Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Blood drug"'
Autor:
Idris Kirhan, Ataman Gönel
Publikováno v:
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry. 20:101-105
Background: Antibiotics used parenterally can affect blood drug level measurements, as measured in diagnostic tests. Objective: To investigate the effect of six different antibiotics commonly used in intensive care units on tacrolimus, sirolimus, eve
Autor:
Krasimira Prodanova
Publikováno v:
International Journal Bioautomation, Vol 24, Iss 4, Pp 337-348 (2020)
For the multiple drug administration from therapeutic reasons it is important to maintain the concentration in the blood plasma in an appropriate range. In the present paper an optimization approach is developed to determine drug dosage regimen to ac
Autor:
Alex K. Lyashchenko, Serge Cremers
Publikováno v:
Br J Clin Pharmacol
Personalization of oral small molecule anticancer drug doses based on individual patient blood drug levels, also known as therapeutic drug monitoring (TDM), has the potential to significantly improve the effectiveness of treatment by maximizing drug
Autor:
John M. Thomason, Andrew J. Mackin, Todd M. Archer, Charlee Mulligan, Crisanta Cruz-Espindola, Caitlin Riggs, Lakshmi Narayanan, Dawn M. Boothe, Roy Harmon, Claire L. Fellman, Robert W. Wills
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 34, Iss 3, Pp 1206-1213 (2020)
Journal of Veterinary Internal Medicine
Journal of Veterinary Internal Medicine
Background Dogs are often adminstered >1 immunosuppressive medication when treating immune‐mediated diseases, and determining whether these different medications affect IL‐2 expression would be useful when performing pharmacodynamic monitoring du
Publikováno v:
Biomedical Chromatography. 35
Delivery of already existing and new drugs under development to the brain necessitates passage across the blood-brain barrier (BBB) with its tight intercellular junctions, molecular components and transporter systems. Consequently, it is critical to
Publikováno v:
Antimicrob Agents Chemother
Kosmidis, C, Otu, A, Moore, C B, Richardson, M & Rautemaa-Richardson, R 2020, ' Isavuconazole therapeutic drug monitoring during long-term treatment for chronic pulmonary aspergillosis ', Antimicrobial Agents and Chemotherapy, vol. 65, no. 1, e01511-20 . https://doi.org/10.1128/AAC.01511-20
Kosmidis, C, Otu, A, Moore, C B, Richardson, M & Rautemaa-Richardson, R 2020, ' Isavuconazole therapeutic drug monitoring during long-term treatment for chronic pulmonary aspergillosis ', Antimicrobial Agents and Chemotherapy, vol. 65, no. 1, e01511-20 . https://doi.org/10.1128/AAC.01511-20
Isavuconazole is the newest triazole antifungal, and it displays a favorable pharmacokinetic and safety profile. Less is known about its long-term use in immunocompetent hosts. We performed a retrospective service evaluation of isavuconazole therapeu
Autor:
Thomas Dörner, Eva Schrezenmeier
Publikováno v:
Nature reviews. Rheumatology. 16(3)
Despite widespread clinical use of antimalarial drugs such as hydroxychloroquine and chloroquine in the treatment of rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) and other inflammatory rheumatic diseases, insights into the mechanism
Autor:
XuanWang, Yi-Fan Zhang, Gegentana, Shu-Jie Shen, Feng Xu, Guang-Xue Liu, Shao-Qing Cai, Feng-Chun Li, Ming-Ying Shang, Ping Yang, Yao-Li Li, Xin-Xin Yang
Publikováno v:
Journal of Ethnopharmacology. 258:112886
Ethnopharmacological relevance This study addresses the rapid discovery of the active compounds (the original constituents and/or metabolites) of a traditional Chinese drug, Smilacis Glabrae Rhizoma (SGR). Aim of the study The aim of this study was t
Publikováno v:
Analytica Chimica Acta. 1151:338250
Clinical vancomycin (Van) treatment is administered over a prolonged period to achieve a sustained therapeutic effect. Accurate, rapid, and continuous Van detection is an unmet medical monitoring need that can provide data-based guidance for doctors
Autor:
Nicolas Picard, Vincent Haufroid
Publikováno v:
Therapeutic drug monitoring, p. [1-10] (2018)
Conventional therapeutic drug monitoring refers to the individualization of drug dosage by maintaining plasma or blood drug concentrations within a targeted therapeutic range. Accordingly, an individualized dose is proposed to the clinician according