Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Blood drug"'
HSA-Lys-161 covalent bound fluorescent dye for in vivo blood drug dynamic imaging and tumor mapping†
Autor:
Caixia Yin, Yongkang Yue, tingting zhao, Fangqin Cheng, Ma Kaiqing, Wu Xingkang, Yuting Wang, Fangjun Huo
Publikováno v:
Chemical Science
The specific combination of human serum albumin and fluorescent dye will endow superior performance to a coupled fluorescent platform for in vivo fluorescence labeling. In this study, we found that lysine-161 in human serum albumin is a covalent bind
Autor:
Idris Kirhan, Ataman Gönel
Publikováno v:
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry. 20:101-105
Background: Antibiotics used parenterally can affect blood drug level measurements, as measured in diagnostic tests. Objective: To investigate the effect of six different antibiotics commonly used in intensive care units on tacrolimus, sirolimus, eve
Publikováno v:
Biomedical Chromatography. 35
Delivery of already existing and new drugs under development to the brain necessitates passage across the blood-brain barrier (BBB) with its tight intercellular junctions, molecular components and transporter systems. Consequently, it is critical to
Publikováno v:
Russian journal of hematology and transfusiology. 64:73-78
Aim. To present a technique for obtaining fibrinogen concentrate purified from ballast proteins, which can be used in hemostatic drug production.Materials and methods. The proposed method is based on isolating fibrinogen from a cryoprecipitate soluti
Autor:
Jae Young Lee, Yong Suk Jin, Zion Kang, Min-Soo Kim, Seong Hoon Jeong, Joo Won Park, Min-Hyo Seo, Sa-Won Lee, Sang Yeob Park, Hye Jung Lim, Prakash Thapa
Publikováno v:
International Journal of Pharmaceutics. 566:229-238
Sorafenib, a potent anticancer drug, has low absorption in the gastrointestinal tract due to its poor aqueous solubility. The main purpose of this investigation was to design sorafenib nanoparticle using a newly developed technique, nanoparticulation
Autor:
Xuebin Wang, Min Cai, Lishui Wang, Binhu Liu, Guangyuan Cao, Zhuo Wang, Jiafei Dong, Fengbo Wu, Zhaorui Wang
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 205:114290
Accurate quantification of low level of blood drugs by Latex enhanced immunoturbidimetric assay (LEITA) remains a challenge due to its inherent limited sensitivity. To deal with this problem, we designed a new agglutination-enhancement strategy, and
Autor:
XuanWang, Yi-Fan Zhang, Gegentana, Shu-Jie Shen, Feng Xu, Guang-Xue Liu, Shao-Qing Cai, Feng-Chun Li, Ming-Ying Shang, Ping Yang, Yao-Li Li, Xin-Xin Yang
Publikováno v:
Journal of Ethnopharmacology. 258:112886
Ethnopharmacological relevance This study addresses the rapid discovery of the active compounds (the original constituents and/or metabolites) of a traditional Chinese drug, Smilacis Glabrae Rhizoma (SGR). Aim of the study The aim of this study was t
Publikováno v:
Analytica Chimica Acta. 1151:338250
Clinical vancomycin (Van) treatment is administered over a prolonged period to achieve a sustained therapeutic effect. Accurate, rapid, and continuous Van detection is an unmet medical monitoring need that can provide data-based guidance for doctors
Autor:
Esteban Otero-Antón, Carmen Cadarso-Suárez, Manuel López-Rivadulla, Elena Lendoiro, Angelines Cruz, Lucía Paniagua-González, Ana de-Castro-Ríos, Carla Díaz-Louzao
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 189:113422
Therapeutic drug monitoring (TDM) of immunosuppressants (IMS) is crucial to prevent rejection or toxicity after solid organ transplantation. Microsampling techniques (sampling
Publikováno v:
Chinese Medical Journal
Chinese Medical Journal, Vol 129, Iss 2, Pp 194-199 (2016)
Chinese Medical Journal, Vol 129, Iss 2, Pp 194-199 (2016)
Background: Recently, local sustained-release antibiotics systems have been developed because they can increase local foci of concentrated antibiotics without increasing the plasma concentration, and thereby effectively decrease any systemic toxicity