Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ye Zheng"'
Publikováno v:
Frontiers in Molecular Neuroscience
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Nitration of tyrosine at the tenth residue (Tyr10) in amyloid-β (Aβ) has been reported to reduce its aggregation and neurotoxicity in our previous studies. However, the exact mechanism remains unclear. Here, we used Aβ1–42 peptide with different
Autor:
Chun-Ye Zheng, Hong-Feng Liang, Xiao-Dong Luo, Ai-Ping Gu, Qiao-Zhen Su, Jun Cai, Xin-Chun Zhang, Hua-Jun Wang
Publikováno v:
Biochemical and Biophysical Research Communications. 502:269-275
Neuroinflammation plays a critical role in the process of neurodegenerative disorders, during which microglia, the principal resident immune cells in the central nervous system, are activated and produce proinflammatory mediators. Yin-Yang 1 (YY1), a
Publikováno v:
International Journal of Biological Macromolecules. 79:235-239
Calcineurin (CN) is a Ca(2+)/calmodulin (CaM) activated serine/threonine phosphatase, and its regulatory region (CNRR) plays a critical role in the coupling of Ca(2+) signals to cellular responses. Ca(2+)/CaM binds to the CNRR, resulting in a conform
Autor:
Thomas P. Burghardt, Miriam F. Halstead, Katalin Ajtai, Emma A. Morrison, Ye Zheng, Alan R. Penheiter, Joshua D. Spencer
Publikováno v:
Biophysical Journal. 93:3555-3566
The motor protein myosin binds actin and ATP, producing work by causing relative translation of the proteins while transducing ATP free energy. Smooth muscle myosin has one of four heavy chains encoded by the MYH11 gene that differ at the C-terminus
Publikováno v:
Biophysical Journal. 93(6):2226-2239
Myosin is the molecular motor in muscle-binding actin and executing a power stroke by rotating its lever arm through an angle of approximately 70 degrees to translate actin against resistive force. A green fluorescent protein (GFP)-tagged human cardi
An extensively associated dimer in the structure of the C713S mutant of the TIR domain of human TLR2
Publikováno v:
Biochemical and biophysical research communications. 299(2)
The Toll/interleukin-1 receptor (TIR) domains are conserved modules in the intracellular regions of the Toll-like receptors (TLRs) and interleukin-1 receptors (IL-1Rs). The domains are crucial for the signal transduction by these receptors, through h