Zobrazeno 1 - 4
of 4
pro vyhledávání: '"William C. Hunter"'
Publikováno v:
Europe PubMed Central
Length-dependent steady-state and dynamic responses of five models of isometric force generation in cardiac myofilaments were compared with similar experimental data from the literature. The models were constructed by assuming different subsets of th
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 286(4)
To describe the dynamics of constantly activated cardiac muscle, we propose that length affects force via both recruitment and distortion of myosin cross bridges. This hypothesis was quantitatively tested for descriptive and explanative validity. Ski
Publikováno v:
Journal of biomechanics. 30(2)
Active tension developed while cardiac muscle shortens has been studied extensively under afterloaded isotonic or isovelocity conditions. However, these are not true in vivo loading conditions. To obtain more physiological loading, we controlled sarc
Autor:
Paul M.L. Janssen, William C. Hunter
Publikováno v:
The American journal of physiology. 269(2 Pt 2)
Recent studies have emphasized the importance of the late systolic phase for understanding ventricular ejection. To examine the myocardial factors controlling this phase, we studied the timing of twitch contraction in nine excised rat trabeculae cont