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of 6
pro vyhledávání: '"Ji-Sun Kim"'
Publikováno v:
Biochemical and biophysical research communications. 573
Fusion of a target-specific peptide to a full-length antibody (Ab) can result in a peptide–Ab fusion protein with additional specificity and enhanced activity. We recently developed an intracellular pan-RAS–targeting cytosol-penetrating antibody,
Publikováno v:
Biophysical Journal. 110(2):423-430
Lactophoricin (LPcin), a component of proteose peptone (113-135) isolated from bovine milk, is a cationic amphipathic antimicrobial peptide consisting of 23 amino acids. We designed a series of N- or C-terminal truncated variants, mutated analogs, an
Publikováno v:
Biophysical Journal. 108(2)
The availability of antibiotics has allowed for the successful treatment of many bacterial infections as well as the ability to perform invasive medical procedures including surgery and chemotherapy. However, their wide use has led to pathogens’ in
Publikováno v:
Biophysical Journal. 110:154a
The wide use of antibiotics has led to pathogens' increased drug resistance. Most of the drugs in development are analogs of earlier antibiotics which work on a select number of bacterial targets. There will be an increasing demand for novel drugs to
Publikováno v:
Biophysical journal. 101(5)
Lactophoricin (LPcin-I) is an antimicrobial, amphiphatic, cationic peptide with 23-amino acid residues isolated from bovine milk. Its analogous peptide, LPcin-II, lacks six N-terminal amino acids compared to LPcin-I. Interestingly, LPcin-II does not
Publikováno v:
Biophysical Journal. 106(2):192a-193a
Antibiotics from organic compounds are a long established part of our defense against bacterial pathogens. Their wide use has led to pathogens' increased drug resistance and the need to find novel classes of antimicrobial peptides as alternatives to