Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Koichi Abe"'
Autor:
Taro Saito, Yutaka Shimizu, Kaori Tsukakoshi, Koichi Abe, Jinhee Lee, Kinuko Ueno, Ryutaro Asano, Brian V. Jones, Tomohiro Yamada, Tatsuki Nakano, Jiaxing Tong, Asami Hishiki, Kodai Hara, Hiroshi Hashimoto, Koji Sode, Toshimasa Toyo’oka, Kenichiro Todoroki, Kazunori Ikebukuro
Publikováno v:
Biosensorsbioelectronics. 203
Therapeutic monoclonal antibodies (mAbs) are successful biomedicines; however, evaluation of their pharmacokinetics and pharmacodynamics demands highly specific discrimination from human immunoglobulin G naturally present in the blood. Here, we devel
Autor:
Wataru Yoshida, Nasa Savory, Kaori Tsukakoshi, Koichi Abe, Kazunori Ikebukuro, Tomomi Yokoyama, Taiki Saito, Kentaro Teramoto
Publikováno v:
Biotechnology and Bioengineering. 114:2196-2203
We describe the selection of aptamers based on bioinformatics-based approaches without Systematic Evolution of Ligands by EXponential enrichment (SELEX). SELEX is a potent method; however, it is time intensive and the PCR-amplification step, which is
Autor:
Yoshio Kato, Kazunori Ikebukuro, Kaori Tsukakoshi, Chikashi Nakamura, Jinhee Lee, Koichi Abe, Ayana Yamagishi, Daisuke Matsumoto, Maui Nishio
Publikováno v:
Biosensors and Bioelectronics. 93:26-31
Genome editing with site-specific nucleases (SSNs) can modify only the target gene and may be effective for gene therapy. The main limitation of genome editing for clinical use is off-target effects; excess SSNs in the cells and their longevity can c
Autor:
Wataru Yoshida, Kazunori Ikebukuro, Nasa Savory, Takahiro Fukaya, Koichi Abe, Koji Sode, Stefano Ferri, Kaori Tsukakoshi
Publikováno v:
Journal of Biotechnology. 212:99-105
Aptamers are mainly selected by in vitro selection using random nucleic acid libraries. These aptamers have often shown insufficient affinity for biomedical applications. We improved DNA aptamer binding affinity for vascular endothelial growth factor
Autor:
Wataru Yoshida, Kenichiro Hata, Koji Sode, Kazunori Ikebukuro, Koichi Abe, Christophe A. Marquette, Kazuhiko Nakabayashi, Hironobu Wakeda, Jinhee Lee, Loïc J. Blum
Publikováno v:
Biosensors and Bioelectronics
Biosensors and Bioelectronics, Elsevier, 2016, 93, pp.118-123. ⟨10.1016/j.bios.2016.09.060⟩
Biosensors and Bioelectronics, Elsevier, 2016, 93, pp.118-123. ⟨10.1016/j.bios.2016.09.060⟩
International audience; DNA methylation level at a certain gene region is considered as a new type of biomarker for diagnosis and its miniaturized and rapid detection system is required for diagnosis. Here we have developed a simple electrochemical d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bea2235acc0474d26702c0bd5c40070
https://hal.archives-ouvertes.fr/hal-01483845
https://hal.archives-ouvertes.fr/hal-01483845
Autor:
Mayumi Nakamura, Koichi Abe, Kazunori Ikebukuro, Koji Sode, Kotone Miyake, Stefano Ferri, Katsuhiro Kojima
Publikováno v:
Microbial Biotechnology
In order to construct a green-light-regulated gene expression system for cyanobacteria, we characterized a green-light sensing system derived from Synechocystis sp. PCC6803, consisting of the green-light sensing histidine kinase CcaS, the cognate res
Autor:
Madoka Takase, Stefano Ferri, Yayoi Takahashi, Nasa Savory, Koichi Abe, Koji Sode, Kaori Tsukakoshi, Kazunori Ikebukuro, Wataru Yoshida, Hijiri Hasegawa, Shizuko Kumazawa
Publikováno v:
Biotechnology and Bioengineering. 111:454-461
In silico evolution with an in vitro system can facilitate the development of functional aptamers with high specificity and affinity. Although a general technique known as systematic evolution of ligand by exponential enrichment (SELEX) is an efficie
Autor:
Danielle Lednor, Nasa Savory, Stefano Ferri, Wataru Yoshida, Kaori Tsukakoshi, Brian V. Jones, Kazunori Ikebukuro, Koichi Abe
Publikováno v:
Biotechnology and Bioengineering. 110:2573-2580
Proteus mirabilis is a prominent cause of catheter-associated urinary tract infections (CAUTIs) among patients undergoing long-term bladder catheterization. There are currently no effective means of preventing P. mirabilis infections, and strategies
Publikováno v:
Microbial Cell Factories
Recent advances in the understanding of photosensing in biological systems have enabled the use of photoreceptors as novel genetic tools. Exploiting various photoreceptors that cyanobacteria possess, a green light-inducible gene expression system was
Publikováno v:
Biotechnology Letters. 32:1293-1298
Motif analysis of PGa4 indicated that eight consecutive guanine residues were most important for pyrroloquinoline quinine glucose dehydrogenase (PQQGDH) recognition. Because the truncated mutants minimized unexpected interactions between PGa4 and the