Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Blood drug"'
HSA-Lys-161 covalent bound fluorescent dye for in vivo blood drug dynamic imaging and tumor mapping†
Autor:
Caixia Yin, Yongkang Yue, tingting zhao, Fangqin Cheng, Ma Kaiqing, Wu Xingkang, Yuting Wang, Fangjun Huo
Publikováno v:
Chemical Science
The specific combination of human serum albumin and fluorescent dye will endow superior performance to a coupled fluorescent platform for in vivo fluorescence labeling. In this study, we found that lysine-161 in human serum albumin is a covalent bind
Autor:
XuanWang, Yi-Fan Zhang, Gegentana, Shu-Jie Shen, Feng Xu, Guang-Xue Liu, Shao-Qing Cai, Feng-Chun Li, Ming-Ying Shang, Ping Yang, Yao-Li Li, Xin-Xin Yang
Publikováno v:
Journal of Ethnopharmacology. 258:112886
Ethnopharmacological relevance This study addresses the rapid discovery of the active compounds (the original constituents and/or metabolites) of a traditional Chinese drug, Smilacis Glabrae Rhizoma (SGR). Aim of the study The aim of this study was t
Publikováno v:
Analytica Chimica Acta. 1151:338250
Clinical vancomycin (Van) treatment is administered over a prolonged period to achieve a sustained therapeutic effect. Accurate, rapid, and continuous Van detection is an unmet medical monitoring need that can provide data-based guidance for doctors
Publikováno v:
Chinese Medical Journal
Chinese Medical Journal, Vol 129, Iss 2, Pp 194-199 (2016)
Chinese Medical Journal, Vol 129, Iss 2, Pp 194-199 (2016)
Background: Recently, local sustained-release antibiotics systems have been developed because they can increase local foci of concentrated antibiotics without increasing the plasma concentration, and thereby effectively decrease any systemic toxicity
Autor:
Odile Dewit, Chao Chen, Jill C. Richardson, Simon M. McHugh, Paul Scott-Stevens, Bart Laurijssens, Zahid Ali, Anastasia Stylianou, Thor Ostenfeld, Louise Hosking
Publikováno v:
British Journal of Clinical Pharmacology. 75:197-207
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • P2X7 receptors are involved in the production of pro-inflammatory cytokines, such as Il-1β, by central and peripheral immune cells. Il-1β has been implicated as an important mediator of inflammation. The
Publikováno v:
Biological and Pharmaceutical Bulletin. 31:1985-1989
Nafamostat mesilate, an ester drug with extensive hydrolysis in vivo, exhibits species difference in the relative contribution for its hydrolysis in blood and tissues. For the rat, the main hydrolysis site may be blood and human may be tissue (mainly
Publikováno v:
Journal of Materials Science: Materials in Medicine. 26
A suitable drug-loaded scaffold that can postoperatively release an antituberculosis drug efficiently in a lesion area and help repair a bone defect is very important in the clinical treatment of bone tuberculosis (TB). In this study, a composite dru
Autor:
Ying Li, Mingyuang Li, Xiangyang Xie, Wen Lin, Chuanfeng Xing, Hui Zhang, Zhenbo Yang, Yanfang Yang, Yang Yang, Qiang Chi, Zhiping Li
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 5, p e0125953 (2015)
PLoS ONE, Vol 10, Iss 5, p e0125953 (2015)
Poor patient compliance, untoward reactions and unstable blood drug levels after the bolus administration are impeding the pharmacotherapy for insobriety. A long-acting preparation may address these limitations. The aim of this paper was to further i
Publikováno v:
Drug Delivery. 12:27-33
The aim of the study was to determine penetration properties of Famotidine fro the formulations through colon adenocarcinoma (Caco)-2 cell monolayers and to compare in vitro with in vivo test results. It also aimed to determine the effect of particle
Publikováno v:
International journal of pharmaceutics. 456(2)
This study aims to investigate the feasibility of Levodopa transdermal delivery systems (TDSs). Levodopa TDSs were formulated using various vehicles and permeation enhancers, and in vitro permeation and in vivo pharmacokinetic studies were carried ou