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Autor:
Shigeru Hayashi, Kenji Sakai, Takayuki Nojima, Masanao Mohri, Makoto Mori, Masahito Yamada, Katsuhiko Saito, Keitaro Matsubara
Publikováno v:
Internal Medicine. 61:1903-1906
We herein report a 73-year-old man with isolated hypertrophic pachymeningitis (HP) showing serological and pathological characteristics of both IgG4-related disorders and granulomatosis with polyangiitis. The patient presented with chronic onset head
Autor:
Daigo Hashimoto, Nanase Okazaki, Masahiro Onozawa, Junichi Sugita, Daisuke Hidaka, Shinichi Fujisawa, Atsushi Yasumoto, Keito Suto, Naoki Miyashita, Hiroyuki Ohigashi, Yoshihiro Matsuno, Takanori Teshima
Publikováno v:
Internal Medicine. 61:1049-1054
Right neck swelling and pain occurred in a 49-year-old man. A Blood count showed a slight increase in platelet count without leukemoid reaction. After a biopsy of the cervical mass and bone marrow aspiration, a diagnosis of extramedullary blast crisi
Autor:
Ilseon Hwang, Sung Uk Bae, Soon Gu Kim, Jae-Ho Lee, Sun Young Kwon, Sang Jun Byun, Hyunseung Oh, Shin Kim, Hye Won Lee
Publikováno v:
Journal of Pathology and Translational Medicine, Vol 56, Iss 1, Pp 40-47 (2022)
Journal of Pathology and Translational Medicine
Journal of Pathology and Translational Medicine
Background: Polo-like kinase 4 (PLK4) is a serine/threonine protein kinase located in the centriole of the chromosome during the cell cycle. PLK4 overexpression has been described in a variety of many common human epithelial tumors. Conversely, PLK4
Autor:
Mitsuharu Ueda, Per Westermark, Maria M. Picken, Thibaud Damy, Bouke P. C. Hazenberg, Stefan Schönland, John L. Berk, Julian D. Gillmore, Angela Dispenzieri, Merrill D. Benson, Christoph Röcken, Francesca Lavatelli
Publikováno v:
Amyloid, 29(1), 8-13. Taylor & Francis Ltd
A reliable diagnosis of amyloidosis is usually based on a tissue biopsy. With increasing options for specific treatments of the different amyloid diseases, an exact and valid diagnosis including determination of the biochemical fibril nature is imper
Autor:
Masaaki Nakayama, Koyu Suzuki, Kimio Watanabe, Kasumi Konishi, Yugo Ito, Takuya Fujimaru, Sho Fukui, Fumika Taki, Masahiko Nagahama
Publikováno v:
CEN Case Rep
A 37-year-old African–British man was referred to our hospital for detailed examination because of persistent fever, swelling and pain in both ankle joints, and blurred vision for two months. Inguinal lymph node biopsy showed a large number of epit
Autor:
Karina Aivazian, Andrew J. Spillane, Mary-Ann El Sharouni, Richard A. Scolyer, Tasnia Ahmed, John F. Thompson, Robyn P. M. Saw, Sydney Ch'ng, Kerwin F. Shannon, Omgo E. Nieweg, Jonathan R. Stretch, Serigne Lo
Publikováno v:
Modern Pathology. 34:1999-2008
Regression in melanoma is an immunological phenomenon that results in partial or complete replacement of the tumor with variably vascular fibrous tissue, often accompanied by pigment-laden macrophages and chronic inflammation. In some cases, tumor-in
Publikováno v:
Internal Medicine
Malignant peritoneal mesothelioma (MPM) is a rare malignant tumor with peritoneal thickening. Tuberculous peritonitis also shows peritoneal thickening, so differentiating between the two is important but difficult if latent tuberculosis infection (LT
Autor:
Shinpei Doi, Takayuki Tsujikawa, Go Saito, Hiromichi Tsunashima, Takako Adachi, Tomohiro Kikuyama, Ayako Watanabe, Kotaro Matsumoto, Ken Sato, Kentaro Kikuchi
Publikováno v:
Internal Medicine
An 80-year-old woman was admitted to our hospital due to appetite loss and vomiting. A blood examination showed liver disorder with disseminated intravascular coagulation. All tumor markers and hepatitis virus markers were negative. Contrast-enhanced
Autor:
Ashkan Rezazadeh Ardabili, Heike I. Grabsch, Daisy Jonkers, Mariëlle Romberg-Camps, Danny Goudkade, Bjorn Winkens, Marie J. Pierik, Dion S J Wintjens
Publikováno v:
Journal of Crohn's & Colitis, 15(11), 1885-1897. Oxford University Press
Journal of Crohn's & Colitis
Journal of Crohn's & Colitis
Background and Aims Crohn’s disease [CD] is characterised by a heterogeneous disease course. Patient stratification at diagnosis using clinical, serological, or genetic markers does not predict disease course sufficiently to facilitate clinical dec
Autor:
Dai Hashimoto, Masato Kono, Hidenori Nakamura, Akari Tsutsumi, Ryutaro Hirama, Yuiko Ohshima, Kenichiro Takeda, Yoshihiro Miki, Toshiki Kimura, Hideki Miwa, Yasutaka Mochizuka, Takuro Sakagami
Publikováno v:
Internal Medicine. 60:3267-3272
A 78-year-old man was admitted to our hospital with a fever and left chest pain. Computed tomography showed multiple lung nodules, narrowing of the right bronchus intermedius with mediastinal lymphadenopathy, and an osteolytic lesion. Bronchoscopic f