteit Amsterdam, EMGO+ Institute, VU University Medical Center, Amsterdam, the Netherlands., Bottinger EP; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Braund PS; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Brumat M; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy., Campbell A; Medical Genetics Section, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.; Generation Scotland, Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, UK., Campbell H; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland, UK., Chakravarti A; Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Chambers JC; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; MRC-PHE Centre for Environment and Health, Imperial College London, London, UK.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; Department of Cardiology, Ealing Hospital, Middlesex, UK.; Imperial College Healthcare NHS Trust, London, UK., Chauhan G; Centre for Brain Research, Indian Institute of Science, Bangalore, India., Ciullo M; Institute of Genetics and Biophysics 'A. Buzzati-Traverso', CNR, Napoli, Italy.; IRCCS Neuromed, Pozzilli, Isernia, Italy., Cocca M; Institute for Maternal and Child Health IRCCS Burlo Garofolo, Trieste, Italy., Collins F; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, MD, USA., Cordell HJ; Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK., Davies G; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., de Borst MH; Department of Internal Medicine, Division of Nephrology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., de Geus EJ; Department of Biological Psychology, Vrije Universiteit Amsterdam, EMGO+ Institute, VU University Medical Center, Amsterdam, the Netherlands., Deary IJ; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., Deelen J; Department of Molecular Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Del Greco M F; Institute for Biomedicine, Eurac Research, Bolzano, Italy - Affiliated Institute of the University of Lübeck, Lübeck, Germany., Demirkale CY; Mathematical and Statistical Computing Laboratory, Office of Intramural Research, Center for Information Technology, National Institutes of Health, Bethesda, MD, USA., Dörr M; Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany., Ehret GB; Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Cardiology, Department of Medicine, Geneva University Hospital, Geneva, Switzerland., Elosua R; CIBERCV & Cardiovascular Epidemiology and Genetics, IMIM, Barcelona, Spain.; Faculty of Medicine, Universitat de Vic-Central de Catalunya, Vic, Spain., Enroth S; Department of Immunology, Genetics and Pathology, Uppsala Universitet, Science for Life Laboratory, Uppsala, Sweden., Erzurumluoglu AM; Department of Health Sciences, University of Leicester, Leicester, UK., Ferreira T; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.; Big Data Institute, Li Ka Shing Center for Health for Health Information and Discovery, Oxford University, Oxford, UK., Frånberg M; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.; Centre for Molecular Medicine, L8:03, Karolinska Universitetsjukhuset, Solna, Sweden.; Department of Numerical Analysis and Computer Science, Stockholm University, Stockholm, Sweden., Franco OH; Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands., Gandin I; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy., Gasparini P; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.; Institute for Maternal and Child Health IRCCS Burlo Garofolo, Trieste, Italy., Giedraitis V; Department of Public Health and Caring Sciences, Geriatrics, Uppsala, Sweden., Gieger C; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany., Girotto G; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.; Institute for Maternal and Child Health IRCCS Burlo Garofolo, Trieste, Italy., Goel A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Gow AJ; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, School of Social Sciences, Heriot-Watt University, Edinburgh, UK., Gudnason V; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; Icelandic Heart Association, Kopavogur, Iceland., Guo X; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Gyllensten U; Department of Immunology, Genetics and Pathology, Uppsala Universitet, Science for Life Laboratory, Uppsala, Sweden., Hamsten A; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.; Centre for Molecular Medicine, L8:03, Karolinska Universitetsjukhuset, Solna, Sweden., Harris TB; Intramural Research Program, Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, MD, USA., Harris SE; Medical Genetics Section, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK., Hartman CA; Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Havulinna AS; Department of Public Health Solutions, National Institute for Health and Welfare (THL), Helsinki, Finland.; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland., Hicks AA; Institute for Biomedicine, Eurac Research, Bolzano, Italy - Affiliated Institute of the University of Lübeck, Lübeck, Germany., Hofer E; Clinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz, Graz, Austria.; Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz, Graz, Austria., Hofman A; Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Hottenga JJ; Department of Biological Psychology, Vrije Universiteit Amsterdam, EMGO+ Institute, VU University Medical Center, Amsterdam, the Netherlands., Huffman JE; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, UK.; National Heart, Lung and Blood Institute's Framingham Heart Study, Framingham, MA, USA.; The Population Science Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA., Hwang SJ; National Heart, Lung and Blood Institute's Framingham Heart Study, Framingham, MA, USA.; The Population Science Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA., Ingelsson E; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.; Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA., James A; Department of Pulmonary Physiology and Sleep, Sir Charles Gairdner Hospital, Hospital Avenue, Nedlands, Western Australia, Australia.; School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia, Australia., Jansen R; Department of Psychiatry, VU University Medical Center, Amsterdam Neuroscience, Amsterdam, the Netherlands., Jarvelin MR; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; MRC-PHE Centre for Environment and Health, Imperial College London, London, UK.; Biocenter Oulu, University of Oulu, Oulu, Finland.; Center For Life-course Health Research, University of Oulu, Oulu, Finland.; Unit of Primary Care, Oulu University Hospital, Oulu, Oulu, Finland., Joehanes R; National Heart, Lung and Blood Institute's Framingham Heart Study, Framingham, MA, USA.; Hebrew SeniorLife, Harvard Medical School, Boston, MA, USA., Johansson Å; Department of Immunology, Genetics and Pathology, Uppsala Universitet, Science for Life Laboratory, Uppsala, Sweden., Johnson AD; National Heart, Lung and Blood Institute's Framingham Heart Study, Framingham, MA, USA.; Population Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA., Joshi PK; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland, UK., Jousilahti P; Department of Public Health Solutions, National Institute for Health and Welfare (THL), Helsinki, Finland., Jukema JW; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands., Jula A; Department of Public Health Solutions, National Institute for Health and Welfare (THL), Helsinki, Finland., Kähönen M; Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland.; Department of Clinical Physiology, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland., Kathiresan S; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Cardiovascular Research Center and Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA, USA.; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA., Keavney BD; Division of Cardiovascular Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.; Division of Medicine, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK., Khaw KT; Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge, Cambridge, UK., Knekt P; Department of Public Health Solutions, National Institute for Health and Welfare (THL), Helsinki, Finland., Knight J; Data Science Institute and Lancaster Medical School, Lancaster, UK., Kolcic I; Department of Public Health, Faculty of Medicine, University of Split, Split, Croatia., Kooner JS; MRC-PHE Centre for Environment and Health, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital, Middlesex, UK.; Imperial College Healthcare NHS Trust, London, UK.; National Heart and Lung Institute, Imperial College London, London, UK., Koskinen S; Department of Public Health Solutions, National Institute for Health and Welfare (THL), Helsinki, Finland., Kristiansson K; Department of Public Health Solutions, National Institute for Health and Welfare (THL), Helsinki, Finland., Kutalik Z; Institute of Social and Preventive Medicine, University Hospital of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Laan M; Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia., Larson M; National Heart, Lung and Blood Institute's Framingham Heart Study, Framingham, MA, USA., Launer LJ; Intramural Research Program, Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, MD, USA., Lehne B; Department of Epidemiology and Biostatistics, Imperial College London, London, UK., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland., Liewald DCM; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., Lin L; Cardiology, Department of Medicine, Geneva University Hospital, Geneva, Switzerland., Lind L; Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala, Sweden., Lindgren CM; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Big Data Institute, Li Ka Shing Center for Health for Health Information and Discovery, Oxford University, Oxford, UK.; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA., Liu Y; Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, USA., Loos RJF; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK.; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Mindich Child Health Development Institute, The Icahn School of Medicine at Mount Sinai, New York, NY, USA., Lopez LM; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychiatry, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin, Ireland.; University College Dublin, UCD Conway Institute, Centre for Proteome Research, UCD, Belfield, Dublin, Ireland., Lu Y; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland., Mahajan A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Mamasoula C; Institute of Health and Society, Newcastle University, Newcastle upon Tyne, UK., Marrugat J; CIBERCV & Cardiovascular Epidemiology and Genetics, IMIM, Barcelona, Spain., Marten J; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, UK., Milaneschi Y; Department of Psychiatry, Amsterdam Public Health and Amsterdam Neuroscience, VU University Medical Center/GGZ inGeest, Amsterdam, the Netherlands., Morgan A; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy., Morris AP; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Department of Biostatistics, University of Liverpool, Liverpool, UK., Morrison AC; Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA., Munson PJ; Mathematical and Statistical Computing Laboratory, Office of Intramural Research, Center for Information Technology, National Institutes of Health, Bethesda, MD, USA., Nalls MA; Data Tecnica International, Glen Echo, MD, USA.; Laboratory of Neurogenetics, National Institute on Aging, Bethesda, MD, USA., Nandakumar P; Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Nelson CP; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Niiranen T; Department of Public Health Solutions, National Institute for Health and Welfare (THL), Helsinki, Finland.; Department of Medicine, Turku University Hospital and University of Turku, Turku, Finland., Nolte IM; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Nutile T; Institute of Genetics and Biophysics 'A. Buzzati-Traverso', CNR, Napoli, Italy., Oldehinkel AJ; Interdisciplinary Center Psychopathology and Emotion Regulation (ICPE), University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Oostra BA; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands., O'Reilly PF; SGDP Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Org E; Estonian Genome Center, University of Tartu, Tartu, Estonia., Padmanabhan S; Generation Scotland, Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, UK.; British Heart Foundation Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK., Palmas W; Department of Medicine, Columbia University Medical Center, New York, NY, USA., Palotie A; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; Analytic and Translational Genetics Unit, Department of Medicine, Department of Neurology and Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.; The Stanley Center for Psychiatric Research and Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Pattie A; Department of Psychology, University of Edinburgh, Edinburgh, UK., Penninx BWJH; Department of Psychiatry, Amsterdam Public Health and Amsterdam Neuroscience, VU University Medical Center/GGZ inGeest, Amsterdam, the Netherlands., Perola M; Department of Public Health Solutions, National Institute for Health and Welfare (THL), Helsinki, Finland.; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; University of Tartu, Tartu, Estonia., Peters A; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany.; German Center for Cardiovascular Disease Research (DZHK), partner site Munich, Neuherberg, Germany., Polasek O; Department of Public Health, Faculty of Medicine, University of Split, Split, Croatia.; Psychiatric Hospital 'Sveti Ivan', Zagreb, Croatia., Pramstaller PP; Institute for Biomedicine, Eurac Research, Bolzano, Italy - Affiliated Institute of the University of Lübeck, Lübeck, Germany.; Department of Neurology, General Central Hospital, Bolzano, Italy.; Department of Neurology, University of Lübeck, Lübeck, Germany., Nguyen QT; Mathematical and Statistical Computing Laboratory, Office of Intramural Research, Center for Information Technology, National Institutes of Health, Bethesda, MD, USA., Raitakari OT; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland., Ren M; Fujian Key Laboratory of Geriatrics, Department of Geriatric Medicine, Fujian Provincial Hospital, Fujian Medical University, Fuzhou, China., Rettig R; Institute of Physiology, University Medicine Greifswald, Karlsburg, Germany., Rice K; Department of Biostatistics, University of Washington, Seattle, WA, USA., Ridker PM; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Ried JS; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Riese H; Interdisciplinary Center Psychopathology and Emotion Regulation (ICPE), University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Ripatti S; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; Public Health, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Robino A; Institute for Maternal and Child Health IRCCS Burlo Garofolo, Trieste, Italy., Rose LM; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA., Rotter JI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Rudan I; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland, UK., Ruggiero D; Institute of Genetics and Biophysics 'A. Buzzati-Traverso', CNR, Napoli, Italy.; IRCCS Neuromed, Pozzilli, Isernia, Italy., Saba Y; Gottfried Schatz Research Center for Cell Signaling, Metabolism & Aging, Molecular Biology and Biochemistry, Medical University of Graz, Graz, Austria., Sala CF; Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milan, Italy., Salomaa V; Department of Public Health Solutions, National Institute for Health and Welfare (THL), Helsinki, Finland., Samani NJ; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Sarin AP; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland., Schmidt R; Clinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz, Graz, Austria., Schmidt H; Gottfried Schatz Research Center for Cell Signaling, Metabolism & Aging, Molecular Biology and Biochemistry, Medical University of Graz, Graz, Austria., Shrine N; Department of Health Sciences, University of Leicester, Leicester, UK., Siscovick D; The New York Academy of Medicine, New York, NY, USA., Smith AV; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; Icelandic Heart Association, Kopavogur, Iceland., Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Sõber S; Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia., Sorice R; Institute of Genetics and Biophysics 'A. Buzzati-Traverso', CNR, Napoli, Italy., Starr JM; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Alzheimer Scotland Dementia Research Centre, University of Edinburgh, Edinburgh, UK., Stott DJ; Institute of Cardiovascular and Medical Sciences, Faculty of Medicine, University of Glasgow, Glasgow, UK., Strachan DP; Population Health Research Institute, St George's, University of London, London, UK., Strawbridge RJ; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.; Centre for Molecular Medicine, L8:03, Karolinska Universitetsjukhuset, Solna, Sweden., Sundström J; Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala, Sweden., Swertz MA; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Taylor KD; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Teumer A; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany., Tobin MD; Department of Health Sciences, University of Leicester, Leicester, UK., Tomaszewski M; Division of Cardiovascular Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.; Division of Medicine, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK., Toniolo D; Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milan, Italy., Traglia M; Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milan, Italy., Trompet S; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands., Tuomilehto J; Dasman Diabetes Institute, Dasman, Kuwait.; Chronic Disease Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland.; Department of Public Health, University of Helsinki, Helsinki, Finland.; Saudi Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia., Tzourio C; Univ. Bordeaux, Inserm, Bordeaux Population Health Research Center, CHU Bordeaux, Bordeaux, France., Uitterlinden AG; Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands.; Department of Internal Medicine, Erasmus MC, Rotterdam, the Netherlands., Vaez A; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.; Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran., van der Most PJ; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., van Duijn CM; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands., Vergnaud AC; Department of Epidemiology and Biostatistics, Imperial College London, London, UK., Verwoert GC; Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands., Vitart V; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, UK., Völker U; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Vollenweider P; Department of Internal Medicine, University Hospital, CHUV, Lausanne, Switzerland., Vuckovic D; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.; Experimental Genetics Division, Sidra Medical and Research Center, Doha, Qatar., Watkins H; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Wild SH; Centre for Population Health Sciences, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland, UK., Willemsen G; Department of Biological Psychology, Vrije Universiteit Amsterdam, EMGO+ Institute, VU University Medical Center, Amsterdam, the Netherlands., Wilson JF; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, UK.; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland, UK., Wright AF; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, UK., Yao J; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Zemunik T; Department of Biology, Faculty of Medicine, University of Split, Split, Croatia., Zhang W; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital, Middlesex, UK., Attia JR; Hunter Medical Research Institute and Faculty of Health, University of Newcastle, New Lambton Heights, New South Wales, Australia., Butterworth AS; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; The National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, UK., Chasman DI; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Conen D; Division of Cardiology, University Hospital, Basel, Switzerland.; Division of Cardiology, Department of Medicine, McMaster University, Hamilton, Ontario, Canada., Cucca F; Institute of Genetic and Biomedical Research, National Research Council (CNR), Monserrato, Cagliari, Italy.; Department of Biomedical Sciences, University of Sassari, Sassari, Italy., Danesh J; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; The National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, UK., Hayward C; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, UK., Howson JMM; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Laakso M; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Lakatta EG; Laboratory of Cardiovascular Science, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA., Langenberg C; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Melander O; Department Clinical Sciences, Malmö, Lund University, Malmö, Sweden., Mook-Kanamori DO; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.; Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, the Netherlands., Palmer CNA; Division of Molecular and Clinical Medicine, School of Medicine, University of Dundee, Dundee, UK., Risch L; Labormedizinisches Zentrum Dr. Risch, Schaan, Liechtenstein.; Private University of the Principality of Liechtenstein, Triesen, Liechtenstein.; University Institute of Clinical Chemistry, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Scott RA; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Scott RJ; Hunter Medical Research Institute and Faculty of Health, University of Newcastle, New Lambton Heights, New South Wales, Australia., Sever P; National Heart and Lung Institute, Imperial College London, London, UK., Spector TD; Department of Twin Research and Genetic Epidemiology, Kings College London, London, UK., van der Harst P; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Wareham NJ; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK., Zeggini E; Wellcome Trust Sanger Institute, Hinxton, UK., Levy D; National Heart, Lung and Blood Institute's Framingham Heart Study, Framingham, MA, USA.; Population Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA., Munroe PB; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; National Institute for Health Research, Barts Cardiovascular Biomedical Research Center, Queen Mary University of London, London, UK., Newton-Cheh C; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA., Brown MJ; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; National Institute for Health Research, Barts Cardiovascular Biomedical Research Center, Queen Mary University of London, London, UK., Metspalu A; Estonian Genome Center, University of Tartu, Tartu, Estonia., Hung AM; Tennessee Valley Healthcare System (Nashville VA) & Vanderbilt University, Nashville, TN, USA., O'Donnell CJ; VA Boston Healthcare, Section of Cardiology and Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Edwards TL; Division of Epidemiology, Department of Medicine, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Tennessee Valley Healthcare System (626)/Vanderbilt University, Nashville, TN, USA., Psaty BM; Cardiovascular Health Research Unit, Departments of Medicine, Epidemiology and Health Services, University of Washington, Seattle, WA, USA.; Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA., Tzoulaki I; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece.; MRC-PHE Centre for Environment and Health, Imperial College London, London, UK., Barnes MR; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; National Institute for Health Research, Barts Cardiovascular Biomedical Research Center, Queen Mary University of London, London, UK., Wain LV; Department of Health Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK., Elliott P; Department of Epidemiology and Biostatistics, Imperial College London, London, UK. p.elliott@imperial.ac.uk.; MRC-PHE Centre for Environment and Health, Imperial College London, London, UK. p.elliott@imperial.ac.uk.; National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare NHS Trust and Imperial College London, London, UK. p.elliott@imperial.ac.uk.; UK Dementia Research Institute (UK DRI) at Imperial College London, London, UK. p.elliott@imperial.ac.uk.; Health Data Research-UK London substantive site, London, UK. p.elliott@imperial.ac.uk., Caulfield MJ; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK. m.j.caulfield@qmul.ac.uk.; National Institute for Health Research, Barts Cardiovascular Biomedical Research Center, Queen Mary University of London, London, UK. m.j.caulfield@qmul.ac.uk.
Publikováno v:
Nature genetics [Nat Genet] 2018 Oct; Vol. 50 (10), pp. 1412-1425. Date of Electronic Publication: 2018 Sep 17.
Autor:
Ehret GB; Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.; Cardiology, Department of Medicine, Geneva University Hospital, Rue Gabrielle-Perret-Gentil 4, 1211 Geneva 14, Switzerland., Ferreira T; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK., Chasman DI; Division of Preventive Medicine, Brigham and Women's Hospital, 900 Commonwealth Ave. East, Boston, MA 02215, USA.; Harvard Medical School, Boston, MA 02115, USA., Jackson AU; Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA.; Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA., Schmidt EM; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA., Johnson T; Clinical Pharmacology, William Harvey Research Institute, Queen Mary University of London, London, EC1M 6BQ, UK.; GlaxoSmithKline, Gunnels Wood Road, Stevenage SG1 2NY, UK., Thorleifsson G; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Luan J; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK., Donnelly LA; Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee, DD1 9SY, UK., Kanoni S; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Petersen AK; Institute of Genetic Epidemiology, Helmholtz Zentrum München, Neuherberg 85764, Germany., Pihur V; Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Strawbridge RJ; Cardiovascular Research Unit, Center for Molecular Medicine L8:03, Department of Medicine, Karolinska Institutet, 171 76 Stockholm, Sweden.; Center for Molecular Medicine, Karolinska University Hospital Solna, Stockholm, Sweden., Shungin D; Department of Public Health and Clinical Medicine, Umeå University, Sweden.; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Skåne University Hospital Malmö, SE-205 02 Malmö, Sweden.; Department of Odontology, Umeå University, Sweden., Hughes MF; Centre of Excellence for Public Health, Queens University Belfast, Grosvenor Road, Belfast BT126JP, UK., Meirelles O; Laboratory of Genetics, Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, Maryland 21224, USA., Kaakinen M; Department of Genomics of Common Disease, School of Public Health, Imperial College London, Hammersmith Hospital, London, UK., Bouatia-Naji N; INSERM UMR970, Paris Cardiovascular Research Center PARCC, 56 rue Leblanc, 75015 Paris, France.; University Paris-Descartes, Sorbonne Paris Cité, 12 rue de l'Ecole de medicine, F-75006 Paris, France., Kristiansson K; National Institute for Health and Welfare, FI-00271 Helsinki, Finland.; Institute for Molecular Medicine Finland FIMM, University of Helsinki, 00290 Helsinki, Finland., Shah S; Genetic Epidemiology Group, Dept. Epidemiology and Public Health, UCL, London, WC1E 6BT, UK., Kleber ME; Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany., Guo X; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, 1124 W. Carson Street, Torrance, CA 90502, USA., Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories, Tampere 33520, Finland.; Department of Clinical Chemistry, University of Tampere School of Medicine, Tampere 33014, Finland., Fava C; University of Lund, Dept Internal Medicine, Malmo, SE 20502, Sweden.; University of Verona, Dept of Internal Medicine, Verona, Italy 37134., Eriksson N; Uppsala University, Uppsala Clinical Research Center, SE-75185 Uppsala, Sweden., Nolte IM; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands., Magnusson PK; Dept of Medical Epidemiology and Biostatistics, Karolinska Institutet, Box 281, SE-171 77 Stockholm, Sweden., Salfati EL; Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA., Rallidis LS; Second Department of Cardiology, Attikon Hospital, School of Medicine, University of Athens, Athens, Greece., Theusch E; Children's Hospital Oakland Research Institute, Oakland, CA 94609, USA., Smith AJP; Department of Cardiovascular Genetics, Institute of Cardiovascular Sciences, University College London, London WC1E 6JF, UK., Folkersen L; Cardiovascular Research Unit, Center for Molecular Medicine L8:03, Department of Medicine, Karolinska Institutet, 171 76 Stockholm, Sweden., Witkowska K; Clinical Pharmacology, William Harvey Research Institute, Queen Mary University of London, London, EC1M 6BQ, UK.; NIHR Barts Cardiovascular Biomedical Research Unit, Queen Mary University of London, London, EC1M 6BQ, UK., Pers TH; Division of Endocrinology, Boston Children's Hospital, Boston, MA 02115, USA.; Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA 02115, USA.; Program in Medical and Population Genetics, Broad Institute, 7 Cambridge Center, Cambridge, MA 02142, USA.; Novo Nordisk Foundation Centre for Basic Metabolic Research, Section of Metabolic, Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, 2100, Denmark.; Department of Epidemiology Research, Statens Serum Institut, 2300, Copenhagen, Denmark., Joehanes R; National Heart, Lung and Blood Institute's Framingham Heart Study, Framingham, MA 01702, USA., Kim SK; Dept. Dev. Bio. And Genetics, Stanford University Medical Center, Stanford, CA 94305, USA., Lataniotis L; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Jansen R; Department of Psychiatry, VU University Medical Center, Amsterdam, The Netherlands., Johnson AD; National Heart, Lung and Blood Institute's Framingham Heart Study, Framingham, MA 01702, USA.; National Heart, Lung and Blood Institute, Cardiovascular Epidemiology and Human Genomics Branch, Bethesda, MD 20814, USA., Warren H; Clinical Pharmacology, William Harvey Research Institute, Queen Mary University of London, London, EC1M 6BQ, UK.; NIHR Barts Cardiovascular Biomedical Research Unit, Queen Mary University of London, London, EC1M 6BQ, UK., Kim YJ; Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do, Republic of Korea., Zhao W; Division of Translational Medicine and Human Genetics, Department of Medicine, University of Pennyslvania, USA., Wu Y; Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA., Tayo BO; Department of Preventive Medicine and Epidemiology, Loyola University Chicago Stritch School of Medicine, Maywood, IL, 60153, USA., Bochud M; Institute of Social and Preventive Medicine (IUMSP), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Route de la Corniche 10, 1010 Lausanne, Switzerland., Absher D; HudsonAlpha Institute for Biotechnology, Huntsville, AL 35086, USA., Adair LS; Department of Nutrition, University of North Carolina, Chapel Hill, NC 27599, USA., Amin N; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus MC, Rotterdam, 3015CN, The Netherlands., Arking DE; Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Axelsson T; Uppsala University, Department of Medical Sciences, SE-75185 Uppsala, Sweden., Baldassarre D; Dipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano, Milan, Italy.; Centro Cardiologico Monzino, IRCCS, Milan, Italy., Balkau B; INSERM Centre for Research in Epidemiology and Population Health, U1018, Villejuif, France University Paris-Sud, URMS 1018, Villejuif, France., Bandinelli S; Geriatric Unit, Azienda Sanitaria Firenze (ASF), Florence, Italy., Barnes MR; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; NIHR Barts Cardiovascular Biomedical Research Unit, Queen Mary University of London, London, EC1M 6BQ, UK., Barroso I; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, CB10 1SA, Hinxton, UK.; University of Cambridge Metabolic Research Laboratories, Level 4, Institute of Metabolic Science Box 289 Addenbrookes Hospital Cambridge CB2 OQQ, UK.; NIHR Cambridge Biomedical Research Centre, Level 4, Institute of Metabolic Science Box 289 Addenbrookes Hospital Cambridge CB2 OQQ, UK., Bevan S; School of Life Science, University of Lincoln, Joseph Banks Laboratories, Lincoln LN6 7DL, UK., Bis JC; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA 98101, USA., Bjornsdottir G; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Boehnke M; Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA.; Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA., Boerwinkle E; Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston, 1200 Pressler St., Suite 453E, Houston, TX 77030, USA., Bonnycastle LL; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, MD 20892, USA., Boomsma DI; Department of Biological Psychology, VU University, Amsterdam, The Netherlands., Bornstein SR; Dept of Medicine III, University of Dresden, Medical Faculty Carl Gustav Carus, Fetscherstrasse 74, 01307 Dresden, Germany., Brown MJ; The Barts Heart Centre, William Harvey Research Institute, Queen Mary University of London, London EC1M 6BQ, UK., Burnier M; Nephrology, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Bugnon 17, 1005 Lausanne, Switzerland., Cabrera CP; Clinical Pharmacology, William Harvey Research Institute, Queen Mary University of London, London, EC1M 6BQ, UK.; NIHR Barts Cardiovascular Biomedical Research Unit, Queen Mary University of London, London, EC1M 6BQ, UK., Chambers JC; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, Norfolk Place, London W2 1PG, UK.; Department of Cardiology, Ealing Hospital NHS Trust, Uxbridge Road, Southall, Middlesex UB1 3EU, UK.; Imperial College Healthcare NHS Trust, London, UK., Chang IS; National Institute of Cancer Research, National Health Research Institutes. 35 Keyan Rd., Zhunan Town, Miaoli County 350, Taiwan., Cheng CY; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore 168751, Singapore.; Duke-NUS Graduate Medical School Singapore, Singapore 169857, Singapore.; Department of Ophthalmology, National University of Singapore and National University Health System, Singapore 119228., Chines PS; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, MD 20892, USA., Chung RH; Division of Biostatistics and Bioinformatics, Institute of Population Health Sciences, National Health Research Institutes. 35 Keyan Rd., Zhunan Town, Miaoli County 350, Taiwan., Collins FS; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, MD 20892, USA., Connell JM; University of Dundee, Ninewells Hospital and Medical School, Dundee, DD1 9SY, UK., Döring A; Institute of Epidemiology I, Helmholtz Zentrum München, Neuherberg 85764, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München, Neuherberg 85764, Germany., Dallongeville J; UMR744 Inserm-Lille2-Institut Pasteur Lille, France., Danesh J; Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK.; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, CB10 1SA, Hinxton, UK.; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK., de Faire U; Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Delgado G; Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany., Dominiczak AF; BHF Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, University of Glasgow, 126 University Place, Glasgow, G12 8QT, UK., Doney ASF; Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee, DD1 9SY, UK., Drenos F; Department of Cardiovascular Genetics, Institute of Cardiovascular Sciences, University College London, London WC1E 6JF, UK., Edkins S; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, CB10 1SA, Hinxton, UK., Eicher JD; National Heart, Lung and Blood Institute's Framingham Heart Study, Framingham, MA 01702, USA.; National Heart, Lung and Blood Institute, Cardiovascular Epidemiology and Human Genomics Branch, Bethesda, MD 20814, USA., Elosua R; Cardiovascular Epidemiology and Genetics. IMIM (Institut Hospital del Mar d'Investigacions Mèdiques), Barcelona, Spain., Enroth S; Department of Immunology, Genetics and Pathology, University of Uppsala, Box 815, Biomerical center, 751 08 Uppsala, Sweden.; Science for Life Laboratory, University of Uppsala, Box 815, Biomerical center, 751 08 Uppsala, Sweden., Erdmann J; Institut für Integrative und Experimentelle Genomik, Universiät zu Lübeck, RatzeburgerAllee 160, 23538 Lübeck, Germany.; Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK), partner site Hamburg, Kiel, Lübeck, Universität zu Lübeck, Lübeck, Germany., Eriksson P; Cardiovascular Research Unit, Center for Molecular Medicine L8:03, Department of Medicine, Karolinska Institutet, 171 76 Stockholm, Sweden., Esko T; Estonian Genome Center, University of Tartu, Tartu, 51010, Estonia.; Divisions of Endocrinology/Children's Hospital, Boston, MA 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, MA 02139 USA., Evangelou E; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, Norfolk Place, London W2 1PG, UK.; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, 45110, Greece., Evans A; Centre of Excellence for Public Health, Queens University Belfast, Grosvenor Road, Belfast BT126JP, UK., Fall T; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Farrall M; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, OX3 9DU, UK., Felix JF; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, P.O.Box 2040, 3000 CA Rotterdam, The Netherlands., Ferrières J; Toulouse University School of Medicine, Rangueil University Hospital, INSERM UMR1027, Toulouse, France., Ferrucci L; Translational Gerontology Branch, National Institute on Aging, Baltimore MD, USA., Fornage M; Institute of Molecular Medicine, University of Texas Health Science Center at Houston, TX, USA., Forrester T; Tropical Metabolism Research Unit, Tropical Medicine Research Institute, University of the West Indies, Mona, Kingston 7, Jamaica., Franceschini N; Department of Epidemiology, University of North Carolina, Chapel Hill, NC 27599, USA., Duran OHF; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, P.O.Box 2040, 3000 CA Rotterdam, The Netherlands., Franco-Cereceda A; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, 45110, Greece., Fraser RM; Institute for Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland.; Synpromics Ltd, 9 Bioquarter, Little France Road, Edinburgh, EH16 4UX, Scotland., Ganesh SK; University of Michigan Medical School, 7220 MSRB III, Ann Arbor MI 48109, USA., Gao H; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, Norfolk Place, London W2 1PG, UK., Gertow K; Cardiovascular Research Unit, Center for Molecular Medicine L8:03, Department of Medicine, Karolinska Institutet, 171 76 Stockholm, Sweden.; Center for Molecular Medicine, Karolinska University Hospital Solna, Stockholm, Sweden., Gianfagna F; EPIMED Research Centre - Epidemiology and Preventive Medicine, Department of Clinical and Experimental Medicine, University of Insubria, Varese, Italy.; Department of Epidemiology and Prevention, IRCCS Istituto Neurologico Mediterraneo NEUROMED, 86077 Pozzilli, Italy., Gigante B; Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Giulianini F; Division of Preventive Medicine, Brigham and Women's Hospital, 900 Commonwealth Ave. East, Boston, MA 02215, USA., Goel A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, OX3 9DU, UK., Goodall AH; Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester LE3 9QP, UK.; National Institute for Health Research Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester LE3 9QP, UK., Goodarzi MO; Division of Endocrinology, Diabetes and Metabolism, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Gorski M; Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, Franz-Josef-Strauss-Allee 11, 93053 Regensburg, Germany.; Department of Nephrology, University Hospital Regensburg, Franz-Josef-Strauss-Allee 11, 93053 Regensburg, Germany., Gräßler J; Department of Medicine III, Division Pathobiochemistry, Technische Universität Dresden, Dresden, Germany., Groves C; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK., Gudnason V; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Gyllensten U; Department of Immunology, Genetics and Pathology, University of Uppsala, Box 815, Biomerical center, 751 08 Uppsala, Sweden.; Science for Life Laboratory, University of Uppsala, Box 815, Biomerical center, 751 08 Uppsala, Sweden., Hallmans G; Department of Public Health and Clinical Medicine, Umeå University, Sweden., Hartikainen AL; Institute of Clinical Medicine/Obstetrics and Gynaecology, University of Oulu, Oulu, Finland.; Medical Research Center, Oulu University Hospital, Oulu, Finland., Hassinen M; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Havulinna AS; National Institute for Health and Welfare, FI-00271 Helsinki, Finland., Hayward C; Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, EH4 2XU Scotland, UK., Hercberg S; UREN, INSERM U557, INRA U1125, CNAM, SMBH, Sorbonne Paris Cité, Université Paris 13, Bobigny, France., Herzig KH; Institute of Biomedicine, University of Oulu, Medical Research Center Oulu and Oulu University Hospital, Finland.; Biocenter Oulu, P.O.Box 5000, Aapistie 5A, FI-90014 University of Oulu, Finland.; Department of Gastroenterology and Metabolism, Poznan University of Medical Sciences, Poznan, Poland., Hicks AA; Center for Biomedicine, European Academy Bozen/Bolzano (EURAC), Bolzano, 39100, Italy - affiliated institute of the University of Lübeck, Germany., Hingorani AD; Genetic Epidemiology Group, Dept. Epidemiology and Public Health, UCL, London, WC1E 6BT, UK., Hirschhorn JN; Division of Endocrinology, Boston Children's Hospital, Boston, MA 02115, USA.; Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA 02115, USA.; Program in Medical and Population Genetics, Broad Institute, 7 Cambridge Center, Cambridge, MA 02142, USA.; Department of Genetics, Harvard Medical School, Boston, 02115, USA., Hofman A; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, P.O.Box 2040, 3000 CA Rotterdam, The Netherlands.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Holmen J; HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, 7600 Levanger, Norway., Holmen OL; HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, 7600 Levanger, Norway.; St. Olav Hospital, Trondheim University Hospital, Trondheim, Norway., Hottenga JJ; Department of Biological Psychology, VU University, Amsterdam, The Netherlands., Howard P; Department of Cardiovascular Genetics, Institute of Cardiovascular Sciences, University College London, London WC1E 6JF, UK., Hsiung CA; Division of Biostatistics and Bioinformatics, Institute of Population Health Sciences, National Health Research Institutes. 35 Keyan Rd., Zhunan Town, Miaoli County 350, Taiwan., Hunt SC; Cardiovascular Genetics Division, University of Utah School of Medicine, Salt Lake City, Utah, USA.; Department of Genetic Medicine, Weill Cornell Medical College Qatar, Doha, Qatar., Ikram MA; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, P.O.Box 2040, 3000 CA Rotterdam, The Netherlands.; Department of Radiology, Erasmus MC, The Netherlands.; Department of Neurology, Erasmus MC, University Medical Center Rotterdam, P.O.Box 2040, 3000 CA Rotterdam, The Netherlands., Illig T; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, Neuherberg 85764, Germany.; Hannover Unified Biobank, Hannover Medical School, Hannover 30625, Germany.; Hannover Medical School, Institute for Human Genetics, Carl-Neuberg-Strasse 1, 30625 Hanover, Germany., Iribarren C; Kaiser Permanente, Division of Research, Oakland, CA 94612, USA., Jensen RA; Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston, 1200 Pressler St., Suite 453E, Houston, TX 77030, USA.; Department of Medicine, University of Washington, Seattle, Washington 98101, USA., Kähönen M; Department of Clinical Physiology, Tampere University Hospital, Tampere 33521, Finland., Kang H; Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA.; Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA., Kathiresan S; Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA 02114, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA 02114, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute, 7 Cambridge Center, Cambridge, MA 02142, USA.; Cardiology Division, Department of Medicine, Massachusetts General Hospital., Keating BJ; Division of Transplantation, Department of Surgery, University of Pennsylvania, PA 19104 USA.; Department of Pediatrics, University of Pennsylvania, Philadelphia, PA, USA., Khaw KT; Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge, Cambridge CB2 2SR, UK., Kim YK; Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do, Republic of Korea., Kim E; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, 1124 W. Carson Street, Torrance, CA 90502, USA., Kivimaki M; Genetic Epidemiology Group, Dept. Epidemiology and Public Health, UCL, London, WC1E 6BT, UK., Klopp N; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, Neuherberg 85764, Germany.; Hannover Unified Biobank, Hannover Medical School, Hannover 30625, Germany., Kolovou G; 1st Cardiology Department, Onassis Cardiac Surgery Center 356, Sygrou Ave, Athens, Greece., Komulainen P; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Kooner JS; National Heart and Lung Institute, Imperial College London, Hammersmith Hospital Campus, Ducane Road, London W12 0NN, UK.; Department of Cardiology, Ealing Hospital NHS Trust, Uxbridge Road, Southall, Middlesex UB1 3EU, UK.; Imperial College Healthcare NHS Trust, London, UK., Kosova G; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA 02114, USA.; Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA 02114, USA.; Broad Institute of Harvard and MIT, Cambridge, MA 02139 USA., Krauss RM; Department of Medicine, Children's Hospital Oakland Research Institute, Oakland, CA 94609, USA., Kuh D; MRC Unit for Lifelong Health and Ageing at UCL, London, WC1B 5JU, UK., Kutalik Z; Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Kuusisto J; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, 70210 Kuopio, Finland., Kvaløy K; HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, 7600 Levanger, Norway., Lakka TA; Institute of Biomedicine/Physiology, University of Eastern Finland, Kuopio Campus, Finland.; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland., Lee NR; Office of Population Studies Foundation Inc., Talamban, Cebu City, 6000, Philippines.; Department of Anthropology, Sociology, and History, University of San Carlos, Talamban, Cebu City, 6000, Philippines., Lee IT; Division of Endocrine and Metabolism, Department of Internal Medicine, Chichung Veterans General Hospital, Taichung 40705, Taiwan.; School of Medicine, National Yang-Ming University, Taipei, Taiwan., Lee WJ; Department of Medical Research, Taichung Veterans General Hospital, Taichung 407, Taiwan., Levy D; National Heart, Lung and Blood Institute's Framingham Heart Study, Framingham, MA 01702, USA.; Population Sciences Branch, National Heart Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA., Li X; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, 1124 W. Carson Street, Torrance, CA 90502, USA., Liang KW; Cardiovascular Center, Taichung Veterans General Hospital, Taichung, 40705, Taiwan.; Institute of Clinical Medicine, National Yang Ming University School of Medicine, Taipei 112, Taiwan., Lin H; Section of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, Boston, 02446 MA, USA.; National Heart, Lung and Blood Institute's Framingham Heart Study, Framingham, MA 01702, USA., Lin L; Cardiology, Department of Medicine, Geneva University Hospital, Rue Gabrielle-Perret-Gentil 4, 1211 Geneva 14, Switzerland., Lindström J; National Institute for Health and Welfare, FI-00271 Helsinki, Finland., Lobbens S; European Genomic Institute for Diabetes (EGID), FR 3508 Lille, France.; Centre National de la Recherche Scientifique (CNRS) UMR 8199, Lille Pasteur Institute, 1 rue du Prof Calmette, 59019 Lille Cedex, France.; Lille 2 University, Lille, France., Männistö S; National Institute for Health and Welfare, FI-00271 Helsinki, Finland., Müller G; Center for Evidence-based Healthcare, University of Dresden, Medical Faculty Carl Gustav Carus, Fetscherstrasse 74, 01307 Dresden, Germany., Müller-Nurasyid M; Institute of Genetic Epidemiology, Helmholtz Zentrum München, Neuherberg 85764, Germany.; Department of Medicine I, University Hospital Grosshadern, Ludwig-Maximilians University, Munich, Germany.; Institute of Medical Informatics, Biometry and Epidemiology, Chair of Epidemiology, Ludwig-Maximilians-Universität, München 81377, Germany., Mach F; Cardiology, Department of Medicine, Geneva University Hospital, Rue Gabrielle-Perret-Gentil 4, 1211 Geneva 14, Switzerland., Markus HS; Neurology Unit, University of Cambridge, R3, Box 83, Cambridge Biomedical Campus, Cambridge, Cb2 0QQ, UK., Marouli E; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Department of Dietetics-Nutrition, Harokopio University, 70 El. Venizelou Str, Athens, Greece., McCarthy MI; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK., McKenzie CA; Tropical Metabolism Research Unit, Tropical Medicine Research Institute, University of the West Indies, Mona, Kingston 7, Jamaica., Meneton P; INSERM U1142 LIMICS, UMR_S 1142 Sorbonne Universités, UPMC Université Paris 06, Université Paris 13, Paris, France., Menni C; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Metspalu A; Estonian Genome Center, University of Tartu, Tartu, 51010, Estonia., Mijatovic V; Department of Life and Reproduction Sciences, University of Verona, Strada le Grazie 8, 37134 Verona, Italy., Moilanen L; Department of Medicine, Kuopio University Hospital, Kuopio, Finland.; Unit of General Practice, Oulu University Hospital, Oulu, Finland., Montasser ME; Department of Medicine, Program for Personalized and Genomic Medicine, University of Maryland, School of Medicine, Baltimore, Maryland 21201, USA., Morris AD; Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee, DD1 9SY, UK., Morrison AC; Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, 1200 Pressler St., Suite 453E, Houston, TX 77030, USA., Mulas A; Istituto di Ricerca Genetica e Biomedica (IRGB), Consiglio Nazionale delle Ricerche, c/o Cittadella Universitaria di Monseratto, Monserrato, Cagliari 09042, Italy., Nagaraja R; Laboratory of Genetics, Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, Maryland 21224, USA., Narisu N; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, MD 20892, USA., Nikus K; Department of Cardiology, School of Medicine, University of Tampere, Tampere 33014, Finland.; School of Medicine, University of Tampere, Tampere 33014, Finland., O'Donnell CJ; National Heart, Lung and Blood Institute, Division of Intramural Research, Bethesda, MD, USA.; National Heart, Lung and Blood Institute's Framingham Heart Study, Framingham, MA 01702, USA.; Cardiology Division, Department of Medicine, Massachusetts General Hospital., O'Reilly PF; Institute of Psychiatry, Psychology and Neuroscience, King's College London, London SE5 8AF, UK., Ong KK; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK., Paccaud F; Institute of Social and Preventive Medicine (IUMSP), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Route de la Corniche 10, 1010 Lausanne, Switzerland., Palmer CD; Divisions of Endocrinology, Children's Hospital Boston, Massachusetts 02115, USA.; Genetics and Program in Genomics, Children's Hospital Boston, Massachusetts 02115, USA.; Program in Medical and Population Genetics, Broad Institute, 7 Cambridge Center, Cambridge, MA 02142, USA., Parsa A; Department of Medicine, Program for Personalized and Genomic Medicine, University of Maryland, School of Medicine, Baltimore, Maryland 21201, USA., Pedersen NL; Dept of Medical Epidemiology and Biostatistics, Karolinska Institutet, Box 281, SE-171 77 Stockholm, Sweden., Penninx BW; Department of Psychiatry, EMGO Institute, Neuroscience Campus, VU University Medical Centre, Van der Boechorststraat 7, 1081 BT Amsterdam, The Netherlands.; Department of Psychiatry, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.; Department of Psychiatry, Leiden University Medical Centre, P.O. Box 9600, 2300 RC Leiden, The Netherlands., Perola M; National Institute for Health and Welfare, FI-00271 Helsinki, Finland.; Institute for Molecular Medicine Finland FIMM, University of Helsinki, 00290 Helsinki, Finland.; Estonian Genome Center, University of Tartu, Tartu, 51010, Estonia., Peters A; Institute of Epidemiology II, Helmholtz Zentrum München, Neuherberg 85764, Germany., Poulter N; International Centre for Circulatory Health, Imperial College London, W2 1PG, UK., Pramstaller PP; Center for Biomedicine, European Academy Bozen/Bolzano (EURAC), Bolzano, 39100, Italy - affiliated institute of the University of Lübeck, Germany.; Department of Neurology, General Central Hospital, Bolzano, 39100, Italy.; Department of Neurology, University of Lübeck, Lübeck, Germany., Psaty BM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA 98101, USA.; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Department of Health Services, University of Washington, Seattle, WA.; Group Health Research Institute, Group Health Cooperative, Seattle, WA., Quertermous T; Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA., Rao DC; Division of Biostatistics, Washington University School of Medicine, Saint Louis, MO, 63110, USA., Rasheed A; Center for Non-Communicable Diseases, Karachi, Pakistan., Rayner NWNWR; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, CB10 1SA, Hinxton, UK., Renström F; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Skåne University Hospital Malmö, SE-205 02 Malmö, Sweden.; Department of Nutrition, Harvard School of Public Health, Boston, MA, USA.; Department of Public Health and Clinical Medicine, Umeå University, Sweden., Rettig R; Institute of Physiology, University Medicine Greifswald, Greifswald, Germany., Rice KM; Department of Biostatistics, University of Washington, Seattle, WA, USA., Roberts R; University of Ottawa Heart Institute, Cardiovascular Research Methods Centre Ontario, Canada.; Ruddy Canadian Cardiovascular Genetics Centre, Ontario, Canada., Rose LM; Division of Preventive Medicine, Brigham and Women's Hospital, 900 Commonwealth Ave. East, Boston, MA 02215, USA., Rossouw J; National Heart, Lung, and Blood Institute, 6701 Rockledge Ave., Bethesda, MD 20892, USA., Samani NJ; Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester LE3 9QP, UK.; Leicester NIHR Biomedical Research Unit in Cardiovascular Disease, Glenfield Hospital, Leicester LE3 9QP, UK., Sanna S; Istituto di Ricerca Genetica e Biomedica (IRGB), Consiglio Nazionale delle Ricerche, c/o Cittadella Universitaria di Monseratto, Monserrato, Cagliari 09042, Italy., Saramies J; South Karelia Central Hospital, Lappeenranta, Finland., Schunkert H; Deutsches Herzzentrum München, Germany.; Technische Universität München, Germany.; Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK), München, Germany.; Munich Heart Alliance, Germany., Sebert S; Center For Life-course Health Research, P.O.Box 5000, FI-90014 University of Oulu, Finland.; Biocenter Oulu, P.O.Box 5000, Aapistie 5A, FI-90014 University of Oulu, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland., Sheu WH; Division of Endocrine and Metabolism, Department of Internal Medicine, Chichung Veterans General Hospital, Taichung 40705, Taiwan.; School of Medicine, National Yang-Ming University, Taipei, Taiwan.; College of Medicine, National Defense Medical Center, Taipei, Taiwan., Shin YA; Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do, Republic of Korea., Sim X; Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA.; Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA.; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore 117597., Smit JH; Department of Psychiatry, EMGO Institute, Neuroscience Campus, VU University Medical Centre, Van der Boechorststraat 7, 1081 BT Amsterdam, The Netherlands., Smith AV; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Sosa MX; Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Spector TD; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Stančáková A; University of Eastern Finland and Kuopio University Hospital, 70210 Kuopio, Finland., Stanton A; Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin 4, Ireland., Stirrups KE; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Department of Haematology, University of Cambridge, Cambridge, UK., Stringham HM; Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA.; Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA., Sundstrom J; Uppsala University, Department of Medical Sciences, SE-75185 Uppsala, Sweden., Swift AJ; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, MD 20892, USA., Syvänen AC; Uppsala University, Department of Medical Sciences, SE-75185 Uppsala, Sweden., Tai ES; Department of Medicine, National University of Singapore and National University Health System, Singapore 119228, Singapore.; Duke-NUS Graduate Medical School Singapore, Singapore 169857, Singapore.; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore 117597., Tanaka T; Translational Gerontology Branch, National Institute on Aging, Baltimore MD, USA., Tarasov KV; Laboratory of Cardiovascular Science, Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, 21224, USA., Teumer A; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany., Thorsteinsdottir U; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Tobin MD; Department of Health Sciences, University of Leicester, University Rd, Leicester LE1 7RH, UK., Tremoli E; Dipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano, Milan, Italy.; Centro Cardiologico Monzino, IRCCS, Milan, Italy., Uitterlinden AG; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, P.O.Box 2040, 3000 CA Rotterdam, The Netherlands.; Department of internal medicine, Erasmus MC, Rotterdam, 3000CA, The Netherlands., Uusitupa M; Department of Public Health and Clinical Nutrition, University of Eastern Finland, Finland.; Research Unit, Kuopio University Hospital, Kuopio, Finland., Vaez A; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.; Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran., Vaidya D; Johns Hopkins Medical Institutions, 1830 East Monument St., Baltimore, MD 21287, USA., van Duijn CM; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, P.O.Box 2040, 3000 CA Rotterdam, The Netherlands.; Centre of Medical Systems Biology (CMSB 1-2), NGI Erasmus Medical Center, Rotterdam, The Netherlands., van Iperen EPA; Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Center, Amsterdam, The Netherlands.; Durrer Center for Cardiogenetic Research, ICIN-Netherlands Heart Institute, Utrecht, The Netherlands., Vasan RS; National Heart, Lung and Blood Institute's Framingham Heart Study, Framingham, MA 01702, USA.; Section of Preventive medicine, Department of Medicine, Boston University School of Medicine, Boston, 02446 MA, USA.; Cardiology, Department of Medicine, Boston University School of Medicine, Boston, 02446 MA, USA., Verwoert GC; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, P.O.Box 2040, 3000 CA Rotterdam, The Netherlands., Virtamo J; National Institute for Health and Welfare, FI-00271 Helsinki, Finland., Vitart V; Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, EH4 2XU Scotland, UK., Voight BF; Program in Medical and Population Genetics, Broad Institute, 7 Cambridge Center, Cambridge, MA 02142, USA.; Department of Pharmacology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA., Vollenweider P; Department of Internal medicine, University Hospital Lausanne, Lausanne, Switzerland., Wagner A; Department of Epidemiology and Public Health, EA3430, University of Strasbourg, Strasbourg, France., Wain LV; Department of Health Sciences, University of Leicester, University Rd, Leicester LE1 7RH, UK., Wareham NJ; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK., Watkins H; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, OX3 9DU, UK., Weder AB; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA., Westra HJ; University Medical Center Groningen, University of Groningen, Groningen, 9700RB, The Netherlands., Wilks R; Epidemiology Research Unit, Tropical Medicine Research Institute, University of the West Indies, Mona, Kingston 7, Jamaica., Wilsgaard T; Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway.; Department of Clinical Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway., Wilson JF; Institute for Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, Scotland.; Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, EH4 2XU Scotland, UK., Wong TY; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore 168751, Singapore.; Duke-NUS Graduate Medical School Singapore, Singapore 169857, Singapore.; Department of Ophthalmology, National University of Singapore and National University Health System, Singapore 119228., Yang TP; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; MRC Cancer Unit, University of Cambridge, Cambridge, UK., Yao J; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, 1124 W. Carson Street, Torrance, CA 90502, USA., Yengo L; European Genomic Institute for Diabetes (EGID), FR 3508 Lille, France.; Centre National de la Recherche Scientifique (CNRS) UMR 8199, Lille Pasteur Institute, 1 rue du Prof Calmette, 59019 Lille Cedex, France.; Lille 2 University, Lille, France., Zhang W; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, Norfolk Place, London W2 1PG, UK.; Department of Cardiology, Ealing Hospital NHS Trust, Uxbridge Road, Southall, Middlesex UB1 3EU, UK., Zhao JH; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK., Zhu X; Department of Epidemiology and Biostatistics, School of Medicine, Case Western Reserve University, Cleveland, OH, 44106, USA., Bovet P; Ministry of Health, Victoria, Republic of Seychelles.; Institute of Social and Preventive Medicine (IUMSP), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Route de la Corniche 10, 1010 Lausanne, Switzerland., Cooper RS; Department of Preventive Medicine and Epidemiology, Loyola University Chicago Stritch School of Medicine, Maywood, IL, 60153, USA., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA., Saleheen D; Department of Biostatistics and Epidemiology, University of Pennsylvania, USA.; Center for Non-Communicable Diseases, Karachi, Pakistan., Lee JY; Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do, Republic of Korea., Elliott P; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, Norfolk Place, London W2 1PG, UK.; MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, Norfolk Place, London W2 1PG, UK., Gierman HJ; Dept. Dev. Bio. And Genetics, Stanford University Medical Center, Stanford, CA 94305, USA.; Enterprise Informatics, Illumina Inc., Santa Clara CA, 95050, USA., Willer CJ; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA.; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI 48109, USA.; Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, USA., Franke L; Department of Genetics, University of Groningen, University Medical Centre Groningen, Groningen, 9711, The Netherlands., Hovingh GK; Dept Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands., Taylor KD; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, 1124 W. Carson Street, Torrance, CA 90502, USA., Dedoussis G; Department of Dietetics-Nutrition, Harokopio University, 70 El. Venizelou Str, Athens, Greece., Sever P; International Centre for Circulatory Health, Imperial College London, W2 1PG, UK., Wong A; MRC Unit for Lifelong Health and Ageing at UCL, London, WC1B 5JU, UK., Lind L; Uppsala University, Department of Medical Sciences, SE-75185 Uppsala, Sweden., Assimes TL; Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA., Njølstad I; Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway.; Department of Clinical Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway., Schwarz PE; Dept of Medicine III, University of Dresden, Medical Faculty Carl Gustav Carus, Fetscherstrasse 74, 01307 Dresden, Germany., Langenberg C; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK., Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands., Caulfield MJ; Clinical Pharmacology, William Harvey Research Institute, Queen Mary University of London, London, EC1M 6BQ, UK.; NIHR Barts Cardiovascular Biomedical Research Unit, Queen Mary University of London, London, EC1M 6BQ, UK., Melander O; University of Lund, Dept Internal Medicine, Malmo, SE 20502, Sweden., Laakso M; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, 70210 Kuopio, Finland., Saltevo J; Department of Medicine, Central Finland Health Care District, Jyväskylä, Finland., Rauramaa R; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland., Tuomilehto J; National Institute for Health and Welfare, FI-00271 Helsinki, Finland.; Dasman Diabetes Institute, Dasman, 15462 Kuwait.; Saudi Diabetes Research Group, King Abdulaziz University, 21589 Jeddah, Saudi Arabia.; Centre for Vascular Prevention, Danube-University Krems, 3500 Krems, Austria., Ingelsson E; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Tampere 33520, Finland.; Department of Clinical Chemistry, University of Tampere School of Medicine, Tampere 33014, Finland., Hveem K; HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, 7600 Levanger, Norway., Palmas W; Department of Medicine, Columbia University, 622 West 168th St., New York, NY 10032, USA., März W; Synlab Academy, Synlab Services GmbH, P5, 7, 68161 Mannheim, Germany.; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, 8036 Graz, Austria., Kumari M; Genetic Epidemiology Group, Dept. Epidemiology and Public Health, UCL, London, WC1E 6BT, UK., Salomaa V; National Institute for Health and Welfare, FI-00271 Helsinki, Finland., Chen YI; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, 1124 W. Carson Street, Torrance, CA 90502, USA., Rotter JI; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, 1124 W. Carson Street, Torrance, CA 90502, USA., Froguel P; European Genomic Institute for Diabetes (EGID), FR 3508 Lille, France.; Centre National de la Recherche Scientifique (CNRS) UMR 8199, Lille Pasteur Institute, 1 rue du Prof Calmette, 59019 Lille Cedex, France.; Lille 2 University, Lille, France.; Department of Genomics of Common Disease, School of Public Health, Imperial College London, Hammersmith Hospital, London, UK., Jarvelin MR; Center For Life-course Health Research, P.O.Box 5000, FI-90014 University of Oulu, Finland.; Biocenter Oulu, P.O.Box 5000, Aapistie 5A, FI-90014 University of Oulu, Finland.; Unit of Primary Care, Oulu University Hospital, Kajaanintie 50, P.O.Box 20, FI-90220 Oulu, 90029 OYS, Finland.; MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, Norfolk Place, London W2 1PG, UK., Lakatta EG; Laboratory of Cardiovascular Science, Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, 21224, USA., Kuulasmaa K; National Institute for Health and Welfare, FI-00271 Helsinki, Finland., Franks PW; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Skåne University Hospital Malmö, SE-205 02 Malmö, Sweden.; Department of Nutrition, Harvard School of Public Health, Boston, MA, USA.; Department of Public Health and Clinical Medicine, Umeå University, Sweden., Hamsten A; Cardiovascular Research Unit, Center for Molecular Medicine L8:03, Department of Medicine, Karolinska Institutet, 171 76 Stockholm, Sweden.; Center for Molecular Medicine, Karolinska University Hospital Solna, Stockholm, Sweden., Wichmann HE; Institute of Epidemiology I, Helmholtz Zentrum München, Neuherberg 85764, Germany.; Institute of Medical Informatics, Biometry and Epidemiology, Chair of Epidemiology, Ludwig-Maximilians-Universität, München 81377, Germany.; Grosshadern, Klinikum, München 81377, Germany., Palmer CNA; Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee, DD1 9SY, UK., Stefansson K; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Ridker PM; Division of Preventive Medicine, Brigham and Women's Hospital, 900 Commonwealth Ave. East, Boston, MA 02215, USA.; Harvard Medical School, Boston, MA 02115, USA., Loos RJF; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK.; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Mindich Child health Development Institute, The Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Chakravarti A; Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Deloukas P; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah 21589, Saudi Arabia., Morris AP; Department of Biostatistics, University of Liverpool, Liverpool L69 3GA, UK.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK., Newton-Cheh C; Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA 02114, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA 02114, USA.; Program in Medical and Population Genetics, Broad Institute, 7 Cambridge Center, Cambridge, MA 02142, USA.; Broad Institute of Harvard and MIT, Cambridge, MA 02139 USA., Munroe PB; Clinical Pharmacology, William Harvey Research Institute, Queen Mary University of London, London, EC1M 6BQ, UK.; NIHR Barts Cardiovascular Biomedical Research Unit, Queen Mary University of London, London, EC1M 6BQ, UK.
Publikováno v:
Nature genetics [Nat Genet] 2016 Oct; Vol. 48 (10), pp. 1171-1184. Date of Electronic Publication: 2016 Sep 12.
Autor:
Surendran P; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Drenos F; Medical Research Council Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove, Bristol, UK.; Centre for Cardiovascular Genetics, Institute of Cardiovascular Science, Rayne Building University College London, London, UK., Young R; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Warren H; Clinical Pharmacology, William Harvey Research Institute, Queen Mary University of London, London, UK.; National Institute for Health Research Barts Cardiovascular Biomedical Research Unit, Queen Mary University of London, London, UK., Cook JP; Department of Health Sciences, University of Leicester, Leicester, UK.; Department of Biostatistics, University of Liverpool, Liverpool, UK., Manning AK; Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA.; Program in Medical and Population Genetics, Broad Institute, 7 Cambridge Center, Cambridge, Massachusetts, USA.; Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts, USA., Grarup N; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Sim X; Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, USA.; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA.; Saw Swee Hock School of Public Health, National University of Singapore, National University Health System, Singapore., Barnes DR; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Witkowska K; Clinical Pharmacology, William Harvey Research Institute, Queen Mary University of London, London, UK.; National Institute for Health Research Barts Cardiovascular Biomedical Research Unit, Queen Mary University of London, London, UK., Staley JR; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Tragante V; Department of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands., Tukiainen T; Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA.; Program in Medical and Population Genetics, Broad Institute, 7 Cambridge Center, Cambridge, Massachusetts, USA.; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA., Yaghootkar H; Genetics of Complex Traits, Institute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter, UK., Masca N; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; National Institute for Health Research Leicester Biomedical Research Unit in Cardiovascular Disease, Leicester, UK., Freitag DF; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Ferreira T; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Giannakopoulou O; Heart Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Tinker A; Heart Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; National Institute for Health Research Barts Cardiovascular Biomedical Research Unit, Queen Mary University of London, London, UK., Harakalova M; Department of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands., Mihailov E; Estonian Genome Center, University of Tartu, Tartu, Estonia., Liu C; National Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, Massachusetts, USA., Kraja AT; Division of Statistical Genomics, Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, Missouri, USA.; Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, USA., Fallgaard Nielsen S; Department of Clinical Biochemistry Herlev Hospital, Copenhagen University Hospital, Herlev, Denmark., Rasheed A; Centre for Non-Communicable Diseases, Karachi, Pakistan., Samuel M; Centre for Non-Communicable Diseases, Karachi, Pakistan., Zhao W; Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Bonnycastle LL; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland, USA., Jackson AU; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA.; Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, USA., Narisu N; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland, USA., Swift AJ; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland, USA., Southam L; Wellcome Trust Sanger Institute, Genome Campus, Hinxton, UK.; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Marten J; Medical Research Council Human Genetics Unit, Medical Research Council Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Huyghe JR; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA.; Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, USA., Stančáková A; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Fava C; University of Lund, Department of Clinical Sciences, Malmö, Sweden.; University of Verona, Department of Medicine, Verona, Italy., Ohlsson T; University of Lund, Department of Clinical Sciences, Malmö, Sweden., Matchan A; Wellcome Trust Sanger Institute, Genome Campus, Hinxton, UK., Stirrups KE; Heart Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Department of Haematology, University of Cambridge, Cambridge, UK., Bork-Jensen J; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Gjesing AP; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Kontto J; Department of Health, National Institute for Health and Welfare, Helsinki, Finland., Perola M; Department of Health, National Institute for Health and Welfare, Helsinki, Finland.; Institute of Molecular Medicine FIMM, University of Helsinki, Finland.; Estonian Genome Center, University of Tartu, Tartu, Estonia., Shaw-Hawkins S; Clinical Pharmacology, William Harvey Research Institute, Queen Mary University of London, London, UK., Havulinna AS; Department of Health, National Institute for Health and Welfare, Helsinki, Finland., Zhang H; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA., Donnelly LA; Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Groves CJ; Oxford Centre for Diabetes, Endocrinology, and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Rayner NW; Oxford Centre for Diabetes, Endocrinology, and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Wellcome Trust Sanger Institute, Genome Campus, Hinxton, UK., Neville MJ; Oxford Centre for Diabetes, Endocrinology, and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; National Institute for Health Research Oxford Biomedical Research Centre, Oxford University Hospital Trusts, Oxford, UK., Robertson NR; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology, and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Yiorkas AM; Section of Investigative Medicine, Imperial College London, London, UK.; Department of Life Sciences, Brunel University London, London, UK., Herzig KH; Institute of Biomedicine, Biocenter Oulu, University of Oulu, Oulu, Finland.; Department of Gastroenterology and Metabolism, Poznan University of Medical Sciences, Poznan, Poland., Kajantie E; Department of Health, National Institute for Health and Welfare, Helsinki, Finland.; Hospital for Children and Adolescents, Helsinki University Central Hospital and University of Helsinki, Helsinki, Finland.; Department of Obstetrics and Gynaecology, Oulu University Hospital and University of Oulu, Oulu, Finland., Zhang W; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital, Middlesex, UK., Willems SM; Medical Research Council Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, UK., Lannfelt L; Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden., Malerba G; Section of Biology and Genetics, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy., Soranzo N; Human Genetics, Wellcome Trust Sanger Institute, Hinxton, UK.; Department of Haematology, University of Cambridge, Cambridge, UK.; The National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, UK., Trabetti E; Section of Biology and Genetics, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy., Verweij N; University Medical Center Groningen, University of Groningen, Department of Cardiology, The Netherlands.; Program in Medical and Population Genetics, Broad Institute, 7 Cambridge Center, Cambridge, Massachusetts, USA.; Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA., Evangelou E; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece., Moayyeri A; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.; Farr Institute of Health Informatics Research, Institute of Health Informatics, University College London, London, UK., Vergnaud AC; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK., Nelson CP; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; National Institute for Health Research Leicester Biomedical Research Unit in Cardiovascular Disease, Leicester, UK., Poveda A; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Malmö, Sweden.; Department of Genetics, Physical Anthropology and Animal Physiology, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), Bilbao, Spain., Varga TV; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Malmö, Sweden., Caslake M; University of Glasgow, Glasgow, UK., de Craen AJ; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands.; Mr. De Craen suddenly passed away January 2016., Trompet S; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands.; Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands., Luan J; Medical Research Council Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, UK., Scott RA; Medical Research Council Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, UK., Harris SE; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Centre for Genomic and Experimental Medicine, Medical Research Council Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Liewald DC; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., Marioni R; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Centre for Genomic and Experimental Medicine, Medical Research Council Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.; Queensland Brain Institute, The University of Queensland, Brisbane, Queensland, Australia., Menni C; Department of Twin Research and Genetic Epidemiology, King's College London, UK., Farmaki AE; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece., Hallmans G; Department of Biobank Research, Umeå University, Umeå, Sweden., Renström F; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Malmö, Sweden.; Department of Biobank Research, Umeå University, Umeå, Sweden., Huffman JE; Medical Research Council Human Genetics Unit, Medical Research Council Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.; National Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, Massachusetts, USA., Hassinen M; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Burgess S; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Vasan RS; National Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, Massachusetts, USA.; Section of Cardiology, Department of Medicine, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, USA.; Sections of Preventive Medicine and Epidemiology, Department of Medicine, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, USA., Felix JF; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., Uria-Nickelsen M; Development Management and Planning, Pfizer Worldwide Research and Development., Malarstig A; Pfizer Worldwide Research and Development, Stockholm, Sweden., Reily DF; Merck Research Laboratories, Genetics and Pharmacogenomics, Boston, Massachusetts, USA., Hoek M; Merck Research Laboratories, Cardiometabolic Disease, Kenilworth, New Jersey, USA., Vogt T; Merck Research Laboratories, Cardiometabolic Disease, Kenilworth, New Jersey, USA.; CHDI Management/CHDI Foundation, Princeton, New Jersey, USA., Lin H; National Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, Massachusetts, USA.; Section of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, USA., Lieb W; Institute of Epidemiology and Biobank Popgen, Kiel University, Kiel, Germany., Traylor M; Neurology Unit, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK., Markus HF; Neurology Unit, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK., Highland HM; University of North Carolina at Chapel Hill, Department of Epidemiology, Chapel Hill, North Carolina, USA., Justice AE; University of North Carolina at Chapel Hill, Department of Epidemiology, Chapel Hill, North Carolina, USA., Marouli E; Heart Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Lindström J; Department of Health, National Institute for Health and Welfare, Helsinki, Finland., Uusitupa M; Department of Public Health and Clinical Nutrition, University of Eastern Finland, Finland.; Research Unit, Kuopio University Hospital, Kuopio, Finland., Komulainen P; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Lakka TA; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Institute of Biomedicine/Physiology, University of Eastern Finland, Kuopio Campus, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland., Rauramaa R; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland., Polasek O; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.; Faculty of Medicine, University of Split, Croatia., Rudan I; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Rolandsson O; Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden., Franks PW; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Malmö, Sweden.; Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.; Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA., Dedoussis G; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece., Spector TD; Department of Twin Research and Genetic Epidemiology, King's College London, UK., Jousilahti P; Department of Health, National Institute for Health and Welfare, Helsinki, Finland., Männistö S; Department of Health, National Institute for Health and Welfare, Helsinki, Finland., Deary IJ; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., Starr JM; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Alzheimer Scotland Research Centre, University of Edinburgh, Edinburgh, UK., Langenberg C; Medical Research Council Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, UK., Wareham NJ; Medical Research Council Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, UK., Brown MJ; Clinical Pharmacology, William Harvey Research Institute, Queen Mary University of London, London, UK., Dominiczak AF; Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK., Connell JM; Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Jukema JW; Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.; The Interuniversity Cardiology Institute of the Netherlands, Utrecht, The Netherlands., Sattar N; Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK., Ford I; University of Glasgow, Glasgow, UK., Packard CJ; University of Glasgow, Glasgow, UK., Esko T; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Division of Endocrinology, Boston Children's Hospital, Boston, Massachusetts, USA.; Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA.; Program in Medical and Population Genetics, Broad Institute, 7 Cambridge Center, Cambridge, Massachusetts, USA., Mägi R; Estonian Genome Center, University of Tartu, Tartu, Estonia., Metspalu A; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Institute of Molecular and Cell Biology, Tartu, Estonia., de Boer RA; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., van der Meer P; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., van der Harst P; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; Durrer Center for Cardiogenetic Research, ICIN-Netherlands Heart Institute, Utrecht, The Netherlands., Gambaro G; Division of Nephrology, Department of Internal Medicine and Medical Specialties, Columbus - Gemelli University Hospital, Catholic University, Rome, Italy., Ingelsson E; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, California, USA., Lind L; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden., de Bakker PI; Department of Medical Genetics, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.; Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands., Numans ME; Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands.; Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands., Brandslund I; Department of Clinical Biochemistry, Lillebaelt Hospital, Vejle, Denmark.; Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark., Christensen C; Medical Department, Lillebaelt Hospital, Vejle, Denmark., Petersen ER; Department of Clinical Immunology and Biochemistry, Lillebaelt Hospital, Vejle, Denmark., Korpi-Hyövälti E; South Ostrobothnia Central Hospital, Seinäjoki, Finland., Oksa H; Tampere University Hospital, Tampere, Finland., Chambers JC; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital, Middlesex, UK.; Imperial College Healthcare NHS Trust, London, UK., Kooner JS; Department of Cardiology, Ealing Hospital, Middlesex, UK.; National Heart and Lung Institute, Imperial College London, London, UK.; Imperial College Healthcare NHS Trust, London, UK., Blakemore AI; Section of Investigative Medicine, Imperial College London, London, UK.; Department of Life Sciences, Brunel University London, London, UK., Franks S; Institute of Reproductive and Developmental Biology, Imperial College London, London, UK., Jarvelin MR; Department of Epidemiology and Biostatistics, Medical Research Council Public Health England Centre for Environment and Health, School of Public Health, Faculty of Medicine, Imperial College London, St. Mary's Campus, London, UK.; Centre for Life Course Epidemiology, Faculty of Medicine, University of Oulu, Oulu, Finland.; Biocenter Oulu, University of Oulu, Oulu, Finland.; Unit of Primary Care, Oulu University Hospital, Oulu, Finland., Husemoen LL; Research Centre for Prevention and Health, Capital Region of Denmark, Copenhagen, Denmark., Linneberg A; Research Centre for Prevention and Health, Capital Region of Denmark, Copenhagen, Denmark.; Department of Clinical Experimental Research, Glostrup University Hospital, Glostrup, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Skaaby T; Research Centre for Prevention and Health, Capital Region of Denmark, Copenhagen, Denmark., Thuesen B; Research Centre for Prevention and Health, Capital Region of Denmark, Copenhagen, Denmark., Karpe F; Oxford Centre for Diabetes, Endocrinology, and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; National Institute for Health Research Oxford Biomedical Research Centre, Oxford University Hospital Trusts, Oxford, UK., Tuomilehto J; Department of Health, National Institute for Health and Welfare, Helsinki, Finland.; Dasman Diabetes Institute, Dasman, Kuwait.; Centre for Vascular Prevention, Danube-University Krems, Krems, Austria.; King Abdulaziz University, Jeddah, Saudi Arabia., Doney AS; Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Morris AD; School of Molecular, Genetic and Population Health Sciences, University of Edinburgh, Medical School, Teviot Place, Edinburgh, UK., Palmer CN; Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Holmen OL; HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, Norway.; St. Olav Hospital, Trondheim University Hospital, Trondheim, Norway., Hveem K; HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, Norway.; Department of Medicine, Levanger Hospital, Nord- Trøndelag Health Trust, Levanger, Norway., Willer CJ; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA.; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA.; Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, USA., Tuomi T; Folkhälsan Research Centre, Helsinki, Finland; Department of Endocrinology, Helsinki University Central Hospital, Helsinki, Finland.; Institute for Molecular Medicine Finland University of Helsinki, Helsinki, Finland., Groop L; Department of Clinical Sciences, Diabetes and Endocrinology, Lund University Diabetes Centre, Malmö, Sweden.; Institute for Molecular Medicine Finland University of Helsinki, Helsinki, Finland., Käräjämäki A; Department of Primary Health Care, Vaasa Central Hospital, Vaasa, Finland.; Diabetes Center, Vaasa Health Care Center, Vaasa, Finland., Palotie A; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.; Program in Medical and Population Genetics, Broad Institute, 7 Cambridge Center, Cambridge, Massachusetts, USA.; Institute for Molecular Medicine Finland University of Helsinki, Helsinki, Finland.; Psychiatric and Neurodevelopmental Genetics Unit, Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA., Ripatti S; Institute for Molecular Medicine Finland University of Helsinki, Helsinki, Finland.; Department of Public Health, University of Helsinki, Finland.; Wellcome Trust Sanger Institute, Genome Campus, Hinxton, UK., Salomaa V; Department of Health, National Institute for Health and Welfare, Helsinki, Finland., Alam DS; ICDDR, B; Mohakhali, Dhaka, Bangladesh., Shafi Majumder AA; National Institute of Cardiovascular Diseases, Sher-e-Bangla Nagar, Dhaka, Bangladesh., Di Angelantonio E; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; The National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, UK., Chowdhury R; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., McCarthy MI; Oxford Centre for Diabetes, Endocrinology, and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; National Institute for Health Research Oxford Biomedical Research Centre, Oxford University Hospital Trusts, Oxford, UK.; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Poulter N; International Centre for Circulatory Health, Imperial College London, UK., Stanton AV; Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland., Sever P; International Centre for Circulatory Health, Imperial College London, UK., Amouyel P; University of Lille, UMR1167, Risk Factors and Molecular Determinants of aging-related diseases, Lille, France.; Inserm, Lille, France.; Centre Hospitalier Universitaire Lille, Public Health, Lille, France.; Institut Pasteur de Lille, Lille, France., Arveiler D; Department of Epidemiology and Public Health, EA 3430, University of Strasbourg, Strasbourg, France., Blankenberg S; Department of General and Interventional Cardiology, University Heart Center Hamburg, Germany.; University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Ferrières J; Department of Epidemiology, UMR 1027- INSERM, Toulouse University-CHU Toulouse, Toulouse, France., Kee F; Director, UKCRC Centre of Excellence for Public Health, Queens University, Belfast, Northern Ireland., Kuulasmaa K; Department of Health, National Institute for Health and Welfare, Helsinki, Finland., Müller-Nurasyid M; Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.; Department of Medicine I, University Hospital Grosshadern, Ludwig-Maximilians-Universität, Munich, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany., Veronesi G; Research Center in Epidemiology and Preventive Medicine, Department of Clinical and Experimental Medicine, University of Insubria, Varese, Italy., Virtamo J; Department of Health, National Institute for Health and Welfare, Helsinki, Finland., Deloukas P; Heart Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah, Saudi Arabia., Elliott P; Department of Epidemiology and Biostatistics, Medical Research Council Public Health England Centre for Environment and Health, School of Public Health, Faculty of Medicine, Imperial College London, St. Mary's Campus, London, UK., Zeggini E; Wellcome Trust Sanger Institute, Genome Campus, Hinxton, UK., Kathiresan S; Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA.; Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.; Program in Medical and Population Genetics, Broad Institute, 7 Cambridge Center, Cambridge, Massachusetts, USA., Melander O; University of Lund, Department of Clinical Sciences, Malmö, Sweden., Kuusisto J; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Laakso M; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Padmanabhan S; Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK., Porteous D; Centre for Genomic and Experimental Medicine, Medical Research Council Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Hayward C; Medical Research Council Human Genetics Unit, Medical Research Council Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Scotland G; A Collaboration between the University Medical Schools and NHS, Aberdeen, Dundee, Edinburgh and Glasgow, UK., Collins FS; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland, USA., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, USA., Hansen T; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Pedersen O; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Boehnke M; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA.; Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, USA., Stringham HM; 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