Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Mahmoud M. El-Mas"'
Publikováno v:
Saudi Pharmaceutical Journal : SPJ
Saudi Pharmaceutical Journal, Vol 28, Iss 1, Pp 127-135 (2020)
Saudi Pharmaceutical Journal, Vol 28, Iss 1, Pp 127-135 (2020)
Widely different exposure times to endotoxic insults have been employed in reported studies. The current experimental study systematically evaluated the time-course and sex influences of endotoxic insult on survivability and cardiovascular and renal
Publikováno v:
Journal of Cardiovascular Pharmacology.
Inconsistent reports are available on the role of testosterone in end-organ damage caused by endotoxemia. Here, pharmacologic, surgical, and molecular studies were employed to assess the testosterone modulation of cardiovascular, autonomic, and perip
Publikováno v:
Brain research. 1756
Autonomic neuropathy contributes to cardiovascular derangements induced by endotoxemia. In this communication, we tested the hypothesis that androgenic hormones improve arterial baroreflex dysfunction and predisposing neuroinflammatory response cause
Autor:
Mohamed A. Fouda, Hanan M. El-Gowelli, Mohammed A. El-Lakany, Marwa Y. Sallam, Mahmoud M. El-Mas
Publikováno v:
Toxicology letters. 335
Endotoxic manifestations are diminished in female populations due to immune boosting actions of sex steroids. Considering that tobacco constituents including nicotine inhibit estrogen synthesis, we tested the hypothesis that nicotine exposure unveils
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 373(2)
Pre-eclampsia (PE)-induced fetal programming predisposes offspring to health hazards in adult life. Here, we tested the hypothesis that pre-eclamptic fetal programming elicits sexually dimorphic inflammatory and cardiovascular complications to endoto
Publikováno v:
Biomedicine & Pharmacotherapy. 102:309-316
The combined use of cyclosporine (CSA) and nonsteroidal antiinflammatory drugs (NSAIDs) causes exaggerated rises in systolic blood pressure (SBP) and nephrotoxicity. We examined whether these influences relate to the arachidonate/5-lipoxygenase (LOX)
Publikováno v:
Pharmacological Reports. 70:455-462
Chronic nicotine administration impairs reflex chronotropic responses that follow arterial baroreceptor unloading in female rats with repleted, but not depleted (ovariectomized, OVX), estrogen (E2). This study investigated whether products of nitric
Publikováno v:
Biomedicine & Pharmacotherapy. 101:889-897
We recently reported that exposure to cyclosporine (CSA) plus diclofenac causes hypertension and impairs left ventricular (LV) and cardiac autonomic functions in female rats. Here, we tested the hypothesis that these effects could be mitigated by fac
Publikováno v:
Pharmacological Research. 129:251-261
Cyclosporine, the prototype calcineurin inhibitor, transformed immunosuppressant regimens and practices post-organ transplantation. Therapeutic uses of cyclosporine branched out to include management of different autoimmune disorders. However, multip
Publikováno v:
European Journal of Pharmacology. 910:174494
Preeclampsia (PE) is a pregnancy-related disorder with serious maternal complications. Considering the increased importance of postpartum infection in maternal morbidity and mortality, we investigated whether preeclamptic maternal programming alters