Zobrazeno 1 - 10
of 264
pro vyhledávání: '"Blood drug"'
Publikováno v:
Cold Spring Harbor perspectives in biology. 14(4)
Females have long been underrepresented in preclinical research and clinical drug trials. Directives by the U.S. National Institutes of Health have increased female participation in research protocols, although analysis of outcomes by sex remains inf
HSA-Lys-161 covalent bound fluorescent dye for in vivo blood drug dynamic imaging and tumor mapping†
Autor:
Caixia Yin, Yongkang Yue, tingting zhao, Fangqin Cheng, Ma Kaiqing, Wu Xingkang, Yuting Wang, Fangjun Huo
Publikováno v:
Chemical Science
The specific combination of human serum albumin and fluorescent dye will endow superior performance to a coupled fluorescent platform for in vivo fluorescence labeling. In this study, we found that lysine-161 in human serum albumin is a covalent bind
Autor:
Idris Kirhan, Ataman Gönel
Publikováno v:
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry. 20:101-105
Background: Antibiotics used parenterally can affect blood drug level measurements, as measured in diagnostic tests. Objective: To investigate the effect of six different antibiotics commonly used in intensive care units on tacrolimus, sirolimus, eve
Publikováno v:
OncoTargets and therapy
Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor, and surgical resection is the first choice for the treatment of the disease, but since the advent of tyrosine kinase inhibitors (TKIs) such as imatinib (IM), the prognosis of
Autor:
Krasimira Prodanova
Publikováno v:
International Journal Bioautomation, Vol 24, Iss 4, Pp 337-348 (2020)
For the multiple drug administration from therapeutic reasons it is important to maintain the concentration in the blood plasma in an appropriate range. In the present paper an optimization approach is developed to determine drug dosage regimen to ac
Autor:
Olaf H. Drummer, Linda Glowacki, Matthew Di Rago, Dimitri Gerostamoulos, Dylan Mantinieks, Jennifer L. Schumann, Noel Woodford
Publikováno v:
Journal of Analytical Toxicology. 45:368-377
Postmortem drug redistribution (PMR) is a well-known phenomenon in forensic toxicology with implications for medico-legal death investigations. Paired antemortem (AM) specimen and postmortem (PM) mortuary admission femoral blood drug concentrations f
Autor:
Alex K. Lyashchenko, Serge Cremers
Publikováno v:
Br J Clin Pharmacol
Personalization of oral small molecule anticancer drug doses based on individual patient blood drug levels, also known as therapeutic drug monitoring (TDM), has the potential to significantly improve the effectiveness of treatment by maximizing drug
Publikováno v:
ACS Applied Nano Materials. 3:5928-5935
Direct detection of drugs in the blood contributes to the study of pharmacokinetics, whereas low-concentration blood drug makes this goal challenging. Here, silver nanoparticles (AgNPs) are used fo...
Autor:
John M. Thomason, Andrew J. Mackin, Todd M. Archer, Charlee Mulligan, Crisanta Cruz-Espindola, Caitlin Riggs, Lakshmi Narayanan, Dawn M. Boothe, Roy Harmon, Claire L. Fellman, Robert W. Wills
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 34, Iss 3, Pp 1206-1213 (2020)
Journal of Veterinary Internal Medicine
Journal of Veterinary Internal Medicine
Background Dogs are often adminstered >1 immunosuppressive medication when treating immune‐mediated diseases, and determining whether these different medications affect IL‐2 expression would be useful when performing pharmacodynamic monitoring du
Publikováno v:
Jurnal Administrasi Negara. 25:176-193
Clinical pharmacy service is one of the patient-oriented health services so that it needs to be done in accordance with clinical pharmacy service standards to create quality and quality services. The purpose of this study was intended to find out how