Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Hiroaki Konishi"'
Autor:
Tasuku Nishino, Takaya Abe, Mari Kaneko, Masanao Yokohira, Keiko Yamakawa, Katsumi Imaida, Hiroaki Konishi
Publikováno v:
Biochemical and Biophysical Research Communications. 628:91-97
The adaptor protein GAREM has two subtypes. Each is involved in Erk activation signaling downstream of the cell growth factor receptor in cultured cells. Regarding their role in individual animals, we have previously reported that mice deficient in G
Autor:
Yu Kimura, Teruyuki Kondo, Natsuki Matsumoto, Hisatsugu Yamada, Aoi Son, Hiroaki Konishi, Tetsuya Matsuda, Hirohiko Imai, Yasuhiro Aoyama, Takanori Komaki
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
Three-dimensional (3D) representation of a tumor with respect to its size, shape, location, and boundaries is still a challenge in photoacoustic (PA) imaging using artificial contrast agents as probes. We carried out PA imaging of tumors in mice usin
Autor:
Shuhei Takauji, Hiroki Tanaka, Shotaro Isozaki, Kie Horioka, Hiroaki Konishi, Mineji Hayakawa
Publikováno v:
Biochemical and biophysical research communications. 587
Background Accidental hypothermia (AH) sometimes leads to coagulation disorder, especially in severe AH. We previously demonstrated that intrasplenic platelet activation caused aberrant hemostasis and thrombus formation after rewarming in a murine AH
Receptor-based fluorescent sensors are the representative tool for quantitative detection of target ligands. The high substrate-selectivity originated from biomacromolecule receptor is one of the advantages of this tool, but a laborious trial and err
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::488406dfee5d3c13c74826c38508dfc7
https://doi.org/10.1016/bs.mie.2020.04.041
https://doi.org/10.1016/bs.mie.2020.04.041
Autor:
Yutaka Kohgo, Hiroki Tanabe, Nobuhiro Ueno, Junpei Sasajima, Kentaro Moriichi, Hiroki Tanaka, Katsuya Ikuta, Mikihiro Fujiya, Hiroaki Konishi
Publikováno v:
Biochemical and Biophysical Research Communications. 467:847-852
While the progress of chemotherapy and molecular targeted therapy has improved the outcome of colorectal cancer patients, the mortality of colon cancer remains high, indicating the need to develop novel therapeutic targets for improving the outcome o
Publikováno v:
Biochemical and biophysical research communications. 495(1)
Cardiolipin and phosphatidic acid-binding protein (CLPABP) controls the stability of the mRNA harboring an AU-rich element (ARE) in the 3' UTR with the help of the RNA stabilizer, human antigen R (HuR). Although CLPABP is localized on the mitochondri
Publikováno v:
Biochemical and Biophysical Research Communications. 464:616-621
GAREM1 (Grb2-associated regulator of Erk/MAPK1) is an adaptor protein that is involved in the epidermal growth factor (EGF) pathway. The nuclear localization of GAREM1 depends on the nuclear localization sequence (NLS), which is located at the N-term
Publikováno v:
FEBS Letters. 586:2245-2250
Although SPE-39 is a binding protein to Vps33B that is one of the subunit in the mammalian HOPS complex, the elements of SPE-39 function remain unknown. Here, we show that tyrosine phosphorylation of SPE-39 following EGF stimulation plays a role in t
Autor:
Ryota Matsunaga, Atsushi Yokoyama, Ushio Kikkawa, Hiroaki Konishi, Akio Nakashima, Tasuku Nishino
Publikováno v:
Biochemical and biophysical research communications. 469(3)
The CLOCK-interacting protein, Circadian (CIPC), has been identified as an additional negative-feedback regulator of the circadian clock. However, recent study on CIPC knockout mice has shown that CIPC is not critically required for basic circadian c
Autor:
Junpei Sasajima, Mikihiro Fujiya, Hiroki Tanabe, Shin Kashima, Kentaro Moriichi, Nobuhiro Ueno, Yutaka Kohgo, Kazuyuki Tanaka, Hiroaki Konishi, Katsuya Ikuta
Publikováno v:
Biochemical and biophysical research communications. 467(3)
Probiotics exhibit beneficial functions for host homeostasis maintenance. We herein investigated the mechanism by which Lactobacillus brevis-derived poly P exhibited a beneficial function. Immunostaining indicated that poly P was captured in the plas