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of 38
pro vyhledávání: '"Neil K. Gibbs"'
A potential role for endogenous proteins as sacrificial sunscreens and antioxidants in human tissues
Autor:
Rachel E.B. Watson, Sarah A. Hibbert, Christopher E.M. Griffiths, Neil K. Gibbs, Anthony S. Weiss, Patrick Costello, Clair Baldock, Michael J. Sherratt
Publikováno v:
Redox Biology, Vol 5, Iss, Pp 101-113 (2015)
Redox Biology
Redox Biology
Excessive ultraviolet radiation (UVR) exposure of the skin is associated with adverse clinical outcomes. Although both exogenous sunscreens and endogenous tissue components (including melanins and tryptophan-derived compounds) reduce UVR penetration,
Low-dose ultraviolet radiation selectively degrades chromophore-rich extracellular matrix components
Autor:
Siobhan M Reilly, Michael J. Sherratt, Rachel E.B. Watson, Neil K. Gibbs, Christopher P Bayley, Christopher E.M. Griffiths
Publikováno v:
The Journal of Pathology. 222:32-40
Photoageing of human skin due to chronic exposure to ultraviolet radiation (UVR) is characterized histologically by extensive remodelling of the dermal elastic fibre system. Whilst enzymatic pathways are thought to play a major role in mediating extr
Autor:
Neil K. Gibbs, Samantha Kidd, Nicola J. Traynor, Laurent Marrot, Jean Roch Meunier, Catherine Agapakis-Causse
Publikováno v:
Journal of Photochemistry and Photobiology B: Biology. 58:26-31
The fluoroquinolone antibiotic, lomefloxacin, is phototoxic in human skin exposed to UVA radiation, photosensitises DNA strand breaks and pyrimidine dimers in human keratinocytes in vitro, and is phototumorigenic in mouse skin. The p53 tumour suppres
Publikováno v:
Journal of Photochemistry and Photobiology B: Biology. 34:63-66
Trans to cis photoisomerization of epidermal urocanic acid (UCA) has been proposed as a primary event in UV-induced immunosuppression. 8-Methoxypsoralen (8-MOP) in combination with UVA radiation (PUVA) is used for photochemotherapy of several immunol
Autor:
Christopher E.M. Griffiths, Rachel E.B. Watson, Sarah Thurstan, Michael J. Sherratt, A.K. Langton, Neil K. Gibbs
Publikováno v:
Chemistry Central Journal
Thurstan, S, Gibbs, N K, Langton, A K, Griffiths, C E M, Watson, R E B & Sherratt, M J 2012, ' Chemical consequences of cutaneous photoageing ', Chemistry Central Journal, vol. 6, no. 1, 34 . https://doi.org/10.1186/1752-153X-6-34
Chemistry Central Journal, Vol 6, Iss 1, p 34 (2012)
Thurstan, S, Gibbs, N K, Langton, A K, Griffiths, C E M, Watson, R E B & Sherratt, M J 2012, ' Chemical consequences of cutaneous photoageing ', Chemistry Central Journal, vol. 6, no. 1, 34 . https://doi.org/10.1186/1752-153X-6-34
Chemistry Central Journal, Vol 6, Iss 1, p 34 (2012)
Human skin, in common with other organs, ages as a consequence of the passage of time, but in areas exposed to solar ultraviolet radiation, the effects of this intrinsic ageing process are exacerbated. In particular, both the severity and speed of on
Autor:
Francesco Dall'Acqua, Neil K. Gibbs, C. D. Jones, Ali A. El-Ghorr, Y. Sontag, H. van Loveren, J. Garssen, F.R. de Gruijl, C. De Simone, D. Cerimele, Sergio Caffieri, Mary Norval
Publikováno v:
Journal of photochemistry and photobiology. B, Biology. 42(3)
Exposure to UV light has, besides some beneficial effects (vitamin D production), many harmful effects on human health. UVB irradiation has been shown to suppress both systemic and local immune responses to a variety of antigens, including some micro
Publikováno v:
Photochemistry and photobiology. 62(2)
Cis-urocanic acid (UCA), formed in the epidermis by UV irradiation of trans-UCA, has been implicated as a mediator of the immunosuppression induced by UV exposure of the skin. This review covers recent work in which the wavelength dependence of cis-U
Autor:
Neil K. Gibbs
Publikováno v:
Journal of Photochemistry and Photobiology B: Biology. 39:III-IV
Autor:
Neil K. Gibbs
Publikováno v:
Journal of Photochemistry and Photobiology B: Biology. 38:III-IV
Autor:
Neil K. Gibbs
Publikováno v:
Journal of Photochemistry and Photobiology B: Biology. 33:99-100