Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Cory Abate-Shen"'
Autor:
Cory Abate-Shen, Amir Lankarani, Matteo Di Bernardo, Michael M. Shen, Rivka L. Shoulson, Soonbum Park, Lijie Rong, Tomasz Owczarek, Talal Syed, Hikmat Al-Ahmadie, David B. Solit, James M. McKiernan, Chee-Wai Chua, Prithi Chakrapani, Jaime Y. Kim
Publikováno v:
Cancer Res
To study the progression of bladder cancer from non–muscle-invasive to muscle-invasive disease, we have developed a novel toolkit that uses complementary approaches to achieve gene recombination in specific cell populations in the bladder urotheliu
Autor:
Christopher B. Anderson, James M. McKiernan, Jamie S. Pak, Cory Abate-Shen, G. Joel DeCastro, Izak Faiena, Helena Vila-Reyes, Kevin C. Lee, Gen Li
Publikováno v:
Journal of Urology. 203
INTRODUCTION AND OBJECTIVE:Guidelines recommend radical cystectomy (RC) as first-line treatment for BCG-unresponsive bladder cancer (BCa). However, many patients are unfit or refuse RC. We report a...
Autor:
Charles G. Drake, Cory Abate-Shen, Guarionex Joel DeCastro, Max M. Kates, Renu K. Virk, Christopher B. Anderson, Bridget James, Wilson Sui, Dara Holder, Jamie S. Pak, Shing M. Lee, James M. McKiernan
Publikováno v:
The Journal of urology. 204(2)
For patients with bacillus Calmette-Guérin unresponsive or recurrent/relapsing nonmuscle invasive bladder cancer, multi-agent intravesical trials have been limited. In this study we investigate the safety of intravesical cabazitaxel, gemcitabine and
Autor:
Lijie Rong, Cory Abate-Shen
Publikováno v:
Clinical Cancer Research. 26:A28-A28
Cell differentiation and plasticity is precisely controlled by specific gene expression programs coordinate with chromatin remodeling, which are often deregulated during tumorigenesis. While divergent histopathologic differentiation in bladder cancer
Autor:
Suk Hyung Lee, Hikmat Al-Ahmadie, Alanna B. Williams, James M. McKiernan, Cory Abate-Shen, Wenhuo Hu, Mitchell C. Benson, Mark V. Silva, Barry S. Taylor, Kwanghee Kim, Eugene J. Pietzak, Sarah K. Bergren, La Mont J. Barlow, Christopher B. Anderson, Jonathan A. Coleman, Cyriac Kandoth, David B. Solit, Michael M. Shen, Justin T. Matulay, Chee Wai Chua, Tomasz Owczarek
Publikováno v:
Cell. 173(2)
Summary Bladder cancer is the fifth most prevalent cancer in the U.S., yet is understudied, and few laboratory models exist that reflect the biology of the human disease. Here, we describe a biobank of patient-derived organoid lines that recapitulate
Publikováno v:
Oncotarget
There is a critical need to identify treatment options for patients at high risk for developing muscle invasive bladder cancer that avoid surgical removal of the bladder (cystectomy). In the current study, we have performed preclinical studies to inv
Autor:
Ifeanyi Onyeji, Jennifer Ahn, Danny Lascano, Guarionex Joel DeCastro, James M. McKiernan, Cory Abate-Shen, Arindham RoyChoudhury, Dara Holder
Publikováno v:
The Lens
The prognosis and treatment of bladder cancer have improved little in the past 20 years. Bladder cancer remains a debilitating and often fatal disease, and is among the most costly cancers to treat. The generation of informative mouse models has the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::715a647fb21d51523854ea54d2d77cdb
https://europepmc.org/articles/PMC4386904/
https://europepmc.org/articles/PMC4386904/
Autor:
Ifeanyi Onyeji, Guarionex Joel DeCastro, Arindam RoyChoudhury, Dara Holder, Sam S. Chang, Danny Lascano, James M. McKiernan, Jennifer Ahn, Cory Abate-Shen, Neil Desai
Publikováno v:
Journal of Clinical Oncology. 34:e16008-e16008
e16008Background: Up to 40% of patients treated with intravesical agents for non-muscle invasive bladder cancer (NMIBC) will recur. Our lab has previously demonstrated the feasibility of mTOR inhib...
Publikováno v:
Journal of Urology. 187
INTRODUCTION AND OBJECTIVES: Although most superficial bladder cancers can be removed transurethrally with excellent prognosis, clinical outcome is much more problematic for patients with muscle-invasive disease. Indeed, invasive bladder cancer is a